Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
aminoglycoside 6'-N-acetyltransferase AAC(6')-Ia
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| AAC(6')-Ia | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 15 | AMINOGLYCOSIDE, TOBRAMYCIN +9 | Enterobacter hormaechei subsp. hoffmannii +13 | India, Mexico, Serbia, Nigeria, Tokyo, Japan|Japan, Germany|Colombia|Vietnam|Japan|Nicaragua|United States|Canada|Brazil|Thailand|Lebanon|Poland|France|Italy|Spain|Portugal|Mexico|China|South Korea|India, China|United States|United Kingdom|Canada|Germany|Brazil|Australia, Thailand, Guangdong, China | 2001, 2019, 2020, 2021, 2022, 2024, 2025 | LPQV01000084.1 | KTK23273.1 |
| aac(6')-Ia | ResFinder Database | 1 | TOBRAMYCIN, AMIKACIN +3 | Plasmid R, Shigella sonnei | - | 1988 | M18967, M86913 | - |
| aac6'Ia | Reslit | 1 | gentamicin, kanamycin +1 | Salmonella enterica subsp. enterica serovar Typhi | Pakistan | 2025 | NCBI:CP079815|NCBI:CP079816|NCBI:CP079817|NCBI:CP079818|NCBI:CP079819|NCBI:CP079820|NCBI:CP079821|NCBI:CP079822|NCBI:CP079823|NCBI:CP079824|NCBI:CP079825|NCBI:CP079826|NCBI:CP079827|NCBI:CP079828|NCBI:CP079829|NCBI:CP079830|NCBI:CP079831|NCBI:CP079832|NCBI:CP079833|NCBI:CP079834|NCBI:CP079835|NCBI:CP079836|NCBI:CP079837|NCBI:CP079838|NCBI:CP079839|NCBI:CP079840|NCBI:CP079841|NCBI:CP079842|NCBI:CP079843 | - |
Characterization of In53, a class 1 plasmid- and composite transposon-located integron of Escherichia coli which carries an unusual array of gene cassettes.
Cloning and sequencing of a gene encoding an aminoglycoside 6'-N-acetyltransferase from an R factor of Citrobacter diversus., Functional and physiological characterization of the Tn21 cassette for resistance genes in Tn2426.
Extensive drug resistant Salmonella enterica serovar Senftenberg carrying blaNDM encoding plasmid p5558 (IncA/C) from India.
The study identifies multiple antimicrobial resistance genes in a multidrug-resistant Salmonella enterica serovar Senftenberg isolate, including blaNDM-1, blaTEM-1, blaOXA-9, blaCMY-2, aac(6')-Ia, aac(6')-Ib, aph(3')-Ib, aph(6')-Ib, ant(3'')-Ia, sul-1, sul-2, and florR. Additionally, mutations in gyrA (S83Y, D87G) and parC (S80I) were associated with fluoroquinolone resistance.
Whole-Genome Sequences of Five Acinetobacter baumannii Strains From a Child With Leukemia M2.
Five multidrug-resistant Acinetobacter baumannii strains from a child with leukemia M2 were characterized. They harbored blaOXA-51 and blaOXA-23 genes, which confer resistance to carbapenems.
Genomic Characteristics of Colistin-Resistant Salmonella enterica subsp. enterica Serovar Infantis from Poultry Farms in the Republic of Serbia.
The study identified the fosfomycin resistance gene fosA7 and the vgaA gene in Salmonella enterica subsp. enterica serovar Infantis isolates from poultry farms in Serbia. Mutations in the pmrB gene were associated with colistin resistance.
Genomic Analysis of Antimicrobial Resistance and Resistance Plasmids in Salmonella Serovars from Poultry in Nigeria.
