Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
aminoglycoside acetyltransferase
Overview
Genotypes, exotoxin gene content, and antimicrobial resistance of Staphylococcus aureus strains recovered from foods and food handlers.
The study identified various AMR genes in S. aureus strains from foods and food handlers, including blaZ, mupA, ermC, msrB, msrA, aacA, aphD, aadD, and tetK, which confer resistance to beta-lactams, mupirocin, erythromycin, clindamycin, aminoglycosides, and tetracycline.
Transcriptome mapping of pAR060302, a blaCMY-2-positive broad-host-range IncA/C plasmid.
The study characterizes the transcriptome of pAR060302, a blaCMY-2-positive IncA/C plasmid, highlighting the transcription of resistance genes such as blaCMY-2, aadA, aacA, and floR, which confer resistance to extended-spectrum cephalosporins, aminoglycosides, and phenicols, respectively.
Metabolic activity, urease production, antibiotic resistance and virulence in dual species biofilms of Staphylococcus epidermidis and Staphylococcus aureus.
The study identified the upregulation of antibiotic resistance genes in dual species biofilms of Staphylococcus epidermidis ET-024 and Staphylococcus aureus Mu50, including aacA, ermA-1, ermA-2, ermA-3, and mecA, which confer resistance to aminoglycosides, macrolides, and beta-lactams, respectively.
Comparative Genomics Study of Staphylococcus epidermidis Isolates from Orthopedic-Device-Related Infections Correlated with Patient Outcome.
The study identified biofilm formation and antibiotic resistance as associated with poor outcome in S. epidermidis ODRI, highlighting the roles of aacA, ccrA, ccrB, qacA, and bhp genes in resistance mechanisms.
Molecular cloning and analysis of Staphylococcus aureus chromosomal aminoglycoside resistance genes.
The study identified and characterized the chromosomal aminoglycoside resistance genes aphA and aacA in Staphylococcus aureus, which confer resistance to kanamycin, neomycin, and streptomycin. These genes were cloned and expressed in E. coli and B. subtilis, demonstrating their functionality.
Phenotypic and Genotypic Characterization of Acinetobacter spp. Panel Strains: A Cornerstone to Facilitate Antimicrobial Development.
The study characterized various AMR genes in Acinetobacter spp. including blaPER-1, blaTEM-1D, blaADC-31, blaOXA-82, aac(3')-Ia, aac(6')-Il, aph(3')-Ic, strAB, and others. Mutations in gyrA and parC were associated with fluoroquinolone resistance. Overexpression of efflux pumps like adeB and adeJ contributed to multidrug resistance.
Scarless Removal of Large Resistance Island AbaR Results in Antibiotic Susceptibility and Increased Natural Transformability in Acinetobacter baumannii.
The study shows that removing the AbaR resistance island from Acinetobacter baumannii restores antibiotic susceptibility and increases natural transformability. Several AMR genes within AbaR were identified, including aadB, aacC1, aphA1b, aacA, aadA1, strA, strB, blaVEB-1, blaOXA-10, sul1, dhfrI, dhfrX, tetA(A), tetA(G), cmlA1, cmlA5, cmlA9, catA1, arr-2, and sup.
Chicken Manure and Mushroom Residues Affect Soil Bacterial Community Structure but Not the Bacterial Resistome When Applied at the Same Rate of Nitrogen for 3 Years.
The study identified several antibiotic resistance genes (ARGs) in chicken manure, mushroom residues, and heat-treated chicken manure, highlighting the impact of different organic manures on the soil resistome. Key findings include the enrichment of specific ARGs such as aadE, aadD, qacE1, qacH, lnuA, vatE, and tetL in soils treated with various manures, indicating the potential for ARG transfer through manure application.
The association between the genetic structures of commonly incompatible plasmids in Gram-negative bacteria, their distribution and the resistance genes.
The study characterizes various resistance genes carried by incompatible plasmids in Gram-negative bacteria, highlighting their role in the spread of antibiotic resistance. Key genes include beta-lactamases like bla VIM-1, bla SHV-12, bla TEM-1B, and bla CTX-M-15, as well as sulfonamide resistance genes sul1 and sul2, tetracycline resistance gene tetA, and polymyxin resistance gene mcr-1.
Phenotypic and genotypic characterization of antimicrobial resistance and virulence profiles of Salmonella enterica serotypes isolated from necropsied horses in Kentucky.
The study identified several AMR genes in Salmonella enterica isolates from necropsied horses, including beta-lactamase genes (blaTEM, blaCTX-M, blaSHV2, blaOXA-9), aminoglycoside resistance gene (aacA[3]), sulfonamide resistance gene (sul2), amphenicol resistance gene (floR), tetracycline resistance gene (tetB), streptomycin resistance gene (strA), macrolide resistance gene (ermB2), and quinolone resistance gene (qnrB2). These genes were associated with resistance to multiple antibiotics, highlighting the presence of multidrug-resistant Salmonella strains.
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