Rv2752c

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metal beta-lactamase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

UniProt

Protein entries specific to Rv2752c

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Validation StatusCandidate

Overview

Validation Method: genome-wide association study
Drug Classes: isoniazid, rifampicin
Organisms: Mycobacterium tuberculosis
Geographic Location: Peru
Papers: 1
Databases: Reslit

Papers1

GWAS for quantitative resistance phenotypes in Mycobacterium tuberculosis reveals resistance genes and regulatory regions.

PMID 31086182 · 2019

The study identifies 12 genetic regions and one single nucleotide substitution associated with resistance in Mycobacterium tuberculosis, highlighting the role of non-canonical loci and promoter regions in antibiotic resistance.

Gene Information

Gene Name: Rv2752c
Allele: Rv2752c
Encodes: metal beta-lactamase
Source Database: Reslit
Confers Resistance To: isoniazidrifampicin
Organisms Tested In: • Mycobacterium tuberculosis
Geographic Location: Peru
Validation Method: genome-wide association study

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Rv2752c

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Rv2752c

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