Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
aminoglycoside N-acetyltransferase AAC(6')-Iz
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| AAC(6')-Iz | Card DatabaseReference Gene CatalogReslit | 10 | TOBRAMYCIN, aminoglycosides | Stenotrophomonas maltophilia EPM1 +2 | Taiwan|North America|South America|Europe|Asia|Australia | 1999, 2008, 2023, 2024, 2025 | AMXM01000008.1 | EMF61681.1 |
| aac(6')-Iz | ResFinder Database | 1 | TOBRAMYCIN, AMIKACIN | Stenotrophomonas maltophilia, Stenotrophomonas maltophilia K279a | - | 1999 | AF140221, AB971834 | - |
Characterization of the chromosomal aac(6')-Iz gene of Stenotrophomonas maltophilia.
Characterization of the chromosomal aac(6')-Iz gene of Stenotrophomonas maltophilia.
Characterization of the chromosomal aac(6')-Iz gene of Stenotrophomonas maltophilia., The complete genome, comparative and functional analysis of Stenotrophomonas maltophilia reveals an organism heavily shielded by drug resistance determinants.
The complete genome, comparative and functional analysis of Stenotrophomonas maltophilia reveals an organism heavily shielded by drug resistance determinants.
Antimicrobial Resistance in Stenotrophomonas maltophilia: Mechanisms, Clinical Implications, and Potential Therapeutic Strategies
The paper discusses the multidrug-resistant nature of Stenotrophomonas maltophilia, highlighting its resistance to various antibiotics including β-lactams, fluoroquinolones, aminoglycosides, and polymyxins. It emphasizes the challenges in treating infections caused by this pathogen due to its intrinsic resistance mechanisms and the need for alternative therapeutic approaches.
Acquired resistance of Stenotrophomonas maltophilia to antimicrobials induced by herbicide paraquat dichloride.
Exposure of Stenotrophomonas maltophilia to paraquat induces multidrug resistance through genetic mutations affecting efflux pumps, ribosomal proteins, and metabolic enzymes.
Genomic analysis of contaminant Stenotrophomonas maltophilia, from placental swab culture, carrying antibiotic resistance: a potential hospital laboratory contaminant.
The study identified six antibiotic resistance genes in Stenotrophomonas maltophilia RAOG732, including aac(6')-Iz, aac(6')-Ib7, aph(3')-IIc, oqxB, sul1, and blaL1, which conferred resistance to aminoglycosides, fluoroquinolones, folate synthesis inhibitors, and beta-lactams.
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