The study identified various antimicrobial resistance genes in Salmonella isolates from Nigerian poultry, including aac(6')-Ia, aac(6')-Ib, aadA7, aph(3")-Ia, aph(3")-Ib, aph(6')-Id, aph(6')-Ic, aac(3)-Ia, aac(3)-IIa, aac(3)-IVa, aac(6')-IIa, aac(3)-Id, sul1, sul2, sul3, tet(A), tet(M), qnrS1, qnrB19, blaTEM, dfrA14, dfrA15, dfrA17, catA1, cmlA1, and floR. Mutations in gyrA (Ser83Phe, Asp87Tyr) and parC (Thr57Ser, Ser80Ile) were also associated with resistance to nalidixic acid and ciprofloxacin.
Institutional outbreak involving multiple clades of IMP-producing Enterobacter cloacae complex sequence type 78 at a cancer center in Tokyo, Japan.
The study identified multiple clades of IMP-producing Enterobacter cloacae complex sequence type 78 (ST78) strains causing an institutional outbreak. These strains carried blaIMP-1 and blaIMP-11 genes on IncHI2 and IncL/M plasmids, along with various other resistance genes such as aac(6')-IIc, qnrB6, fosA, sul1, and tet(B).
Antimicrobial Resistance in Acinetobacter spp. Isolated from Pet Reptiles
The study identified various AMR genes in Acinetobacter spp. isolated from pet reptiles, including tetracycline, sulfonamide, and aminoglycoside resistance genes, highlighting the presence of multidrug-resistant strains in these animals.
Contribution of the Mobilome to the Configuration of the Resistome of Corynebacterium striatum.
The study identified 20 antimicrobial resistance genes in Corynebacterium striatum, with ErmX being the most prevalent. These genes are mainly associated with plasmid sequence regions and class 1 integrons, highlighting the role of mobile genetic elements in the dissemination of resistance.
Retrospective analysis of antimicrobial resistance of Salmonella spp. isolated from livestock and its environment in Thailand.
The study identified several AMR genes in Salmonella isolates from livestock and their environment in Thailand, including aadA1, aadA2, aadB, aac(6')-Ia, blaTEM, tetA, tetB, catA, catB, cmlA, sulI, and dfrA1, which confer resistance to various antibiotics such as aminoglycosides, beta-lactams, tetracyclines, chloramphenicol, sulfamethoxazole, and trimethoprim.
Antimicrobial Resistance of Salmonella and Characterization of Two Mcr-1-Harboring Isolates from Pork Products in Guangdong, China.
Two mcr-1-harboring Salmonella Kentucky ST198 isolates were identified, showing resistance to multiple antibiotics including colistin, tetracycline, and fluoroquinolones. The study highlights the presence of complex resistance determinants such as the multidrug resistance region (MRR) and SGI1-KI.
Whole-Genome Sequencing Analysis of Drug-Resistant Salmonella Typhi in Children.
The study identified several AMR genes and mutations in drug-resistant Salmonella Typhi isolates from children, including bla_CTXM15, bla_TEM1B, qnrS1, aac6'Ia, catA1, dfrA7, sul1, qacEΔ1, and the gyrA_S83F mutation, which are associated with resistance to various antibiotics such as ciprofloxacin, ampicillin, chloramphenicol, and sulfamethoxazole.
Genetic insights into antimicrobial resistance and virulence characteristics of Salmonella enterica isolated from Nile tilapia sourced from retail markets in Thailand.
The study identified multiple antimicrobial resistance (AMR) genes in Salmonella enterica isolates from Nile tilapia, including beta-lactamases (bla TEM−1B, bla CTX−M−55, bla CTX−M−14, bla LAP−2), quinolone resistance genes (qnrS1, qnrS13), tetracycline resistance genes (tet(A), tet(B), tet(M)), aminoglycoside resistance genes (aadA2, aph(3’’)-Ib, aph(6)-Id, aac(6’)-Ia), sulfonamide resistance genes (sul1, sul2, sul3), florfenicol resistance gene (floR), and efflux pump systems (mdsABC, mdtK).
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