Rv3131

View on PubMed

putative nitroreductase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

UniProt

Protein entries specific to Rv3131

AMR Rules

Browse AMR rules for Rv3131

Validation StatusCandidate

Overview

Mechanism: nitroreductase
Validation Method: biochemical assays
Drug Classes: metronidazole
Organisms: Mycobacterium tuberculosis
Papers: 1
Databases: Reslit

Papers1

Functions of nitroreductases in mycobacterial physiology and drug susceptibility.

PMID 39772630 · 2025

The paper reviews the functions of various mycobacterial nitroreductases, highlighting their roles in drug activation, oxidative stress resistance, and cell envelope biosynthesis.

Gene Information

Gene Name: Rv3131
Allele: RV3131
Encodes: putative nitroreductase
Source Database: Reslit
Mechanism: nitroreductase
Confers Resistance To: metronidazole
Organisms Tested In: • Mycobacterium tuberculosis
Validation Method: biochemical assays

Comments (0)

No comments yet. Be the first to comment!

Rv3131

Gene Information

Browse AMR Genes

Rv3131

Gene Information