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Browse Genesaac(6)-le-aph(2)-la

aac(6)-le-aph(2)-la

aminoglycoside modifying enzyme

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to aac(6)-le-aph(2)-la

Browse AMR rules for aac(6)-le-aph(2)-la

Validation StatusCandidate

Overview

Validation Method: genomic analysis and MIC testing
Drug Classes: gentamicin
Organisms: Staphylococcus epidermidis, Staphylococcus saprophyticus, Staphylococcus hominis, Staphylococcus warneri, Staphylococcus haemolyticus
Papers: 1
Databases: Reslit

Papers1

1

Known mechanisms cannot account for a third of reduced susceptibility in non-aureus staphylococci.

PMID 39843942 · 2023

Gene Information

Gene Name: aac(6)-le-aph(2)-la
Allele: aac(6')-le-aph(2")-la
Encodes: aminoglycoside modifying enzyme
Source Database: Reslit
Confers Resistance To: gentamicin
Organisms Tested In: • Staphylococcus epidermidis
• Staphylococcus saprophyticus
• Staphylococcus hominis
• Staphylococcus warneri
• Staphylococcus haemolyticus
Validation Method: genomic analysis and MIC testing

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research