Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
aminoglycoside N-acetyltransferase AAC(3)-Id
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| AAC(3)-Id | Card DatabaseReference Gene CatalogReslit | 28 | GENTAMICIN, gentamicin +5 | Pseudomonas aeruginosa +11 | France, United Kingdom, USA|Peru|Egypt|Cambodia|Kenya, Nigeria, Europe|Poland, Canada, Saudi Arabia, China|Bangladesh|USA|England|India, Senegal, Ethiopia|Kenya, Switzerland, Singapore, Bangladesh, Greece, China, Egypt, Kenya, Thailand, Harare, Zimbabwe, Europe, Algeria | 2004, 2006, 2018, 2020, 2021, 2022, 2023, 2024, 2025 | AM749810.1 | CAO78542.1 |
| aac(3)-Id | ResFinder Database | 1 | ASTROMICIN, FORTIMICIN +1 | Vibrio fluvialis | - | 2004 | AB114632 | - |
| aac3-Id | Reslit | 1 | gentamicin | Salmonella enteritidis +5 | Shandong province, China | 2019 | - | - |
| aac (3)-Id | Reslit | 1 | aminoglycosides | Pseudomonas aeruginosa | Pakistan | 2021 | JADDMB000000000|JADDMA000000000|JADEYD000000000|JADDLZ000000000|JADDLY000000000|JADDLX000000000|PRJNA669539|PRJNA670459 | - |
New aminoglycoside acetyltransferase gene, aac(3)-Id, in a class 1 integron from a multiresistant strain of Vibrio fluvialis isolated from an infant aged 6 months.
New aminoglycoside acetyltransferase gene, aac(3)-Id, in a class 1 integron from a multiresistant strain of Vibrio fluvialis isolated from an infant aged 6 months.
New aminoglycoside acetyltransferase gene, aac(3)-Id, in a class 1 integron from a multiresistant strain of Vibrio fluvialis isolated from an infant aged 6 months.
Variant Salmonella genomic island 1 antibiotic resistance gene cluster containing a novel 3′-N-aminoglycoside acetyltransferase gene cassette, aac(3)-Id, in Salmonella enterica serovar newport.
The study identifies a novel 3'-N-aminoglycoside acetyltransferase gene, aac(3)-Id, which confers resistance to gentamicin and sisomicin in Salmonella enterica serovar Newport.
Mechanism of drug resistance in clonally related clinical isolates of Vibrio fluvialis isolated in Kolkata, India.
Prediction of Phenotypic Antimicrobial Resistance Profiles From Whole Genome Sequences of Non-typhoidal Salmonella enterica.
The study identified various AMR genes and mutations in non-typhoidal Salmonella enterica, including blaTEM-1, strA-strB, sul2, tet(A), qnrS1, aadA2, aadA17, floR, cmlA1, aac(3)-Id, aac(3)-IIa, dfrA12, dfrA1, dfrA14, blaCTX-M-9, blaCTX-M-55, blaSHV-12, blaPSE-1/blaCARB-2, and blaCMY-2, along with mutations in gyrA and parC associated with ciprofloxacin resistance.
Serotype, antimicrobial susceptibility and genotype profiles of Salmonella isolated from duck farms and a slaughterhouse in Shandong province, China.
The study identified multiple antimicrobial resistance genes, including blaTEM, sul2, aadA7, aac3-Id, aadA5, and dfrA17, in Salmonella isolates from duck farms and a slaughterhouse in Shandong, China. High levels of resistance to various antibiotics were observed, highlighting the need for improved antimicrobial stewardship.
Tracking Antimicrobial Resistance Determinants in Diarrheal Pathogens: A Cross-Institutional Pilot Study.
The study identified 55 different antimicrobial resistance determinants in diarrheal pathogens, highlighting the presence of genes conferring resistance to multiple antibiotic classes, including beta-lactams, aminoglycosides, macrolides, tetracyclines, phenicols, sulfonamides, and others. Notably, carbapenemase genes like bla OXA-48 and bla NDM were detected in certain isolates, indicating emerging resistance concerns.
