Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
chloramphenicol acetyltransferase I
Overview
| Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|
| S155R | - | - | - | phenicols | Reslit | Candidate |
| T172L | - | - | - | phenicols | Reslit | Candidate |
| S27M | - | - | - | phenicols | Reslit | Candidate |
| Q30M | - | - | - | phenicols | Reslit | Candidate |
| G202R | - | - | - | phenicols | Reslit | Candidate |
| G202K | - | - | - | phenicols | Reslit | Candidate |
| P28A | - | - | - | phenicols | Reslit | Candidate |
Genes Vary Greatly in Their Propensity for Collateral Fitness Effects of Mutations.
CAT-I mutations affecting trimer formation and translation initiation caused deleterious collateral fitness effects
Mutations at active sites of CAT-I cause deleterious collateral fitness effects.