Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA2
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| AadA2 | Reference Gene CatalogResFinder DatabaseReslit | 277 | STREPTOMYCIN, streptomycin +4 | Vibrio cholerae +111 | United States, Canada|France|Belgium|Scotland, Norway|Japan, Belgium, North Carolina|Virginia, Europe, Japan, Denmark, Bolivia, Singapore|Colombia|Guyana|Brazil|Manaos, Mexico, Tunisia, Hungary, India, US, Germany, Australia, Nepal, USA|Brazil|United States, South West London, UK, China, Okinawa Prefecture, Japan, Netherlands, Iran, Egypt, United States|New York|Florida|Illinois|Gaza|Colombia|South America|Mediterranean region, San Francisco|Seattle|Minnesota|Minneapolis|Sacramento|Dallas|Jackson, Delhi, India, North Carolina|China, Pakistan, United Kingdom, UK|Latin America, France, Thailand, Nigeria, Malawi, Cleveland, OH|Baltimore, MD, Brazil, Northern Thailand, South Africa, Vietnam, Italy, USA|Peru|Egypt|Cambodia|Kenya, Jakarta, Pacific region|Hawaii, Dominican Republic, Bangladesh, Finland|Malaysia|Poland|Lithuania|United States|Canada|China|Japan|Norway|Brazil|Netherlands|Hong Kong|Germany|Switzerland|Portugal|Australia|UK|Vietnam|Spain|Dominican Republic|India|Thailand, Guizhou, China, Alberta|Canada, Ghana, South Korea, Greece, Europe|Poland|USA|China|France, Ontario, Canada|North America, Spain, Europe|Denmark|France|Germany|United Kingdom, Romania|Spain, Brasília, Brazil, Europe|China|Egypt|Vietnam|Colombia, Canada, Cambodia, North Carolina|USA, India|United States, Caribbean, Europe|Greece, Finland|Eastern Finland, Taiwan, England, North-Western Mexico, southern Ontario, Canada, Georgia, USA|Georgia, North America|Asia|Europe|Middle East|Africa, Hong Kong, Southern Europe, Alberta, Canada, Italy|Taiwan|Spain|China|Australia|United States|Egypt|Bolivia, Al-Kharj, KSA, La Paz River basin, Bolivia|La Paz River basin, Portugal|Spain|Italy|Morocco, Portugal|Antarctic|South Shetland Islands|North Adriatic Sea|Bohai Sea|Adriatic Sea|Pacific Ocean|Baltic Sea, Ontario, Canada, Holtemme river, Saxony-Anhalt, Germany, Europe|Asia|North America|Western and South-Eastern Asia, Belgium|The Netherlands|Europe, United Kingdom|Thailand|UK, Comunitat Valenciana|Spain, Maryland|California|New York|Pennsylvania, Russia|Switzerland|Italy|USA|Norway|Spain|Ghana, Global|Guinea|Austria|Vietnam|China|Spain|Canada|Hong Kong|Malaysia|Germany|South Africa|Vancouver|Vienna, Europe|Portugal, Mexico|Japan|China|Israel|New Zealand|United States, Pakistan|Karachi, Pakistan, Spain|Asturias, Spain, Poland, Norway, New Hampshire, USA|global, Kuwait, Brazil|Belgium, Germany|Australia|Taiwan|USA|Canada|Denmark, Argentina, Beijing, Asia|North America|Europe|Australia, Bangkok, Thailand, Thailand|Pig|Pork, Accra, Ghana|Ghana, global, Ethiopia, Malaysia, Bulgaria|Europe, Portugal|various regions, Uruguay, Turkey, Europe|Midwestern United States, Alexandria, Egypt, Europe|Asia|South America|Africa|Germany|Vietnam|USA|Ecuador|China, Croatia, Shanghai|Minhang District, Western Balkans|Hungary, Inner Mongolia|Inner Mongolia, China, Europe|Italy, China|Lebanon|United States|Poland|France, Shenzhen, China, Asia|China, Africa, United Arab Emirates | 1999, 2000, 2001, 2003, 2004, 2005, 2006, 2007, 2008, 2009, 2010, 2011, 2012, 2013, 2014, 2015, 2016, 2017, 2018, 2019, 2020, 2021, 2022, 2023, 2024, 2025 | AF221903.1 | AAF97630.1 |
| ANT(3'') | Card Database | 1 | - | Klebsiella pneumoniae | - | - | AF156486.1 | AAF27727.1 |
| strA | Reslit | 291 | streptomycin, aminoglycosides +8 | Escherichia coli DH5alpha +152 | Germany, Asia, North Carolina|Virginia, Europe, France, Canada, Taiwan, Atlantic Canada, Spain, China, India|Sweden, Korea, India, Haiti, US, Berlin, Germany, China|Beijing, China, USA|Brazil|United States, Eastern China, Japan, Brazil|China|Hong Kong|Indonesia|Israel|Nigeria|Peru|Singapore|Thailand|Vietnam, Zambia, South West London, UK, Okinawa Prefecture, Japan, Los Angeles County, California, Japan|Thailand|Canada|France|Spain|South Korea|United Kingdom|Croatia|Vietnam|global, Eastern Cape, South Africa, Germany|Denmark|Sweden|France|Italy, poultry, Eastern Cape Province, South Africa, Israel, Malaysia, Texas|Nebraska|Alberta|France|Alberta, Canada|Nebraska, Texas, USA|Nantes, France, United States, Serbia, Greece, Europe|Portugal, Australia, Nepal|Japan, North America, United States|New York|Florida|Illinois|Gaza|Colombia|South America|Mediterranean region, South Korea, United Kingdom|Ireland, New York|Washington, San Francisco|Seattle|Minnesota|Minneapolis|Sacramento|Dallas|Jackson, Europe|Switzerland|Canada, North Carolina, California|Midwest|Germany|China, USA|Australia|Canada|Japan|France|Madagascar|China|Thailand|Germany, Global, Lake Michigan, Pakistan, West Africa|Conakry, Guinea, Cameroon, Nepal, UK|Latin America, Ghana, Europe|United States|China|Brazil|Australia|Spain|Germany|Iran|Switzerland|France|Portugal|Japan|Belgium|South Korea|Vietnam|Taiwan|India|Egypt|South Africa|Algeria, South Asia|sub-Saharan Africa|The Gambia|Mali|Kenya|Mozambique|Bangladesh|India|Pakistan, Global|global, Bangladesh|Sweden, Thailand|Japan, United Kingdom|Brazil, Bangladesh|Pakistan|Nepal, Argentina, Montreal, Canada, Australia|Denmark, Malawi, Mexico, Denmark|France|Poland|Italy|Hungary|Germany|Estonia|United States, Europe|Switzerland, developing countries, Ecuador, Vietnam, North America|Washington, Brazil, Utah, Northern Thailand, South Africa, Lebanon, Lake Victoria, Tanzania, Belgium, Southern China, northern Xinjiang, China|China, Bolivia, mid-Adriatic coast, China|USA|Italy|Israel, Europe|Italy, Italy|Colombia|United States|South Africa|India|Greece|North Africa, South Africa|various water sources, USA|Peru|Egypt|Cambodia|Kenya, Vietnam|China, Karnataka, Southern India, Italy, Russia, Egypt, Kenya, England, Tokyo, Japan|Japan, California|Europe|North America|Republic of Congo, India|Malaysia|South China, Europe|broiler production pyramid, Thailand, Norway, Northeastern Ohio, the United States|Northeastern Ohio, Europe|Greece, Europe|Asia, Central China|China, Mecklenburg-Western Pomerania, Europe|North America|Netherlands|Denmark|Pennsylvania|United States|France, United Kingdom, North America|Europe|Asia|Oceania|South America, Madagascar, Georgia, USA|Georgia, Hubei, China|China, Germany|Colombia|Vietnam|Japan|Nicaragua|United States|Canada|Brazil|Thailand|Lebanon|Poland|France|Italy|Spain|Portugal|Mexico|China|South Korea|India, Europe|USA|Portugal|Germany|Australia|China|India|Pakistan|Sweden|Colorado, Ethiopia|Kenya, poultry farms in China, Henan|Hubei|Hunan|Anhui|Jiangxi|Shaanxi|Shanxi, Democratic Republic of Congo|Democratic Republic of the Congo, North Sea|Baltic Sea, Southwest Nigeria, Anhui, China, Atlantic salmon, Mexico|Japan|China|Israel|New Zealand|United States, Khartoum State, Sudan, Kuwait, Alexandria, Egypt, Iran, Wales|Nigeria, Permafrost sample from Laptev Sea Coast|China|clinical settings, South-Western districts of Uganda, Oman, France|South America|Europe|Asia|North Africa, Europe|United States|Asia|Africa|Australia|Bangladesh, Bangkok, Thailand, Shanghai, China, Baton Rouge, LA, United States|Pakistan|Bangladesh|Nigeria|Iraq|India, Pakistan|China|United States|United Kingdom|Canada|Australia|Spain|Denmark|UAE|Ethiopia|India|South Asia, Armenia, Europe|Africa|North America|South America|Asia|Oceania, Kentucky|USA, Poland, Central Zone of Mexico|Mexico, Nigeria, Guangzhou, China, Bangladesh, Western Balkans|Hungary, Norway|Sweden, Northern Nigeria|Nigeria, Shenzhen, China, East Africa|Tanzania|Uganda, Middle East|Europe|Asia|South America|Peru|Egypt|Saudi Arabia|Denmark|Pakistan|Jordan|Iraq|Lebanon|China|Ghana, Africa | 2000, 2001, 2003, 2005, 2006, 2008, 2009, 2011, 2012, 2013, 2014, 2015, 2016, 2017, 2018, 2019, 2020, 2021, 2022, 2023, 2024, 2025, 2026 | AJ271879|AF070999 | - |
| strA/B | Reslit | 8 | streptomycin, gentamicin +1 | Escherichia coli +5 | Brazil, Iraq, Denmark, Germany|France|Netherlands|Belgium, United States|coastal wetlands, Italy|Europe, India | 2003, 2012, 2016, 2017, 2020, 2021, 2023 | JWJM00000000 | - |
| aadA2 | ResFinder Database | 1 | STREPTOMYCIN, SPECTINOMYCIN | Escherichia coli | - | 2007 | 10870, JQ364967 | - |
| strA/strB | Reslit | 8 | streptomycin, aminoglycosides | Escherichia coli +3 | Germany, Europe|Spain|Hungary|Germany|France|Belgium|Poland|United Kingdom|Denmark, Poland, Japan, Turkey, France | 2009, 2021, 2022, 2023, 2024, 2025 | LT669764.1|CP008734.1|KX618704|CP018772|CP017980.1|NZ_CP009072.1|CP009072.1|CP018773.2 | - |
| strA/aph(3'')-Ib | Reslit | 1 | streptomycin | Erwinia amylovora +1 | Denmark | 2013 | ALPW00000000|AOSP00000000 | - |
| Aad(A2) | Reslit | 1 | streptomycin | Aeromonas salmonicida | Europe | 2018 | PRJNA377399 | - |
| aadA2-03 | Reslit | 1 | aminoglycosides | - | Australia | 2020 | SRP201741 | - |
| aadA2-02 | Reslit | 2 | aminoglycosides | Aeromonas veronii | Australia, China | 2020, 2023 | SRP201741 | - |
| aadA-02 | Reslit | 2 | aminoglycosides | Escherichia +2 | Australia, Europe | 2020, 2022 | SRP201741 | - |
| aadA-03 | Reslit | 1 | aminoglycosides | - | Australia | 2020 | SRP201741 | - |
| str A | Reslit | 6 | streptomycin | Escherichia coli +4 | northern Xinjiang, China|China, Edo state, Nigeria, Southeast Nigeria, South Africa, Northern Spain, France|Hungary | 2020, 2022, 2024, 2025 | JAIKTX000000000|JAIKUW000000000|JAIKTX010000000|JAIKUW010000000 | - |
| aad A2 | Reslit | 4 | streptomycin, aminoglycosides | Klebsiella pneumoniae +3 | Italy, Ontario, Canada, Guangdong, China | 2020, 2022, 2025 | ERS12773674|ERS12773675|ERS12773676|ERS12773677|ERS12773678|ERS12773679|ERS12773680|ERS12773681|ERS12773682|ERS12773683|ERS12773684|ERS12773685|ERS12773686|ERS12773687|ERS12773688|ERS12773689|ERS12773690|ERS12773691|ERS12773692|ERS12773693|ERS12773694|ERS12773695|ERS12773696|ERS12773697|ERS12773698|ERS12841964|ERS12841965|ERS12841966|ERS12841967|ERS12841968|ERS12841969|ERS12841970|ERS12841971|ERS12841972|ERS12841973|ERS12841974|ERS12413439|Ers12413440|CP023897|CP024806|KX523903|MG570092|KX894452|CP026476|MG228426|NZ_CP040399.1 | - |
| str A/B | Reslit | 3 | streptomycin | Salmonella enterica serovar Typhimurium +3 | Bangladesh, Iran | 2021, 2022, 2025 | - | - |
| aadA 2 | Reslit | 2 | streptomycin, aminoglycosides | Escherichia coli +1 | Southeast Nigeria, Iran | 2022, 2025 | PRJEB43719 | - |
| aadA2/qacEdelta | Reslit | 1 | aminoglycosides | - | South Australia|New South Wales | 2024 | OR095837|OR095838|OR095839|OR095840|OR095841|OR095842|OR095843|OR095845|OR095846|OR095847|OR095848|OR095849|OR095850|OR095851|OR095852|OR095853|OR095854|OR095855|OR095856 | - |
Molecular characterization of an antibiotic resistance gene cluster of Salmonella typhimurium DT104.
Characterization and chromosomal mapping of antimicrobial resistance genes in Salmonella enterica serotype typhimurium.
Exogenous Isolation of Antibiotic Resistance Plasmids from Piggery Manure Slurries Reveals a High Prevalence and Diversity of IncQ-Like Plasmids.
The study identifies multiple IncQ-like plasmids from piggery manure that confer resistance to various antibiotics, including streptomycin, sulfonamide, chloramphenicol, kanamycin, tetracycline, and streptothricin.
Transposons Tn1696 and Tn21 and Their Integrons In4 and In2 Have Independent Origins
The study characterizes the integrons In4 and In2 found in transposons Tn1696 and Tn21, identifying specific genes such as aadA2, aacC1, and cmlA1 that confer resistance to streptomycin, spectinomycin, gentamicin, and chloramphenicol.
Identification and characterization of integron-mediated antibiotic resistance among Shiga toxin-producing Escherichia coli isolates.
The study identifies class 1 integrons in Shiga toxin-producing Escherichia coli (STEC) isolates, including the aadA, aadA1, aadA2, and dfrXII genes, which confer resistance to streptomycin, spectinomycin, and trimethoprim.
Complete nucleotide sequence of a 43-kilobase genomic island associated with the multidrug resistance region of Salmonella enterica serovar Typhimurium DT104 and its identification in phage type DT120 and serovar Agona.
The study characterizes the multidrug resistance region of Salmonella enterica serovar Typhimurium DT104, identifying genes such as aadA2, floR, qacE delta1, sulI delta1, and tet(G) that confer resistance to various antibiotics.
Molecular analysis of antibiotic resistance gene clusters in vibrio cholerae O139 and O1 SXT constins.
The study identifies the antibiotic resistance genes in Vibrio cholerae O139 and O1 SXT constins, including floR, strA, strB, sulII, and dfr18, which confer resistance to chloramphenicol, streptomycin, sulfamethoxazole, and trimethoprim, respectively.
Characterization of integron mediated antimicrobial resistance in Salmonella isolated from diseased swine.
The study identified two integrons in Salmonella Typhimurium DT104 strains, one containing aadA2 which confers resistance to streptomycin and another containing blaPSE-1 which confers resistance to ampicillin. Non-DT104 strains showed varying levels of resistance but lacked the specific integron patterns seen in DT104.
Integron-containing IncU R plasmids pRAS1 and pAr-32 from the fish pathogen Aeromonas salmonicida.
The study identified the dfrA16 gene in the integron of plasmid pRAS1, which confers resistance to trimethoprim, and the aadA2 gene in the integron of plasmid pAr-32, which confers resistance to streptomycin and kanamycin.
New plasmid-borne antibiotic resistance gene cluster in Pasteurella multocida.
The study identifies a novel plasmid-borne antibiotic resistance gene cluster in Pasteurella multocida, including sul2 for sulfonamide resistance, strA and strB for streptomycin resistance, and tet(H) for tetracycline resistance.
Multidrug-resistant Shiga toxin-producing Escherichia coli 0118:H16 Latin America.
The study reports the first isolation of a multidrug-resistant STEC O118:H16 strain from cattle in Latin America, highlighting the presence of various AMR genes such as blaTEM1-like, aphA1, strA/B, sul2, and tet[A].
Salmonella genomic island 1 multidrug resistance gene clusters in Salmonella enterica serovar Agona isolated in Belgium in 1992 to 2002.
The study identifies various multidrug resistance gene clusters in Salmonella enterica serovar Agona, including SGI1-A, SGI1-G, and several deletion variants. Key genes include floR, aadA2, pse-1, dfrA10, and orf513, which confer resistance to multiple antibiotics.
Mechanisms of resistance in multiple-antibiotic-resistant Escherichia coli strains of human, animal, and food origins.
The complete sequences of plasmids pB2 and pB3 provide evidence for a recent ancestor of the IncP-1beta group without any accessory genes.
Complete nucleotide sequence of the conjugative tetracycline resistance plasmid pFBAOT6, a member of a group of IncU plasmids with global ubiquity.
The study describes the complete sequence of the IncU plasmid pFBAOT6, identifying the tetracycline resistance gene tetA(A) and the streptomycin resistance gene aadA2.
Multidrug-resistant Salmonella enterica serovar Muenchen from pigs and humans and potential interserovar transfer of antimicrobial resistance.
The study identifies several AMR genes in multidrug-resistant Salmonella enterica serovar Muenchen isolates from pigs and humans, including blaOXA-30, aadA2, aphA1-Iab, tetA(B), blaTEM, strA, cmlA, and tetA(A). These genes confer resistance to various antibiotics such as ampicillin, amoxicillin-clavulanic acid, streptomycin, kanamycin, tetracycline, chloramphenicol, and gentamicin.
Multidrug-resistant Salmonella enterica serovar Muenchen from pigs and humans and potential interserovar transfer of antimicrobial resistance.
The study identifies several AMR genes in multidrug-resistant Salmonella enterica serovar Muenchen isolates from pigs and humans, including blaOXA-30, aadA2, aphA1-Iab, tetA(B), blaTEM, strA, cmlA, and tetA(A). These genes confer resistance to various antibiotics such as ampicillin, amoxicillin-clavulanic acid, streptomycin, kanamycin, tetracycline, chloramphenicol, and gentamicin.
The genome sequence of Salmonella enterica serovar Choleraesuis, a highly invasive and resistant zoonotic pathogen.
The study identifies multiple antimicrobial resistance genes on plasmids pSC138 and pSCV50 in Salmonella enterica serovar Choleraesuis SC-B67, including blaTEM-1, blaCMY-2, tetRA, strA, aadA2, sulI, sulII, catI, cmlA, aph, sat, mef, mer, ebr, qac, and blaTEM-67. Additionally, mutations in the chromosomal genes gyrA and parC, along with the inactivation of acrR, contribute to ciprofloxacin resistance.
The genome sequence of Salmonella enterica serovar Choleraesuis, a highly invasive and resistant zoonotic pathogen.
The study identifies multiple antimicrobial resistance genes on plasmids pSC138 and pSCV50 in Salmonella enterica serovar Choleraesuis SC-B67, including blaTEM-1, blaCMY-2, tetRA, strA, aadA2, sulI, sulII, catI, cmlA, aph, sat, mef, mer, ebr, qac, and blaTEM-67. Additionally, mutations in the chromosomal genes gyrA and parC, along with the inactivation of acrR, contribute to ciprofloxacin resistance.
Characterization of isolates of Salmonella enterica serovar typhimurium displaying high-level fluoroquinolone resistance in Japan.
The study identifies high-level fluoroquinolone-resistant Salmonella enterica serovar Typhimurium isolates with mutations in gyrA (S83F, D87N/G) and parC (S80R), along with resistance genes blaOXA-30, aadA1, dhfr12, aadA2, aac3, catA, and tetRA.
Class 1 integrons and tetracycline resistance genes in alcaligenes, arthrobacter, and Pseudomonas spp. isolated from pigsties and manured soil.
The study identifies several tetracycline resistance genes (tet(A), tet(C), tet(33)) and gene cassettes (aadA1, aadA2, aadA9, aadA11, dfrA1, dfrB2a) associated with class 1 integrons in various bacterial species isolated from pigsties and manured soil.
Macrolide inactivation gene cluster mphA-mrx-mphR adjacent to a class 1 integron in Aeromonas hydrophila isolated from a diarrhoeic pig in Oklahoma.
Comparative genomics of multidrug resistance in Acinetobacter baumannii.
The study identifies numerous resistance genes in the multidrug-resistant Acinetobacter baumannii strain AYE, including beta-lactamases, aminoglycoside-modifying enzymes, tetracycline resistance genes, and others, highlighting the complexity of its resistance mechanisms.
Analysis of integrons in clinical isolates of Escherichia coli in China during the last six years.
Organization of tn2610 containing two transposition modules.
The study characterizes the multidrug resistance transposon Tn2610, identifying several resistance genes including ereB, pse-1, aadA2, and sul1, which confer resistance to erythromycin, ampicillin, streptomycin, and sulfonamide, respectively.
Characterization of antimicrobial resistance of Salmonella Newport isolated from animals, the environment, and animal food products in Canada.
The study identified several AMR genes in Salmonella Newport isolates, including bla CMY-2, flo st, strA, strB, sulII, tetA, and aphA-1, which confer resistance to various antibiotics such as extended-spectrum cephalosporins, chloramphenicol, streptomycin, sulfonamides, tetracycline, kanamycin, and neomycin.
Complete nucleotide sequence of pK245, a 98-kilobase plasmid conferring quinolone resistance and extended-spectrum-beta-lactamase activity in a clinical Klebsiella pneumoniae isolate.
The study identifies the plasmid pK245 carrying the qnrS quinolone resistance gene and the blaSHV-2 extended-spectrum beta-lactamase gene, along with other resistance genes such as aacC2, strA, strB, catA2, sul2, tetD, and dfrA14, which confer resistance to multiple antimicrobial classes in Klebsiella pneumoniae.
Molecular differentiation of common promoters in Salmonella class 1 integrons.
Population structure and resistance genes in antibiotic-resistant bacteria from a remote community with minimal antibiotic exposure.
The study identified various acquired antibiotic resistance genes in commensal E. coli isolates from a remote community with minimal antibiotic exposure, including blaTEM, catI, cmlA6, tet(A), tet(B), dfrA1, dfrA7, dfrA8, dfrA17, sul1, sul2, aphA1, aadA1, aadA2, aadA5, aadB, and sat-1. These genes were found to be similar to those seen in antibiotic-exposed settings, indicating the dissemination of resistant bacteria and resistance genes from such environments.
Manure and sulfadiazine synergistically increased bacterial antibiotic resistance in soil over at least two months.
Sequencing and comparative genomic analysis of pK29, a 269-kilobase conjugative plasmid encoding CMY-8 and CTX-M-3 beta-lactamases in Klebsiella pneumoniae., Characterization of an IncFII plasmid encoding NDM-1 from Escherichia coli ST131.
Comparative analysis of IncHI2 plasmids carrying blaCTX-M-2 or blaCTX-M-9 from Escherichia coli and Salmonella enterica strains isolated from poultry and humans.
Different pathways to acquiring resistance genes illustrated by the recent evolution of IncW plasmids.
The study characterizes the acquisition of resistance genes via different pathways in IncW plasmids, highlighting the role of integrons and transposons in the spread of antibiotic resistance.
Different pathways to acquiring resistance genes illustrated by the recent evolution of IncW plasmids.
The study characterizes the acquisition of resistance genes via different pathways in IncW plasmids, highlighting the role of integrons and transposons in the spread of antibiotic resistance.
Transferable, multiple antibiotic and mercury resistance in Atlantic Canadian isolates of Aeromonas salmonicida subsp. salmonicida is associated with carriage of an IncA/C plasmid similar to the Salmonella enterica plasmid pSN254.
The study identifies multiple antibiotic and mercury resistance genes carried by an IncA/C plasmid in Atlantic Canadian isolates of Aeromonas salmonicida subsp. salmonicida, including aadA7, floR, tetA, sulII, strA, strB, blaCMY-2, and a mercury resistance operon.
Antimicrobial resistance genes in Escherichia coli isolates recovered from a commercial beef processing plant
The study identified various antimicrobial resistance genes in E. coli isolates from a commercial beef processing plant, including beta-lactamase genes (blaCMY, blaSHV, blaTEM), tetracycline resistance genes (tetA, tetB, tetC), sulfonamide resistance genes (sul1, sul2), and aminoglycoside resistance genes (strA, strB).
Multiresistance in Pasteurella multocida is mediated by coexistence of small plasmids.
The study identifies several AMR genes, including bla ROB-1, tet(B), tet(H), tet(O), strA, and sul2, which are responsible for multidrug resistance in Pasteurella multocida. These genes are located on small plasmids and contribute to resistance against beta-lactams, tetracyclines, streptomycin, and sulfamethoxazole.
Genetic relatedness and molecular characterization of multidrug resistant Acinetobacter baumannii isolated in central Ohio, USA.
Antimicrobial resistances do not affect colonization parameters of intestinal E. coli in a small piglet group.
The study identified various AMR genes in commensal E. coli from pigs, including blaTEM, catA1, aph(3')-Ia, aadA, strA/strB, tet(A), tet(B), sul1, sul2, and sul3. These genes conferred resistance to antibiotics such as ampicillin, chloramphenicol, kanamycin, neomycin, streptomycin, spectinomycin, tetracycline, and sulfamethoxazole. However, the presence of these resistance genes did not provide a significant colonization advantage or disadvantage in the pig intestine.
Genome sequence of the versatile fish pathogen Edwardsiella tarda provides insights into its adaptation to broad host ranges and intracellular niches.
The study identifies multiple AMR genes in Edwardsiella tarda EIB202, including tetA, tetR, strA, strB, sulII, and catA3, which confer resistance to tetracycline, streptomycin, sulfonamide, and chloramphenicol.
High prevalence of multidrug-tolerant bacteria and associated antimicrobial resistance genes isolated from ornamental fish and their carriage water.
The study identified a high prevalence of multidrug-tolerant bacteria and various antimicrobial resistance genes in ornamental fish and their carriage water, highlighting the potential risk of resistance gene spread through the aquatic environment.
A predominant multidrug-resistant Salmonella enterica serovar Saintpaul clonal line in German turkey and related food products.
Activity of a novel aminoglycoside, ACHN-490, against clinical isolates of Escherichia coli and Klebsiella pneumoniae from New York City.
Carbapenem-hydrolyzing GES-type extended-spectrum beta-lactamase in Acinetobacter baumannii.
Salmonella Typhimurium ST213 is associated with two types of IncA/C plasmids carrying multiple resistance determinants.
The study identifies bla CMY-2, dfrA12, orfF, aadA2, floR, and mer as resistance genes carried by IncA/C plasmids in Salmonella Typhimurium ST213, contributing to multidrug resistance.
Pyrosequencing of antibiotic-contaminated river sediments reveals high levels of resistance and gene transfer elements.
The study identifies high levels of resistance genes, including sul2, strA, strB, and qnrD, in river sediments contaminated with antibiotics, highlighting the role of environmental microbial communities in the dissemination of antibiotic resistance.
Antimicrobial resistance, virulence-associated genes, and pulsed-field gel electrophoresis profiles of Salmonella enterica subsp. enterica serovar Typhimurium isolated from piglets with diarrhea in Korea.
The study identified multiple antimicrobial resistance genes in Salmonella enterica subsp. enterica serovar Typhimurium isolates from piglets with diarrhea in Korea, including bla PSE, bla TEM, cat1, cat2, floR, strA, strB, aadA, sulI, sulII, tetA, tetC, and tetG.
QRDR mutations, efflux system & antimicrobial resistance genes in enterotoxigenic Escherichia coli isolated from an outbreak of diarrhoea in Ahmedabad, India.
The study identified QRDR mutations in gyrA and parC, as well as the aac(6')-Ib-cr gene, class 1 and class 2 integrons, and various resistance genes including blaTEM-1, catA1, dfrA1, dfrA17, aadA1, aadA5, strA, tet, and aphA1-Ia in ETEC strains, contributing to multidrug resistance.
Phenotypic and genotypic characterization of Salmonella enterica recovered from poultry meat in Tunisia and identification of new genetic traits.
The study identified various AMR genes in Salmonella enterica isolates from poultry meat in Tunisia, including blaTEM, aadA1, aadA2, dfrA1, sul1, sul2, sul3, strA-strB, cmlA, and tet(A). These genes contribute to resistance against multiple antibiotics such as ampicillin, sulfonamides, streptomycin, trimethoprim, chloramphenicol, and tetracycline.