A Biological Inventory of Prophages in A. baumannii Genomes Reveal Distinct Distributions in Classes, Length, and Genomic Positions.
The study identifies several antimicrobial resistance (AMR) genes encoded in prophages within Acinetobacter baumannii genomes, including blaOXA-23, blaNDM-1, blaADC-5, blaOXA-67, blaOXA-115, blaTEM-12, aac(3)-I, aac(3)-Id, aacA16, aph(3')-Ia, aph(3')-VI, aph(6)-Id, aph(3'')-Ib, msr(E), mph(E), and sul2. These genes confer resistance to various antibiotics such as carbapenems, penicillins, cephalosporins, monobactams, aminoglycosides, macrolides, and sulfonamides.
Genomic Analysis of Antimicrobial Resistance and Resistance Plasmids in Salmonella Serovars from Poultry in Nigeria.
The study identified various antimicrobial resistance genes in Salmonella isolates from Nigerian poultry, including aac(6')-Ia, aac(6')-Ib, aadA7, aph(3")-Ia, aph(3")-Ib, aph(6')-Id, aph(6')-Ic, aac(3)-Ia, aac(3)-IIa, aac(3)-IVa, aac(6')-IIa, aac(3)-Id, sul1, sul2, sul3, tet(A), tet(M), qnrS1, qnrB19, blaTEM, dfrA14, dfrA15, dfrA17, catA1, cmlA1, and floR. Mutations in gyrA (Ser83Phe, Asp87Tyr) and parC (Thr57Ser, Ser80Ile) were also associated with resistance to nalidixic acid and ciprofloxacin.
Antimicrobial Resistance and Whole-Genome Characterisation of High-Level Ciprofloxacin-Resistant Salmonella Enterica Serovar Kentucky ST 198 Strains Isolated from Human in Poland.
The study identified several AMR genes and mutations in high-level ciprofloxacin-resistant Salmonella Enterica serovar Kentucky ST198 strains isolated from humans in Poland, including blaTEM-1B, qnrS1, aac(3)-Id, aac(3)-IId, aac(6')-Iaa, aac(6')-Iid, aph(3")-Ib, aph(3")-Id, aadA1, sul1, dfrA1, and tetA, along with mutations in gyrA and parC that confer resistance to quinolones and beta-lactams.
A One-Health Genomic Investigation of Gentamicin Resistance in Salmonella from Human and Chicken Sources in Canada, 2014 to 2017.
The study identified several aminoglycoside-modifying enzymes, including aac(3)-VIa, aac(3)-IId, aac(3)-Id, aac(3)-IVa, aac(3)-IIa, ant(2′′)-Ia, aac(6′)-Ib-cr, aadA2, aadA7, aadA1, ant(3′′)-Ia, aac(6′)-Ib3, and rmtB, as key contributors to gentamicin resistance in Salmonella isolates from both human and chicken sources in Canada.
Antimicrobial Resistance and Genomic Characterization of Six New Sequence Types in Multidrug-Resistant Pseudomonas aeruginosa Clinical Isolates from Pakistan.
The study identified 13 acquired antibiotic resistance genes in six new sequence types of multidrug-resistant Pseudomonas aeruginosa isolates from Pakistan, including beta-lactamases, aminoglycoside-modifying enzymes, and others. Mutations in the pmrA gene were also found to contribute to colistin resistance.
Genomic Characterization of Carbapenem-Non-susceptible Pseudomonas aeruginosa Clinical Isolates From Saudi Arabia Revealed a Global Dissemination of GES-5-Producing ST235 and VIM-2-Producing ST233 Sub-Lineages.
The study identified GES-5-producing ST235 and VIM-2-producing ST233 sub-lineages of Pseudomonas aeruginosa in Saudi Arabia, highlighting their global dissemination and the presence of various resistance genes including blaGES-5, blaVIM-2, and others.
