Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
inner membrane transporter
Overview
| Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|
| F136A | - | - | - | tigecycline | Reslit | Candidate |
| F608A | - | - | - | tigecycline | Reslit | Candidate |
| F613A | - | - | - | tigecycline | Reslit | Candidate |
| F615A | - | - | - | tigecycline | Reslit | Candidate |
| I624A | - | - | - | tigecycline | Reslit | Candidate |
| I139A | - | - | - | tigecycline | Reslit | Candidate |
| F626A | - | - | - | tigecycline | Reslit | Candidate |
| Y329A | - | - | - | tigecycline | Reslit | Candidate |
| F279A | - | - | - | tigecycline | Reslit | Candidate |
| V610A | - | - | - | tigecycline | Reslit | Candidate |
| G135V | - | - | Klebsiella pneumoniae | tigecycline | Reslit | Candidate |
Assembly and inhibition of transferable TMexCD1-TOprJ1 efflux pump.
Mutations in TMexD1 affect tigecycline resistance.
Repurposing harmaline as a novel approach to reverse tmexCD1-toprJ1-mediated tigecycline resistance against klebsiella pneumoniae infections.