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Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
Ethionamide resistant Rv0565c
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| Mtub_Rv0565_ETO | Card Database | 1 | - | Mycobacterium tuberculosis H37Rv | - | - | NC_000962.3 | NP_215079.1 |
| Rv0565c | Reslit | 1 | ethionamide, prothionamide | Mycobacterium tuberculosis +1 | - | 2019 | - | - |
Bacterial Genome-Wide Association Identifies Novel Factors That Contribute to Ethionamide and Prothionamide Susceptibility in Mycobacterium tuberculosis.
Rv0565c contributes significantly to prothionamide susceptibility, with overexpression reducing IC50 and deletion increasing growth advantage in the presence of prothionamide and ethionamide.
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