Drug-resistance mechanisms in Vibrio cholerae O1 outbreak strain, Haiti, 2010.
The study identified resistance genes strA, strB, sul2, dfrA1, and floR in the Haiti V. cholerae O1 outbreak strain, along with mutations in gyrA (Ser83Ile) and parC (Ser85Leu) contributing to quinolone resistance.
Stability, entrapment and variant formation of Salmonella genomic island 1.
The study identifies and characterizes several AMR genes within the Salmonella genomic island 1 (SGI1), including aadA2, blaPSE-1, floR, qacEΔ1sulΔ1, qacEΔ1sul1, and tet(G). These genes confer resistance to various antibiotics such as streptomycin, spectinomycin, ampicillin, chloramphenicol, florfenicol, sulfonamides, and tetracycline.
Characterization of an IncFII plasmid encoding NDM-1 from Escherichia coli ST131.
The study characterizes an IncFII plasmid carrying the blaNDM-1 gene, along with other resistance genes such as aacA4, aadA2, aacC2, and blaOXA-1, which contribute to multidrug resistance in E. coli ST131.
Characterization of an IncFII plasmid encoding NDM-1 from Escherichia coli ST131.
Characterization of an IncFII plasmid encoding NDM-1 from Escherichia coli ST131.
Identification of acquired antimicrobial resistance genes.
The study presents ResFinder, a web-based tool for identifying acquired antimicrobial resistance genes in whole-genome data. It successfully identifies resistance genes with high accuracy and agrees with phenotypic testing. The tool detects various resistance genes across different bacterial species, including beta-lactamases, aminoglycoside modifying enzymes, tetracycline resistance genes, and others.
Characteristics of plasmids in multi-drug-resistant Enterobacteriaceae isolated during prospective surveillance of a newly opened hospital in Iraq.
The study identified various plasmid-borne antimicrobial resistance genes in multi-drug-resistant Enterobacteriaceae isolates from a newly opened hospital in Iraq, including aminoglycoside, beta-lactam, sulfamethoxazole/trime-thoprim, tetracycline, and chloramphenicol resistance genes.
Natural transformation facilitates transfer of transposons, integrons and gene cassettes between bacterial species.
The study demonstrates that natural transformation facilitates the transfer of transposons, integrons, and gene cassettes between bacterial species, leading to the acquisition of antibiotic resistance traits. Specific resistance genes such as aadB, blaIMP-5, blaOXA-30, dfrA12, aadA2, and aacA4 were identified and characterized.
Identification of novel genomic islands and transposons encoding genes that may contribute to host specificity and Salmonella transmission
The study identified various antibiotic resistance genes in Salmonella plasmids, including beta-lactamases (bla CTX, bla CMY, bla TEM), aminoglycoside resistance genes (aadA1, aadA2, strA, strB), tetracycline resistance gene (tetA), chloramphenicol resistance gene (cmlA), sulfonamide resistance gene (sul2), and genes conferring resistance to heavy metals and disinfectants (sugE, arsR, cusR, silE, qacH).
Identification of novel genomic islands and transposons encoding genes that may contribute to host specificity and Salmonella transmission
The study identified various antibiotic resistance genes in Salmonella plasmids, including beta-lactamases (bla CTX, bla CMY, bla TEM), aminoglycoside resistance genes (aadA1, aadA2, strA, strB), tetracycline resistance gene (tetA), chloramphenicol resistance gene (cmlA), sulfonamide resistance gene (sul2), and genes conferring resistance to heavy metals and disinfectants (sugE, arsR, cusR, silE, qacH).
Development and Evaluation of a Microarray-Based Serogenotyping Assay for Salmonella
The study presents a microarray-based serogenotyping assay for Salmonella, demonstrating high correlation between genotypic and phenotypic characteristics. Several AMR genes were identified and validated, showing strong association with AMR phenotypes.
Development and Evaluation of a Microarray-Based Serogenotyping Assay for Salmonella
The study presents a microarray-based serogenotyping assay for Salmonella, demonstrating high correlation between genotypic and phenotypic characteristics. Several AMR genes were identified and validated, showing strong association with AMR phenotypes.
Enhanced antibiotic multi-resistance in nasal and faecal bacteria after agricultural use of streptomycin.
The study found that agricultural use of streptomycin leads to increased multidrug resistance in nasal and faecal bacteria, including streptomycin resistance genes strA, strB, aadA, and class 1 integron intI1.
New integron gene arrays from multiresistant clinical isolates of members of the Enterobacteriaceae and Pseudomonas aeruginosa from hospitals in Malaysia.
Frequent combination of antimicrobial multiresistance and extraintestinal pathogenicity in Escherichia coli isolates from urban rats (Rattus norvegicus) in Berlin, Germany.
The study identified multidrug-resistant Escherichia coli strains in urban rats, including an ESBL-producing strain (IMT20717) carrying bla CTX-M-9, bla TEM-1-like, sul2, strA, strB, aac(6′)-Ib-cr, and aadA. These strains exhibited resistance to multiple antimicrobial classes, including beta-lactams, aminoglycosides, and fluoroquinolones.
DNA sequence analysis of plasmids from multidrug resistant Salmonella enterica serotype Heidelberg isolates.
The study identified multiple antimicrobial resistance genes in plasmids from multidrug-resistant Salmonella enterica serotype Heidelberg isolates, including bla CMY, aadA, aadB, aphA, strA, strB, sul1, sul2, tetA, floR, cmlA, dfrA1, dfrA12, and aacC.
Comparative genomic analysis of rapid evolution of an extreme-drug-resistant Acinetobacter baumannii clone.
The study identifies multiple AMR genes and mutations in the EDR A. baumannii 53264 strain, including aac(6')-Iaf, aac(3)-Ia, aph(3')-Ia, aph(3')-Ic, strA/aph(3'')-Ib, blaOXA-23, blaTEM-1, sul1, sul3, and tet(B). Additionally, mutations in ampC, gyrB, parC, and qseC contribute to resistance against various antibiotics.
Into the wild: dissemination of antibiotic resistance determinants via a species recovery program.
Class 1 integrons containing gene cassettes encoding resistance to streptomycin, spectinomycin, and trimethoprim were detected in captive brush-tailed rock wallabies, suggesting acquisition from human or domestic animal sources.
Into the wild: dissemination of antibiotic resistance determinants via a species recovery program.
Into the wild: dissemination of antibiotic resistance determinants via a species recovery program.
Complete genome analysis of three Acinetobacter baumannii clinical isolates in China for insight into the diversification of drug resistance elements.
The study identifies multiple AMR genes and resistance islands in three multidrug-resistant Acinetobacter baumannii isolates, highlighting the role of genomic plasticity in the dissemination of resistance mechanisms.
DNA microarray for genotyping antibiotic resistance determinants in Acinetobacter baumannii clinical isolates.
The study developed a DNA microarray for genotyping antibiotic resistance determinants in Acinetobacter baumannii clinical isolates, identifying numerous resistance genes and mutations associated with carbapenem, aminoglycoside, fluoroquinolone, and other antibiotic resistances.
Antibiotic resistance determinants in a Pseudomonas putida strain isolated from a hospital.
The study identifies multiple antibiotic resistance genes in Pseudomonas putida HB3267, including aminoglycoside modifying enzymes, beta-lactamases, and sulfonamide resistance genes, contributing to its multidrug resistance profile.
NDM-1 Metallo-β-Lactamase and ArmA 16S rRNA methylase producing Providencia rettgeri clinical isolates in Nepal.
The study identifies multidrug-resistant Providencia rettgeri clinical isolates in Nepal carrying bla NDM-1, bla OXA-72, and armA genes, which confer resistance to carbapenems and aminoglycosides.
Diversity of plasmids encoding resistance and virulence functions in Salmonella enterica subsp. enterica serovar Typhimurium monophasic variant 4,[5],12:i:- strains circulating in Europe.
The study identifies various AMR genes in Salmonella enterica subsp. enterica serovar Typhimurium monophasic variant 4,[5],12:i:- strains, including aac(3)-IV, bla TEM-1, cmlA1, aadA1, aadA2, strA, sul1, sul2, sul3, tet(A), tet(B), and dfrA12, which confer resistance to multiple antibiotics.
Diversity of plasmids encoding resistance and virulence functions in Salmonella enterica subsp. enterica serovar Typhimurium monophasic variant 4,[5],12:i:- strains circulating in Europe.
The study identifies various AMR genes in Salmonella enterica subsp. enterica serovar Typhimurium monophasic variant 4,[5],12:i:- strains, including aac(3)-IV, bla TEM-1, cmlA1, aadA1, aadA2, strA, sul1, sul2, sul3, tet(A), tet(B), and dfrA12, which confer resistance to multiple antibiotics.
Comparative genomic analysis and virulence differences in closely related salmonella enterica serotype heidelberg isolates from humans, retail meats, and animals.
The study identified several AMR genes and mutations in Salmonella enterica serotype Heidelberg isolates, including bla, aac(6')-Ib, tet(M), qnrS1, and erm(B). Mutations in genes such as SEEHRA37_03221, SEEHRA37_24108, and others were associated with resistance traits.
Comparative genomic analysis and virulence differences in closely related salmonella enterica serotype heidelberg isolates from humans, retail meats, and animals.
The study identified several AMR genes and mutations in Salmonella enterica serotype Heidelberg isolates, including bla, aac(6')-Ib, tet(M), qnrS1, and erm(B). Mutations in genes such as SEEHRA37_03221, SEEHRA37_24108, and others were associated with resistance traits.
Characterization of multidrug-resistant Salmonella enterica serovars Indiana and Enteritidis from chickens in Eastern China.
The study identified multiple AMR genes including blaTEM, floR, tetA, strA, and aac(6')-Ib-cr in multidrug-resistant Salmonella enterica serovars Indiana and Enteritidis from chickens in Eastern China.
Characterization of multi-antibiotic-resistant Escherichia coli Isolated from beef cattle in Japan.
The study identified multiple AMR genes in E. coli isolates from beef cattle in Japan, highlighting the diversity of resistance mechanisms and the potential for horizontal gene transfer.
Resistance determinants and mobile genetic elements of an NDM-1-encoding Klebsiella pneumoniae strain.
The study identifies multiple antibiotic resistance genes in the NDM-1-encoding Klebsiella pneumoniae strain, including eight beta-lactamase genes and various other resistance determinants, highlighting the complexity of its resistance profile.
Characterization of microbiota composition and presence of selected antibiotic resistance genes in carriage water of ornamental fish.
The study identified several antibiotic resistance genes including sul1, tet(A), strA, aadA, cat, tet(G), and sul2 in the microbiota of ornamental fish carriage water. These genes were found to be prevalent and associated with various bacterial families.
Complete proteome of a quinolone-resistant Salmonella Typhimurium phage type DT104B clinical strain.
The study identifies the aac(6')-Ib-cr4, strA, and sul2 genes as responsible for aminoglycoside, fluoroquinolone, and sulfonamide resistance in the quinolone-resistant Salmonella Typhimurium DT104B clinical strain Se20.
Genomic signature of multidrug-resistant Salmonella enterica serovar typhi isolates related to a massive outbreak in Zambia between 2010 and 2012.
The study identifies multiple antimicrobial resistance genes in multidrug-resistant Salmonella enterica serovar Typhi isolates from Zambia, including strA, strB, blaTEM-1, sul1, sul2, dfrA7, and catA1. Mutations in the gyrA gene were also associated with fluoroquinolone resistance.
Phylogenetic distribution and prevalence of genes encoding class I Integrons and CTX-M-15 extended-spectrum β-lactamases in Escherichia coli isolates from healthy humans in Chandigarh, India.
The study identifies the presence of class 1 integrons and bla CTX-M-15 genes in commensal E. coli isolates from healthy individuals in Chandigarh, India. It also detects several gene cassettes conferring resistance to trimethoprim, streptomycin, spectinomycin, streptothricin, chloramphenicol, tetracycline, and sulfonamides.
Antimicrobial resistance characteristics and fitness of Gram-negative fecal bacteria from volunteers treated with minocycline or amoxicillin.
The study identified various AMR genes, including bla TEM, dfr, strB, tet(A), and tet(B), in Gram-negative fecal bacteria from volunteers treated with amoxicillin, minocycline, or placebo. The prevalence of these genes increased significantly in the amoxicillin-treated group.
Antimicrobial resistance characteristics and fitness of Gram-negative fecal bacteria from volunteers treated with minocycline or amoxicillin.
The study identified various AMR genes, including bla TEM, dfr, strB, tet(A), and tet(B), in Gram-negative fecal bacteria from volunteers treated with amoxicillin, minocycline, or placebo. The prevalence of these genes increased significantly in the amoxicillin-treated group.
Identification and characterization of a serious multidrug resistant Stenotrophomonas maltophilia strain in China.
The study identifies a multidrug-resistant Stenotrophomonas maltophilia strain WJ66 with resistance genes aadA2, qepA, and QnrB, along with mutations in gyrA, parC, and parE contributing to fluoroquinolone resistance.
Resistance phenotypes and genotypes among multiple-antimicrobial-resistant Salmonella enterica subspecies enterica serovar Choleraesuis strains isolated between 2008 and 2012 from slaughter pigs in Okinawa Prefecture, Japan.
The study identified multiple antimicrobial resistance genes in Salmonella enterica subspecies enterica serovar Choleraesuis strains, including blaTEM, strA, strB, aadA1, aadA2, aphA1, aacC2, tetB, sul1, sul2, dhfrXII, and dhfrXIII. Additionally, mutations in the QRDRs of gyrA and parC were associated with quinolone resistance.
Resistance phenotypes and genotypes among multiple-antimicrobial-resistant Salmonella enterica subspecies enterica serovar Choleraesuis strains isolated between 2008 and 2012 from slaughter pigs in Okinawa Prefecture, Japan.
The study identified multiple antimicrobial resistance genes in Salmonella enterica subspecies enterica serovar Choleraesuis strains, including blaTEM, strA, strB, aadA1, aadA2, aphA1, aacC2, tetB, sul1, sul2, dhfrXII, and dhfrXIII. Additionally, mutations in the QRDRs of gyrA and parC were associated with quinolone resistance.
Complete genome sequence of hypervirulent and outbreak-associated Acinetobacter baumannii strain LAC-4: epidemiology, resistance genetic determinants and potential virulence factors.
The study characterizes the resistance genetic determinants of the hypervirulent Acinetobacter baumannii strain LAC-4, identifying multiple beta-lactamases, aminoglycoside modifying enzymes, and RND-type efflux pumps contributing to its multidrug resistance.
Clinical epidemiology and molecular analysis of extended-spectrum-β-lactamase-producing Escherichia coli in Nepal: characteristics of sequence types 131 and 648.
The study identified bla CTX-M-15, aac (3)-IIa, aadA1, aadA2, aadA5, qnrB4, qnrS1, aac (6')-Ib-cr, bla OXA-1, bla TEM-1B, bla SHV-12, bla CMY-42, bla DHA-1, mphA, ermB, catA1, catB3, sul1, sul2, dfrA12, dfrA17, dfrA1, dfrA5, tetA, tetB, and tetD as key AMR genes in ESBL-producing E. coli isolates in Nepal, highlighting the prevalence of multidrug resistance.
An outbreak of colistin-resistant Klebsiella pneumoniae carbapenemase-producing Klebsiella pneumoniae in the Netherlands (July to December 2013), with inter-institutional spread.
The study describes an outbreak of colistin-resistant KPC-producing K. pneumoniae ST258 in the Netherlands, highlighting the presence of multiple resistance genes including blaKPC-2, blaSHV-12, and various other AMR genes.
Insight into the mobilome of Aeromonas strains.
The study characterizes various antibiotic resistance genes (ARG) in Aeromonas strains, highlighting the presence of beta-lactamases, aminoglycoside-modifying enzymes, tetracycline resistance genes, and others. These genes are often located on plasmids and contribute to multidrug resistance.
Virulence and antimicrobial resistance factors of Enterococcusspp. isolated from fecal samples from piggery farms in Eastern Cape, South Africa.
The study identified vancomycin resistance genes (vanB, vanC1, vanC2/3), erythromycin resistance gene (ermB), and streptomycin resistance gene (strA) in Enterococcus spp. isolated from pig fecal samples. High levels of multidrug resistance were observed, with resistance to vancomycin, erythromycin, and streptomycin being particularly prevalent.
Genomic and Functional Portrait of a Highly Virulent, CTX-M-15-Producing H30-Rx Subclone of Escherichia coli Sequence Type 131.
The study identifies the CTX-M-15 beta-lactamase gene and other resistance genes such as strA, strB, and aac(3)-IIC in the H30-Rx subclone of E. coli ST131, highlighting its multidrug-resistant nature.
Variability in gene cassette patterns of class 1 and 2 integrons associated with multi drug resistance patterns in Staphylococcus aureus clinical isolates in Tehran-Iran.
The study identified various resistance gene cassettes within class 1 and 2 integrons in Staphylococcus aureus isolates, including aadB, aadA2, dhfrA1, dhfrA11, aacA4, blaoxa2, sat2, catB3, and cmlA6, which confer resistance to aminoglycosides, trimethoprim, beta-lactams, and chloramphenicol.
Antimicrobial Susceptibility of Bordetella bronchiseptica Isolates from Swine and Companion Animals and Detection of Resistance Genes.
The study identified several AMR genes in Bordetella bronchiseptica isolates, including blaBOR-1, blaOXA, strA, strB, sul1, sul2, dfrA7, and tet(A). These genes confer resistance to various antibiotics such as ampicillin, streptomycin, trimethoprim/sulfamethoxazole, and tetracycline.
Abundance of Antibiotic Resistance Genes in Bacteriophage following Soil Fertilization with Dairy Manure or Municipal Biosolids, and Evidence for Potential Transduction.
The study identified antibiotic resistance genes (ARGs) in bacteriophage and bacterial fractions of agricultural soil, demonstrating that soilborne bacteriophage represents a reservoir of antibiotic resistance and that bacteriophage could play a significant role in the horizontal transfer of resistance genes in agricultural soil microbiomes.
Draft Genome Sequence of a Pathogenic O86:H25 Sequence Type 57 Escherichia coli Strain Isolated from Poultry and Carrying 12 Acquired Antibiotic Resistance Genes.
The study reports the draft genome sequence of an E. coli strain carrying 12 acquired antibiotic resistance genes, including beta-lactamases, aminoglycoside modifying enzymes, sulfonamide resistance, trimethoprim resistance, tetracycline resistance, and streptothricin resistance.
Multiple antibiotic resistances among Shiga toxin producing Escherichia coli O157 in feces of dairy cattle farms in Eastern Cape of South Africa.
The study identified multiple antibiotic resistance genes in Shiga toxin-producing Escherichia coli O157 isolates from dairy cattle farms in South Africa, including blaampC, blacmy, blactxm, blatem, tetA, and strA.
Genomic and Functional Characterization of qnr-Encoding Plasmids from Municipal Wastewater Biosolid Klebsiella pneumoniae Isolates.
The study identified two types of plasmids harboring qnr genes in Klebsiella pneumoniae isolates from municipal wastewater biosolids. One plasmid, pKPSH-11XL, was a large multidrug-resistant IncF plasmid containing qnrB, beta-lactamase genes, tetracycline resistance genes, aminoglycoside resistance genes, and chloramphenicol resistance genes. Another group of smaller plasmids contained qnrS and other resistance genes.
Non-Typhoidal Salmonella in poultry meat and diarrhoeic patients: prevalence, antibiogram, virulotyping, molecular detection and sequencing of class I integrons in multidrug resistant strains.
The study identified several AMR genes, including aac(3)-Id, aadA2, aadA4, aadA7, dfrA15, lnuF, sat, and estX, in multidrug-resistant Salmonella strains isolated from poultry meat and diarrheic patients in Egypt.
Apramycin treatment affects selection and spread of a multidrug-resistant Escherichia coli strain able to colonize the human gut in the intestinal microbiota of pigs.
The study identifies multiple AMR genes in the multidrug-resistant E. coli strain 912, including aac(3)-IV, blaTEM-1, sul2, aph(4), tet(X), and strA/B, which confer resistance to various antibiotics such as gentamicin, apramycin, sulfonamides, aminoglycosides, tetracyclines, and streptomycin.
Identification and antimicrobial resistance prevalence of pathogenic Escherichia coli strains from treated wastewater effluents in Eastern Cape, South Africa.
The study identified several AMR genes in E. coli isolates from wastewater effluents, including strA, aadA, catI, cmlA1, blaTEM, and various tetracycline resistance genes (tetA, tetB, tetC, tetD, tetK, tetM). These genes conferred resistance to multiple antibiotics such as streptomycin, gentamicin, chloramphenicol, ampicillin, and tetracycline.
Comparative Genomics of Two ST 195 Carbapenem-Resistant Acinetobacter baumannii with Different Susceptibility to Polymyxin Revealed Underlying Resistance Mechanism.
The study identified blaOXA-23 and blaAmpC genes contributing to carbapenem and extended-spectrum cephalosporin resistance, and mutations in pmrA, pmrB, lpxD, lpxC, and lpsB genes linked to polymyxin resistance in A. baumannii AC30.
Comparative Genomic Analysis of Mannheimia haemolytica from Bovine Sources.
The study identified a bla ROB-1 gene in an integrative conjugative element (ICE) of M. haemolytica, which had a single nucleotide substitution leading to a non-functional gene and sensitivity to ampicillin.
Carriage of Extended-Spectrum Beta-Lactamase-Plasmids Does Not Reduce Fitness but Enhances Virulence in Some Strains of Pandemic E. coli Lineages.
The study found that ESBL-plasmid carriage does not reduce fitness but enhances virulence in some strains of pandemic E. coli lineages. It identified several AMR genes on the ESBL-plasmids, including beta-lactamases (blaCTX-M-15, blaCTX-M-27, blaCTX-M-14), tetracycline resistance genes (tetA, tetR), aminoglycoside resistance genes (aadA, aac(6')-Ib-cr), chloramphenicol resistance gene (catB4), sulfonamide resistance gene (sul2), streptomycin resistance genes (strA, strB), dihydrofolate reductase genes (dhfrVII, dfrA17), and aminoglycoside phosphotransferase gene (aph(3')-Ia). Non-antibiotic resistance genes such as finO, traT, icc, yfaX, yihA, and hha were also identified.
Antibiotic Resistance, Core-Genome and Protein Expression in IncHI1 Plasmids in Salmonella Typhimurium.
The study identified multiple antibiotic resistance genes in IncHI1 plasmids of Salmonella Typhimurium, including tet(B), tet(A), blaTEM, strA, strB, sul2, aadA, dfrA, catA1, aphA1a, and aad(3)IId, which confer resistance to various antibiotics such as tetracycline, beta-lactam, streptomycin, sulfonamide, aminoglycoside, chloramphenicol, and trimethoprim.
SSTAR, a Stand-Alone Easy-To-Use Antimicrobial Resistance Gene Predictor.
The study presents SSTAR, a software tool for identifying antimicrobial resistance (AR) genes from whole-genome sequencing data. It detects known AR genes and potential new variants, including truncated forms. The tool was applied to analyze resistance genes in Klebsiella pneumoniae ST437 and Escherichia coli ST44, revealing various beta-lactamases, aminoglycoside resistance genes, and porin mutations contributing to resistance.
SSTAR, a Stand-Alone Easy-To-Use Antimicrobial Resistance Gene Predictor.
The study presents SSTAR, a software tool for identifying antimicrobial resistance (AR) genes from whole-genome sequencing data. It detects known AR genes and potential new variants, including truncated forms. The tool was applied to analyze resistance genes in Klebsiella pneumoniae ST437 and Escherichia coli ST44, revealing various beta-lactamases, aminoglycoside resistance genes, and porin mutations contributing to resistance.
Whole-Genome Sequencing for Detecting Antimicrobial Resistance in Nontyphoidal Salmonella.
The study identified 65 unique resistance genes in nontyphoidal Salmonella, including bla CTX-M1 and bla SHV2a, which were first reported in retail meat isolates in the United States. The research highlights the effectiveness of whole-genome sequencing in detecting antimicrobial resistance genes and correlating them with phenotypic resistance.
Whole-Genome Sequencing for Detecting Antimicrobial Resistance in Nontyphoidal Salmonella.
The study identified 65 unique resistance genes in nontyphoidal Salmonella, including bla CTX-M1 and bla SHV2a, which were first reported in retail meat isolates in the United States. The research highlights the effectiveness of whole-genome sequencing in detecting antimicrobial resistance genes and correlating them with phenotypic resistance.
First Occurrence of OXA-72-Producing Acinetobacter baumannii in Serbia.
The study reports the first occurrence of OXA-72-producing Acinetobacter baumannii in Serbia, highlighting the presence of multiple AMR genes including blaOXA-72, aadA2, strA, strB, aphA6, armA, blaADC-25, and blaOXA-66, along with fluoroquinolone resistance mutations in gyrA, parC, and parE.
Streaming algorithms for identification of pathogens and antibiotic resistance potential from real-time MinION(TM) sequencing.
The study presents a real-time analysis framework for MinION sequencing data, demonstrating the ability to identify pathogens and antibiotic resistance genes within a few hours of sequencing. Key resistance genes identified include blaSHV, mphA, strA, strB, blaTEM, sul2, blaOXA, aac3, aac6, blaCMY, blaCFE, blaLAT, blaBIL, QnrB, aadA, oqxA, tetA, oqxB, rmtC, sul1, sul3, fosA, blaNDM, oqxA, blaSHV, oqxB, aadB, sul1, sul3, blaOXA, blaOKP, fosA, blaSHV, blaOKP, blaLEN, oqxA, and oqxB.
Draft Genome Sequence of Salmonella enterica subsp. enterica Serovar Bardo Strain CRJJGF_00099 (Phylum Gammaproteobacteria).
The study reports the identification of several AMR genes in a multidrug-resistant Salmonella enterica subsp. enterica serovar Bardo strain, including strA, strB, cmy-94, floR, sulII, tet(A), and aac6-Iy.
Carbapenem Resistance in Clonally Distinct Clinical Strains of Vibrio fluvialis Isolated from Diarrheal Samples.
The study identifies the bla NDM-1 gene as a major cause of carbapenem resistance in Vibrio fluvialis isolates from Kolkata, India. Several additional resistance genes, including aadA1, aadB, aac(6')-Ib-cr, sul1, sul3, floR, bla OXA-1, bla OXA-7, bla OXA-9, bla TEM-9, bla CTX-M-3, strA, and tetB, were also characterized.
Architecture of Class 1, 2, and 3 Integrons from Gram Negative Bacteria Recovered among Fruits and Vegetables.
The study identified several AMR genes in Gram-negative bacteria from fresh produce, including mcr-1, qnrA1, blaGES-11, mphA, and oqxAB, highlighting the presence of mobile genetic elements and clinically relevant resistance genes.
Isolation and plasmid characterization of carbapenemase (IMP-4) producing Salmonella enterica Typhimurium from cats.
The study identifies the blaIMP-4 gene in Salmonella enterica Typhimurium from cats, which confers resistance to carbapenems. The gene is part of a multidrug-resistant IncHI2 plasmid carrying various resistance genes.
Antimicrobial Susceptibility of Autochthonous Aquatic Vibrio cholerae in Haiti.
The study identified several AMR genes in environmental isolates of Vibrio cholerae non-O1/non-O139 in Haiti, including strA, strB, sul1, sul2, ermA, ermB, and mefA, which confer resistance to streptomycin, sulfonamide, and erythromycin.
Comparative Genome Analysis of Extended-Spectrum-β-Lactamase-Producing Escherichia coli Sequence Type 131 Strains from Nepal and Japan.
The study identified multiple AMR genes, including blaCTX-M-15, blaOXA-1, aac(6')-Ib-cr, tet(A), mphA, strA, strB, aadA5, sul1, sul2, dfrA12, dfrA17, catA1, and catB3, in ESBL-producing E. coli ST131 isolates from Nepal and Japan. These genes conferred resistance to various antibiotics, including β-lactams, aminoglycosides, tetracyclines, macrolides, sulfonamides, and chloramphenicol.
Genomic signatures of Mannheimia haemolytica that associate with the lungs of cattle with respiratory disease, an integrative conjugative element, and antibiotic resistance genes.
The study identifies multiple antibiotic resistance genes in Mannheimia haemolytica, particularly in genotype 2, subtype 2b isolates, which are associated with the lungs of cattle with respiratory disease and contain various combinations of resistance genes.
Comprehensive Genome Analysis of Carbapenemase-Producing Enterobacter spp.: New Insights into Phylogeny, Population Structure, and Resistance Mechanisms.
The study identifies multiple carbapenemase genes (bla KPC-2, bla KPC-3, bla KPC-4, and bla NDM-1) and other resistance genes (such as qnrB19, qnrB2, qnrS1, bla TEM-1A, bla TEM-1B, bla OXA-9, bla SHV-12, aadA2, aac(6')-Ib, aac(6')-Ib-cr, aph(3')-Ia, aph(3')-Ic, strA, strB, sul1, sul2, dfrA14, dfrA18, mph(A), catB3, arr-3, and tet(D)) in carbapenem-resistant Enterobacter spp. These genes are primarily located on plasmids and contribute to multidrug resistance.
