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Browse GenesTOprJ3

TOprJ3

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to TOprJ3

Browse AMR rules for TOprJ3

Validation StatusEstablished

Overview

Mechanism: Efflux pump
Drug Classes: MINOCYCLINE, TETRACYCLINE, TIGECYCLINE, DOXYCYCLINE
Organisms: Klebsiella aerogenes
Papers: 1
Databases: ResFinder Database

Papers1

1

A Transferable IncC-IncX3 Hybrid Plasmid Cocarrying bla(NDM-4), tet(X), and tmexCD3-toprJ3 Confers Resistance to Carbapenem and Tigecycline.

PMID 34346701 · 2021

Gene Information

Gene Name: TOprJ3
Allele: TOprJ3
Source Database: ResFinder Database
Mechanism: Efflux pump
Confers Resistance To: MINOCYCLINETETRACYCLINETIGECYCLINEDOXYCYCLINE
Organisms Tested In: • Klebsiella aerogenes
Sequence Accession: LC633285
Notes: Together with tmexC3 and tmexD3

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research