aac(6)ie-aph(2″)ia

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aminoglycoside acetyltransferase

NCBI Pathogen Isolates

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NCBI Reference Gene Catalog

Known alleles and reference sequences

UniProt

Protein entries specific to aac(6)ie-aph(2″)ia

AMR Rules

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Validation StatusCandidate

Overview

Mechanism: Antibiotic inactivation enzyme
Validation Method: Genome analysis
Drug Classes: gentamicin
Organisms: Staphylococcus aureus
Geographic Location: Malaysia
Papers: 1
Databases: Reslit

Papers1

Complete Genome Sequence and Analysis of a ST573 Multidrug-Resistant Methicillin-Resistant Staphylococcus aureus SauR3 Clinical Isolate from Terengganu, Malaysia.

PMID 36986424 · 2023

The study identifies multiple antimicrobial resistance genes in the multidrug-resistant S. aureus isolate SauR3, including blaZ, mecA, norA, norC, sdrM, ermC, lmrS, msrA, mphC, aph(3′)-IIIa, aadE, aac(6′)Ie-aph(2″)Ia, fosB, and SAT-4, contributing to resistance against various antibiotics.

Gene Information

Gene Name: aac(6)ie-aph(2″)ia
Allele: aac(6′)Ie-aph(2″)Ia
Encodes: aminoglycoside acetyltransferase
Source Database: Reslit
Mechanism: Antibiotic inactivation enzyme
Confers Resistance To: gentamicin
Organisms Tested In: • Staphylococcus aureus
Geographic Location: Malaysia
Validation Method: Genome analysis
Sequence Accession: CP098727|CP098728|CP098730|CP014405|AP003089|AP014922

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aac(6)ie-aph(2″)ia

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aac(6)ie-aph(2″)ia

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