Comprehensive Genome Analysis of Carbapenemase-Producing Enterobacter spp.: New Insights into Phylogeny, Population Structure, and Resistance Mechanisms.
The study identifies multiple carbapenemase genes (bla KPC-2, bla KPC-3, bla KPC-4, and bla NDM-1) and other resistance genes (such as qnrB19, qnrB2, qnrS1, bla TEM-1A, bla TEM-1B, bla OXA-9, bla SHV-12, aadA2, aac(6')-Ib, aac(6')-Ib-cr, aph(3')-Ia, aph(3')-Ic, strA, strB, sul1, sul2, dfrA14, dfrA18, mph(A), catB3, arr-3, and tet(D)) in carbapenem-resistant Enterobacter spp. These genes are primarily located on plasmids and contribute to multidrug resistance.
Whole-Genome Analysis of Antimicrobial-Resistant and Extraintestinal Pathogenic Escherichia coli in River Water.
The study identified numerous antimicrobial resistance genes in Escherichia coli isolates from river water, highlighting the presence of multidrug-resistant and extraintestinal pathogenic strains. Key resistance genes included blaTEM-1, aac(3)-IId, qnrB7, and others.
Whole-Genome Analysis of Antimicrobial-Resistant and Extraintestinal Pathogenic Escherichia coli in River Water.
The study identified numerous antimicrobial resistance genes in Escherichia coli isolates from river water, highlighting the presence of multidrug-resistant and extraintestinal pathogenic strains. Key resistance genes included blaTEM-1, aac(3)-IId, qnrB7, and others.
Draft Genome Sequences of Pandrug-Resistant Serratia marcescens Clinical Isolates Harboring blaNDM-1.
The study reports the draft genome sequences of two pandrug-resistant Serratia marcescens clinical isolates carrying multiple antibiotic resistance genes, including blaNDM-1, blaSHV-12, blaTEM-1B, blaCMY-6, sul1, sul2, rmtC, aacA4, aac(6')Ib-c, strA, strB, dfrA18, qnrA1, catA2, aac(6')-Ic, tet(41), and ampC.
Panel strain of Klebsiella pneumoniae for beta-lactam antibiotic evaluation: their phenotypic and genotypic characterization.
The study characterizes various AMR genes and mutations in K. pneumoniae panel strains, including beta-lactamases (bla SHV-11, bla TEM-1, bla CTX-M15, bla OXA-1, bla SHV-12, bla SHV-187, bla SHV-158, bla DHA-1, bla CMY-2), aminoglycoside modifying enzymes (aac(6')-Ib, strA, strB, aadA1, aadA2), quinolone resistance genes (qnrB66, qnrB4, oqxA, oqxB), tetracycline resistance (tet(A)), trimethoprim resistance (dfrA14), sulfonamide resistance (sul1, sul2), and porin genes (OmpK35, OmpK36).
Epidemiological, molecular characterization and antibiotic resistance of Salmonella enterica serovars isolated from chicken farms in Egypt.
The study identified various AMR genes in Salmonella enterica serovars isolated from chicken farms in Egypt, including blaTEM, aadA2, floR, cat1, sul1, sul3, tetC, tetA, and intI, which confer resistance to ampicillin, streptomycin, chloramphenicol, sulfamethoxazole, tetracycline, and multiple antibiotics.
Carbapenem-resistance and pathogenicity of bovine Acinetobacter indicus-like isolates.
The study identifies carbapenem-resistant Acinetobacter indicus-like isolates from cattle carrying the blaOXA-23 gene, along with various other AMR genes such as aac(3)-IIa, strA/B, aph(3')-Ic, sul2, floR, tet(A), tet(Y), aadA1, aadB, sul1, and tet(X).
Evolution and Epidemiology of Multidrug-Resistant Klebsiella pneumoniae in the United Kingdom and Ireland.
The study identifies several AMR genes and mutations associated with multidrug-resistant Klebsiella pneumoniae in the UK and Ireland, including beta-lactamases, aminoglycoside-modifying enzymes, tetracycline efflux pumps, and mutations in gyrB contributing to fluoroquinolone resistance.
Identification of a novel sequence type of Escherichia coli as the causative agent of pyelonephritis and bloodstream infection.
The study identifies a novel sequence type of Escherichia coli (ST-458) responsible for pyelonephritis and bloodstream infection, carrying multiple antibiotic resistance genes and mutations associated with resistance to fluoroquinolones, aminoglycosides, sulfonamides, and beta-lactams.
Whole-Genome Sequencing of Drug-Resistant Salmonella enterica Isolates from Dairy Cattle and Humans in New York and Washington States Reveals Source and Geographic Associations.
The study identified several AMR genes and mutations in Salmonella enterica isolates from dairy cattle and humans in New York and Washington States, highlighting the role of geographic and source-specific factors in AMR dissemination.
Genomic Analysis of Factors Associated with Low Prevalence of Antibiotic Resistance in Extraintestinal Pathogenic Escherichia coli Sequence Type 95 Strains.
The study identifies several AMR genes in ST95 E. coli strains, including blaTEM-1, blaCTX-M14, aadA1, aadA2, aadA5, aac3, strA, strB, tetA, tetB, tetD, sul1, sul2, dfrA5, dfrA12, dfrA17, mphA, and catA1, which confer resistance to various antibiotics such as ampicillin, cephalothin, streptomycin, tetracycline, sulfamethoxazole, trimethoprim, azithromycin, and chloramphenicol.
Genomic Analysis of Factors Associated with Low Prevalence of Antibiotic Resistance in Extraintestinal Pathogenic Escherichia coli Sequence Type 95 Strains.
The study identifies several AMR genes in ST95 E. coli strains, including blaTEM-1, blaCTX-M14, aadA1, aadA2, aadA5, aac3, strA, strB, tetA, tetB, tetD, sul1, sul2, dfrA5, dfrA12, dfrA17, mphA, and catA1, which confer resistance to various antibiotics such as ampicillin, cephalothin, streptomycin, tetracycline, sulfamethoxazole, trimethoprim, azithromycin, and chloramphenicol.
Distribution of Integrons and Phylogenetic Groups among Enteropathogenic Escherichia coli Isolates from Children <5 Years of Age in Delhi, India.
The study identified various AMR genes including dfrA1, dfrA7, dfrA12, aadA1, aadA2, sul1, tetA, aacC1, TEM, SHV, CTX-M, OXA, NDM-1, IMP, VIM, ACT, DHA, and CMY in E. coli isolates from children in Delhi, India. These genes were associated with resistance to multiple antibiotics such as trimethoprim, streptomycin, sulfonamides, tetracycline, gentamicin, and various beta-lactams.
Genome sequence of Shigella flexneri strain SP1, a diarrheal isolate that encodes an extended-spectrum β-lactamase (ESBL).
The study identifies the presence of multiple antibiotic resistance genes in the Shigella flexneri strain SP1, including blaCTX-M-14, blaOXA-1, aadA24, strA, strB, catA1, tetD, sul2, and dfrA1, which contribute to its multidrug-resistant phenotype.
Biofilm Formation Potential of Heat-Resistant Escherichia coli Dairy Isolates and the Complete Genome of Multidrug-Resistant, Heat-Resistant Strain FAM21845.
The study identified multiple antimicrobial resistance genes in the multidrug-resistant, heat-resistant E. coli strain FAM21845, including beta-lactamase blaTEM-1, aminoglycoside resistance genes strA, strB, aadA1, aph(3')-Ic, aph(4)-Ia, aac(3)-IVa, sulfonamide resistance gene sul1, trimethoprim resistance gene dfrA1, tetracycline resistance gene tet(B), disinfectant resistance gene qacEΔ1, and biofilm-related genes mrkABCDF. Additionally, the strain carried genes for resistance to arsenic, silver, and copper.
Genomic Analysis of Multidrug-Resistant Escherichia coli from North Carolina Community Hospitals: Ongoing Circulation of CTX-M-Producing ST131-H30Rx and ST131-H30R1 Strains.
The study identified multiple AMR genes and mutations in multidrug-resistant E. coli isolates from North Carolina community hospitals, including bla CTX-M-15, bla CTX-M-14, aac(6′)-Ib-cr, qnrS1, and mutations in gyrA, parC, and parE that confer resistance to various antibiotics.
Characterization of a blaNDM‑1‑harboring plasmid from a Salmonella enterica clinical isolate in China.
The study characterizes a blaNDM-1-harboring plasmid from a Salmonella enterica clinical isolate in China, identifying multiple resistance genes including blaNDM-1, blaCMY-6, dfrA12, aadA2, rmtC, qacEΔ1, sul1, and bleMBL.
Characterization of the Complete Nucleotide Sequences of IncA/C2 Plasmids Carrying In809-Like Integrons from Enterobacteriaceae Isolates of Wildlife Origin.
The study characterized IncA/C2 plasmids carrying In809-like integrons from Enterobacteriaceae isolates of wildlife origin, identifying several AMR genes including blaIMP-4, blaIMP-26, blaIMP-38, sul2, floR, aac(3)-IId, qnrA1, arr-3, dfrA12, aphA1, aadA16, aadA2, blaOXA-1, blaTEM-1, and blaDHA-1.
Whole-Genome Sequencing and Concordance Between Antimicrobial Susceptibility Genotypes and Phenotypes of Bacterial Isolates Associated with Bovine Respiratory Disease.
The study identified several antimicrobial resistance genes in bacterial isolates associated with bovine respiratory disease, including ermF, dfrA14, tetH, sul2, floR, aph3-Ia, ROB-1, and cat2. These genes conferred resistance to various antibiotics such as macrolides, tetracyclines, sulfonamides, phenicols, aminoglycosides, and beta-lactams.
Horizontal Dissemination of Antimicrobial Resistance Determinants in Multiple Salmonella Serotypes following Isolation from the Commercial Swine Operation Environment after Manure Application.
The study identified various antimicrobial resistance genes, including bla_CMY-2, bla_TEM, aadA2, tet(A), tet(B), sul1, and sul2, in multiple Salmonella serotypes isolated from swine farm environments. These genes were found on plasmids and contributed to resistance against beta-lactams, aminoglycosides, tetracyclines, and sulfonamides.
Comparative Sequence Analysis of Multidrug-Resistant IncA/C Plasmids from Salmonella enterica.
The study identified multiple antimicrobial resistance genes on IncA/C plasmids from various Salmonella serovars, including bla_cmy-2, bla_tem-1, strA, strB, aadB, aph(3')-Ia, tetA, floR, cmlA, sul1, sul2, dfra12, quacE, sugE, merA, merB, merC, merD, and merE, which contribute to multidrug resistance.
Rapid Nanopore Sequencing of Plasmids and Resistance Gene Detection in Clinical Isolates.
The study demonstrates the feasibility of rapid nanopore sequencing for detecting plasmid-borne antimicrobial resistance (AMR) genes in clinical isolates. It identifies several AMR genes, including beta-lactamases, aminoglycoside-modifying enzymes, sulfonamide resistance genes, tetracycline resistance genes, macrolide resistance genes, and phenicol resistance genes, in both Escherichia coli and Klebsiella pneumoniae isolates.
Rapid Nanopore Sequencing of Plasmids and Resistance Gene Detection in Clinical Isolates.
The study demonstrates the feasibility of rapid nanopore sequencing for detecting plasmid-borne antimicrobial resistance (AMR) genes in clinical isolates. It identifies several AMR genes, including beta-lactamases, aminoglycoside-modifying enzymes, sulfonamide resistance genes, tetracycline resistance genes, macrolide resistance genes, and phenicol resistance genes, in both Escherichia coli and Klebsiella pneumoniae isolates.
Characterization of Four Multidrug Resistance Plasmids Captured from the Sediments of an Urban Coastal Wetland.
Four multidrug resistance plasmids were captured from the sediments of an urban coastal wetland. These plasmids carried various resistance genes, including beta-lactamases, tetracycline resistance genes, sulfonamide resistance genes, and others, conferring resistance to multiple antibiotics.
Extensively Drug-Resistant Escherichia coli Sequence Type 1642 Carrying an IncX3 Plasmid Containing the blaKPC-2 Gene Associated with Transposon Tn4401a.
The study identifies several AMR genes in an extensively drug-resistant E. coli ST1642 isolate, including blaKPC-2, blaSHV-11, blaTEM-1, aadA5, strA, strB, aac(3)-IId, mph(A), sul1, sul2, tet(B), dfrA17, and qnrS1, which contribute to resistance against multiple antibiotics.
ARIBA: Rapid identification of antimicrobial resistance genes and variants from whole-genome sequencing data
The paper presents ARIBA, a tool for identifying antimicrobial resistance genes and mutations from sequencing data. It evaluates the performance of ARIBA on three datasets, demonstrating its accuracy and efficiency in detecting resistance genes and mutations in Enterococcus faecium, Shigella sonnei, and Neisseria gonorrhoeae.
In vivo selection of a multidrug-resistant Aeromonas salmonicida during medicinal leech therapy.
The study identifies 13 antibiotic resistance genes in a multidrug-resistant Aeromonas salmonicida strain, including the ESBL CTX-M-3, TEM-1, and the unusual β-lactamase SCO-1, along with other resistance mechanisms such as aminoglycoside modification, sulfonamide resistance, tetracycline efflux, and chloramphenicol acetylation.
Metagenomics Reveals the Impact of Wastewater Treatment Plants on the Dispersal of Microorganisms and Genes in Aquatic Sediments.
The study identifies several antibiotic resistance genes (ARGs) in wastewater treatment plant (WWTP) effluents and lake sediments, highlighting the influence of WWTPs on the dispersal of these genes in aquatic environments. Key ARGs include strA, acrB, adeJ, mexB, and smeE, which are associated with aminoglycoside and multidrug resistance.
Porcine commensal Escherichia coli: a reservoir for class 1 integrons associated with IS26.
The study identified 17 antimicrobial resistance genes (ARGs) in 103 class 1 integron-positive Escherichia coli strains from porcine feces, highlighting the prevalence of multidrug-resistant commensal E. coli in pigs and their potential role in the dissemination of resistance genes.
High Prevalence of CTX-M-15-Type ESBL-Producing E. coli from Migratory Avian Species in Pakistan.
The study identified a high prevalence of CTX-M-15-type ESBL-producing E. coli in migratory avian species in Pakistan, highlighting the role of wild birds as reservoirs of multidrug-resistant bacteria and the potential for horizontal gene transfer of resistance determinants.
High Prevalence of CTX-M-15-Type ESBL-Producing E. coli from Migratory Avian Species in Pakistan.
The study identified a high prevalence of CTX-M-15-type ESBL-producing E. coli in migratory avian species in Pakistan, highlighting the role of wild birds as reservoirs of multidrug-resistant bacteria and the potential for horizontal gene transfer of resistance determinants.
Complete Genome Sequence of a bla(CTX-M-1)-Harboring Escherichia coli Isolate Recovered from Cattle in Germany.
The study reports the complete genome sequence of an Escherichia coli isolate carrying the bla(CTX-M-1) gene, along with other resistance genes including mph(A), sul2, dfrA5, strA, and strB, indicating multidrug resistance.
pSTM6-275, a Conjugative IncHI2 Plasmid of Salmonella enterica That Confers Antibiotic and Heavy-Metal Resistance under Changing Physiological Conditions.
The IncHI2 plasmid pSTM6-275 from Salmonella enterica carries multiple antibiotic and heavy-metal resistance genes, including blaTEM, strA, strB, sul3, aadA1, aadA2, cmlA, aphA2, tetA, mejB, silESRCFBAGP, and pcoGE1ABCDRSE2, which confer resistance to various antibiotics and metals. The plasmid exhibits temperature-dependent resistance to silver and copper, highlighting its adaptability under changing physiological conditions.
pSTM6-275, a Conjugative IncHI2 Plasmid of Salmonella enterica That Confers Antibiotic and Heavy-Metal Resistance under Changing Physiological Conditions.
The IncHI2 plasmid pSTM6-275 from Salmonella enterica carries multiple antibiotic and heavy-metal resistance genes, including blaTEM, strA, strB, sul3, aadA1, aadA2, cmlA, aphA2, tetA, mejB, silESRCFBAGP, and pcoGE1ABCDRSE2, which confer resistance to various antibiotics and metals. The plasmid exhibits temperature-dependent resistance to silver and copper, highlighting its adaptability under changing physiological conditions.
Impact of Wastewater Treatment on the Prevalence of Integrons and the Genetic Diversity of Integron Gene Cassettes.
The study identified various antibiotic resistance genes within integron gene cassettes in wastewater treatment plants, including aadA1, aadA2, aadA5, blaOXA-1, blaOXA-10, blaOXA-101, blaOXA-129, blaOXA-21, blaOXA-28, catB8, dfrA14, erm, qacE2, sul1, tet, orfD, and orfA, which confer resistance to aminoglycosides, beta-lactams, chloramphenicol, trimethoprim, sulfonamides, tetracyclines, and quaternary ammonium compounds.
Clinically Relevant ESBL-Producing K. pneumoniae ST307 and E. coli ST38 in an Urban West African Rat Population.
The study identifies clinically relevant ESBL-producing K. pneumoniae ST307 and E. coli ST38 in an urban West African rat population, highlighting the presence of multidrug-resistant strains carrying various resistance genes such as blaCTX-M-15, blaCTX-M-14, blaCTX-M-9, and others.
Genome Sequencing of Extended-Spectrum β-Lactamase (ESBL)-Producing Klebsiella pneumoniae Isolated from Pigs and Abattoir Workers in Cameroon.
The study identified multiple antibiotic resistance genes in ESBL-producing K. pneumoniae isolates from pigs and abattoir workers in Cameroon, including bla CTX-M-15, bla TEM-1B, bla SHV-28, and others, highlighting the presence of multidrug-resistant strains and their potential for zoonotic transmission.
Prediction of Phenotypic Antimicrobial Resistance Profiles From Whole Genome Sequences of Non-typhoidal Salmonella enterica.
The study identified various AMR genes and mutations in non-typhoidal Salmonella enterica, including blaTEM-1, strA-strB, sul2, tet(A), qnrS1, aadA2, aadA17, floR, cmlA1, aac(3)-Id, aac(3)-IIa, dfrA12, dfrA1, dfrA14, blaCTX-M-9, blaCTX-M-55, blaSHV-12, blaPSE-1/blaCARB-2, and blaCMY-2, along with mutations in gyrA and parC associated with ciprofloxacin resistance.
Serotype Diversity and Antimicrobial Resistance among Salmonella enterica Isolates from Patients at an Equine Referral Hospital.
The study identified various AMR genes in Salmonella enterica isolates from equine patients, including beta-lactamases, aminoglycoside modifying enzymes, and genes conferring resistance to tetracyclines, macrolides, and other antibiotics.
Serotype Diversity and Antimicrobial Resistance among Salmonella enterica Isolates from Patients at an Equine Referral Hospital.
The study identified various AMR genes in Salmonella enterica isolates from equine patients, including beta-lactamases, aminoglycoside modifying enzymes, and genes conferring resistance to tetracyclines, macrolides, and other antibiotics.
Laboratory and molecular surveillance of paediatric typhoidal Salmonella in Nepal: Antimicrobial resistance and implications for vaccine policy.
The study identified multiple AMR genes and mutations in Salmonella Typhi and Salmonella Paratyphi A isolates from Nepal, including gyrA and parC mutations associated with fluoroquinolone resistance, and acquired AMR genes such as catA1, dfrA7, sul1, sul2, strA, strB, and blaTEM-1 associated with multidrug resistance.
An outbreak of a rare Shiga-toxin-producing Escherichia coli serotype (O117:H7) among men who have sex with men.
The study identified several AMR genes and mutations in STEC O117:H7 isolates, including the azithromycin resistance gene mphA, aadA1, aadA2, aadA5, blaTEM-1B, blaTEM-1C, dfrA1, dfrA12, dfrA14, dfrA, dfrA5, ermB, strA, strB, sul1, sul2, tet(A), tet(B), qnrs1, and a mutation in gyrA (S83L) associated with fluoroquinolone resistance.
An outbreak of a rare Shiga-toxin-producing Escherichia coli serotype (O117:H7) among men who have sex with men.
The study identified several AMR genes and mutations in STEC O117:H7 isolates, including the azithromycin resistance gene mphA, aadA1, aadA2, aadA5, blaTEM-1B, blaTEM-1C, dfrA1, dfrA12, dfrA14, dfrA, dfrA5, ermB, strA, strB, sul1, sul2, tet(A), tet(B), qnrs1, and a mutation in gyrA (S83L) associated with fluoroquinolone resistance.
Polyphyletic Nature of Salmonella enterica Serotype Derby and Lineage-Specific Host-Association Revealed by Genome-Wide Analysis.
The study identified AMR genes aadA2, sul1, and tetA in Salmonella enterica serovar Derby strains, with a multidrug-resistant profile STR-SSS-TET in certain lineages.
Distribution and Genetic Characteristics of SXT/R391 Integrative Conjugative Elements in Shewanella spp. From China.
The study identified the SXT/R391 integrative conjugative element ICE Sup CHN110003 in Shewanella upenei strains, which carries antibiotic resistance genes floR, strA, strB, and sul2, conferring resistance to chloramphenicol, streptomycin, and sulfamethoxazole.
The Use of a Combined Bioinformatics Approach to Locate Antibiotic Resistance Genes on Plasmids From Whole Genome Sequences of Salmonella enterica Serovars From Humans in Ghana.
The study identified several AMR genes in Salmonella isolates from Ghana, including blaTEM-1B, blaTEM-52B, blaCTX-M-15, tet(A), dfrA15, sul1, sul2, catA1, strA, strB, aadA1, catB3, qnrB1, aac(6')Ib-cr, and blaOXA-1. These genes were found on various plasmids, highlighting the diversity of resistance mechanisms in the studied isolates.
Gene cassettes of class I integron-associated with antimicrobial resistance in isolates of Citrobacter spp. with multidrug resistance.
The study identified several gene cassettes associated with antimicrobial resistance in multidrug-resistant Citrobacter isolates, including aadA1, aadA2, dfrA1, dfrA12, dfrA15, dfrA1-aadA1, and dfrA12-orfF-aadA2.
Antimicrobial Resistance in Escherichia coli.
The paper discusses the characterization of various antimicrobial resistance genes in Escherichia coli, including extended-spectrum beta-lactamases (ESBLs), AmpC cephalosporinases, carbapenemases, plasmid-mediated quinolone resistance (PMQR) genes, aminoglycoside-modifying enzymes, fosfomycin resistance genes, and tetracycline resistance genes. These genes confer resistance to multiple classes of antibiotics, highlighting the complex nature of antimicrobial resistance in E. coli.
Evolution and Comparative Genomics of F33:A-:B- Plasmids Carrying bla(CTX-M-55) or bla(CTX-M-65) in Escherichia coli and Klebsiella pneumoniae Isolated from Animals, Food Products, and Humans in China.
The study characterizes F33:A−:B− plasmids carrying various AMR genes such as bla(CTX-M-55), bla(CTX-M-65), fosA3, rmtB, and others in E. coli and K. pneumoniae isolates from diverse sources in China.
Antibiotic resistance gene dynamics in the gut microbiota following amoxicillin-clavulanic acid treatment
The study identified several AMR genes, including aminoglycoside resistance genes (ksgA, strA, strB), beta-lactam resistance genes (blaCARB-4, blaCMY-1, blaCMY-2, blaCTX-M-1, blaCTX-M-12, blaDHA-1, blaOXA-1, blaSHV-1, blaSHV-37, blaSHV-3, blaTEM-1A, blaTEM-1B), and tetracycline resistance genes (tetA, tetB, tetC, tetK, tetL), that were enriched in the gut microbiota of healthy adults following amoxicillin-clavulanic acid treatment.
Superficieibacter electus gen. nov., sp. nov., an Extended-Spectrum β-Lactamase Possessing Member of the Enterobacteriaceae Family, Isolated From Intensive Care Unit Surfaces.
The study identifies multiple antibiotic resistance genes in the newly described species Superficieibacter electus, including beta-lactamases, aminoglycoside modifying enzymes, and others, indicating its ability to resist various antibiotics.
Dynamics of antimicrobial resistance in intestinal Escherichia coli from children in community settings in South Asia and sub-Saharan Africa.
The study identified multiple AMR genes in aEPEC isolates from children in South Asia and sub-Saharan Africa, highlighting the prevalence of resistance to multiple antibiotics, including ampicillin, streptomycin, trimethoprim/sulphamethoxazole, and tetracycline.
Antimicrobial Resistance in Commensal Escherichia coli Isolated from Pigs and Pork Derived from Farms Either Routinely Using or Not Using In-Feed Antimicrobials.
The study identified aadA1, aadA2, aadB, and bla CTX-M-1 as the primary AMR genes in commensal E. coli from pigs and pork, with higher prevalence in farms using in-feed antimicrobials.
Variant O89 O-Antigen of E. coli Is Associated With Group 1 Capsule Loci and Multidrug Resistance.
The study identified a novel O89 O-antigen locus in E. coli strain 26561, which is associated with group 1 capsule (G1C) and multidrug resistance. The strain exhibits a mucoid and viscous phenotype, and possesses multiple AMR genes including blaCTX-M-14, blaTEM-1, aph(3")-Ib, strA, aph(6)-Id, strB, aph(3′)-Ia, sul2, tetA(B), and catA1. Mutations in gyrA (S83L, D87N) and parC (S80I) contribute to quinolone resistance.
Bifidobacterial Dominance of the Gut in Early Life and Acquisition of Antimicrobial Resistance.
High levels of Bifidobacterium in early life are associated with reduced levels of antimicrobial resistance (AMR) in the gut microbiome. Specifically, the gene ermX, encoding a 23S rRNA methyltransferase, was found to be significantly enriched in high-Bifidobacterium samples and is associated with resistance to macrolides, lincosamides, and streptogramin B.
Interplay Between the Phenotype and Genotype, and Efflux Pumps in Drug-Resistant Strains of Riemerella anatipestifer.
The study identified multiple AMR genes and mutations in Riemerella anatipestifer, including aac(6')-Ib, aadA1, aadA2, aadA5, aac(3')-IIc, aac(3')-IV, aph(3')-VII, aph(2')-Ib, bla TEM, bla OXA, tet(A), tet(B), sul1, sul2, sul3, cat2, cmlA, floR, emrF, qnrS, and qnrD. Additionally, mutations in gyrA and parC were found to confer fluoroquinolone resistance.
Draft genome sequence data of a tigecycline-resistant Enterobacter cloacae ST93 clinical strain isolated from bloodstream infection.
The study reports the draft genome sequence of a tigecycline-resistant Enterobacter cloacae ST93 clinical isolate, TREC1, which harbors multiple antimicrobial resistance genes, including those encoding resistance to beta-lactams, aminoglycosides, fluoroquinolones, fosfomycin, macrolides, lincosamides, streptogramin B, phenicols, sulfonamides, trimethoprim, and tetracyclines. The isolate is resistant to all antibiotics tested except colistin.
Genotypic and phenotypic characterization of Salmonella enterica subsp. enterica serovar Typhimurium monophasic variants isolated in Thailand and Japan.
The study identified several antimicrobial resistance genes in Salmonella enterica subsp. enterica serovar Typhimurium monophasic variants, including blaTEM, aadA, strA, strB, tet(A), tet(B), tet(G), sul1, sul2, sul3, and floR, which confer resistance to ampicillin, streptomycin, oxytetracycline, sulfisoxazole, and chloramphenicol.
The Transferable Resistome of Produce.
The study identified multiple tetracycline resistance genes, beta-lactamases, and other resistance determinants in E. coli isolates from produce, highlighting the potential for horizontal gene transfer and the significance of the produce microbiome as a reservoir of antibiotic resistance genes.
Evidence of Illegitimate Recombination Between Two Pasteurellaceae Plasmids Resulting in a Novel Multi-Resistance Replicon, pM3362MDR, in Actinobacillus pleuropneumoniae.
The study identifies a novel multi-resistance plasmid, pM3362MDR, in Actinobacillus pleuropneumoniae, which carries the tetracycline resistance gene tet(B), as well as blaROB-1, sul2, and strA. The plasmid arose through illegitimate recombination between pTetHS016 and pOV.
Salmonella enterica Serovar Typhi in Bangladesh: Exploration of Genomic Diversity and Antimicrobial Resistance.
The study identified several AMR genes and mutations in S. Typhi isolates from Bangladesh, including blaTEM-1B, blaCTX-M-15, catA1, dfrA7, sul1, sul2, qnrS1, strA, strB, tet(A), tet(B), and mutations in gyrA and parE associated with ciprofloxacin resistance.
Genome sequence analysis of an extensively drug-resistant Acinetobacter baumannii indigo-pigmented strain depicts evidence of increase genome plasticity.
The study identifies multiple antibiotic resistance genes in the extensively drug-resistant Acinetobacter baumannii strain Ab33405, including beta-lactamases, aminoglycoside modifying enzymes, and efflux pumps, highlighting the genetic basis of its multidrug resistance.
