Cj0843c

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putative lytic transglycosylase

NCBI Pathogen Isolates

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NCBI Reference Gene Catalog

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UniProt

Protein entries specific to Cj0843c

AMR Rules

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Validation StatusCandidate

Overview

Mechanism: beta-lactam resistance
Validation Method: mutant screening and complementation experiments
Drug Classes: ampicillin, penicillin, ticarcillin, carbenicillin, cloxacillin
Organisms: Campylobacter jejuni
Papers: 1
Databases: Reslit

Papers1

Important Role of a Putative Lytic Transglycosylase Cj0843c in β-Lactam Resistance in Campylobacter jejuni.

PMID 26635760 · 2015

Cj0843c, a putative lytic transglycosylase, is required for β-lactam resistance in Campylobacter jejuni. Inactivation of Cj0843c increases susceptibility to various β-lactam antibiotics, and its restoration through complementation restores resistance.

Gene Information

Gene Name: Cj0843c
Allele: Cj0843c
Encodes: putative lytic transglycosylase
Source Database: Reslit
Mechanism: beta-lactam resistance
Confers Resistance To: ampicillinpenicillinticarcillincarbenicillincloxacillin
Organisms Tested In: • Campylobacter jejuni
Validation Method: mutant screening and complementation experiments

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Cj0843c

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Cj0843c

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