aaa25

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aminoglycoside acetyltransferase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

UniProt

Protein entries specific to aaa25

AMR Rules

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Validation StatusCandidate

Overview

Validation Method: gene characterization in ICE
Drug Classes: gentamicin, kanamycin, tobramycin
Organisms: Mannheimia haemolytica
Geographic Location: Texas|Nebraska|Alberta|France|Alberta, Canada|Nebraska, Texas, USA|Nantes, France
Papers: 1
Databases: Reslit

Papers1

Comparative Genomic Analysis of Mannheimia haemolytica from Bovine Sources.

PMID 26926339 · 2016

The study identified a bla ROB-1 gene in an integrative conjugative element (ICE) of M. haemolytica, which had a single nucleotide substitution leading to a non-functional gene and sensitivity to ampicillin.

Gene Information

Gene Name: aaa25
Allele: aaA25
Encodes: aminoglycoside acetyltransferase
Source Database: Reslit
Confers Resistance To: gentamicinkanamycintobramycin
Organisms Tested In: • Mannheimia haemolytica
Geographic Location: Texas|Nebraska|Alberta|France|Alberta, Canada|Nebraska, Texas, USA|Nantes, France
Validation Method: gene characterization in ICE
Sequence Accession: LFXX00000000|LFXY00000000|LFYD00000000|LFYB00000000|LFXW00000000|LFXZ00000000|LFYC00000000|LFYA00000000|LFXV00000000|AOGP00000000|LFYE00000000|CP005383|NC_021082

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aaa25

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aaa25

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