Emerging Multidrug-Resistant Hybrid Pathotype Shiga Toxin-Producing Escherichia coli O80 and Related Strains of Clonal Complex 165, Europe.
The study identifies multidrug-resistant hybrid pathotype Shiga toxin-producing E. coli O80 strains belonging to clonal complex 165, which harbor a mosaic plasmid with genes conferring resistance to multiple antibiotics, including beta-lactams, tetracyclines, sulfonamides, trimethoprim, kanamycin, streptomycin, and colistin.
Investigation of a Carbapenemase-producing Acinetobacter baumannii outbreak using whole genome sequencing versus a standard epidemiologic investigation.
The study identified the carbapenemase gene blaOXA-237 and intrinsic blaOXA-66 as responsible for carbapenem resistance in Acinetobacter baumannii. Aminoglycoside resistance was mediated by aadA1, aph(3')-Ia, armA, strA, and strB. Quinolone resistance was due to mutations in GyrA (Ser-83-Leu) and ParC (Ser-80-Leu).
High abundances of class 1 integrase and sulfonamide resistance genes, and characterisation of class 1 integron gene cassettes in four urban wetlands in Nigeria.
The study identified high abundances of class 1 integrase (intI1) and sulfonamide resistance genes (sul1 and sul2) in urban wetlands in Nigeria, along with various gene cassettes in class 1 integrons that confer resistance to trimethoprim, aminoglycosides, rifampicin, and fluoroquinolones.
Complete Genome Sequence of bla (IMP-6)-Positive Metakosakonia sp. MRY16-398 Isolate From the Ascites of a Diverticulitis Patient.
The study identifies the blaIMP-6 gene, along with aacA4'-3, aadA2, and tet(A), as responsible for carbapenem and aminoglycoside resistance in the novel Metakosakonia sp. strain MRY16-398.
Interspecies DNA acquisition by a naturally competent Acinetobacter baumannii strain.
The study shows that Acinetobacter baumannii A118 can acquire antibiotic resistance genes from other species through natural transformation, leading to increased resistance to various antibiotics such as meropenem, imipenem, and sulfamethoxazole.
Multidrug Resistant Uropathogenic Escherichia coli ST405 With a Novel, Composite IS26 Transposon in a Unique Chromosomal Location.
The study identifies a novel composite IS26 transposon, Tn6242, in multidrug-resistant E. coli ST405, carrying resistance genes including dfrA17, aadA5, sul1, mphA, strA, strB, blaTEM-1b, and sul2.
Genomic analysis of Klebsiella pneumoniae isolates from Malawi reveals acquisition of multiple ESBL determinants across diverse lineages.
The study identified multiple ESBL genes, including bla CTX-M-15, several bla SHV, bla TEM-63, and bla OXA-10, along with other AMR genes across diverse lineages of K. pneumoniae isolates from Malawi. No carbapenem resistance genes were detected, but plasmids similar to carbapenem resistance-associated plasmid pNDM-mar were found.
Genomic analysis of Klebsiella pneumoniae isolates from Malawi reveals acquisition of multiple ESBL determinants across diverse lineages.
The study identified multiple ESBL genes, including bla CTX-M-15, several bla SHV, bla TEM-63, and bla OXA-10, along with other AMR genes across diverse lineages of K. pneumoniae isolates from Malawi. No carbapenem resistance genes were detected, but plasmids similar to carbapenem resistance-associated plasmid pNDM-mar were found.
Comparative Genomic Analyses Reveal Core-Genome-Wide Genes Under Positive Selection and Major Regulatory Hubs in Outlier Strains of Pseudomonas aeruginosa.
The study identified genes under positive selection in Pseudomonas aeruginosa outlier strains, including oprD, which is implicated in carbapenem resistance through reduced uptake.
Whole-Genome Sequences of Five Acinetobacter baumannii Strains From a Child With Leukemia M2.
Five multidrug-resistant Acinetobacter baumannii strains from a child with leukemia M2 were characterized. They harbored blaOXA-51 and blaOXA-23 genes, which confer resistance to carbapenems.
Cross-Border Transmission of Salmonella Choleraesuis var. Kunzendorf in European Pigs and Wild Boar: Infection, Genetics, and Evolution.
The study identified multiple antimicrobial resistance genes in Salmonella Choleraesuis isolates, including aadA1, catA1, cmlA1, floR, mph(B), strA, strB, sul1, sul2, sul3, tet(A), tet(B), dfrA1, aph(3')-Ia, lnu(B), and blaTEM-1. These genes conferred resistance to various antibiotics such as streptomycin, chloramphenicol, florfenicol, erythromycin, sulfamethoxazole, tetracycline, trimethoprim, gentamicin, lincomycin, and ampicillin.
Characterisation of antibiotic resistance of Salmonella isolated from dog treats in Japan.
The study identified the presence of antibiotic-resistant Salmonella in dog treats in Japan, including the blaTEM gene, aadA1, aadA2, tetB, floR, catA1, dfrA12, and intI1 genes, indicating multidrug resistance.
Rapid Replacement of Acinetobacter baumannii Strains Accompanied by Changes in Lipooligosaccharide Loci and Resistance Gene Repertoire.
The study identified various AMR genes in clade F strains of Acinetobacter baumannii, including blaOXA-23, aadB, aadA2, aphA6, aacC1, aadA1, and armA, which confer resistance to multiple antibiotics.
First clinical case of KPC-3-producing Klebsiella michiganensis in Europe.
The study reports the first clinical case of a KPC-3-producing Klebsiella michiganensis isolate in Europe, highlighting the emergence of this multidrug-resistant pathogen and the significance of molecular diagnostics in identifying novel resistance mechanisms.
Plasmids of Shigella flexneri serotype 1c strain Y394 provide advantages to bacteria in the host.
The study identifies the multidrug resistance plasmid pNV-Y394 in Shigella flexneri serotype 1c strain Y394, which carries the genes sul2, strA-strB, and tetA, conferring resistance to sulfonamide, streptomycin, and tetracycline, respectively.
Diverse Commensal Escherichia coli Clones and Plasmids Disseminate Antimicrobial Resistance Genes in Domestic Animals and Children in a Semirural Community in Ecuador.
The study identified various antimicrobial resistance (AMR) genes in commensal Escherichia coli isolates from children and domestic animals in a semirural community in Ecuador. These genes included blaTEM-1B, dfrA8, qnrB19, strA, strB, tetA, tetB, sul1, sul2, and others, contributing to resistance against multiple antibiotics such as ampicillin, trimethoprim, tetracycline, and sulfamethoxazole. The research highlights the role of plasmids in disseminating these AMR genes and emphasizes the complexity of AMR transmission in such environments.
Characterization of a carbapenem- and colistin-resistant Enterobacter cloacae carrying Tn6901 in bla (NDM-1) genomic context.
The study characterizes a carbapenem- and colistin-resistant Enterobacter cloacae strain, PIMB10EC27, which carries multiple resistance genes including blaNDM-1, blaSHV-12, and qnrS1, as well as mutations in pmrB and pmrC that may contribute to colistin resistance.
Edwardsiella piscicida: A versatile emerging pathogen of fish.
The study identifies multiple antibiotic resistance genes in Edwardsiella piscicida, including tetA, tetR, strA, strB, sulII, and catA3, which confer resistance to tetracycline, streptomycin, sulfonamides, and chloramphenicol.
Antibiotic Resistance of E. coli Isolated From a Constructed Wetland Dominated by a Crow Roost, With Emphasis on ESBL and AmpC Containing E. coli.
The study identified bla ctx-M and bla cmy-2 genes as major contributors to extended-spectrum beta-lactamase (ESBL) and AmpC beta-lactamase resistance in E. coli isolates from a constructed wetland dominated by a crow roost. Tetracycline resistance was primarily mediated by tet (A), tet (B), and tet (M), while streptomycin resistance was linked to strA, strB, and aadA. Sulfamethoxazole/trimethoprim resistance was associated with the sul1 gene.
Genomic Features of High-Priority Salmonella enterica Serovars Circulating in the Food Production Chain, Brazil, 2000-2016.
The study identified several AMR genes in Salmonella enterica isolates from Brazil, including qnrE1, qnrB19, qnrS1, blaCTX-M-2, blaCTX-M-8, blaCMY-2, aadA1, aadA2, aac(3)-IVa, aac(3)-IIa, aac(6')-Ib, floR, sul1, sul2, tet(A), tet(B), strA, strB, drfA1, inu(F), qacEdelta1, and fosA7. These genes conferred resistance to various antibiotics such as fluoroquinolones, beta-lactams, aminoglycosides, sulfonamides, tetracyclines, chloramphenicol, trimethoprim, macrolides, quaternary ammonium compounds, and fosfomycin.
Genomic Features of High-Priority Salmonella enterica Serovars Circulating in the Food Production Chain, Brazil, 2000-2016.
The study identified several AMR genes in Salmonella enterica isolates from Brazil, including qnrE1, qnrB19, qnrS1, blaCTX-M-2, blaCTX-M-8, blaCMY-2, aadA1, aadA2, aac(3)-IVa, aac(3)-IIa, aac(6')-Ib, floR, sul1, sul2, tet(A), tet(B), strA, strB, drfA1, inu(F), qacEdelta1, and fosA7. These genes conferred resistance to various antibiotics such as fluoroquinolones, beta-lactams, aminoglycosides, sulfonamides, tetracyclines, chloramphenicol, trimethoprim, macrolides, quaternary ammonium compounds, and fosfomycin.
Comparative Genomics and Phenotypic Investigations Into Antibiotic, Heavy Metal, and Disinfectant Susceptibilities of Salmonella enterica Strains Isolated in Australia.
The study identified several AMR genes and mutations in Salmonella enterica strains, including blaTEM-1, aph(3')-I, aph(6')-ld, dfrA5, tetA, and various arsenic resistance genes. A mutation in gyrA was also found to confer nalidixic acid resistance.
Molecular Epidemiology of Multidrug-Resistant Klebsiella pneumoniae Isolates in a Brazilian Tertiary Hospital.
The study identified various AMR genes and mutations in multidrug-resistant Klebsiella pneumoniae isolates, including bla KPC, bla CTX-M, bla TEM, and mutations in ompk35, ompk36, gyrA, and parC. These findings highlight the complex resistance mechanisms contributing to the persistence of MDR-Kp in the hospital setting.
Genomic Sequence Analysis of the Multidrug-Resistance Region of Avian Salmonella enterica serovar Indiana Strain MHYL.
The study identified several AMR genes, including blaTEM, strA, tetA, floR, and aac(6')-Ib-cr, in the multidrug-resistant Salmonella enterica serovar Indiana strain MHYL. These genes were localized in two distinct MDR regions, RR1 and RR2, and were associated with resistance to multiple antibiotics.
Population dynamics of an Escherichia coli ST131 lineage during recurrent urinary tract infection.
The study identified multiple AMR genes and mutations in E. coli ST131 isolates from a patient with recurrent UTIs, including plasmid-borne resistance genes and chromosomal mutations contributing to fluoroquinolone resistance.
Multilocus sequence typing and bla (ESBL) characterization of extended-spectrum beta-lactamase-producing Escherichia coli isolated from healthy humans and swine in Northern Thailand.
The study identified bla CTX-M, bla TEM, and bla SHV as the primary ESBL genes in ESBL-producing E. coli isolates from healthy humans and swine in Northern Thailand. Additionally, several other AMR genes such as sul1, sul2, sul3, aadA22, aph(3')-Ia, strA, strB, aadA2, aadA5, qnrS1, tetA, tetB, tetD, arr2, and mefB were characterized.
Multilocus sequence typing and bla (ESBL) characterization of extended-spectrum beta-lactamase-producing Escherichia coli isolated from healthy humans and swine in Northern Thailand.
The study identified bla CTX-M, bla TEM, and bla SHV as the primary ESBL genes in ESBL-producing E. coli isolates from healthy humans and swine in Northern Thailand. Additionally, several other AMR genes such as sul1, sul2, sul3, aadA22, aph(3')-Ia, strA, strB, aadA2, aadA5, qnrS1, tetA, tetB, tetD, arr2, and mefB were characterized.
Tracking Carbapenem-Producing Klebsiella pneumoniae Outbreak in an Intensive Care Unit by Whole Genome Sequencing.
The study identified multiple carbapenem-resistant Klebsiella pneumoniae (CP-Kp) strains carrying various resistance genes, including blaKPC-2, blaNDM-1, and others, contributing to multidrug resistance. Plasmid analysis revealed the presence of resistance genes on different plasmids, highlighting the complexity of resistance mechanisms.
Whole-genome sequence analysis of multidrug-resistant uropathogenic strains of Escherichia coli from Mexico.
The study identified 29 antibiotic resistance genes in 24 multidrug-resistant uropathogenic E. coli strains from Mexico, including genes conferring resistance to aminoglycosides, fluoroquinolones, beta-lactams, chloramphenicol, sulfonamides, tetracycline, and trimethoprim. Notably, the genes strA, strB, blaTEM-1B, and sul2 were highly prevalent among the strains.
Evolution of Outbreak-Causing Carbapenem-Resistant Klebsiella pneumoniae ST258 at a Tertiary Care Hospital over 8 Years.
The study identifies various AMR genes in ST258 K. pneumoniae isolates, including blaKPC-2, blaKPC-3, aadA2, aadA1, blaTEM-1A, blaSHV-11, blaSHV-12, oqxA, oqxB, fosA, dfrA12, dfrA14, sul1, sul2, catA1, cml, and strAB, which confer resistance to multiple antibiotics.
Genetic characterization of a novel sequence type of multidrug-resistant Citrobacter freundii strain recovered from wastewater treatment plant.
The study reports the identification of a multidrug-resistant Citrobacter freundii strain R17 carrying 13 antibiotic-resistance genes, including blaCMY-85, aadA2, aac(3)-lld, blaDHA-1, blaTEM-1B, qnrB4, mph(A), catA2, sul1, sul2, tet(D), and dfrA12, which confer resistance to various antibiotic classes.
Inter-host Transmission of Carbapenemase-Producing Escherichia coli among Humans and Backyard Animals.
The study identified blaNDM genes as the primary cause of carbapenem resistance in Escherichia coli isolates from humans, pigs, chickens, and flies in rural China, highlighting the transmission of these resistance genes between humans and backyard animals.
Manure Application Did Not Enrich Antibiotic Resistance Genes in Root Endophytic Bacterial Microbiota of Cherry Radish Plants.
The study found that manure application increased the occurrence of antibiotic resistance genes (ARGs) in the rhizosphere and phyllosphere of cherry radish, but not in the endophytic bacterial microbiota of the root, which is the edible part of the plant.
Manure Application Did Not Enrich Antibiotic Resistance Genes in Root Endophytic Bacterial Microbiota of Cherry Radish Plants.
The study found that manure application increased the occurrence of antibiotic resistance genes (ARGs) in the rhizosphere and phyllosphere of cherry radish, but not in the endophytic bacterial microbiota of the root, which is the edible part of the plant.
Manure Application Did Not Enrich Antibiotic Resistance Genes in Root Endophytic Bacterial Microbiota of Cherry Radish Plants.
The study found that manure application increased the occurrence of antibiotic resistance genes (ARGs) in the rhizosphere and phyllosphere of cherry radish, but not in the endophytic bacterial microbiota of the root, which is the edible part of the plant.
Manure Application Did Not Enrich Antibiotic Resistance Genes in Root Endophytic Bacterial Microbiota of Cherry Radish Plants.
The study found that manure application increased the occurrence of antibiotic resistance genes (ARGs) in the rhizosphere and phyllosphere of cherry radish, but not in the endophytic bacterial microbiota of the root, which is the edible part of the plant.
The Resistome, Mobilome, Virulome and Phylogenomics of Multidrug-Resistant Escherichia coli Clinical Isolates from Pretoria, South Africa.
The study characterized the resistome, mobilome, and virulome of 20 multidrug-resistant E. coli isolates from Pretoria, South Africa. Key findings include the identification of various beta-lactamase genes (blaCTX-M-15, blaCTX-M-14, blaCTX-M-27, blaOXA-1, blaOXA-10, blaTEM-1B), aminoglycoside resistance genes (aac(3)-IIa, aac(3)-IId, aac(6')-Ib-cr, mph(A)), sulfonamide resistance genes (sul1, sul2, sul3), dihydrofolate reductase genes (dfrA17, dfrA14, dfrA1, dfrA5, dfrA7, dfrA12, dfrA23), tetracycline resistance genes (tet(A), tet(B)), chloramphenicol resistance genes (catB3, catA1), and fluoroquinolone resistance mutations in gyrA, gyrB, parC, and parE.
The Resistome, Mobilome, Virulome and Phylogenomics of Multidrug-Resistant Escherichia coli Clinical Isolates from Pretoria, South Africa.
The study characterized the resistome, mobilome, and virulome of 20 multidrug-resistant E. coli isolates from Pretoria, South Africa. Key findings include the identification of various beta-lactamase genes (blaCTX-M-15, blaCTX-M-14, blaCTX-M-27, blaOXA-1, blaOXA-10, blaTEM-1B), aminoglycoside resistance genes (aac(3)-IIa, aac(3)-IId, aac(6')-Ib-cr, mph(A)), sulfonamide resistance genes (sul1, sul2, sul3), dihydrofolate reductase genes (dfrA17, dfrA14, dfrA1, dfrA5, dfrA7, dfrA12, dfrA23), tetracycline resistance genes (tet(A), tet(B)), chloramphenicol resistance genes (catB3, catA1), and fluoroquinolone resistance mutations in gyrA, gyrB, parC, and parE.
Characteristics of a Colistin-Resistant Escherichia coli ST695 Harboring the Chromosomally-Encoded mcr-1 Gene.
The study identifies the chromosomally-encoded mcr-1 gene in a colistin-resistant E. coli ST695 strain, along with various other resistance genes such as bla NDM-1, aadA1, aadA2, aph(3')-Ia, aph(3')-VI, rmtB, cmlA1, floR, tet(A), tet(M), dfrA12, oqxA, oqxB, qnrS1, mph(A), bla TEM-105, and bla TEM-1B, contributing to its multidrug-resistant phenotype.
Complex Class 1 Integron in a Clinical Escherichia coli Strain From Vietnam Carrying Both mcr-1 and bla (NDM-1).
The study identifies a multidrug-resistant E. coli strain carrying both mcr-1 and bla NDM-1, highlighting the co-existence of colistin and carbapenem resistance genes in Vietnam.
Complex Class 1 Integron in a Clinical Escherichia coli Strain From Vietnam Carrying Both mcr-1 and bla (NDM-1).
The study identifies a multidrug-resistant E. coli strain carrying both mcr-1 and bla NDM-1, highlighting the co-existence of colistin and carbapenem resistance genes in Vietnam.
First Report of Coexistence of Three Different MDR Plasmids, and That of Occurrence of IMP-Encoding Plasmid in Leclercia adecarboxylata.
The study reports the first identification of three different multidrug-resistant (MDR) plasmids in a single clinical isolate of Leclercia adecarboxylata, including the blaIMP-8 gene encoded on an IMP-encoding plasmid. These plasmids harbor various AMR genes such as blaIMP-8, aacC2, aadA2, mph(A), sul1, qacED1, mer, chrA, dfrA12, tmrB, catA1, catB8, tet(C), blaCTX-M-9, and blaTEM-1.
Characterization of a Novel Conjugative Plasmid in Edwardsiella piscicida Strain MS-18-199.
The study characterizes a novel conjugative plasmid, pEPMS-18199, in Edwardsiella piscicida strain MS-18-199, which carries multiple antimicrobial resistance (AMR) genes including floR, tetA, tetR, sul2, strA, strB, arsA, and arsD, conferring resistance to phenicol, tetracycline, sulfonamide, and aminoglycoside antibiotics, as well as arsenic.
Multidrug-Resistant and Clinically Relevant Gram-Negative Bacteria Are Present in German Surface Waters.
The study identifies several AMR genes in multidrug-resistant Gram-negative bacteria isolated from German surface waters, highlighting the presence of clinically relevant resistance mechanisms such as bla CTX-M-1, bla CTX-M-15, mcr-1, and others.
Whole-Genome-Sequence-Based Characterization of Extensively Drug-Resistant Acinetobacter baumannii Hospital Outbreak.
The study identified two extensively drug-resistant Acinetobacter baumannii clones carrying blaOXA-23 and blaOXA-72, which confer resistance to carbapenems. Additional resistance genes such as aac(3')-Ia, ant(3'')-Ia, aph(3')-VIa, strA, strB, armA, blaADC-73, blaADC-74, blaTEM-1D, mph(E), and msr(E) were also detected.
Evaluating the genome and resistome of extensively drug-resistant Klebsiella pneumoniae using native DNA and RNA Nanopore sequencing.
The study identified multiple AMR genes in extensively drug-resistant Klebsiella pneumoniae isolates, including beta-lactamases (blaSHV-11, blaTEM-1B, blaVEB-1, blaOXA-10, blaKPC-2, blaOXA-9, blaVIM-27, blaCTX-M-15, blaOXA-1, blaOXA-48), aminoglycoside resistance genes (aadA1, ant(2'')-Ia, aph(6)-Id, arr-2, aadA24, aph(3')-Ia, aph(6)-Id, aac(3)-IIa, aac(6')Ib-cr, aac(6')-Ib, aac(6')-Ib-cr), sulfonamide resistance genes (sul1, sul2), tetracycline resistance genes (tet(A), tet(G)), trimethoprim resistance genes (dfrA1, dfrA14, dfrA23), chloramphenicol resistance genes (cmlA1, catB4), and others.
Genomic Characterization of New Variant of Hydrogen Sulfide (H(2)S)-Producing Escherichia coli with Multidrug Resistance Properties Carrying the mcr-1 Gene in China †
The study reports the first detection of a hydrogen sulfide (H2S)-producing Escherichia coli variant isolated from a human in China, with multidrug resistance properties, including colistin resistance mediated by the mcr-1 gene, along with other resistance genes such as aadA1, aadA2, dfrA12, blaTEM-1B, oqxA, oqxB, floR, cmlA1, sul3, and tet(A).
Genomic Investigation Reveals Contaminated Detergent as the Source of an Extended-Spectrum-β-Lactamase-Producing Klebsiella michiganensis Outbreak in a Neonatal Unit.
Genome-Based Analysis of Extended-Spectrum β-Lactamase-Producing Escherichia coli in the Aquatic Environment and Nile Perch (Lates niloticus) of Lake Victoria, Tanzania.
The study identified multiple AMR genes in ESBL-producing E. coli from Nile perch and water samples in Lake Victoria, including bla CTX-M-15, bla TEM-1B, aadA2, aac(3)-IId, sul1, sul2, dfrA12, qepA4, tetB, tetD, mphA, mdfA, catA1, strA, strB, nfaE, iss, vat, and lpfA.
Isolation of Drug-Resistant Gallibacterium anatis from Calves with Unresponsive Bronchopneumonia, Belgium.
The study identified 24 different antimicrobial-resistance determinants in Gallibacterium anatis isolates from calves with unresponsive bronchopneumonia, including novel resistance genes such as aadA23, blaCARB-8, tet(Y), and qnrD1.
Unusual accumulation of a wide array of antimicrobial resistance mechanisms in a patient with cytomegalovirus-associated hemophagocytic lymphohistiocytosis: a case report.
Characterization of an IMP-4-Producing Klebsiella pneumoniae ST1873 Strain Recovered from an Infant with a Bloodstream Infection in China.
The study characterizes an IMP-4-producing Klebsiella pneumoniae ST1873 strain, identifying multiple antimicrobial resistance genes including blaIMP-4, blaSHV-2, blaSHV-11, oqxA, oqxB, aph(6)-Id, strA, catA1, dfrA5, sul2, and fosA.
Metadata Analysis of mcr-1-Bearing Plasmids Inspired by the Sequencing Evidence for Horizontal Transfer of Antibiotic Resistance Genes Between Polluted River and Wild Birds.
The study identifies the mcr-1 gene as a key factor in colistin resistance in E. coli strains isolated from polluted rivers and wild birds. It also characterizes several other AMR genes including aadA1, aadA2, aph(3′)-Ia, aph(3″)-Ib, aph(4)-Ia, aph(6)-Id, tet(B), tet(D), tet(A), bla CTX–M–14, bla TEM–1, qnrS2, oqxA, oqxB, cmlA1, floR, vgaC, sul1, sul2, sul3, dfrA12, and glpT (E448K).
International clones of extended-spectrum β-lactamase (CTX-M)-producing Escherichia coli in peri-urban wild animals, Brazil.
The study identified various AMR genes in CTX-M-producing E. coli isolates from peri-urban wild animals in Brazil, including bla CTX-M-55, bla CTX-M-2, bla CTX-M-15, bla CTX-M-14, and others, indicating the presence of multidrug-resistant bacteria in wildlife.
Prevalence, Antimicrobial Resistance, Virulence Genes and Genetic Diversity of Salmonella Isolated from Retail Duck Meat in Southern China.
The study identified multiple antimicrobial resistance genes in Salmonella isolates from retail duck meat in Southern China, including blaTEM, blaCTX-M, strA, aadA1, qnrS, aac(6')-Ib, qnrB, and floR, which confer resistance to various antibiotics such as ampicillin, cefotaxime, streptomycin, ciprofloxacin, ofloxacin, and florfenicol.
Systematic Evaluation of Whole Genome Sequence-Based Predictions of Salmonella Serotype and Antimicrobial Resistance.
The study evaluated the performance of various bioinformatics tools for predicting antimicrobial resistance (AMR) and serotypes of Salmonella enterica using whole-genome sequencing (WGS). It identified several AMR genes and mutations associated with resistance to various antibiotics.
Antimicrobial resistance of Escherichia coli isolated from retail foods in northern Xinjiang, China.
The study identified various antimicrobial resistance genes in Escherichia coli isolates from retail foods in northern Xinjiang, China, including tetA, tetB, blaOXA, blaTEM, floR, sul1, sul2, aadAla, aadB, strA, and strB. These genes conferred resistance to tetracycline, beta-lactams, chloramphenicol, sulfonamides, and streptomycin.
Antimicrobial resistance of Escherichia coli isolated from retail foods in northern Xinjiang, China.
The study identified various antimicrobial resistance genes in Escherichia coli isolates from retail foods in northern Xinjiang, China, including tetA, tetB, blaOXA, blaTEM, floR, sul1, sul2, aadAla, aadB, strA, and strB. These genes conferred resistance to tetracycline, beta-lactams, chloramphenicol, sulfonamides, and streptomycin.
Novel Insights and Features of the NDM-5-Producing Escherichia coli Sequence Type 167 High-Risk Clone.
The study identifies the NDM-5-producing Escherichia coli sequence type 167 clone, highlighting its resistance mechanisms and the presence of various resistance genes such as blaNDM-5, aadA2, dfrA12, sul1, tet(A), mphA, rmtB, and aac(3)-IIa.
Genomic profiling of antimicrobial resistance genes in clinical isolates of Salmonella Typhi from patients infected with Typhoid fever in India.
The study identified several AMR genes and mutations in Salmonella Typhi isolates, including beta-lactamases (blaTEM-1B, blaTEM-116), chloramphenicol resistance gene (catA1), trimethoprim resistance genes (dfrA7, dfrA15), sulfamethoxazole resistance genes (sul1, sul2), and fluoroquinolone resistance mutations in gyrA, gyrB, parC, and parE genes.
Prevalence and distribution of antimicrobial resistance determinants of Escherichia coli isolates obtained from meat in South Africa.
The study identified several AMR genes in E. coli isolates from meat in South Africa, including aadA, strA, aph(3)-Ia, aph(3)-IIa, aac(3)-IIa, blaTEM, blaZ, ampC, cat1, cat2, cmlA1, sul1, sul2, tetA, tetB, tetC, tetD, and tetM, which confer resistance to various antibiotics such as streptomycin, kanamycin, neomycin, gentamicin, amoxicillin, ampicillin, chloramphenicol, cotrimoxazole, and tetracycline.
Mobile Genetic Elements Harboring Antibiotic Resistance Determinants in Acinetobacter baumannii Isolates From Bolivia.
The study identified multiple antibiotic resistance genes in Acinetobacter baumannii isolates from Bolivia, including bla OXA-23, strA, strB, aac(3)-IIa, aac(6')-Ian, sul2, tet(B), bla TEM-1B, and aadB, which contribute to resistance against carbapenems, aminoglycosides, sulfonamides, tetracycline, and beta-lactams.
Comparative analysis of multidrug resistance plasmids and genetic background of CTX-M-producing Escherichia coli recovered from captive wild animals.
The study identifies multiple AMR genes and mutations in MDR E. coli strains from captive wild animals, highlighting the presence of CTX-M-8 and CTX-M-65 beta-lactamases, along with various other resistance mechanisms such as aminoglycoside, tetracycline, and fluoroquinolone resistance genes, as well as mutations in quinolone resistance-determining regions.
Rapid detection of antibiotic resistance genes in lactic acid bacteria using PMMA-based microreactor arrays.
