Tet38

efflux pump

Overview

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
R106C	-	-	-	tetracycline\|minocycline\|fosfomycin	Reslit	Candidate
G151C	-	-	-	tetracycline\|fosfomycin	Reslit	Candidate

Papers1

Staphylococcus aureus Tet38 Efflux Pump Structural Modeling and Roles of Essential Residues in Drug Efflux and Host Cell Internalization.

Mutations in Tet38 affect drug efflux and host cell internalization.

Protein Change: R106C, G151C
Confers Resistance To: tetracycline|minocycline|fosfomycintetracycline|fosfomycin
Validation Method: MIC testing and internalization assays
Source Database: Reslit