Rv1250

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efflux pump

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

UniProt

Protein entries specific to Rv1250

AMR Rules

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Validation StatusCandidate

Overview

Validation Method: real time expression analysis
Drug Classes: rifampicin
Organisms: Mycobacterium tuberculosis
Geographic Location: India
Papers: 1
Databases: Reslit

Papers1

Potential impact of efflux pump genes in mediating rifampicin resistance in clinical isolates of Mycobacterium tuberculosis from India.

PMID 31557231 · 2019

The study identified that the efflux pump genes mmpL5, Rv0194, and Rv1250 were upregulated in rifampicin-resistant Mycobacterium tuberculosis isolates, suggesting their potential role in mediating rifampicin resistance.

Gene Information

Gene Name: Rv1250
Allele: Rv1250
Encodes: efflux pump
Source Database: Reslit
Confers Resistance To: rifampicin
Organisms Tested In: • Mycobacterium tuberculosis
Geographic Location: India
Validation Method: real time expression analysis

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Rv1250

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Rv1250

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