The study presents a PMMA-based microreactor array for rapid detection of antibiotic resistance (AR) genes in lactic acid bacteria (LABs). Six AR genes, including strA, strB, vanA, vanB, tetM, and tetS, were successfully detected using LAMP and colorimetric methods.
Whole Genome Sequencing Analysis of Porcine Faecal Commensal Escherichia coli Carrying Class 1 Integrons from Sows and Their Offspring.
The study identified multiple antimicrobial resistance genes in porcine faecal commensal E. coli, including blaTEM-1, strA, strB, tetA, dfrA12, aadA1, aadA2, cmlA, aph(3')-Ia, sul2, and sul3, which confer resistance to beta-lactams, streptomycin, tetracyclines, trimethoprim, aminoglycosides, chloramphenicol, neomycin, kanamycin, and sulfonamides.
Whole Genome Sequencing Analysis of Porcine Faecal Commensal Escherichia coli Carrying Class 1 Integrons from Sows and Their Offspring.
The study identified multiple antimicrobial resistance genes in porcine faecal commensal E. coli, including blaTEM-1, strA, strB, tetA, dfrA12, aadA1, aadA2, cmlA, aph(3')-Ia, sul2, and sul3, which confer resistance to beta-lactams, streptomycin, tetracyclines, trimethoprim, aminoglycosides, chloramphenicol, neomycin, kanamycin, and sulfonamides.
Plasmid Replicon Typing of Antibiotic-Resistant Escherichia coli From Clams and Marine Sediments.
The study identified various antibiotic resistance genes in E. coli isolates from clams and marine sediments, including blaTEM, blaSHV, blaCTX-M, tet(A), dfrA1, aadA, strA, strB, and ant(3"). These genes were associated with resistance to beta-lactams, tetracycline, trimethoprim/sulfamethoxazole, and streptomycin.
Genomic Characterisation of a Multiple Drug Resistant IncHI2 ST4 Plasmid in Escherichia coli ST744 in Australia.
The study describes the first complete sequence of a multiple drug-resistant IncHI2 ST4 plasmid, pTZ41_1P, from a commensal E. coli in Australia. The plasmid carries genes conferring resistance to heavy metals, beta-lactams, aminoglycosides, and sulfonamides.
Structural Genomics of repA, repB 1-Carrying IncFIB Family pA1705-qnrS, P911021-tetA, and P1642-tetA, Multidrug-Resistant Plasmids from Klebsiella pneumoniae.
The study characterizes multidrug-resistant plasmids pA1705-qnrS, p911021-tetA, and p1642-tetA from Klebsiella pneumoniae, identifying several AMR genes including beta-lactamases (bla CTX-M-14, bla TEM-1, bla OXA-1, bla SHV-12, bla CTX-M-15, bla CTX-M-65), quinolone resistance gene qnrS1, tetracycline resistance genes tetA (A) and tetA (D), aminoglycoside resistance genes aacA4cr and aacC2, streptomycin resistance genes strA and strB, dihydrofolate reductase genes dfrA1 and dfrA14, sulfonamide resistance gene sul2, macrolide resistance gene mph (A), efflux pump gene oqxAB, chloramphenicol acetyltransferase gene catB3, and tunicamycin resistance gene tmrB.
High-resolution characterisation of ESBL/pAmpC-producing Escherichia coli isolated from the broiler production pyramid.
The study identified multiple AMR genes, including bla CTX-M-55, bla CMY-2, bla CTX-M-1, bla SHV-12, sul2, aac(3)-Ia, aadA, strA, strB, tet(A), tet(B), dfrA14, floR, cmlA1, catA1, catB3, qnrS1, qnrS2, qnrB19, mph(A), mph(B), arr-3, and aac(6')Ib-cr, in ESBL/pAmpC-producing E. coli isolates from broiler production.
Comparative Genomics of Acinetobacter baumannii Clinical Strains From Brazil Reveals Polyclonal Dissemination and Selective Exchange of Mobile Genetic Elements Associated With Resistance Genes.
The study identifies multiple beta-lactamase genes, including blaTEM-1, blaADC-182, and blaOXA-253, as well as aminoglycoside resistance genes such as aph3 and aadB, which contribute to the multidrug resistance profile of Acinetobacter baumannii clinical strains in Brazil.
AbGRI4, a novel antibiotic resistance island in multiply antibiotic-resistant Acinetobacter baumannii clinical isolates.
The study identifies a novel antibiotic resistance island, AbGRI4, in multiply antibiotic-resistant Acinetobacter baumannii clinical isolates. AbGRI4 contains a class 1 integron with aadB, aadA2, and sul1 genes, conferring resistance to aminoglycosides and sulfonamides.
Emerging Antimicrobial-Resistant High-Risk Klebsiella pneumoniae Clones ST307 and ST147.
The study identifies and characterizes the antimicrobial resistance genes and mutations associated with the high-risk Klebsiella pneumoniae clones ST307 and ST147, highlighting their global spread and the diversity of resistance mechanisms they employ.
Mechanisms Protecting Acinetobacter baumannii against Multiple Stresses Triggered by the Host Immune Response, Antibiotics and Outside-Host Environment.
This review discusses the mechanisms that protect Acinetobacter baumannii against multiple stresses, including those from the host immune response, antibiotics, and the outside environment. It highlights the role of surface glycoconjugates, outer membrane components, and various virulence factors in evading immune defenses and surviving adverse conditions.
Occurrence and Antimicrobial Resistance Traits of Escherichia coli from Wild Birds and Rodents in Singapore.
F Plasmids Are the Major Carriers of Antibiotic Resistance Genes in Human-Associated Commensal Escherichia coli.
The study identifies various antibiotic resistance genes in commensal E. coli isolates, highlighting the prevalence of resistance genes on F plasmids and the role of mobile genetic elements in their dissemination.
Scarless Removal of Large Resistance Island AbaR Results in Antibiotic Susceptibility and Increased Natural Transformability in Acinetobacter baumannii.
The study shows that removing the AbaR resistance island from Acinetobacter baumannii restores antibiotic susceptibility and increases natural transformability. Several AMR genes within AbaR were identified, including aadB, aacC1, aphA1b, aacA, aadA1, strA, strB, blaVEB-1, blaOXA-10, sul1, dhfrI, dhfrX, tetA(A), tetA(G), cmlA1, cmlA5, cmlA9, catA1, arr-2, and sup.
Antibiotic Susceptibility Testing (AST) Reports: A Basis for Environmental/Epidemiological Surveillance and Infection Control Amongst Environmental Vibrio cholerae.
The study identified various antibiotic resistance genes in Vibrio cholerae isolates, including blaTEM, NDM-1, AmpC, and ESBL, indicating multidrug resistance in environmental V. cholerae.
Tracking Antimicrobial Resistance Determinants in Diarrheal Pathogens: A Cross-Institutional Pilot Study.
The study identified 55 different antimicrobial resistance determinants in diarrheal pathogens, highlighting the presence of genes conferring resistance to multiple antibiotic classes, including beta-lactams, aminoglycosides, macrolides, tetracyclines, phenicols, sulfonamides, and others. Notably, carbapenemase genes like bla OXA-48 and bla NDM were detected in certain isolates, indicating emerging resistance concerns.
Tracking Antimicrobial Resistance Determinants in Diarrheal Pathogens: A Cross-Institutional Pilot Study.
The study identified 55 different antimicrobial resistance determinants in diarrheal pathogens, highlighting the presence of genes conferring resistance to multiple antibiotic classes, including beta-lactams, aminoglycosides, macrolides, tetracyclines, phenicols, sulfonamides, and others. Notably, carbapenemase genes like bla OXA-48 and bla NDM were detected in certain isolates, indicating emerging resistance concerns.
Comparative Genomic Analysis of 450 Strains of Salmonella enterica Isolated from Diseased Animals.
The study identified 60 antimicrobial resistance genes (ARGs), 4 disinfectant resistance genes (DRGs), and 33 heavy metal resistance genes (HMRGs) in 450 Salmonella strains isolated from diseased animals. These genes contributed to resistance against multiple antimicrobial classes, including aminoglycosides, beta-lactams, tetracyclines, sulfonamides, and phenicols.
Molecular Characterization of a Novel Integrative Conjugative Element ICEHpa1 in Haemophilus parasuis.
The study identifies a novel integrative conjugative element, ICE Hpa1, carrying seven distinct resistance genes in Haemophilus parasuis, highlighting its role in multidrug resistance.
Molecular Characteristics and Zoonotic Potential of Salmonella Weltevreden From Cultured Shrimp and Tilapia in Vietnam and China.
The study identified aminoglycoside resistance gene aac(6')-Iaa, streptomycin resistance genes strA and strB, sulfonamide resistance gene sul2, tetracycline resistance gene tet(A), and a quinolone resistance mutation in parC (p.T57S) in Salmonella Weltevreden isolates from shrimp and tilapia in Vietnam and China.
Antimicrobial Resistance in Escherichia coli and Resistance Genes in Coliphages from a Small Animal Clinic and in a Patient Dog with Chronic Urinary Tract Infection.
The study identified several antimicrobial resistance genes in E. coli isolates from a dog with chronic urinary tract infection, including blaTEM, dfr, sulI, sulII, and strA. These genes conferred resistance to ampicillin, trimethoprim, and sulfonamides, as well as streptomycin. Additionally, some coliphages were found to carry these resistance genes.
Genome Characterization of mcr-1-Positive Escherichia coli Isolated From Pigs With Postweaning Diarrhea in China.
The study identifies multiple antimicrobial resistance genes, including mcr-1.1 and mcr-3.1, in multidrug-resistant E. coli isolates from pigs with postweaning diarrhea in China.
Genome Characterization of mcr-1-Positive Escherichia coli Isolated From Pigs With Postweaning Diarrhea in China.
The study identifies multiple antimicrobial resistance genes, including mcr-1.1 and mcr-3.1, in multidrug-resistant E. coli isolates from pigs with postweaning diarrhea in China.
Characterization of Multidrug Resistance Patterns of Emerging Salmonella enterica Serovar Rissen along the Food Chain in China.
The study identified multiple AMR genes in Salmonella enterica serovar Rissen isolates, including tet(A), blaTEM-1B, aadA2, aadA1, aac(6')-Iaa, aph(3")-lld, sul3, and dfrA12, which confer resistance to various antibiotics such as tetracycline, ampicillin, streptomycin, sulfisoxazole, and trimethoprim-sulfamethoxazole.
The Role of Urban Wastewater in the Environmental Transmission of Antimicrobial Resistance: The Current Situation in Italy (2010-2019).
The study identified several AMR genes in urban wastewater treatment plants in Italy, including bla TEM-1, bla AmpC, bla CTX-M-15, bla KPC-3, bla SHV-1, tet A, sul II, erm B, qnr S, int I1, aad A2, dfr 17, aadA 5, aadA 10, sat 1, bla TEM, bla OXA, bla CTX, bla KPC, and tet W. These genes confer resistance to various antibiotics such as beta-lactams, tetracyclines, sulfonamides, macrolides, fluoroquinolones, and aminoglycosides.
American Crows as Carriers of Extra Intestinal Pathogenic E. coli and Avian Pathogenic-Like E. coli and Their Potential Impact on a Constructed Wetland.
The study identifies several AMR genes, including blaCMY-2, blaCTX-M, tet(A), tet(B), strA, and strB, in E. coli isolates from crows and wetland water, highlighting the potential for these genes to be transferred via plasmids and contributing to the spread of antibiotic resistance.
Occurrence of Antibiotic-Resistant Bacteria and Genes in Two Drinking Water Treatment and Distribution Systems in the North-West Province of South Africa.
The study identified several antibiotic resistance genes, including strA, strB, aadA, dfrB, bla CTX-M, and tetA, in heterotrophic bacteria from drinking water treatment and distribution systems in South Africa.
Prevalence and antibiotic susceptibility of Mannheimia haemolytica and Pasteurella multocida isolated from ovine respiratory infection: A study from Karnataka, Southern India.
The study identified antibiotic resistance genes such as strA (32.7%) and sul2 (32.7%) associated with streptomycin and sulfonamide resistance, respectively, in M. haemolytica and P. multocida isolates.
Snapshot Study of Whole Genome Sequences of Escherichia coli from Healthy Companion Animals, Livestock, Wildlife, Humans and Food in Italy.
The study identified multiple antimicrobial resistance genes (ARGs) and mutations in Escherichia coli isolates from various sources in Italy, highlighting the prevalence of resistance to tetracycline, sulfonamide, penicillin, fluoroquinolone, and colistin. Key genes included tetA, sul2, blaTEM-1b, mcr-1, qnrS1, and others, along with mutations in gyrA, parC, parE, and pmrB.
Snapshot Study of Whole Genome Sequences of Escherichia coli from Healthy Companion Animals, Livestock, Wildlife, Humans and Food in Italy.
The study identified multiple antimicrobial resistance genes (ARGs) and mutations in Escherichia coli isolates from various sources in Italy, highlighting the prevalence of resistance to tetracycline, sulfonamide, penicillin, fluoroquinolone, and colistin. Key genes included tetA, sul2, blaTEM-1b, mcr-1, qnrS1, and others, along with mutations in gyrA, parC, parE, and pmrB.
Pyomelanin biosynthetic pathway in pigment-producer strains from the pandemic Acinetobacter baumannii IC-5.
The study characterizes the pyomelanin biosynthetic pathway in XDR Acinetobacter baumannii strains, identifying several AMR genes including aac(6')-Ian, aac(3')-IIe, strA, strB, cmlA, sul1, bla TEM-1b, bla ADC-5, bla OXA-65, and bla OXA-23, which contribute to extensive drug resistance.
The importance of using whole genome sequencing and extended spectrum beta-lactamase selective media when monitoring antimicrobial resistance.
The study highlights the utility of whole genome sequencing (WGS) in monitoring antimicrobial resistance (AMR) trends, particularly in identifying ESBL genes such as bla CTX-M-1, bla CTX-M-15, bla SHV-12, bla CMY-2, and bla DHA-1, along with other resistance genes like sul2, tet(A), dfrA17, aadA5, ant3-1a, strA, strB, and fosA3 in E. coli isolates from pig surveillance.
Whole-Genome Sequence Analysis of an Extensively Drug-Resistant Salmonella enterica Serovar Agona Isolate from an Australian Silver Gull (Chroicocephalus novaehollandiae) Reveals the Acquisition of Multidrug Resistance Plasmids.
The study identifies multiple antimicrobial resistance genes in a multidrug-resistant Salmonella enterica serovar Agona isolate from a silver gull, including bla CTX-M-55, dfrA14, sul3, qnrS1, tet(A), bla TEM-1, and others, indicating the acquisition of multidrug resistance plasmids.
Antimicrobial Resistance and Genomic Characterization of OXA-48- and CTX-M-15-Co-Producing Hypervirulent Klebsiella pneumoniae ST23 Recovered from Nosocomial Outbreak.
The study characterizes the AMR genes in a multidrug-resistant hypervirulent Klebsiella pneumoniae ST23 isolate, MAR14-456, which co-produces OXA-48 and CTX-M-15. The isolate shows resistance to multiple antibiotics, including carbapenems, cephalosporins, and aminoglycosides.
Genomic epidemiology of Escherichia coli isolates from a tertiary referral center in Lilongwe, Malawi.
The study identifies the blaCTX-M-15 gene as a major contributor to cephalosporin resistance in Escherichia coli isolates from Malawi, along with other AMR genes such as aac(3)-IIa, aac(3)-IId, aadA5, ant(3'')-Ih, aph(3'')-Ib, aph(3')-Ia, aph(6)-Id, strA, strB, acrF, emrD, mdtM, blaTEM-1, catA1, catB3, dfrA17, sul2, mph(A), and tet(A).
Genome-based characterization of Escherichia coli causing bloodstream infection through next-generation sequencing.
The study identified various AMR genes in E. coli isolates from bloodstream infections, including genes conferring resistance to beta-lactams, macrolides, aminoglycosides, chloramphenicol, and trimethoprim. Additionally, mutations in quinolone resistance-determining regions of gyrA, parC, and parE were associated with ciprofloxacin resistance.
A Longitudinal Evaluation of the Bacterial Pathogens Colonizing Chronic Non-Healing Wound Sites at a United States Military Treatment Facility in the Pacific Region.
The study identified multiple antimicrobial resistance genes in bacterial isolates from chronic non-healing wounds, including beta-lactamases, aminoglycoside modifying enzymes, macrolide resistance genes, and others. These genes were found in various bacterial species such as E. coli, S. aureus, P. aeruginosa, and others.
Characterization of Enterococci- and ESBL-Producing Escherichia coli Isolated from Milk of Bovides with Mastitis in Egypt.
The study identified several AMR genes in Enterococcus and ESBL-producing E. coli isolates from bovine mastitis cases in Egypt, including erm(B), tetL, aac-aphD, vanA, and vanB.
Distribution of Beta-Lactamase Producing Gram-Negative Bacterial Isolates in Isabela River of Santo Domingo, Dominican Republic.
The study identified several beta-lactamase genes, including bla TEM, bla OXA, bla SHV, and bla KPC, as well as other resistance genes such as CTX-M-15, CTX-M-55, OXA-1, OXA-72, OXA-132, KPC-3, QnrS1, QnrB19, sul2, sul1, dfrA12, dfrA14, dfrA17, mphA, aadA, aadA2, aadA5, ampC, ampC1, ampH, PmrF, bacA, and eptA, in various Gram-negative bacterial isolates from the Isabela River in the Dominican Republic.
Comparative genomic and phenotypic characterization of invasive non-typhoidal Salmonella isolates from Siaya, Kenya.
The study identified several AMR genes in Salmonella isolates from Kenya, including blaTEM-1, aadA1, strA, strB, catA1, dhfr1, sul1, and sul2, which confer resistance to various antibiotics such as penicillins, cephalosporins, streptomycin, chloramphenicol, trimethoprim, and sulfonamides.
Endophytic Lifestyle of Global Clones of Extended-Spectrum β-Lactamase-Producing Priority Pathogens in Fresh Vegetables: a Trojan Horse Strategy Favoring Human Colonization?
The study identifies multiple AMR genes in endophytic ESBL-producing Enterobacterales isolated from fresh vegetables, highlighting their potential role in the spread of antibiotic resistance.
Genome-wide genetic marker analysis and genotyping of Escherichia fergusonii strain OTSVEF-60.
The study identified multiple antimicrobial resistance genes in Escherichia fergusonii strain OTSVEF-60, including aadA2, blaTEM-1, dfrA12, qnrS1, sul1, sul2, and tet(A), which confer resistance to aminoglycosides, beta-lactams, diaminopyrimidines, fluoroquinolones, sulfonamides, and tetracyclines.
Plasmid-Borne and Chromosomal ESBL/AmpC Genes in Escherichia coli and Klebsiella pneumoniae in Global Food Products.
The study identified several beta-lactamase genes, including bla CTX-M-1, bla CTX-M-15, bla CTX-M-55, bla CTX-M-65, bla SHV-12, bla SHV-28, bla SHV-81, bla TEM-1B, bla TEM-52C, bla CARB-2, bla OXA-1, bla DHA-1, and bla CMY-2, along with other AMR genes such as aac(3)-IIa, aac(6')-Ib-cr, aph(3')-Ia, aph(3')-Ib, aph(6)-Id, aadA1, aadA2, aph(4)-Ia, oqxA, oqxB, qnrB1, qnrS1, floR, sul2, sul1, tet(A), dfrA14, dfrA1, dfrA17, dfrA8, dfrA12, dfrA16, dfrA15, catB3, cmlA1, arr-2, and qnrB19, which confer resistance to various antibiotics in Escherichia coli and Klebsiella pneumoniae isolated from food products.
Utility of whole-genome sequencing during an investigation of multiple foodborne outbreaks of Shigella sonnei.
The study identified multiple antimicrobial resistance genes in the Shigella sonnei outbreak strain, including blaCTX-M-15, qnrS1, strA, strB, dfrA1, tetA, and sul2, which conferred resistance to various antibiotics such as ceftazidime, ciprofloxacin, streptomycin, trimethoprim, tetracycline, and sulfamethoxazole.
Institutional outbreak involving multiple clades of IMP-producing Enterobacter cloacae complex sequence type 78 at a cancer center in Tokyo, Japan.
The study identified multiple clades of IMP-producing Enterobacter cloacae complex sequence type 78 (ST78) strains causing an institutional outbreak. These strains carried blaIMP-1 and blaIMP-11 genes on IncHI2 and IncL/M plasmids, along with various other resistance genes such as aac(6')-IIc, qnrB6, fosA, sul1, and tet(B).
Analysis of antibiotic resistance phenotypes and genes of Escherichia coli from healthy swine in Guizhou, China.
The study identified multiple antibiotic resistance genes in Escherichia coli isolates from healthy swine in Guizhou, China, highlighting the prevalence of multidrug resistance, particularly for tetracycline, doxycycline, and sulfisoxazole. Key genes included blaTEM, blaCTX-M-9G, aac(3')-IV, aadA1, aadA2, floR, qnrS, oqxA, and mcr-1.
Genetic Characterization of AmpC and Extended-Spectrum Beta-Lactamase Phenotypes in Escherichia coli and Salmonella From Alberta Broiler Chickens.
The study identified bla CMY-2 and bla TEM genes in E. coli and Salmonella isolates from Alberta broiler chickens, contributing to beta-lactam resistance. Additionally, aadA, aadA1a, and aadA2 genes were found to confer resistance to streptomycin.
Clonal Clusters, Molecular Resistance Mechanisms and Virulence Factors of Gram-Negative Bacteria Isolated from Chronic Wounds in Ghana.
The study identified various AMR genes and mutations in Gram-negative bacteria isolated from chronic wounds in Ghana, including beta-lactamases, fosfomycin resistance genes, chloramphenicol resistance genes, aminoglycoside resistance genes, fluoroquinolone resistance genes, tetracycline resistance genes, sulfonamide resistance genes, trimethoprim resistance genes, and efflux pumps. Mutations in gyrA, parE, and parC were also found to contribute to fluoroquinolone resistance.
Antimicrobial Resistance Profile and ExPEC Virulence Potential in Commensal Escherichia coli of Multiple Sources.
The study identified several AMR genes, including blaCTX-M, mcr-1, and qnrS1, which confer resistance to cephalosporins, colistin, and fluoroquinolones, respectively, in commensal E. coli from various sources.
Emergence of High Level Carbapenem and Extensively Drug Resistant Escherichia coli ST746 Producing NDM-5 in Influent of Wastewater Treatment Plant, Seoul, South Korea.
The study reports the emergence of a high-level carbapenem-resistant and extensively drug-resistant (XDR) Escherichia coli strain N7 producing NDM-5, highlighting the presence of multiple resistance genes on plasmids and chromosomes.
Genomic Diversity and Virulence Potential of ESBL- and AmpC-β-Lactamase-Producing Escherichia coli Strains From Healthy Food Animals Across Europe.
The study identifies various ESBL and AmpC beta-lactamase genes, including bla SHV-12, bla CTX-M-1, bla CTX-M-2, bla CTX-M-14, bla CTX-M-15, bla TEM-52, and bla CMY-2, along with the mcr-1 gene conferring colistin resistance in E. coli isolates from food animals in Europe.
High-Level Aminoglycoside Resistance in Human Clinical Klebsiella pneumoniae Complex Isolates and Characteristics of armA-Carrying IncHI5 Plasmids.
The study identified armA and multiple aminoglycoside resistance genes (AMEs) on a conjugative IncHI5 plasmid in a high-level aminoglycoside-resistant Klebsiella variicola isolate. The plasmid p2757-346 carried two copies of armA along with six AME genes, highlighting the potential for dissemination of these resistance determinants.
Antimicrobial Resistance Genes in ESBL-Producing Escherichia coli Isolates from Animals in Greece.
The study identified several AMR genes in ESBL-producing E. coli isolates from animals in Greece, including bla CTX-M-1/15, bla TEM, aadA1, aadA2, aphA, strA, strB, sul1, sul2, sul3, dfrA1, dfrA5, dfrA7, dfrA12, dfrA14, dfrA15, dfrA17, dfrA19, mph, mrx, intI1, tnpISE cp1, qnrS, and qnrB.
Antimicrobial Resistance Genes in ESBL-Producing Escherichia coli Isolates from Animals in Greece.
The study identified several AMR genes in ESBL-producing E. coli isolates from animals in Greece, including bla CTX-M-1/15, bla TEM, aadA1, aadA2, aphA, strA, strB, sul1, sul2, sul3, dfrA1, dfrA5, dfrA7, dfrA12, dfrA14, dfrA15, dfrA17, dfrA19, mph, mrx, intI1, tnpISE cp1, qnrS, and qnrB.
Virulence and Antimicrobial Resistance Profiles of Salmonella enterica Serovars Isolated from Chicken at Wet Markets in Dhaka, Bangladesh.
The study identified multiple antimicrobial resistance genes, including blaTEM, tetA, sul1, and strA/B, in Salmonella enterica serovars isolated from chicken at wet markets in Dhaka, Bangladesh. These genes conferred resistance to various antibiotics such as ampicillin, tetracycline, sulfamethoxazole-trimethoprim, and streptomycin.
pCTX-M3-Structure, Function, and Evolution of a Multi-Resistance Conjugative Plasmid of a Broad Recipient Range.
The study characterizes the pCTX-M3 plasmid, highlighting its role in the dissemination of antibiotic resistance genes, including bla CTX-M-3, armA, aadA2, dfrA12, sul1, and bla TEM-1. These genes confer resistance to various antibiotics such as beta-lactams, aminoglycosides, sulfonamides, and trimethoprim.
On-Farm Anaerobic Digestion of Dairy Manure Reduces the Abundance of Antibiotic Resistance-Associated Gene Targets and the Potential for Plasmid Transfer.
The study found that anaerobic digestion of dairy manure significantly reduced the abundance of antibiotic resistance genes, including various ESBL genes such as bla CTX-M-1, bla CTX-M-14, bla CTX-M-15, bla CTX-M-27, bla CTX-M-55, and bla PER-1, as well as other resistance genes like aac(6')-Ib-cr, aph(3')-Ib, aph(6)-Id, bla OXA-1, catB4, dfrA1, floR, lnu(G), sul2, aadA2, mph(E), msr(E), tet(C), tet(E), and tet(X).
Genomic Insights into Drug Resistance and Virulence Platforms, CRISPR-Cas Systems and Phylogeny of Commensal E. coli from Wildlife.
The study identified various AMR genes in commensal E. coli strains from wildlife, including bla TEM-1, bla CTX-M-1, tet(A), tet(B), and several resistance gene cassettes in integrons. These genes were found to confer resistance to multiple antibiotics, highlighting the presence of AMR in wildlife E. coli populations.
Genomic Insights into Drug Resistance and Virulence Platforms, CRISPR-Cas Systems and Phylogeny of Commensal E. coli from Wildlife.
The study identified various AMR genes in commensal E. coli strains from wildlife, including bla TEM-1, bla CTX-M-1, tet(A), tet(B), and several resistance gene cassettes in integrons. These genes were found to confer resistance to multiple antibiotics, highlighting the presence of AMR in wildlife E. coli populations.
Diversity of Plasmids and Genes Encoding Resistance to Extended-Spectrum β-Lactamase in Escherichia coli from Different Animal Sources.
The study identified various AMR genes and mutations in E. coli isolates from different animal sources, highlighting the presence of ESBL genes such as bla CTX-M-15, bla TEM-1B, and bla CMY-28, as well as mutations in parC and gyrA that confer resistance to fluoroquinolones.
Diversity of Plasmids and Genes Encoding Resistance to Extended-Spectrum β-Lactamase in Escherichia coli from Different Animal Sources.
The study identified various AMR genes and mutations in E. coli isolates from different animal sources, highlighting the presence of ESBL genes such as bla CTX-M-15, bla TEM-1B, and bla CMY-28, as well as mutations in parC and gyrA that confer resistance to fluoroquinolones.
Presence of β-Lactamase-producing Enterobacterales and Salmonella Isolates in Marine Mammals.
The study identified various β-lactamase genes, including bla CMY-2, bla TEM-1, bla SHV-33, bla SHV-11, bla CTX-M-15, bla OXA-1, and bla DHA-1, along with non-β-lactamase resistance genes such as sul2, strA, strB, tet(A), and sul1, in Enterobacterales and Salmonella isolates from marine mammals.
Genomic analysis and phylogenetic position of the complex IncC plasmid found in the Spanish monophasic clone of Salmonella enterica serovar Typhimurium.
The study identifies various AMR genes in the IncC plasmid pUO-STmRV1, including blaTEM-1, cmlA1, aac(3)-IV, aadA1, aadA2, sul1, sul2, sul3, tet(A), dfrA12, arsR2, arsH, merRTPCADE, and silESRCBAP, which confer resistance to antibiotics and heavy metals.
Clinical evolution of ST11 carbapenem resistant and hypervirulent Klebsiella pneumoniae.
The study identifies a conjugative plasmid p17ZR-91-Vir-KPC that encodes both carbapenem resistance and hypervirulence in Klebsiella pneumoniae, providing insight into the evolution of ST11 carbapenem-resistant and hypervirulent strains.
