Browse AMR Genes

Explore antimicrobial resistance genes from the literature

PA1874

Hypothetical protein (efflux pump)

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to PA1874

Browse AMR rules for PA1874

Overview

Drug Classes: meropenem
Organisms: Pseudomonas aeruginosa
Papers: 1
Mutations: 4

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
-	A2G	-	Pseudomonas aeruginosa	meropenem	Reslit	Candidate
-	C2T	-	Pseudomonas aeruginosa	meropenem	Reslit	Candidate
-	G2A	-	Pseudomonas aeruginosa	meropenem	Reslit	Candidate
-	T2C	-	Pseudomonas aeruginosa	meropenem	Reslit	Candidate

Papers1

1

Combining antibiotics with antivirulence compounds can have synergistic effects and reverse selection for antibiotic resistance in Pseudomonas aeruginosa.

PMID 32810152 · 2020

Mutation Information

PA1874: c.A2G PA1874: c.C2T PA1874: c.G2A PA1874: c.T2C

Nucleotide Change: A2G, C2T, G2A, T2C
Organisms: Pseudomonas aeruginosa
Confers Resistance To: meropenem
Validation Method: whole-genome sequencing
Source Database: Reslit