aac(6)ib4

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aminoglycoside acetyltransferase

NCBI Pathogen Isolates

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NCBI Reference Gene Catalog

Known alleles and reference sequences

UniProt

Protein entries specific to aac(6)ib4

AMR Rules

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Validation StatusCandidate

Overview

Validation Method: genomic analysis
Drug Classes: amikacin, gentamicin, tobramycin
Organisms: Pseudomonas aeruginosa
Geographic Location: clinical|environmental
Papers: 1
Databases: Reslit

Papers1

Variation in the response to antibiotics and life-history across the major Pseudomonas aeruginosa clone type (mPact) panel.

PMID 38860784 · 2024

The study identifies variations in antibiotic resistance and life-history traits among the mPact panel of Pseudomonas aeruginosa strains, highlighting the presence of specific AMR genes and mutations contributing to resistance against various antibiotics.

Gene Information

Gene Name: aac(6)ib4
Allele: aac(6')Ib4
Encodes: aminoglycoside acetyltransferase
Source Database: Reslit
Confers Resistance To: amikacingentamicintobramycin
Organisms Tested In: • Pseudomonas aeruginosa
Geographic Location: clinical|environmental
Validation Method: genomic analysis
Sequence Accession: GCF_900185255.1|GCF_022570475.1|GCF_022570455.1|GCF_022570435.1|GCF_022570415.1|GCF_022570395.1|GCF_022570235.1|GCF_022570115.1|GCF_022569995.1|GCF_022569975.1|GCF_022569955.1|SAMEA2472080|GCF_022488025.1|GCF_022487965.1|GCF_022569935.1|GCF_022569915.1|GCF_022569895.1|GCF_022487975.1|GCF_022569875.1|GCF_022569855.1|GCA_000006765.1|GCF_000014625.1

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aac(6)ib4

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aac(6)ib4

Gene Information