The Spatiotemporal Dynamics and Microevolution Events That Favored the Success of the Highly Clonal Multidrug-Resistant Monophasic Salmonella Typhimurium Circulating in Europe.
The study identifies various AMR genes in the highly clonal multidrug-resistant monophasic Salmonella Typhimurium ST34, including beta-lactamases, sulfonamide resistance genes, tetracycline resistance genes, phenicol resistance genes, and polymyxin resistance genes.
Subtypes, resistance and virulence platforms in extended-drug resistant Acinetobacter baumannii Romanian isolates.
The study identifies several AMR genes including bla OXA-23, bla OXA-24, bla OXA-51, and various aminoglycoside, sulfonamide, tetracycline, and macrolide resistance genes in XDR A. baumannii isolates from Romania.
Molecular Analysis of Antimicrobial Resistance among Enterobacteriaceae Isolated from Diarrhoeic Calves in Egypt.
The study identified multiple antimicrobial resistance genes, including blaTEM, floR, dfrA1, dfrA17, aadA1, aadA2, aadA5, catB3, sat1, and blaPse1, in Enterobacteriaceae isolates from diarrhoeic calves in Egypt. These genes confer resistance to various antibiotics such as ampicillin, tetracycline, chloramphenicol, and others.
Genomic Analysis of Delftia tsuruhatensis Strain TR1180 Isolated From A Patient From China With In4-Like Integron-Associated Antimicrobial Resistance.
The study identified multiple antimicrobial resistance genes in Delftia tsuruhatensis TR1180, including blaOXA-118, oqxB, dfrA16, aac(6')-Ib3, aadA2, sul1, floR, and tet(G), which correspond to the strain's resistance to beta-lactams, fluoroquinolones, sulfonamides, aminoglycosides, and tetracyclines.
Foodborne Pathogenic Vibrios: Antimicrobial Resistance.
The paper discusses the presence of various antibiotic resistance genes in Vibrio species, including strB, sul2, tetA, blaTEM, qnrA, ermB, floR, aac(3)-IIa, blaNDM-1, blaCMY, blaP1, catB3, and others, which confer resistance to antibiotics such as streptomycin, sulfamethoxazole, tetracycline, ampicillin, fluoroquinolones, erythromycin, florfenicol, gentamicin, carbapenems, chloramphenicol, and trimethoprim.
Genomic Epidemiology of Multidrug-Resistant Nontyphoidal Salmonella in Young Children Hospitalized for Gastroenteritis.
Genomic insights into the diversity, virulence and resistance of Klebsiella pneumoniae extensively drug resistant clinical isolates.
The study identified various beta-lactamase genes, including blaSHV-11, blaKPC-2, and blaNDM-1, along with qnrS1, aadA1, dfrA1, and sul1, which contribute to multidrug resistance in extensively drug-resistant Klebsiella pneumoniae isolates.
Antimicrobial Resistance of Non-Typhoid Salmonella in Meat and Meat Products.
The study highlights the prevalence of antimicrobial resistance in non-typhoid Salmonella isolates from meat and meat products, emphasizing the resistance patterns to antibiotics such as tetracycline, sulfonamides, ampicillin, and streptomycin. It identifies Enteritidis and Typhimurium as the most common serovars with significant resistance levels.
Metagenomic analysis of MWWTP effluent treated via solar photo-Fenton at neutral pH: Effects upon microbial community, priority pathogens, and antibiotic resistance genes.
Solar photo-Fenton treatment effectively removed a wide range of antibiotic resistance genes (ARGs) including those conferring resistance to sulfonamides, macrolides, tetracyclines, and beta-lactams. The study identified several ARGs such as sul1, sul2, tet(X), erm(F), mph(A), mph(E), msr(E), aadA, aph(3"), aph(6), strA, and blaBKC.
Virulence and Antibiotic Resistance Characteristics of Vibrio Isolates From Rustic Environmental Freshwaters.
The study identified several antibiotic resistance genes in Vibrio isolates from environmental freshwater sources, including aadA, strA, aphA1, catII, ampC, blaTEM, blaGES, blaOXA-48, blaIMP, blaVIM, blaKPC, and qnrVC, indicating a significant risk of antimicrobial resistance in these bacteria.
Discerning the Antimicrobial Resistance, Virulence, and Phylogenetic Relatedness of Salmonella Isolates Across the Human, Poultry, and Food Materials Sources in Malaysia.
The study identified several AMR genes in Salmonella Enteritidis isolates from Malaysia, including aac(6')-ly, blaCMY-2, blaTEM-1, blaTEM-33, blaTEM-4, dfrA14, dfrA15, floR, qnrS1, qnrD1, sul1, sul2, strA, strB, tetA, and tetC. These genes conferred resistance to various antibiotics such as gentamicin, ampicillin, chloramphenicol, ciprofloxacin, sulfamethazine/trimethoprim, and tetracycline.
Infective endocarditis caused by Enterobacteriaceae: phenotypic and molecular characterization of Escherichia coli and Klebsiella pneumoniae in Rio de Janeiro, Brazil.
The study identified several AMR genes in E. coli and K. pneumoniae isolates causing infective endocarditis, including genes conferring resistance to beta-lactams, aminoglycosides, sulfonamides, trimethoprim, fosfomycin, and fluoroquinolones. These genes were detected through molecular analysis and resistance profiling.
Occurrence of Colibacillosis in Broilers and Its Relationship With Avian Pathogenic Escherichia coli (APEC) Population Structure and Molecular Characteristics.
The study identified multiple antimicrobial resistance genes in Avian Pathogenic Escherichia coli (APEC) isolates, including beta-lactamases (blaCMY-2, blaSHV-12, blaTEM-52, blaCTX-M-1), aminoglycoside resistance genes (aac(3)-IV, aadA, strA, strB, aph(3')-Ib), sulfonamide resistance gene (sul1), tetracycline resistance genes (tet(A), tet(B)), trimethoprim resistance gene (dfrA), quinolone resistance genes (qnrS1, qnrS2, qnrB19), macrolide resistance genes (mph(A), mph(B)), and chloramphenicol resistance gene (catA1).
A One-Health Genomic Investigation of Gentamicin Resistance in Salmonella from Human and Chicken Sources in Canada, 2014 to 2017.
The study identified several aminoglycoside-modifying enzymes, including aac(3)-VIa, aac(3)-IId, aac(3)-Id, aac(3)-IVa, aac(3)-IIa, ant(2′′)-Ia, aac(6′)-Ib-cr, aadA2, aadA7, aadA1, ant(3′′)-Ia, aac(6′)-Ib3, and rmtB, as key contributors to gentamicin resistance in Salmonella isolates from both human and chicken sources in Canada.
Genotypic and Phenotypic Characterization of Antimicrobial Resistance Profiles in Non-typhoidal Salmonella enterica Strains Isolated From Cambodian Informal Markets.
The study identified 17 unique AMR genes in 53% of the 81 S. enterica isolates, including genes encoding resistance to tetracycline, beta-lactam, sulfonamide, quinolone, aminoglycoside, phenicol, and trimethoprim.
IS1294 Reorganizes Plasmids in a Multidrug-Resistant Escherichia coli Strain.
The study identifies and characterizes various AMR genes, including blaCTX-M-55, rmtB, oqxAB, blaTEM-1b, floR, tet(A), strA, strB, sul1, sul2, aac(3)-IId, aadA2, dfrA12, and aph(3′)-IIa, in a multidrug-resistant E. coli strain. These genes contribute to resistance against multiple antibiotics such as beta-lactams, aminoglycosides, fluoroquinolones, tetracyclines, sulfonamides, and trimethoprim.
IS1294 Reorganizes Plasmids in a Multidrug-Resistant Escherichia coli Strain.
The study identifies and characterizes various AMR genes, including blaCTX-M-55, rmtB, oqxAB, blaTEM-1b, floR, tet(A), strA, strB, sul1, sul2, aac(3)-IId, aadA2, dfrA12, and aph(3′)-IIa, in a multidrug-resistant E. coli strain. These genes contribute to resistance against multiple antibiotics such as beta-lactams, aminoglycosides, fluoroquinolones, tetracyclines, sulfonamides, and trimethoprim.
Molecular Epidemiological Analysis of ST11-K64 Extensively Drug-Resistant Klebsiella pneumoniae Infections Outbreak in Intensive Care and Neurosurgery Units Based on Whole-Genome Sequencing.
The study identified multiple AMR genes in ST11-K64 XDRKp strains, including beta-lactamases, aminoglycoside resistance genes, and efflux pumps, contributing to extensive drug resistance.
Genomic Characterization of Endemic and Ecdemic Non-typhoidal Salmonella enterica Lineages Circulating Among Animals and Animal Products in South Africa.
The study identified streptomycin and tetracycline resistance-conferring genes in South African Salmonella enterica lineages, highlighting the presence of antimicrobial resistance in animal and animal product isolates.
Sequence Analyses and Phenotypic Characterization Revealed Multidrug Resistant Gene Insertions in the Genomic Region Encompassing Phase 2 Flagellin Encoding fljAB Genes in Monophasic Variant Salmonella enterica Serovar 4,5,12:i:- Isolates From Various Sources in Thailand.
The study identified multiple multidrug resistance genes, including blaTEM-1B, strA, strB, sul2, and tetB, in Salmonella enterica serovar 4,5,12:i:- isolates from Thailand, which contribute to resistance against ampicillin, streptomycin, sulfonamides, and tetracycline.
Identification of Three Novel PmGRI1 Genomic Resistance Islands and One Multidrug Resistant Hybrid Structure of Tn7-like Transposon and PmGRI1 in Proteus mirabilis.
The study identifies three novel variants of PmGRI1 and a hybrid structure combining Tn7-like transposon and PmGRI1 in Proteus mirabilis, highlighting their role in carrying multiple antibiotic resistance genes.
Identification of Three Novel PmGRI1 Genomic Resistance Islands and One Multidrug Resistant Hybrid Structure of Tn7-like Transposon and PmGRI1 in Proteus mirabilis.
The study identifies three novel variants of PmGRI1 and a hybrid structure combining Tn7-like transposon and PmGRI1 in Proteus mirabilis, highlighting their role in carrying multiple antibiotic resistance genes.
Multidrug Resistance Dynamics in Salmonella in Food Animals in the United States: An Analysis of Genomes from Public Databases.
The study analyzed 22,102 Salmonella genomes from public databases to track antimicrobial resistance (AMR) trends in food animals in the United States. It found that the prevalence of multidrug resistance (MDR) decreased in bovines and swine but increased in poultry. Key AMR genes identified include bla CMY-2, bla CTX-M-65, floR, tetA, sul2, aadA2, aac(3)-VIa, qnrB19, qnrB2, bla SHV-12, bla TEM-1, bla CARB-2, aph(3")-Ib, aph(6)-Id, aph(3')-Ia, ant(3")-Ia, aph(4)-Ia, and aac(3)-IVa. A significant mutation, gyrA D87Y, was associated with quinolone resistance in poultry.
Phylogenetic and antimicrobial drug resistance analysis of Vibrio cholerae O1 isolates from Ghana.
The study identified multiple antimicrobial resistance genes in Vibrio cholerae O1 isolates from Ghana, including strA, strB, catB5, floR, sul2, and dfrA1, which confer resistance to streptomycin, chloramphenicol, florfenicol, sulfonamides, and trimethoprim/sulfamethoxazole. Additionally, mutations in gyrA (S83I) and parC (S85L) were found to contribute to fluoroquinolone resistance.
Whole-Genomic Analysis of NDM-5-Producing Enterobacteriaceae Recovered from an Urban River in China.
The study identified multiple antimicrobial resistance genes, including bla NDM-5, bla OXA-10, and bla TEM-1B, in NDM-5-producing Enterobacteriaceae isolates from an urban river in China. These genes conferred resistance to various antibiotics such as carbapenems, cephalosporins, quinolones, and aminoglycosides.
Discarded masks as hotspots of antibiotic resistance genes during COVID-19 pandemic.
The study identified several antibiotic resistance genes (ARGs) in discarded masks, including aadA-02, mexF, intl-1(clinical), and intl-1LC, which were found to confer resistance to various antibiotics. These genes were detected in both carbon and surgical masks, highlighting the potential of discarded masks as hotspots for antibiotic resistance gene enrichment in marine environments.
Identification of CTX-M Type ESBL E. coli from Sheep and Their Abattoir Environment Using Whole-Genome Sequencing.
The study identified various CTX-M-type beta-lactamase genes, including bla CTX-M-1, bla CTX-M-14, bla CTX-M-15, bla CTX-M-27, bla CTX-M-32, bla CTX-M-55, and bla CTX-M-65, as well as other beta-lactamase genes such as bla TEM-1, bla CARB-2, and bla CMY-2 in ESBL E. coli isolates from sheep and their abattoir environment. Additional AMR genes related to aminoglycosides, macrolides, phenicols, quinolones, sulfonamides, tetracyclines, and trimethoprim were also detected.
Colistin Resistance Onset Strategies and Genomic Mosaicism in Clinical Acinetobacter baumannii Lineages.
The study identifies various AMR genes and mutations associated with colistin resistance in clinical Acinetobacter baumannii strains, highlighting the genomic diversity and mosaicism in resistance mechanisms.
Carbapenem-Resistant Citrobacter spp. as an Emerging Concern in the Hospital-Setting: Results From a Genome-Based Regional Surveillance Study.
The study identifies various carbapenemase genes, including bla KPC-2, bla OXA-48, bla VIM-1, bla NDM-5, bla OXA-162, and bla KPC-3, in Citrobacter spp. isolates, highlighting their role in carbapenem resistance.
Prevalence of genotypic antimicrobial resistance in clinical Shiga toxin-producing Escherichia coli in Norway, 2018 to 2020.
The study identified a low prevalence of genotypic antimicrobial resistance in clinical STEC in Norway, with aminoglycoside resistance being the most common. Key resistance genes included strA, strB, aadA1, sul1, sul2, tetA, blaTEM-1B, and dfrA1.
Genomic comparisons of Escherichia coli ST131 from Australia.
The study identifies multiple AMR genes and mutations in Australian E. coli ST131 isolates, including bla CTX-M-15 and bla CTX-M-27 for beta-lactam resistance, aadA5, strA, strB, mphA, dfrA17, sul1, qacEΔ1, and chrA for resistance to aminoglycosides, macrolides, trimethoprim, sulfonamides, quaternary ammonium compounds, and chromate. Fluoroquinolone resistance mutations in gyrA and parC were also found.
Letter to the Editor: Importation of the First Bovine ST361 New Delhi Metallo-5 Positive Escherichia coli in Greece.
The study reports the first bovine ST361 NDM-5 positive Escherichia coli in Greece, highlighting the importation of multidrug-resistant strains and the need for continued surveillance.
Prevalence and Antimicrobial Resistance Profiles of Foodborne Pathogens Isolated from Dairy Cattle and Poultry Manure Amended Farms in Northeastern Ohio, the United States.
The study identified several antimicrobial resistance genes in foodborne pathogens isolated from dairy cattle and poultry manure amended farms in Northeastern Ohio, including mphA, aadA, aphA1, tetA, aac(3)-IV, sulII, blaTEM, tetB, strA, aac(3)-Iva, ampC, lde, ermB, tet(O), aadB, penA, blaOXA-61, aadE, and aph-3-1.
Outbreak of Multidrug-Resistant Salmonella Heidelberg Infections Linked to Dairy Calf Exposure, United States, 2015-2018.
The study identifies a multidrug-resistant (MDR) Salmonella Heidelberg outbreak linked to dairy calf exposure, highlighting the presence of plasmid-borne resistance genes such as aadA1, aph(3')-Ia, bla CMY-2, floR, fosA7, qnrB19, strA, strB, sull, sul2, tet(A), tet(B), tet(O), and a novel gene dfrA34.
Genomic evolution of the globally disseminated multidrug-resistant Klebsiella pneumoniae clonal group 147.
The study identifies multiple AMR genes and mutations in the pandrug-resistant K. pneumoniae strain DJ, including carbapenemases (bla NDM-5, bla OXA-181, bla CTX-M-15), aminoglycoside resistance genes (rmtB, rmtF, aac(6')-Ib, aadA2, strAB), sulfonamide resistance genes (sul1, sul2), dihydrofolate reductase (dfrA12), polymyxin resistance gene (mgrB), tetracycline resistance gene (ramR), chloramphenicol resistance genes (catA2, catB), fosfomycin resistance gene (fosA), and macrolide resistance genes (mphA, ermB). Mutations in gyrA, parC, ompK35, ompK36, and ramR contribute to resistance to fluoroquinolones, polymyxins, tetracyclines, and other antibiotics.
One Health Genomic Study of Human and Animal Klebsiella pneumoniae Isolated at Diagnostic Laboratories on a Small Caribbean Island.
The study identified various AMR genes in Klebsiella pneumoniae isolates from humans and animals on St. Kitts, including bla CTX-M-15, bla TEM-1b, bla TEM-206, bla OXA-1, and others, highlighting host-specific differences in resistance profiles.
Plethora of Resistance Genes in Carbapenem-Resistant Gram-Negative Bacteria in Greece: No End to a Continuous Genetic Evolution.
The study identified a variety of resistance genes in carbapenem-resistant Gram-negative bacteria, including bla KPC, bla NDM, bla VIM, and others, highlighting the complex genetic diversity of these pathogens.
Plethora of Resistance Genes in Carbapenem-Resistant Gram-Negative Bacteria in Greece: No End to a Continuous Genetic Evolution.
The study identified a variety of resistance genes in carbapenem-resistant Gram-negative bacteria, including bla KPC, bla NDM, bla VIM, and others, highlighting the complex genetic diversity of these pathogens.
Whole-Genome Sequencing of Extended-Spectrum Beta-Lactamase-Producing Escherichia coli From Human Infections in Finland Revealed Isolates Belonging to Internationally Successful ST131-C1-M27 Subclade but Distinct From Non-human Sources.
The study identified several beta-lactamase genes, including bla CTX-M-27, bla CTX-M-15, bla CTX-M-55, bla CTX-M-14, bla CTX-M-3, bla SHV-12, and bla TEM-1, which confer resistance to beta-lactam antibiotics. Other resistance genes such as aadA5, aph(3")-Ib, aph(6)-Id, mph(A), sul1, sul2, tet(A), and dfrA17, dfrA12, dfrA1, and dfrA14 were also characterized, providing insights into the multidrug resistance profiles of ESBL-producing E. coli isolates in Finland.
Mobile Genetic Elements Drive Antimicrobial Resistance Gene Spread in Pasteurellaceae Species.
The study identifies 33 distinct AMR genes associated with mobile genetic elements (MGEs) in Pasteurellaceae species, highlighting the role of MGEs in the spread of antimicrobial resistance.
Virulence and antimicrobial resistance profile of non-typhoidal Salmonella enterica serovars recovered from poultry processing environments at wet markets in Dhaka, Bangladesh.
The study identified several AMR genes in non-typhoidal Salmonella enterica serovars from poultry processing environments in Bangladesh, including bla TEM, tet A, sul 1, and str A/B, which conferred resistance to various antibiotics such as ampicillin, tetracycline, sulfamethoxazole-trimethoprim, and streptomycin.
S. algae as a reservoir and a vehicle of potential antimicrobial resistance
The study identified multiple antimicrobial resistance genes in S. algae strains, including genes conferring resistance to beta-lactams, aminoglycosides, quinolones, phenicols, macrolides, sulfonamides, tetracyclines, and lincosamides.
Genetic diversity and multidrug resistance of phylogenic groups B2 and D in InPEC and ExPEC isolated from chickens in Central China.
The study identifies several AMR genes and mutations in E. coli isolates from chickens in Central China, including aminoglycoside resistance genes strA, strB, and aadA, beta-lactamase genes CTX-M, SHV, OXA, and TEM, and quinolone resistance mutations S83L and D87N in gyrA.
A Genomic and Bioinformatics View of the Classification and Evolution of Morganella Species and Their Chromosomal Accessory Genetic Elements Harboring Antimicrobial Resistance Genes.
The study identified 88 acquired antimicrobial resistance genes (ARGs) in 166 Morganella isolates, with a focus on tetracycline, aminoglycoside, sulfonamide, trimethoprim, and beta-lactam resistance genes. Key ARGs included blaKPC-2, blaNDM-1, aacA4, aadA5, dfrA17, catB3, arr-3, blaOXA-1, aacA4cr, mph(A), rmtB, sul2, floR, qnrS1, tetA, and ermB.
Genomic Analysis of ESBL-Producing E. coli in Wildlife from North-Eastern Germany.
The study identified ESBL-producing E. coli in wild boar and wild ruminants with a low prevalence. The most prevalent ESBL type was CTX-M-1. The study also found resistance genes for aminoglycosides, phenicol, sulfonamides, and tetracyclines.
Comparison of Reference-Based Assembly and De Novo Assembly for Bacterial Plasmid Reconstruction and AMR Gene Localization in Salmonella enterica Serovar Schwarzengrund Isolates.
The study identified various AMR genes in Salmonella enterica serovar Schwarzengrund isolates, including aadA2, AAC(3)-IV, AAC(6')-Iy, APH(4)-Ia, cmlA1, dfrA12, floR, sul1, sul2, sul3, TEM-1, and tet(A). These genes were located on both the chromosome and plasmids, highlighting the importance of plasmid-mediated AMR gene transmission.
Yersinia pestis antibiotic resistance: a systematic review.
Genetic Diversity of Antimicrobial Resistance and Key Virulence Features in Two Extensively Drug-Resistant Acinetobacter baumannii Isolates.
The study identified various AMR genes in two extensively drug-resistant A. baumannii isolates, including aminoglycoside resistance genes, sulfonamide resistance genes, beta-lactamase genes, and efflux pump genes, highlighting the complexity of their resistance mechanisms.
Genetic Characterization of Antibiotic Resistant Enterobacteriaceae Isolates From Bovine Animals and the Environment in Nigeria.
The study characterizes antibiotic resistance genes in Enterobacteriaceae isolates from bovine animals and the environment in Nigeria, identifying several beta-lactamase, aminoglycoside modifying enzymes, qnr, sulfonamide, tetracycline, and trimethoprim resistance genes, highlighting the presence of multidrug-resistant strains.
HAM-ART: An optimised culture-free Hi-C metagenomics pipeline for tracking antimicrobial resistance genes in complex microbial communities.
The study identified various AMR genes, including aadA1, aadA2, blaCFE-1, cmlA1, dfrA12, mdf(A), sul3, tet(34), and lnu(A), in pig fecal microbiomes. Notably, the lnu(A) gene was exclusively found in conventional farms and associated with Lactobacillus species.
Carbapenem-Resistant Acinetobacter baumannii in U.S. Hospitals: Diversification of Circulating Lineages and Antimicrobial Resistance.
The study identifies multiple carbapenemase genes, including blaOXA-23 and blaOXA-207, as well as various resistance islands harboring genes such as aacA4, catB8, and armA, contributing to the multidrug resistance of CR Ab isolates in U.S. hospitals.
Invited Review: Antimicrobial Use and Antimicrobial Resistance in Pathogens Associated with Diarrhea and Pneumonia in Dairy Calves.
The review identified several AMR genes in pathogens associated with calf diarrhea and pneumonia, including beta-lactamases (blaCMY, blaCTX-M, blaTEM), tetracycline resistance genes (tetA, tetB, tetM, tetO), aminoglycoside resistance genes (strA, strB, aadA), sulfonamide resistance genes (sul1, sul2), phenicol resistance genes (cat, floR), and macrolide/lincosamide resistance genes (cfr, ermB).
Genomic Profiling of Antibiotic-Resistant Escherichia coli Isolates from Surface Water of Agricultural Drainage in North-Western Mexico: Detection of the International High-Risk Lineages ST410 and ST617.
The study identified multidrug-resistant Escherichia coli isolates from surface water in north-western Mexico, including international high-risk lineages ST410 and ST617. These isolates carried various AMR genes such as blaTEM-1B, blaCTX-M-15, aadA1, aadA2, aadA5, aac(3)-IIa, aac(3)-IId, aph(3')-Ia, aph(3'')-Ib, aph(6)-Id, floR, cmlA1, lnu(F), mdf(A), sul2, sul3, tet(A), tet(B), dfrA12, and dfrA17. Additionally, mutations in gyrA (S83L, D87N), parC (S80I), and parE (S458A) were found to contribute to fluoroquinolone resistance.
Use of genomics to explore AMR persistence in an outdoor pig farm with low antimicrobial usage.
The study identified various AMR genes in E. coli isolates from a low antimicrobial usage pig farm, highlighting the persistence of multidrug-resistant strains despite minimal selective pressure.
IncFIB-4.1 and IncFIB-4.2 Single-Replicon Plasmids: Small Backbones with Large Accessory Regions.
The study characterizes several AMR genes and mutations in IncFIB-4.1 and IncFIB-4.2 plasmids, highlighting their role in conferring resistance to various antibiotics.
Antimicrobial resistance determinants in silage.
The study identified 16 antimicrobial resistance genes (ARGs) in silage samples, highlighting their potential to spread through the food chain and contribute to antimicrobial resistance.
Relationship and distribution of Salmonella enterica serovar I 4,[5],12:i:- strain sequences in the NCBI Pathogen Detection database.
The study identified the presence of the MDR module and SGI-4 in Salmonella enterica serovar I 4,[5],12:i:- strains, which confer resistance to multiple antimicrobial classes including ampicillin, streptomycin, sulfisoxazole, and tetracycline.
Using whole-genome sequence data to examine the epidemiology of antimicrobial resistance in Escherichia coli from wild meso-mammals and environmental sources on swine farms, conservation areas, and the Grand River watershed in southern Ontario, Canada.
The study identified several AMR genes in E. coli isolates from wild meso-mammals and environmental sources, including blaTEM-1, tet(A), tet(B), sul1, sul2, aph(3”)-Ib, aph(6)-Id, blaCMY-2, qnrS1, and floR. These genes conferred resistance to various antibiotics such as beta-lactams, tetracyclines, sulfonamides, aminoglycosides, and quinolones.
Epidemiology of Klebsiella michiganensis Carrying Multidrug-Resistant IncHI5 Plasmids in the Southeast Coastal Area of China.
The study identified multiple AMR genes on IncHI5 plasmids in Klebsiella michiganensis, including beta-lactamases (blaCTX-M-3, blaTEM-1, blaSHV-12, blaIMP-4, blaNDM-1, blaOXA-1, blaOXA-16, blaSFO-1, blaSIM-1), aminoglycoside modifying enzymes (aacA4, arr3, aadA5, gcu37, dfrA1), chloramphenicol acetyltransferase (catA2), streptomycin resistance genes (strA, strB), macrolide resistance genes (msrAB, mph(A)), and quaternary ammonium compound resistance gene (qacG2).
Wild Duck (Anas platyrhynchos) as a Source of Antibiotic-Resistant Salmonella enterica subsp. diarizonae The First Report in Poland.
The study identified the presence of aadA, strA/strB, and blaTEM genes in a multidrug-resistant Salmonella enterica subsp. diarizonae strain isolated from a wild mallard duck in Poland.
Characterization of Klebsiella pneumoniae isolated from patients suspected of pulmonary or bubonic plague during the Madagascar epidemic in 2017.
The study identified several AMR genes in K. pneumoniae isolates, including bla CTX-M-15, bla SHV-27, bla SHV-1, bla SHV-101, bla SHV-108, bla TEM-1B, qnrB66, aac(3)-IIa, dfrA14, strA, strB, sul2, and tet(A). These genes conferred resistance to various antibiotics such as beta-lactams, quinolones, aminoglycosides, sulfonamides, and tetracyclines.
Genetic Characterization of Four Groups of Chromosome-Borne Accessory Genetic Elements Carrying Drug Resistance Genes in Providencia.
This study characterizes four groups of chromosome-borne accessory genetic elements (AGEs) in Providencia, highlighting the diversity and complexity of multidrug resistance (MDR) regions within these elements. It identifies numerous drug resistance genes, including beta-lactamases, aminoglycoside modifying enzymes, tetracycline resistance genes, and others, contributing to the understanding of AMR mechanisms in Providencia.
Analysis of Salmonella enterica Isolated from a Mixed-Use Watershed in Georgia, USA: Antimicrobial Resistance, Serotype Diversity, and Genetic Relatedness to Human Isolates.
The study identified multiple antimicrobial resistance genes in Salmonella enterica isolates from a mixed-use watershed in Georgia, USA, including bla CMY-2, aadA2, strA, strB, sul1, sul2, tetA, tetC, floR, and dfrA12, which conferred resistance to various antibiotics such as ceftiofur, ceftriaxone, streptomycin, sulfisoxazole, tetracycline, chloramphenicol, and trimethoprim.
Analysis of Salmonella enterica Isolated from a Mixed-Use Watershed in Georgia, USA: Antimicrobial Resistance, Serotype Diversity, and Genetic Relatedness to Human Isolates.
The study identified multiple antimicrobial resistance genes in Salmonella enterica isolates from a mixed-use watershed in Georgia, USA, including bla CMY-2, aadA2, strA, strB, sul1, sul2, tetA, tetC, floR, and dfrA12, which conferred resistance to various antibiotics such as ceftiofur, ceftriaxone, streptomycin, sulfisoxazole, tetracycline, chloramphenicol, and trimethoprim.