Population genomics of the food-borne pathogen Vibrio fluvialis reveals lineage associated pathogenicity-related genetic elements.
The study identified 21 antimicrobial resistance genes in Vibrio fluvialis, with 19 of them predominantly present in VflPop2. The tetracycline resistance gene tet(35) was found in 95% of VflPop2 strains, highlighting its significance in the population. Additionally, the plasmid pBD146 was associated with resistance to trimethoprim-sulfamethoxazole, and the presence of dfr6 gene in pBD146 was linked to this resistance.
Genomics of human and chicken Salmonella isolates in Senegal: Broilers as a source of antimicrobial resistance and potentially invasive nontyphoidal salmonellosis infections.
The study identified multiple antimicrobial resistance genes and mutations in Salmonella isolates from Senegal, highlighting the prevalence of resistance to fluoroquinolones, sulfamethoxazole-trimethoprim, tetracycline, and erythromycin. Key genes included aac(3)-Id, aadA7, blaTEM-1b, blaDHA-1, blaOXA-10, blaCMY-2, dfrA1, dfrA14, floR, fosA, qnrB19, qnrB7, sul2, tetA, tetB, aph(3')-Ib, aph(3")-Ib, and aph(6)-Id. Mutations in parC and gyrA were also associated with fluoroquinolone resistance.
Genomic and Evolutionary Analysis of Salmonella enterica Serovar Kentucky Sequence Type 198 Isolated From Livestock In East Africa.
The study identified multiple antimicrobial resistance genes in Salmonella enterica serovar Kentucky ST198 isolates from East Africa, including aac(3)-Id, aadA7, strA, strB, bla TEM-1B, sul1, and tet(A), which confer resistance to aminoglycosides, streptomycin, ampicillin, sulfamethoxazole, and tetracycline. Mutations in gyrA and parC were associated with ciprofloxacin resistance.
Epidemiological links and antimicrobial resistance of clinical Salmonella enterica ST198 isolates: a nationwide microbial population genomic study in Switzerland.
The study identifies several AMR genes and mutations associated with ciprofloxacin resistance in Salmonella enterica ST198 isolates, including aac(3)-Id, aadA7, bla TEM-1b, sul1, tetA, qnrB1, qnrS1, bla CTX-M-14b, bla VEB-8, and bla OXA-48. Additionally, inactivating mutations in ramR and acrB were found to contribute to high-level ciprofloxacin resistance.
Dissemination of Pseudomonas aeruginosa bla(NDM-1)-Positive ST308 Clone in Singapore.
The study identifies multiple antibiotic resistance genes (ARGs) in bla NDM-1 -positive P. aeruginosa ST308 isolates, including aac(3)-Id, aac(6′)-Il, aph(3′)-Iib, bla OXA-488, bla NDM-1, bla PDC-19a, catB7, crpP, fosA, msr(E), qnrVC1, sul2, dfrB5, floR, aadA6, aadA11, and aph(3″)-Ib. These genes confer resistance to various antibiotics such as aminoglycosides, beta-lactams, carbapenems, cephalosporins, chloramphenicol, fluoroquinolones, fosfomycin, macrolides, quinolones, sulfonamides, trimethoprim, and streptomycin.
Antimicrobial resistance and genomic characterization of Salmonella enterica isolates from chicken meat.
The study identified multiple antimicrobial resistance genes in Salmonella enterica isolates from chicken meat, including aminoglycoside, beta-lactam, quinolone, tetracycline, sulfonamide, and phenicol resistance genes. These genes were detected using whole genome sequencing and correlated with phenotypic resistance profiles.
Multidrug-resistant non-typhoidal Salmonella of public health significance recovered from migratory birds in Bangladesh.
The study identified multidrug-resistant non-typhoidal Salmonella in migratory birds in Bangladesh, highlighting the presence of various AMR genes such as blaCARB-2, floR, sul1, tet(G), dfrA1, and mutations in gyrA and parC associated with quinolone resistance.
