Rv1273c

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efflux pump

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

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UniProt

Protein entries specific to Rv1273c

AMR Rules

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Validation StatusCandidate

Overview

Mechanism: resistance
Validation Method: whole genome sequencing and phenotypic testing
Drug Classes: bedaquiline
Organisms: Mycobacterium tuberculosis
Papers: 1
Databases: Reslit

Papers1

Variants associated with Bedaquiline (BDQ) resistance identified in Rv0678 and efflux pump genes in Mycobacterium tuberculosis isolates from BDQ naïve TB patients in Pakistan.

PMID 35209842 · 2022

Gene Information

Gene Name: Rv1273c
Allele: Rv1273c
Encodes: efflux pump
Source Database: Reslit
Mechanism: resistance
Confers Resistance To: bedaquiline
Organisms Tested In: • Mycobacterium tuberculosis
Validation Method: whole genome sequencing and phenotypic testing

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Rv1273c

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Rv1273c

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