Epidemiology, Environmental Risks, Virulence, and Resistance Determinants of Klebsiella pneumoniae From Dairy Cows in Hubei, China.
The study identified several AMR genes in K. pneumoniae isolates from dairy cows in Hubei, China, including blaTEM, blaSHV, strA, strB, aadA1, and aac(6')-Ib-cr, which contribute to resistance against various antibiotics.
Antimicrobial Resistance in Acinetobacter spp. Isolated from Pet Reptiles
The study identified various AMR genes in Acinetobacter spp. isolated from pet reptiles, including tetracycline, sulfonamide, and aminoglycoside resistance genes, highlighting the presence of multidrug-resistant strains in these animals.
Escherichia coli ST1193: Following in the Footsteps of E. coli ST131
The paper characterizes Escherichia coli ST1193 as an emerging multidrug-resistant clone with various AMR determinants, including beta-lactamases (bla CTX-M-15, bla CTX-M-14, bla CTX-M-27, bla CTX-M-55, bla OXA-1, bla TEM-1, bla CMY-42, bla CMY-2), aminoglycoside-modifying enzymes (aac(3)-IIa, aac(3)-IId, aac(6′)-Ib-cr, aadA1, aadA2, aadA5, aph(3′′)-Ib, aph(6)-Id), and other resistance genes (mcr-1, mph(A), erm(B), dfrA8, dfrA12, dfrA17, sul1, sul2, tetA, tetB).
Occurrence of bla(NDM-1)-Positive Providencia spp. in a Pig Farm of China.
Four bla NDM-1-positive Providencia strains were identified in a pig farm in China, showing multidrug resistance and carrying additional resistance genes such as bla OXA-10, bla TEM-116, and others.
Occurrence of antibiotics and bacterial resistance genes in wastewater: resistance mechanisms and antimicrobial resistance control approaches.
The study identifies several AMR genes and mutations associated with resistance to various antibiotics in wastewater environments, highlighting the role of these genes in the spread of antimicrobial resistance.
Genomic and Evolutionary Analysis of Salmonella enterica Serovar Kentucky Sequence Type 198 Isolated From Livestock In East Africa.
The study identified multiple antimicrobial resistance genes in Salmonella enterica serovar Kentucky ST198 isolates from East Africa, including aac(3)-Id, aadA7, strA, strB, bla TEM-1B, sul1, and tet(A), which confer resistance to aminoglycosides, streptomycin, ampicillin, sulfamethoxazole, and tetracycline. Mutations in gyrA and parC were associated with ciprofloxacin resistance.
Genomic surveillance for multidrug-resistant or hypervirulent Klebsiella pneumoniae among United States bloodstream isolates.
The study identified various antimicrobial resistance genes and mutations in Klebsiella pneumoniae bloodstream isolates, highlighting the presence of multidrug-resistant and hypervirulent strains in the United States.
Genomic surveillance for multidrug-resistant or hypervirulent Klebsiella pneumoniae among United States bloodstream isolates.
The study identified various antimicrobial resistance genes and mutations in Klebsiella pneumoniae bloodstream isolates, highlighting the presence of multidrug-resistant and hypervirulent strains in the United States.
Characterization of NDM-5 Carbapenemase-Encoding Gene (bla (NDM-5)) - Positive Multidrug Resistant Commensal Escherichia coli from Diarrheal Patients.
The study characterizes the bla NDM-5 gene in multidrug-resistant commensal E. coli from diarrheal patients, highlighting its resistance to various antibiotics and its potential for horizontal transfer.
Distribution of ESBL/AmpC-Escherichia coli on a Dairy Farm.
The study identified ESBL/AmpC-producing E. coli on a dairy farm, with a high prevalence in calves. Key resistance genes included blaCTX-M-1, blaCTX-M-15, floR, strA, strB, catA, aadA, dfrA, tetA, tetR, tetY, mph(A), and TEM-105.
Molecular Characterization of pBOq-IncQ and pBOq-95LK Plasmids of Escherichia coli BOq 01, a New Isolated Strain from Poultry Farming, Involved in Antibiotic Resistance.
The study characterizes two plasmids, pBOq-IncQ and pBOq-95LK, in the multidrug-resistant E. coli strain BOq 01. pBOq-IncQ carries genes for resistance to sulfonamides and streptomycin, while pBOq-95LK encodes a bleomycin hydrolase, providing resistance to bleomycin. The plasmid pBOq-95LK is a phage-like plasmid that may contribute to the spread of antibiotic resistance genes.
Molecular characterization of extended spectrum cephalosporin resistant Escherichia coli isolated from livestock and in-contact humans in Southeast Nigeria.
The study identified four variants of bla CTX-M (CTX-M-15, CTX-M-55, CTX-M-64, and CTX-M-65) in extended-spectrum cephalosporin-resistant Escherichia coli from livestock and in-contact humans in Southeast Nigeria. Other AMR genes such as bla TEM-1b, aac 3-IId, qnr S1, and sul 2 were also characterized.
Molecular characterization of extended spectrum cephalosporin resistant Escherichia coli isolated from livestock and in-contact humans in Southeast Nigeria.
The study identified four variants of bla CTX-M (CTX-M-15, CTX-M-55, CTX-M-64, and CTX-M-65) in extended-spectrum cephalosporin-resistant Escherichia coli from livestock and in-contact humans in Southeast Nigeria. Other AMR genes such as bla TEM-1b, aac 3-IId, qnr S1, and sul 2 were also characterized.
Serotype Diversity and Antimicrobial Resistance Profile of Salmonella enterica Isolates From Freshwater Turtles Sold for Human Consumption in Wet Markets in Hong Kong.
The study identifies the multidrug-resistance gene cfr for the first time in Salmonella, highlighting the expansion of the cfr reservoir and potential horizontal spread to other bacteria. It also detects various AMR genes such as floR, sul2, aph(3')-Ia, aph(3”)-Ib, aph(6)-Id, aac(6')-Ib-cr, bla CMY−2, bla TEM−1, qnrS1, erm(B), mph(E), msr(E), qepA8, arr-3, sul1, dfrA12, dfrA27, tet(A), tet(D), catB3, aadA16, aac(3)-IV, aph(4)-Ia, aadA2, and fosA7.
Molecular characterisation of Acinetobacter baumannii isolates from bloodstream infections in a tertiary-level hospital in South Africa.
The study identified colistin-resistant Acinetobacter baumannii isolates with resistance genes including bla OXA-23, bla NDM-1, lps B, and various efflux pumps. These isolates exhibited extensive drug resistance (XDR) and were associated with sequence types ST1 and ST2.
Emergence, Dissemination and Antimicrobial Resistance of the Main Poultry-Associated Salmonella Serovars in Brazil.
The study characterizes antimicrobial resistance (AMR) genes and mutations in various Salmonella serovars associated with poultry in Brazil, emphasizing the emergence of multidrug-resistant (MDR) strains. Key findings include the identification of AMR genes such as blaCTX-M-2, blaTEM-1B, aac(3)-lla, aac(3)-lld, aadA1, aadA2, aph(6)-ld, dfrA1, floR, mrc-1, strA, strB, sul1, sul2, tet(A), tet(B), and others, which confer resistance to multiple antibiotics.
Emergence, Dissemination and Antimicrobial Resistance of the Main Poultry-Associated Salmonella Serovars in Brazil.
The study characterizes antimicrobial resistance (AMR) genes and mutations in various Salmonella serovars associated with poultry in Brazil, emphasizing the emergence of multidrug-resistant (MDR) strains. Key findings include the identification of AMR genes such as blaCTX-M-2, blaTEM-1B, aac(3)-lla, aac(3)-lld, aadA1, aadA2, aph(6)-ld, dfrA1, floR, mrc-1, strA, strB, sul1, sul2, tet(A), tet(B), and others, which confer resistance to multiple antibiotics.
Identification and Characterisation of pST1023 A Mosaic, Multidrug-Resistant and Mobilisable IncR Plasmid.
The study identifies and characterizes the mosaic, multidrug-resistant, and mobilizable IncR plasmid pST1023, which carries several AMR genes including cmlA1, aadA1, aadA2, sul3, tetA(B), dfrA12, and a sil operon conferring resistance to various antibiotics and silver.
Emergence and multi-lineages of carbapenemase-producing Acinetobacter baumannii-calcoaceticus complex from canine and feline origins.
The study identifies blaOXA-23 as a prevalent carbapenemase gene in carbapenem-resistant Acinetobacter baumannii-calcoaceticus complex isolates from dogs and cats in Thailand. Additionally, several tetracycline and aminoglycoside resistance genes, including tet(B), tet(39), strA, strB, aac(3)-Ia, aac(3)-IIa, aac(6')-Im, aac(6')-Ib, ant(2'')-Ia, and aph(3')-VI, were detected.
Dynamics of Genotypic and Phenotypic Antibiotic Resistance in a Conventional Wastewater Treatment Plant in 2 Years.
The study identified several AMR genes, including beta-lactamases (bla TEM, bla CTX-M-1, bla OXA-1), aminoglycoside resistance genes (strA, strB), sulfonamide resistance genes (sul1, sul2), and tetracycline resistance gene (tetA), in multidrug-resistant bacteria within a wastewater treatment plant over two years.
Comparative Analysis of Clinical and Genomic Characteristics of Hypervirulent Klebsiella pneumoniae from Hospital and Community Settings: Experience from a Tertiary Healthcare Center in India.
The study identified multiple AMR genes, including bla CTX-M-15, bla SHV, bla OXA, and bla NDM, in hypervirulent Klebsiella pneumoniae isolates from both hospital and community settings, highlighting the emergence of multidrug-resistant hvKp strains.
Genomic insight into the integrative conjugative elements from ICEHpa1 family.
The study identifies four novel ICEHpa1 variants (ICE Gpa1818, ICE Gpa1808, ICE Gpa1807, and ICE Gpa1815) carrying diverse resistance genes, including tetracycline, streptomycin, gentamicin, sulfamethoxazole/trimethoprim, florfenicol, and amoxicillin resistance genes.
Urban rats as carriers of invasive Salmonella Typhimurium sequence type 313, Kisangani, Democratic Republic of Congo.
The study identified multidrug-resistant Salmonella Typhimurium ST313 in urban rats in Kisangani, Democratic Republic of Congo, highlighting their potential role as reservoirs of invasive Salmonella. The resistant isolates carried genes such as blaTEM-1, strA, strB, ant(3')-Ia, aac(3')-IId, sul1, sul2, dfrA1, tetB, and catA10, conferring resistance to multiple antibiotics.
Molecular epidemiology and antibiotic resistance profiles of invasive Haemophilus influenzae from Norway 2017-2021.
The study identified bla TEM–1, rPBP3, catA2, tet(B), sul2, aph(3')-Ia, strA, and strB as significant antibiotic resistance genes in invasive Haemophilus influenzae isolates from Norway. Mutations in PBP3, GyrA, and ParC were also associated with resistance to beta-lactams and quinolones.
Genomic Analysis of Shiga Toxin-Producing E. coli O157 Cattle and Clinical Isolates from Alberta, Canada.
The study identified eight antimicrobial resistance gene cassettes (ARCs) in 14 isolates, with streptomycin resistance genes (aadA1, aadA2, ant(3'')-Ia, and aph(3'')-Ib) being the most prevalent. Other resistance genes included sul1, sul2, tet(A), tet(B), and beta-lactam resistance genes (blaTEM-1B and blaTEM-1C).
Occurrence of Antimicrobial-Resistant Escherichia coli in Marine Mammals of the North and Baltic Seas: Sentinels for Human Health.
The study identified antimicrobial-resistant Escherichia coli in marine mammals from the North and Baltic Seas, highlighting the presence of resistance genes such as blaTEM, strA, strB, aadA1, sul1, sul2, tet(A), tet(B), tet(D), qnrS, floR, catA1, blaOXA-1-like, blaSHV, and blaCMY-2.
Phage-Plasmids Spread Antibiotic Resistance Genes through Infection and Lysogenic Conversion.
Phage-plasmids (P-Ps) carry a variety of antibiotic resistance genes (ARGs), including beta-lactamases, aminoglycoside-modifying enzymes, and carbapenemases. These genes are often located in integrons and are associated with transposable elements. P-Ps can be induced by mitomycin C and can transfer resistance genes through lysogenic conversion.
Emergence of Extensively Drug-Resistant ST170 Citrobacter portucalensis with Plasmids pK218-KPC, pK218-NDM, and pK218-SHV from a Tertiary Hospital, China.
The study identifies the emergence of an extensively drug-resistant Citrobacter portucalensis strain, K218, which carries multiple resistance genes including bla KPC-2 and bla NDM-1, contributing to its multidrug-resistant phenotype.
A One Health Genomic Investigation of Gentamicin Resistance in Escherichia coli from Human and Chicken Sources in Canada, 2014 to 2017.
The study identified several aminoglycoside-modifying enzymes, including aac(3)-IId, aac(3)-VIa, aac(3)-IIa, aac(6′)-Ib-cr, aac(3)-IVa, ant(2″)-Ia, aadA5, aadA1, aadA2, aph(3″)-Ib, and strA, as key contributors to gentamicin and spectinomycin resistance in Escherichia coli from human and chicken sources in Canada.
A One Health Genomic Investigation of Gentamicin Resistance in Escherichia coli from Human and Chicken Sources in Canada, 2014 to 2017.
The study identified several aminoglycoside-modifying enzymes, including aac(3)-IId, aac(3)-VIa, aac(3)-IIa, aac(6′)-Ib-cr, aac(3)-IVa, ant(2″)-Ia, aadA5, aadA1, aadA2, aph(3″)-Ib, and strA, as key contributors to gentamicin and spectinomycin resistance in Escherichia coli from human and chicken sources in Canada.
Mobile genetic elements in Acinetobacter antibiotic-resistance acquisition and dissemination.
The study highlights the role of mobile genetic elements, particularly insertion sequences (IS), in the acquisition and dissemination of antibiotic resistance in Acinetobacter species. IS elements can enhance the expression of intrinsic beta-lactamase genes, such as bla OXA-23, bla OXA-51, and ampC, leading to carbapenem and cephalosporin resistance. Additionally, IS elements can disrupt genes involved in antibiotic uptake, such as porins, and alter the expression of efflux pumps, contributing to multidrug resistance.
Incidence of antibiotic resistance genotypes of Vibrio species recovered from selected freshwaters in Southwest Nigeria.
The study identified multiple antibiotic resistance genes in Vibrio species from freshwater samples in Southwest Nigeria, including sulI, sulII, ampC, blaOXA, blaPSE, tetA, tetE, strA, aacC2, and aphA1, highlighting the environmental spread of resistance genes.
Genomic Study of Chromosomally and Plasmid-Mediated Multidrug Resistance and Virulence Determinants in Klebsiella Pneumoniae Isolates Obtained from a Tertiary Hospital in Al-Kharj, KSA.
The study identified several AMR genes in K. pneumoniae isolates, including blaOXA-1, blaCTX-M-3, blaOXA-232, catB3, aac(6')-Ib-cr, dfrA14, IntI1, IS1, RepE, qnrB4, qnrB55, qnrS1, aph(3")-Ib, sul2, aadA2, SHV-190, SHV-26, SHV-11, tet(A), fosA, OqxA, and OqxB, which confer resistance to various antibiotics such as beta-lactams, aminoglycosides, trimethoprim, quinolones, sulfonamides, and fosfomycin.
Conjugative transfer of multi-drug resistance IncN plasmids from environmental waterborne bacteria to Escherichia coli.
The study identified the transfer of multi-drug resistance IncN plasmids from environmental waterborne bacteria to E. coli, highlighting the presence of sulfonamide resistance genes sul1 and sul2 in transconjugants.
Antimicrobial resistance and associated genetic background of Histophilus somni isolated from clinically affected and healthy cattle.
The study identified several AMR genes in Histophilus somni isolates, including bla ROB - 1, aphA-1, strA, strB, tetH, and tetR, which are associated with resistance to ampicillin, amoxicillin, kanamycin, streptomycin, and oxytetracycline. These genes were found in isolates from respiratory diseases and were linked to increased MICs.
Antimicrobial resistance and genomic characterization of Salmonella enterica serovar Senftenberg isolates in production animals from the United States.
The study characterized antimicrobial resistance genes and mutations in Salmonella enterica serovar Senftenberg isolates from production animals in the United States, identifying genes such as aac(6')-Iaa, aph(3")-Ib, aph(6)-Id, blaTEM-1B, blaCMY-2, blaSHV-12, floR, catA2, qnrB2, aac(6')-Ib-cr, aadA1, aadA2, sul1, sul2, tetA, and mcr-9.1, along with mutations in gyrA and parC genes contributing to resistance against various antibiotics.
The hazard of carbapenemase (OXA-181)-producing Escherichia coli spreading in pig and veal calf holdings in Italy in the genomics era: Risk of spill over and spill back between humans and animals.
The study identifies multiple AMR genes, including bla OXA-181, bla TEM-1B, aac (3)-IId, aad A2, cml A1, dfr A12, mef (B), sul 3, tet (A), tet (M), incX3, incX1, incFII, qnr S1, aph (3″)-Ib, aph (6)-Id, flo R, lnu (F), sul 2, sul 3, tet (B), mph (A), mph (G), qnr B4, rmt B, and fos A3, in OXA-181-producing E. coli isolates from pigs and bovines in Italy. These genes confer resistance to various antibiotics, including carbapenems, cephalosporins, penicillins, aminoglycosides, trimethoprim, macrolides, sulfonamides, tetracyclines, fluoroquinolones, and fosfomycin.
Diversity of resistant determinants, virulence factors, and mobile genetic elements in Acinetobacter baumannii from India: A comprehensive in silico genome analysis.
The study identified multiple antibiotic resistance genes (ARGs) in 47 Acinetobacter baumannii isolates from India, including blaOXA-23, blaADC-73, aac(3)-I, aadA, aph(3')-Ib, sul1, sul2, and lpsB. These genes contribute to resistance against carbapenems, cephalosporins, aminoglycosides, sulfonamides, and polymyxins.
Molecular Epidemiology of Antimicrobial Resistance and Virulence Profiles of Escherichia coli, Salmonella spp., and Vibrio spp. Isolated from Coastal Seawater for Aquaculture.
The study identified several AMR genes, including blaTEM, tetA, qnrS, strA, and floR, in Escherichia coli, Salmonella spp., and Vibrio spp. isolates from coastal seawater in Thailand. These genes conferred resistance to various antibiotics such as ampicillin, tetracycline, fluoroquinolones, streptomycin, and chloramphenicol.
In Vitro Assessment of Antimicrobial Activity of Phytobiotics Composition towards of Avian Pathogenic Escherichia coli (APEC) and Other E. coli Strains Isolated from Broiler Chickens.
The study identifies several AMR genes in E. coli strains, including aadA, strA/strB, aphA1, aphA2, tetA, tetB, sul1, sul2, sul3, dfrA1, dfrA10, dfrA12, floR, and blaSHV, which confer resistance to various antibiotics such as streptomycin, neomycin, tetracycline, sulfonamides, trimethoprim, chloramphenicol, and cephalosporins.
Resistome and virulome diversity of foodborne pathogens isolated from artisanal food production chain of animal origin in the Mediterranean region.
The study identified various AMR genes in L. monocytogenes, Salmonella enterica, and S. aureus isolates from artisanal food production chains in the Mediterranean region, highlighting the presence of fosfomycin, aminoglycoside, beta-lactam, trimethoprim, sulfonamide, tetracycline, and streptomycin resistance mechanisms.
Molecular and Clinical Characteristics of Carbapenem-Resistant Klebsiella pneumoniae Isolates at a Tertiary Hospital in Wuhan, China.
The study identified multiple carbapenem-resistant Klebsiella pneumoniae (CRKP) isolates carrying various resistance genes, including blaKPC-1, blaCTX-M-65, blaTEM-1, blaSHV-182, rmtB, aadA2, APH(3')-Ia, sul1, sul2, QnrS1, mphA, FosA6, floR, and tet(A). These genes confer resistance to carbapenems, beta-lactams, aminoglycosides, sulfonamides, fluoroquinolones, macrolides, fosfomycin, chloramphenicol, and tetracyclines.
Molluscs-A ticking microbial bomb.
The paper discusses the presence of antibiotic resistance genes (ARGs) in bivalve molluscs, highlighting the spread of resistance to various antibiotics such as colistin, beta-lactams, fluoroquinolones, and tetracyclines. It emphasizes the role of bivalve aquacultures in the dissemination of ARGs and the potential risks to human health through the food chain.
Combining analytical epidemiology and genomic surveillance to identify risk factors associated with the spread of antimicrobial resistance in Salmonella enterica subsp. enterica serovar Heidelberg.
The study identified multiple AMR genes in Salmonella enterica subsp. enterica serovar Heidelberg, including bla CMY-2, bla TEM-1A, bla TEM-1B, bla TEM-214, mcr -9, and others, highlighting the prevalence of resistance to beta-lactams, aminoglycosides, and other antimicrobial agents.
Combining analytical epidemiology and genomic surveillance to identify risk factors associated with the spread of antimicrobial resistance in Salmonella enterica subsp. enterica serovar Heidelberg.
The study identified multiple AMR genes in Salmonella enterica subsp. enterica serovar Heidelberg, including bla CMY-2, bla TEM-1A, bla TEM-1B, bla TEM-214, mcr -9, and others, highlighting the prevalence of resistance to beta-lactams, aminoglycosides, and other antimicrobial agents.
The fate of sulfonamide resistance genes and anthropogenic pollution marker intI1 after discharge of wastewater into a pristine river stream.
The study identifies and characterizes several sulfonamide resistance genes (sul1, sul2), the integrase gene intI1, and various other antibiotic resistance genes (ARGs) such as aadA2, aadA11, blaOXA-2, blaOXA-4, blaOXA-10, blaOXA-33, blaOXA-36, blaOXA-129, blaOXA-392, blaOXA-824, blaBEL-1, blaGES-11, ereA2, cmlA5, dfrA1, and qacL. These genes were found in the class 1 integron gene cassettes in the Holtemme river, highlighting the persistence of ARGs downstream from wastewater treatment plant discharge.
In silico analyses of diversity and dissemination of antimicrobial resistance genes and mobile genetics elements, for plasmids of enteric pathogens.
The study identifies a diverse array of antimicrobial resistance (AMR) genes across various plasmid replicon types in enteric pathogens, highlighting the prevalence of resistance genes in plasmids such as IncHI2, IncN, IncA/C, IncP, IncHI1, and IncFIA. Key AMR genes include aac(3)-IId, aac(3)-IIg, aac(6')-Ib3, aadA1, aadA5, aph(3'')-Ib, bla CMY-2, bla CTX-M-27, bla NDM-1, mcr-9.1, and others, which confer resistance to antibiotics such as gentamicin, cephalosporins, carbapenems, colistin, and tetracycline.
Silver nanoparticles enhance the efficacy of aminoglycosides against antibiotic-resistant bacteria.
The study identifies several AMR genes, including mcr-1, mcr-3, mcr-4, aadA5, catA1, bla CMY-2, bla CTX-M-55, dfrA17, fosA, mph(A), rmtB, strA, strB, sul1, sul2, bla TEM-1B, and bla CMY-48, which confer resistance to various antibiotics in different bacterial strains.
Epidemiology and Genetic Characteristics of Carbapenem-Resistant Escherichia coli in Chinese Intensive Care Unit Analyzed by Whole-Genome Sequencing: a Prospective Observational Study.
The study identified bla KPC-2 and bla NDM-5 as the main carbapenem resistance genes in carbapenem-resistant Escherichia coli (CREC) isolates. Additionally, various other resistance genes were detected, including extended-spectrum beta-lactamases (CTX-M-14, CTX-M-15, CTX-M-27, CTX-M-3, OXA-1, OXA-10, TEM-1), aminoglycoside resistance genes (aac(3)-IId, aac(3)-Iva, aac(6′)-Ib-AKT, aac(6′)-Ib-D181Y, aadA1, aadA2, aadA5, aph(3″)-Ib, aph(3′)-Ia, aph(4)-Ia, aph(6)-Id), quinolone resistance genes (qnrS1, qnrS2), tetracycline resistance genes (oqxA10, oqxB17), fosfomycin resistance gene (fosA3), and chloramphenicol resistance genes (cmlA1, cmlA5).
Molecular and Antimicrobial Susceptibility Characterization of Escherichia coli Isolates from Bovine Slaughterhouse Process.
The study identified several AMR genes including tetA, strB, aadA, tetB, aac(3)IV, and strA in E. coli isolates from bovine slaughterhouse samples, highlighting the prevalence of tetracycline and streptomycin resistance.
Genetic Organization of Acquired Antimicrobial Resistance Genes and Detection of Resistance-Mediating Mutations in a Gallibacterium anatis Isolate from a Calf Suffering from a Respiratory Tract Infection.
The study identified multiple acquired antimicrobial resistance genes and resistance-mediating mutations in a Gallibacterium anatis isolate from a calf with a respiratory tract infection, highlighting the potential for this bacterium to serve as a reservoir for antimicrobial resistance genes.
Integrative omics identifies conserved and pathogen-specific responses of sepsis-causing bacteria.
The study identified various AMR genes in sepsis-causing bacteria, including beta-lactamases, aminoglycoside-modifying enzymes, tetracycline resistance genes, and others, highlighting the complexity of AMR in these pathogens.
Prevalence and Characterization of Salmonella Isolated from Chickens in Anhui, China.
The study identified several AMR genes in Salmonella isolates from chickens in Anhui, China, including blaTEM, blaCMY-2, aadA, strA, aph(3')-IIa, aac(6')-Ib-cr, qnrB, qnrS, sul1, sul2, tetA, tetB, cat1, and floR. These genes were associated with resistance to various antibiotics such as ampicillin, cephalosporins, streptomycin, gentamicin, amikacin, fluoroquinolones, sulfamethoxazole, tetracycline, chloramphenicol, and florfenicol.
Prevalence and Genomic Characteristics of mcr-Positive Escherichia coli Strains Isolated from Humans, Pigs, and Foods in China.
The study identified mcr-1 as a major gene conferring colistin resistance in Escherichia coli isolates from humans, pigs, and foods in China. Additionally, several other resistance genes such as tet(A), floR, sul2, aadA1, strA, strB, blaCTX-M-14, fosA, lnu(F), and arr-3 were found to confer resistance to various antibiotics.
High Genetic Diversity of Carbapenem-Resistant Acinetobacter baumannii Isolates Recovered in Nigerian Hospitals in 2016 to 2020.
The study identified blaOXA-23 and blaNDM-1 as the most common carbapenem resistance genes in Acinetobacter baumannii isolates from Nigerian hospitals, along with several other AMR genes and mutations contributing to multidrug resistance.
Brevundimonas brasiliensis sp. nov.: a New Multidrug-Resistant Species Isolated from a Patient in Brazil.
The study characterizes Brevundimonas brasiliensis sp. nov., a novel species isolated from a neonatal intensive care unit, and identifies several antimicrobial resistance genes and mutations associated with resistance to β-lactams, aminoglycosides, fluoroquinolones, and colistin.
Phylogenomics of Globally Spread Clonal Groups 14 and 15 of Klebsiella pneumoniae.
The study characterizes various AMR genes and mutations in K. pneumoniae clonal groups 14 and 15, highlighting the prevalence of bla CTX-M-15, bla OXA-232, bla NDM-1, and other beta-lactamases, along with quinolone resistance mechanisms.
A Nationwide Genomic Study of Clinical Klebsiella pneumoniae Carrying bla(OXA-232) and rmtF in China.
The study characterizes the AMR genes blaOXA-232 and rmtF in OXA-232-producing Klebsiella pneumoniae isolates in China, along with other resistance genes such as blaCTX-M-15, blaTEM-1B, aacA4'-17, aadA2, arr-2, qnrB1, and qnrS1. Mutations in gyrA and parC contribute to fluoroquinolone resistance.
Antibiotic-Resistant Vibrio cholerae O1 and Its SXT Elements Associated with Two Cholera Epidemics in Kenya in 2007 to 2010 and 2015 to 2016.
The study identified antibiotic resistance genes dfrA1, sul2, strA, strB, and floR in Vibrio cholerae O1 strains from two cholera epidemics in Kenya. Chromosomal mutations in gyrA (Ser83Ile) and parC (Ser85Leu) were associated with nalidixic acid resistance.
Virotyping and genetic antimicrobial susceptibility testing of porcine ETEC/STEC strains and associated plasmid types.
The study identified several AMR genes and mutations in porcine ETEC/STEC strains, including beta-lactamases (blaTEM-1A, blaTEM-1B, blaTEM-106), polymyxin resistance genes (mcr-1.1, mcr-2.1, mcr-5.1), aminoglycoside resistance genes (aac(3)-IId, aac(3)-IV, aac(3)-IVa, aph(3')-Ia, aadA1, aadA10, aadA12), florfenicol resistance gene (floR), tetracycline resistance genes (tet(A), tet(B)), quinolone resistance gene (qnrS1), and trimethoprim-sulfamethoxazole resistance genes (dfrA1, dfrA5, dfrA12, dfrA14, dfrA36).
