CmlA2

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nonenzymatic chloramphenicol resistance protein

NCBI Pathogen Isolates

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NCBI Reference Gene Catalog

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UniProt

Protein entries specific to CmlA2

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Validation StatusConfirmed2+ DBs

Overview

Mechanism: Increased efflux
Validation Method: cloning in E. coli + MIC testing
Drug Classes: phenicols, CHLORAMPHENICOL
Organisms: Escherichia coli, Enterobacter aerogenes
Papers: 1
Databases: ResFinder DatabaseReslit

Papers1

Characterization of In40 of Enterobacter aerogenes BM2688, a class 1 integron with two new gene cassettes, cmlA2 and qacF.

PMID 9756755 · 1998

The study identifies two novel gene cassettes, qacF and cmlA2, within the class 1 integron In40 of Enterobacter aerogenes BM2688, which confer resistance to quaternary ammonium compounds and chloramphenicol, respectively.

Gene Information

Gene Name: CmlA2
Allele: CmlA2
Encodes: nonenzymatic chloramphenicol resistance protein
Source Database: Reslit
Confers Resistance To: phenicols
Organisms Tested In: • Escherichia coli
• Enterobacter aerogenes
Validation Method: cloning in E. coli + MIC testing
Sequence Accession: AF034958

Characterization of In40 of Enterobacter aerogenes BM2688, a class 1 integron with two new gene cassettes, cmlA2 and qacF.

PMID 9756755 · 1998

Gene Information

Gene Name: CmlA2
Allele: CmlA2
Source Database: ResFinder Database
Mechanism: Increased efflux
Confers Resistance To: CHLORAMPHENICOL
Sequence Accession: 47657

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CmlA2

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CmlA2

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