First Detection and Molecular Characterization of Pseudomonas aeruginosa bla(NDM-1) ST308 in Greece.
The study reports the first detection of blaNDM-1-positive Pseudomonas aeruginosa ST308 in Greece, highlighting the presence of multiple resistance genes including blaNDM-1, blaPAO, blaOXA-10, blaOXA-488, and others, indicating multidrug resistance.
Persistent Colonization of Ciprofloxacin-Resistant and Extended-Spectrum β-Lactamase (ESBL)-Producing Salmonella enterica Serovar Kentucky ST198 in a Patient with Inflammatory Bowel Disease.
The study characterizes three ciprofloxacin-resistant and extended-spectrum β-lactamase (ESBL)-producing Salmonella enterica serovar Kentucky ST198 strains from a single patient with inflammatory bowel disease, highlighting their multidrug-resistant profile and potential epidemiological links to strains from chicken meat.
Genomic profiling of pan-drug resistant proteus mirabilis Isolates reveals antimicrobial resistance and virulence gene landscape.
The study identified multiple antimicrobial resistance genes in pan-drug resistant Proteus mirabilis isolates, including genes conferring resistance to aminoglycosides, beta-lactams, tetracyclines, sulfonamides, and others. These genes were found on the chromosome and contributed to the isolates' resistance to various antibiotic classes.
Molecular characterization of multidrug-resistant E. coli recovered from diarrheagenic children under 5 years from Mukuru Informal Settlement, Nairobi, Kenya, based on whole-genome sequencing analysis.
The study identified multiple AMR genes and mutations in multidrug-resistant E. coli isolates from diarrheagenic children in Nairobi, Kenya, highlighting the presence of blaTEM-1B, blaCTX-M-15, qnrS1, qnrB4, aac(6')-Ib-cr, and other resistance mechanisms.
Unveiling the Genetic Diversity and Antimicrobial Resistance Profiles of Salmonella Population From 2016 to 2020 in Thai Canal Water.
The study identified 50 acquired resistance genes and seven chromosomal-mediated gene mutations in Salmonella populations from Thai canal water, highlighting the prevalence of multidrug-resistant strains and the diversity of resistance mechanisms.
Genetic diversity and antimicrobial resistance profiles of Salmonella enterica in the broiler supply chain in Harare, Zimbabwe: tracking transmission from farm to table.
The study identified several AMR genes and mutations in Salmonella enterica isolates from the broiler supply chain in Zimbabwe, including fosA7.2, qnrB19, aadA1, aph(3'')-Ib, aph(6)-Id, aac(3)-Id, fosA3, sul1, sul3, tetA, cmlA1, blaCMY-2, blaTEM-1B, blaCTX-M-14, and mutations in gyrA and parC. These genes and mutations confer resistance to various antibiotics, including fosfomycin, fluoroquinolones, aminoglycosides, sulfonamides, tetracyclines, chloramphenicol, and beta-lactams.
Genetic and virulence factors behind the success of high-risk Pseudomonas aeruginosa clones: insights from comparative genomics and an experimental infection model.
The study identified 15 AMR genes significantly more frequent in high-risk P. aeruginosa clones, including aminoglycoside, beta-lactam, phenicol, fluoroquinolone, trimethoprim, sulfonamide, and tetracycline resistance genes. These genes are often associated with mobile genetic elements, indicating a mobility-linked resistome in high-risk clones.
Genomic characterisation of multidrug-resistant Salmonella enterica serovar Kentucky ST198 isolates from various sources in Algeria, North Africa.
The study identified multiple AMR genes and chromosomal mutations in multidrug-resistant Salmonella enterica serovar Kentucky ST198 isolates from Algeria, including bla TEM-1B, bla CTX-M-15, aac(3)-Id, aadA7, sul1, tet(A), mph(A), qnrB19, cmlA1, and floR, along with mutations in gyrA and parC genes that confer resistance to ciprofloxacin.
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