aac(4)-iia

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aminoglycoside modifying enzyme

NCBI Pathogen Isolates

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NCBI Reference Gene Catalog

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UniProt

Protein entries specific to aac(4)-iia

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Validation StatusCandidate

Overview

Mechanism: modifies aminoglycosides
Validation Method: whole genome sequencing and ResFinder
Drug Classes: streptomycin
Organisms: Salmonella enterica subsp. enterica
Geographic Location: China
Papers: 1
Databases: Reslit

Papers1

Genomic and virulent characterization of a duck-associated Salmonella serovar Potsdam from China.

PMID 39693960 · 2025

The study identified several antimicrobial resistance genes and mutations in Salmonella serovar Potsdam isolated from duck embryos, including aac(3')-Ia, aac(4')-IIa, aph(3')-IIa, aph(3')'-Ib, aph(6')-Id, blaTEM-116, blaTEM-1B, and tet(A), as well as gyrA and parC mutations associated with quinolone resistance.

Gene Information

Gene Name: aac(4)-iia
Allele: aac(4')-IIa
Encodes: aminoglycoside modifying enzyme
Source Database: Reslit
Mechanism: modifies aminoglycosides
Confers Resistance To: streptomycin
Organisms Tested In: • Salmonella enterica subsp. enterica
Geographic Location: China
Validation Method: whole genome sequencing and ResFinder
Sequence Accession: PRJNA1007938|SAMN17221882

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aac(4)-iia

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aac(4)-iia

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