KPHS_p300880

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Dihydropteroate synthase

NCBI Pathogen Isolates

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UniProt

Protein entries specific to KPHS_p300880

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Validation StatusCandidate

Overview

Validation Method: up-regulation of gene expression
Drug Classes: trimethoprim sulfamethoxazole
Organisms: Klebsiella pneumoniae
Papers: 1
Databases: Reslit

Papers1

Transcriptomic analysis reveals pathways underlying the multi-antibiotic resistance of Klebsiella pneumoniae.

PMID 39688881 · 2025

The study identifies KPHS_p300670 and KPHS_p300880 as genes up-regulated in DY16KPN, contributing to resistance against trimethoprim/sulfamethoxazole by increasing the expression of dihydrofolate reductase and dihydropteroate synthase.

Gene Information

Gene Name: KPHS_p300880
Allele: KPHS_p300880
Encodes: Dihydropteroate synthase
Source Database: Reslit
Confers Resistance To: trimethoprim sulfamethoxazole
Organisms Tested In: • Klebsiella pneumoniae
Validation Method: up-regulation of gene expression

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KPHS_p300880

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KPHS_p300880

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