Rv3094c

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hypothetical protein predicted to belong to the FAD-containing Acyl-CoA dehydrogenase (ACAD) superfamily and participate in oxidation-reduction reactions

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UniProt

Protein entries specific to Rv3094c

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Validation StatusCandidate

Overview

Validation Method: overexpression in M. tuberculosis H37Ra and MIC analysis
Drug Classes: ethionamide
Organisms: Mycobacterium tuberculosis
Papers: 1
Databases: Reslit

Papers1

Omics analysis of Mycobacterium tuberculosis isolates uncovers Rv3094c, an ethionamide metabolism-associated gene.

PMID 36750726 · 2023

The study identifies Rv3094c as a flavin-dependent monooxygenase involved in ethionamide metabolism, demonstrating its role in ethionamide sulfoxidation, which is critical for its activation.

Gene Information

Gene Name: Rv3094c
Allele: Rv3094c
Encodes: hypothetical protein predicted to belong to the FAD-containing Acyl-CoA dehydrogenase (ACAD) superfamily and participate in oxidation-reduction reactions
Source Database: Reslit
Confers Resistance To: ethionamide
Organisms Tested In: • Mycobacterium tuberculosis
Validation Method: overexpression in M. tuberculosis H37Ra and MIC analysis

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Rv3094c

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Rv3094c

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