Rv3041c

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hypothetical protein

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

UniProt

Protein entries specific to Rv3041c

AMR Rules

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Validation StatusCandidate

Overview

Mechanism: mutation in the gene leads to resistance to rifampicin
Validation Method: machine learning and structural analysis
Drug Classes: rifampicin
Organisms: Mycobacterium tuberculosis
Geographic Location: Belarus|South Africa|South Korea|India
Papers: 1
Databases: Reslit

Papers1

Machine learning and structural analysis of Mycobacterium tuberculosis pan-genome identifies genetic signatures of antibiotic resistance.

PMID 30333483 · 2018

The study identifies 33 known AMR genes and 24 new genetic signatures of AMR in Mycobacterium tuberculosis using machine learning and structural analysis. It also reveals 97 epistatic interactions across 10 resistance classes and provides mechanistic insights into the selection of these genes.

Gene Information

Gene Name: Rv3041c
Allele: Rv3041c
Encodes: hypothetical protein
Source Database: Reslit
Mechanism: mutation in the gene leads to resistance to rifampicin
Confers Resistance To: rifampicin
Organisms Tested In: • Mycobacterium tuberculosis
Geographic Location: Belarus|South Africa|South Korea|India
Validation Method: machine learning and structural analysis

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Rv3041c

Gene Information

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Rv3041c

Gene Information