Pathogen genomics and phage-based solutions for accurately identifying and controlling Salmonella pathogens.
The study identified various AMR genes in Salmonella isolates from the UK and Thailand, highlighting the prevalence of resistance to multiple antibiotics, particularly in certain serovars like S. Typhimurium and S. 1,4,[5],12:i:-. Key AMR genes included bla TEM-1b, bla CARB-2, bla TEM-135, bla TEM-1D, mphB, cmlA1, floR, gyrA, qnrS1, aac(3)-Id, aac(3)-IVa, strA, strB, sul1, sul2, sul3, tetA(B), tet(A), tet(G), tet(M), and dfrA12.
Genomic Surveillance of Salmonella from the Comunitat Valenciana (Spain).
The study identified multiple antimicrobial resistance genes including mcr-1, tet(A), aadA2, dfrA12, sul1, sul3, and ant(3")-Ia, along with mutations in gyrA that confer resistance to various antibiotics in Salmonella isolates from the Comunitat Valenciana, Spain.
The First Report of Escherichia coli and Klebsiella pneumoniae Strains That Produce Both NDM-5 and OXA-181 in Jiangsu Province, China.
The study reports the first identification of Escherichia coli and Klebsiella pneumoniae strains producing both NDM-5 and OXA-181 carbapenemases in pediatric patients in China, highlighting the potential for rapid dissemination of these resistance genes.
Clinical and Bacterial Characteristics Associated with Glove and Gown Contamination by Carbapenem-Resistant Klebsiella pneumoniae in the Health Care Setting.
The study identified various carbapenem resistance genes such as bla KPC, bla KPC-3, bla KPC-2, bla NDM, and bla OXA-232, as well as aminoglycoside resistance genes like aph(6)-Id, aph(3″)-Ib, and others. It also found sulfonamide resistance genes (sul1, sul2, sul3), beta-lactam resistance genes (bla TEM, bla OXA), and quinolone resistance genes (qnrS1).
Whole-Genome Sequencing Revealed the Fusion Plasmids Capable of Transmission and Acquisition of Both Antimicrobial Resistance and Hypervirulence Determinants in Multidrug-Resistant Klebsiella pneumoniae Isolates.
The study identified multiple antimicrobial resistance genes and hypervirulence determinants in multidrug-resistant Klebsiella pneumoniae isolates, highlighting the role of fusion plasmids in the transmission of these traits.
Role of multidrug resistance and co-resistance on a high percentage of streptomycin resistance in Escherichia coli isolated from chicken meats in Japan.
The study identifies multiple AMR genes, including strA/strB, blaTEM, tetB, aphA1, dfrA14, dfrA17, and cat1, which contribute to multidrug resistance in Escherichia coli isolated from chicken meats in Japan.
Antimicrobial resistance in bacteria isolated from peridomestic Rattus species: A scoping literature review.
This scoping review identifies various antimicrobial resistance (AMR) genes in bacteria isolated from peridomestic Rattus species, including beta-lactamases (bla TEM, bla CTX-M, bla SHV, bla VIM, bla IMP, bla NDM-1), aminoglycoside resistance genes (strA, strB, aadA, aphA), sulfonamide resistance genes (sul1, sul2, sul3), tetracycline resistance genes (tetA, tetB, tet34), trimethoprim resistance genes (dfrA1, dfrA17, dfr14), quinolone resistance genes (qnrB1), and others.
Antimicrobial Susceptibility and Resistance Mechanisms in Mannheimia haemolytica Isolates from Sheep at Slaughter.
The study identified the presence of tetracycline resistance gene tetH, aminoglycoside resistance gene strA, and sulfonamide resistance gene sul2 in M. haemolytica isolates. These genes were often found in plasmid sequences but did not consistently lead to resistance phenotypes.
ARGs Detection in Listeria Monocytogenes Strains Isolated from the Atlantic Salmon (Salmo salar) Food Industry: A Retrospective Study.
The study identified various AMR genes in L. monocytogenes strains from Atlantic salmon, including tetracycline resistance genes (tetC, tetD, tetK, tetL, tetS), aminoglycoside resistance genes (aadA, strA, aacC2, aphA1, aphA2), macrolide resistance genes (cmlA1, catI, catII), and oxazolidinone resistance genes (cfr, optrA, poxtA).
Evaluation of Enterotoxins and Antimicrobial Resistance in Microorganisms Isolated from Raw Sheep Milk and Cheese: Ensuring the Microbiological Safety of These Products in Southern Brazil.
The study identified several antimicrobial resistance genes, including tetM, ermB, strA, tetL, sul1, sul2, and AAC(6)', in Staphylococcus spp. isolated from raw sheep milk and cheese in southern Brazil. These genes conferred resistance to various antibiotics, highlighting the prevalence of antimicrobial resistance in these microorganisms.
A national study confirms that Escherichia coli from Australian commercial layer hens remain susceptible to critically important antimicrobials.
The study found that Escherichia coli from Australian commercial layer hens show low rates of antimicrobial resistance, with most isolates susceptible to all tested antimicrobials. Resistance was observed for several antibiotics, including tetracycline, ampicillin, and ciprofloxacin, but no resistance to critical antimicrobials like colistin. Whole genome sequencing identified various AMR genes such as aadA1, dfrA1, strA, strB, sul1, sul2, tet(A), lnu(C), blaTEM-1B, and qnrS1.
From Farm to Fork: Persistence of Clinically Relevant Multidrug-Resistant and Copper-Tolerant Klebsiella pneumoniae Long after Colistin Withdrawal in Poultry Production.
The study identified silA and pcoD genes associated with copper tolerance in Klebsiella pneumoniae isolates from poultry, and numerous chromosomal mutations linked to colistin resistance.
On the use of antibiotics to control plant pathogenic bacteria: a genetic and genomic perspective.
The study identifies several AMR genes and mutations associated with streptomycin, kasugamycin, gentamicin, and oxytetracycline resistance in plant pathogenic bacteria, highlighting the role of Tn 5393 and other mobile genetic elements in the dissemination of these resistance traits.
On the use of antibiotics to control plant pathogenic bacteria: a genetic and genomic perspective.
The study identifies several AMR genes and mutations associated with streptomycin, kasugamycin, gentamicin, and oxytetracycline resistance in plant pathogenic bacteria, highlighting the role of Tn 5393 and other mobile genetic elements in the dissemination of these resistance traits.
Investigation of multidrug-resistant plasmids from carbapenemase-producing Klebsiella pneumoniae clinical isolates from Pakistan.
The study identified 34 antimicrobial resistance genes (ARGs) in multidrug-resistant (MDR) plasmids from carbapenemase-producing Klebsiella pneumoniae clinical isolates in Pakistan, including bla NDM-1, bla OXA-48, and various beta-lactamases, aminoglycoside resistance genes, and others.
A survey of frequency of virulence and aminoglycoside antibiotic-resistant genotypes and phenotypes in Escherichia coli in broilers in Khartoum State, Sudan.
The study identified the presence of aminoglycoside-modifying enzyme genes strA and strB in Escherichia coli isolates from broilers in Khartoum State, Sudan, with high prevalence rates.
Incidence and Genomic Background of Antibiotic Resistance in Food-Borne and Clinical Isolates of Salmonella enterica Serovar Derby from Spain.
The study identified several AMR genes, including aadA2, sul1, tet(A), tet(B), tet(C), blaTEM-1, and fosA7.3, in Salmonella enterica serovar Derby isolates from Spain. These genes were associated with resistance to streptomycin, sulfonamides, tetracycline, ampicillin, and fosfomycin. Additionally, a point mutation in the gyrA gene was linked to nalidixic acid resistance.
The impact of applying various de novo assembly and correction tools on the identification of genome characterization, drug resistance, and virulence factors of clinical isolates using ONT sequencing.
The study evaluates the impact of various de novo assembly and read correction tools on the identification of antimicrobial resistance (AMR) genes, plasmids, and virulence factors in clinical Escherichia coli isolates using Oxford Nanopore sequencing. It highlights the effectiveness of Flye and Canu in detecting AMR genes and the importance of read correction tools like Medaka and Racon in improving assembly quality and AMR gene detection.
Molecular characterization of multidrug resistant Acinetobacter baumannii clinical isolates from Alexandria, Egypt.
The study identified various AMR genes in multidrug-resistant Acinetobacter baumannii isolates from Alexandria, Egypt, including bla OXA-51-like variants, bla OXA-23, bla NDM-1, bla PER-7, bla GES-like, and others, highlighting the widespread resistance to beta-lactams, aminoglycosides, tetracyclines, and other antibiotics.
Antimicrobial resistance heterogeneity among multidrug-resistant Gram-negative pathogens: Phenotypic, genotypic, and proteomic analysis.
The study identified various AMR genes in multidrug-resistant Gram-negative pathogens, highlighting the prevalence of bla CTX-M-15, bla CMY-42, bla NDM-5, aadA, bla TEM-1B, bla OXA-232, bla NDM-1, rmtB, rmtC, bla VEB, bla VIM-2, aph(3'), strA/B, bla OXA-23, aph (3′), catB, dfrB, bla VIM-2, fosA, oqxA, oqxB, bla OXA-23, bla CARB, bla OXA-91, bla OXA-51, bla PAO, bla SHV, aph (3′)-Ib, aph (6)-Id, mphE, msrE, ermB, mphA, aadA, rmtB, qnrB, dfrA, sul1, sul2, and fosA7.
Genomic traits of multidrug resistant enterotoxigenic Escherichia coli isolates from diarrheic pigs.
The study identified 53 resistance genes and 13 categories of 195 virulence factors in multidrug-resistant ETEC isolates from diarrheic pigs, including tet(A), floR, aph(3')-Ia, aadA2, bleO, sul3, dfrA12, QnrS1, and tet(X4).
Isolation and characterization of multidrug resistant Gallibacterium anatis biovar haemolytica strains from Polish geese and hens.
The study identified 25 different antimicrobial resistance genes in multidrug-resistant Gallibacterium anatis biovar haemolytica strains from Polish geese and hens, including tetB, blaTEM-1, blaROB-1, floR, sul2, sul3, dfrK, aadA1, aadA2, aph(3)-la, aph(3)-lb, aph(6)-ld, sat2, dfrA14, dfrA32, merC, merP, merR, merT, qacL, and cmlA1.
Occurrence of Acinetobacter baumannii genomic resistance islands (AbGRIs) in Acinetobacter baumannii strains belonging to global clone 2 obtained from COVID-19 patients.
The study identified several AMR genes within AbGRIs in GC2 A. baumannii isolates from COVID-19 patients, including strA, strB, tetA(B), tetR(B), sul2, oxa23, aacC1, aadA1, blaTEM, armA, aacA4, aphA1b, and sul1, which confer resistance to various antibiotics such as aminoglycosides, tetracyclines, sulfonamides, carbapenems, and beta-lactams.
Co-localization of clinically relevant antibiotic- and heavy metal resistance genes on plasmids in Klebsiella pneumoniae from marine bivalves.
The study identifies multiple antibiotic resistance genes (ARGs) and heavy metal resistance genes (HMRGs) co-localized on plasmids in Klebsiella pneumoniae isolated from marine bivalves, highlighting the potential for co-selection of these genes in the marine environment.
Clonal expansion and rapid characterization of Klebsiella pneumoniae ST1788, an otherwise uncommon strain spreading in Wales, UK.
The study identified several AMR genes in Klebsiella pneumoniae ST1788, including blaSHV-232, blaCTX-M-15, blaCTX-M-266, blaOXA-1, blaTEM-1, aac(3')-lla, aac(6')-lb-cr, strA, strB, qnrB1, dfrA14, sul2, and blaOXA-48. These genes confer resistance to various antibiotics such as beta-lactams, aminoglycosides, fluoroquinolones, trimethoprim, sulfamethoxazole, and carbapenems.
Phylogenetic lineages and antimicrobial resistance determinants of clinical Klebsiella oxytoca spanning local to global scales.
The study identified 10 variants of the intrinsic beta-lactamase gene blaOXY-2 in clinical Klebsiella oxytoca isolates, which confer resistance to penicillins. Additionally, two novel blaOXY-2 variants (blaOXY-2-35 and blaOXY-2-36) were discovered.
First Isolation and Identification of Aeromonas veronii in a Captive Giant Panda (Ailuropoda melanoleuca).
The study identifies 31 antibiotic resistance genes in Aeromonas veronii strain VGP, including aac, tetA-02, tnpA-05, aacC, and aadA2-02, which confer resistance to various antibiotics such as aminoglycosides, tetracycline, and others. The strain was found to be resistant to six antibiotics: penicillin, ampicillin, oxacillin, amoxicillin, imipenem, and vancomycin.
Conjugative Plasmid pPPUT-Tik1-1 from a Permafrost Pseudomonas putida Strain and Its Present-Day Counterparts Inhabiting Environments and Clinics.
The study characterizes the conjugative plasmid pPPUT-Tik1-1 from a permafrost Pseudomonas putida strain and identifies antibiotic resistance genes such as strA, merA, and blaVIM-2, along with mercury resistance determinants.
Genomic characterization of colistin-resistant Klebsiella pneumoniae isolated from intensive care unit patients in Egypt.
The study identifies mcr-1.1 as a plasmid-mediated colistin resistance gene and characterizes several chromosomal mutations in mgrB, arnT, pmrA, pmrB, pmrC, phoQ, and arnB that contribute to colistin resistance in K. pneumoniae isolates from Egypt.
Antibiotic Resistance Mediated by Escherichia coli in Kuwait Marine Environment as Revealed through Genomic Analysis.
The study identified various antibiotic resistance genes in Escherichia coli isolates from Kuwait's marine environment, including beta-lactamases, aminoglycoside-modifying enzymes, fluoroquinolone resistance genes, sulfonamide resistance genes, tetracycline resistance genes, and macrolide resistance genes. Additionally, the MFS-type drug efflux gene mdfA was commonly found in E. coli isolates.
Isolation and Characterization of the Acadevirus Members BigMira and MidiMira Infecting a Highly Pathogenic Proteus mirabilis Strain.
The study identifies multiple antibiotic resistance genes in the highly pathogenic Proteus mirabilis strain MCS, highlighting its multidrug-resistant profile. Key genes include tetA, aac(6')-Iq, aac(6')-Ib', aadA, dfrA1, blaOXA-9, blaCTX-M-2, vat, catA2, sul1, qacEdeltal, tetQ, blaTEM-135, aadA2, aph(3')-Ia, aph(6)-Id, aph(3'')-lb, and sulI.
Polymorphism and mutational diversity of virulence (vcgCPI/vcgCPE) and resistance determinants (aac(3)-IIa, (aacC2, strA, Sul 1, and 11) among human pathogenic Vibrio species recovered from surface waters in South-Western districts of Uganda.
The study identified various nucleotide variations in virulence determinants of V. vulnificus (vcgCPI) and resistance genes (strA, aadA, aac(3)-IIa, aacC2, sul1, and sul11) among Vibrio isolates.
Uncovering the hidden threat: The widespread presence of chromosome-borne accessory genetic elements and novel antibiotic resistance genetic environments in Aeromonas.
The study identifies novel antibiotic resistance genes, including blaVEB-1, tetA(E), and mcr-3.15, in clinical isolates of Aeromonas, highlighting the presence of chromosome-borne accessory genetic elements and new resistance mechanisms.
Comparative Genomic Analysis Reveals the Emergence of ST-231 and ST-395 Klebsiella pneumoniae Strains Associated with the High Transmissibility of bla(KPC) Plasmids.
The study identifies multiple AMR genes, including blaOXA-232, blaCTX-M-15, dfrA14, aac(6')-Ib-cr, and others, in K. pneumoniae isolates, highlighting the role of integrons and plasmids in the dissemination of resistance.
Characterization of Salmonella enterica serovar Isangi from South Africa, 2020-2021.
The study identified multiple AMR genes in Salmonella Isangi isolates, including ESBL genes like bla CTX-M-15, bla CTX-M-22, bla CTX-M-3, and others, as well as plasmid-mediated AmpC genes like bla DHA-1 and bla NDM-1. Resistance to multiple antibiotics was observed, highlighting the need for continued monitoring of AMR in this serovar.
Dynamics of antimicrobial resistance and virulence of staphylococcal species isolated from foods traded in the Cape Coast metropolitan and Elmina municipality of Ghana.
The study identified multiple antimicrobial resistance genes in staphylococcal isolates from food samples, including genes conferring resistance to tetracycline, gentamicin, methicillin, erythromycin, and vancomycin. High prevalence of multidrug resistance was observed, highlighting the potential health risks associated with food-borne staphylococci.
Genomic characterization of tigecycline-resistant Escherichia coli and Klebsiella pneumoniae isolates from hospital sewage.
The study identifies tet(X4) and tmexCD1-toprJ1 as key genes contributing to tigecycline resistance in E. coli and K. pneumoniae isolates from hospital sewage, highlighting the role of plasmid-mediated resistance and efflux pump overexpression.
Genetic characterization of a multidrug-resistant Salmonella enterica serovar Agona isolated from a dietary supplement in Germany.
The study identifies 23 antibiotic resistance genes (ARGs) in a multidrug-resistant Salmonella enterica serovar Agona isolate from a dietary supplement in Germany, conferring resistance to 12 different antibiotic classes. Key genes include blaSHV-12, aac(3)-Iig, aac(6')-Iic, aadA2, aph(3')-Ia, aph(3'')-Ib, aph(6)-Id, dfrA19, qacEΔ1, ere(A), sul1, sul2, tet(D), mcr-9.1, catA2, arr, qnrS1, blaTEM-1, aac(3)-IIe, and floR.
Multiple host colonization and differential expansion of multidrug-resistant ST25-Acinetobacter baumannii clades.
The study identifies multiple AMR genes, including bla OXA-23, bla NDM-1, armA, sul2, strA, strB, tet(B), aac(6')-Ian, and aac(3)-IIa, in multidrug-resistant ST25 Acinetobacter baumannii clades, highlighting their role in resistance to various antibiotics.
Genomic analysis of Shigella isolates from Lebanon reveals marked genetic diversity and antimicrobial resistance.
The study identified multiple antimicrobial resistance genes and mutations in Shigella isolates from Lebanon, including bla CTX-M-15 and bla CTX-M-3 for extended-spectrum beta-lactamase resistance, and gyrA mutations for quinolone resistance.
Characterization of Riemerella anatipestifer Strains Isolated from Various Poultry Species in Poland.
The study identified several AMR genes in R. anatipestifer isolates, including aminoglycoside resistance genes (aph(3′)-VII, aac(3′)-IV, aadA, strA/strB), tetracycline resistance genes (tet(A), tet(B), tet(X)), erythromycin resistance gene (ermF), chloramphenicol resistance gene (cmlA), beta-lactam resistance gene (bla TEM), and sulfonamide resistance gene (sulI).
Serovars, Virulence and Antimicrobial Resistance Genes of Non-Typhoidal Salmonella Strains from Dairy Systems in Mexico.
Tracing the Evolutionary Pathways of Serogroup O78 Avian Pathogenic Escherichia coli.
The study characterizes the AMR genes and mutations in O78 APEC strains, highlighting the presence of resistance genes such as blaTEM, blaSHV, blaCTX-M, ampC, tetB, tetA, sul1, sul2, dfrA1, aadA, aac(3)II, strA/strB, and floR, indicating multidrug resistance in these strains.
Tracing the Evolutionary Pathways of Serogroup O78 Avian Pathogenic Escherichia coli.
The study characterizes the AMR genes and mutations in O78 APEC strains, highlighting the presence of resistance genes such as blaTEM, blaSHV, blaCTX-M, ampC, tetB, tetA, sul1, sul2, dfrA1, aadA, aac(3)II, strA/strB, and floR, indicating multidrug resistance in these strains.
Genomic Insights into the Adaptation and Antibiotic Resistance Mechanisms of Williamsia chitiniclastica
The study identifies several AMR genes in Wohlfahrtiimonas chitiniclastica, including macA, macB, tehB, tet(H), tet(B), ant(2″)-Ia, aac(6′)-Ib, ant(3″)-Ib, bla VEB-1, bla OXA-1, aph(3′)-Ib, sul2, strA, and dfrA1, which confer resistance to various antibiotics such as macrolides, tetracycline, aminoglycosides, beta-lactams, sulfonamides, and trimethoprim.
Genomic and functional insights into antibiotic resistance genes floR and strA linked with the SXT element of Vibrio cholerae non-O1/non-O139.
The study identifies and characterizes the floR and strAB genes linked with the SXT element in Vibrio cholerae non-O1/non-O139, demonstrating their roles in conferring resistance to chloramphenicol and streptomycin, respectively.
Determination of antibiotic resistance patterns and genotypes of Escherichia coli isolated from wild birds.
The study identified several AMR genes in E. coli isolates from wild birds, including tet(A), tet(B), strA/strB, aphA1, sul1, sul2, and sul3, which confer resistance to tetracycline, streptomycin, kanamycin, and sulfonamides.
Occurrence, genetic diversity and resistance profiles of Salmonella enterica from Brazilian sausages collected at production facilities.
The study identified Salmonella enterica isolates carrying resistance genes tet(B), strA, strB, and sul2, which confer resistance to tetracycline, streptomycin, and sulfonamide. These isolates were found in sausages from Southern Brazil, highlighting the public health concern of antimicrobial resistance in food products.
Emergence of multidrug resistant, ctx negative seventh pandemic Vibrio cholerae O1 El Tor sequence type (ST) 69 in coastal water of Kerala, India.
The study identifies multidrug-resistant Vibrio cholerae O1 El Tor sequence type 69 in coastal waters of Kerala, India, which lacks the ctx gene but contains several antimicrobial resistance genes including sul2, dfrA1, strA, strB, parC, parE, catB9, and floR.
Plasmid content of carbapenem resistant Acinetobacter baumannii isolates belonging to five International Clones collected from hospitals of Alexandria, Egypt.
The study characterizes various AMR genes in carbapenem-resistant Acinetobacter baumannii isolates, including blaOXA-23, blaPER-7, blaGES-11, blaGES-35, aph(3')-VI, aac(6')-Ib, sul1, sul2, mph(E), msr(E), armA, strA, strB, cmlA5, arr-2, ant(3'')-II, aadA1-pm, tet(B), tet(39), qacEΔ1, and dfrA7.
Genomic Characterization of Two NDM-5-Producing Isolates of Klebsiella pneumoniae ST11 from a Single Patient.
The study identified two NDM-5-producing K. pneumoniae ST11 isolates from a single patient, highlighting the presence of multiple acquired antimicrobial resistance genes, including blaNDM-5, blaCTX-M-15, and rmtB, along with other resistance determinants.
Dynamics of Antimicrobial Resistance Carriage in Koalas (Phascolarctos Cinereus) and Pteropid Bats (Pteropus Poliocephalus) Before, During and After Wildfires.
The study identified various antimicrobial resistance genes, including class 1 integrons and bla TEM genes, in koalas and Pteropid bats before, during, and after wildfires. The presence of these genes was influenced by factors such as fire-impact, captivity, and antibiotic usage.
Phenotypic and genetic characterization of antimicrobial resistance in Salmonella enterica serovar Choleraesuis isolates from humans and animals in Spain from 2006 to 2021.
The study identified various antimicrobial resistance genes and mutations in Salmonella enterica serovar Choleraesuis isolates from humans and animals in Spain, highlighting the presence of multidrug-resistant strains and the role of plasmids in the dissemination of resistance mechanisms.
Genomic Surveillance Uncovers a 10-Year Persistence of an OXA-24/40 Acinetobacter baumannii Clone in a Tertiary Hospital in Northern Spain.
The study identifies the persistence of an OXA-24/40 Acinetobacter baumannii clone over 10 years in a Spanish hospital, highlighting the role of the bla OXA-24/40 gene and a novel variant, bla OXA-1040, in carbapenem resistance. It also characterizes other resistance genes such as aad A1, aph (3')-VIa-like, str A, str B, sul1, sul2, and tet(B)-like, contributing to multidrug resistance.
In-depth characterization of multidrug-resistant NDM-1 and KPC-3 co-producing Klebsiella pneumoniae bloodstream isolates from Italian hospital patients.
The study characterized multidrug-resistant NDM-1 and KPC-3 co-producing Klebsiella pneumoniae bloodstream isolates, identifying several AMR genes and mutations associated with resistance to various antibiotics.
Genomic insights and antimicrobial resistance profiles of CRKP and non-CRKP isolates in a Beijing geriatric medical center: emphasizing the bla(KPC-2) carrying high-risk clones and their spread.
The study identifies blaKPC-2 as a key gene in carbapenem resistance among CRKP isolates, along with other resistance genes such as rmtB, APH(3')-Ia, and QnrB4. It also highlights the prevalence of ST11-KL47-OL101 clones and the role of plasmid pKpnR03_2 in the spread of resistance.
Occurrence and molecular characteristics of antimicrobial resistance, virulence factors, and extended-spectrum β-lactamase (ESBL) producing Salmonella enterica and Escherichia coli isolated from the retail produce commodities in Bangkok, Thailand.
The study identified several AMR genes and mutations in Salmonella enterica and Escherichia coli isolated from retail produce in Bangkok, Thailand. Key findings include the presence of bla TEM, qnrS, tetA, tetB, strA, and strB genes, as well as gyrA and parC mutations associated with ciprofloxacin resistance.
Antimicrobial Resistance and Molecular Characterization of Salmonella Rissen Isolated in China During 2008-2019.
The study identified multiple AMR genes in Salmonella Rissen isolates from China, including blaTEM, sul2, sul3, tetA, strA, strB, aadA, intl1VR(cx), and qacED1, which contribute to resistance against various antibiotics such as ampicillin, trimethoprim-sulfamethoxazole, tetracycline, and streptomycin.
Outbreak of NDM-5-producing Klebsiella pneumoniae ST307: an emerging high-risk antimicrobial resistance clone in Shanghai, China.
The study reports an outbreak of NDM-5-producing Klebsiella pneumoniae ST307 in Shanghai, China, highlighting the presence of multiple resistance genes including bla NDM-5, bla CTX-M-15, and bla DHA-1, which confer resistance to carbapenems, cephalosporins, and other antibiotics.
Characterization of the diversity of type IV secretion system-encoding plasmids in Acinetobacter.
The study characterizes the diversity of T4SS-encoding plasmids in Acinetobacter, identifying various antibiotic resistance genes such as blaOXA-23, blaOXA-82, blaGES-11, aph(3')-VIa, aadA2, sul1, dfrA7, cmlA1, and qacEΔ1, highlighting their role in multidrug resistance.
Wounds of Companion Animals as a Habitat of Antibiotic-Resistant Bacteria That Are Potentially Harmful to Humans-Phenotypic, Proteomic and Molecular Detection.
The study identified several antibiotic resistance genes, including strA (streptomycin resistance), sul3 (sulfonamide resistance), and blaTEM (extended-spectrum beta-lactamase), in bacterial isolates from companion animal wounds. These genes were detected using PCR and were associated with resistance to specific antibiotics.
Genomic analysis of Salmonella isolated from canal water in Bangkok, Thailand.
The study identified 35 AMR genes and 30 chromosomal-mediated gene mutations in Salmonella strains from Bangkok canal water, highlighting the presence of multidrug-resistant strains with resistance to various antimicrobial classes.
Comparison of genotypic and phenotypic antimicrobial resistance profiles of Salmonella enterica isolates from poultry diagnostic specimens.
The study identified 31 AMR genes in 97 Salmonella enterica isolates from poultry, including aac(3)-IId, aac(3)-IVa, aac(3)-VIa, aac(6′)-Ib4, ant(2′′)-Ia, grdA, aph(3′)-Ia, aph(3′)-IIa, aadA1, aadA2, aadA7, aadA13, aph(3′)-Ib, aph(6)-Ic, aph(6)-Id, aph(4)-Ia, blaCMY-2, blaCTX-M-1, blaHER-3, blaTEM-1, floR, tetA, tetB, tetC, dfrA12, sul1, sul2, fosA7, qnrB19, ble, and mcr-9.
Cryptic environmental conjugative plasmid recruits a novel hybrid transposon resulting in a new plasmid with higher dispersion potential.
The study identifies a novel hybrid transposon Tn7714 carrying multiple antibiotic resistance genes (ARGs) that was transferred from an IncF plasmid to a cryptic IncX plasmid, resulting in a new multidrug-resistant conjugative plasmid with significantly higher conjugation efficiency.
Unveiling the genetic architecture and transmission dynamics of a novel multidrug-resistant plasmid harboring bla(NDM-5) in E. Coli ST167: implications for antibiotic resistance management.
The study identifies a novel multidrug-resistant plasmid pNDM-5-0083 carrying bla NDM-5, bla TEM-1B, aadA2, rmtB, dfrA12, and sul1, which contributes to resistance against multiple antibiotics in E. coli ST167.
Detection of Salmonella Pathogenicity Islands and Antimicrobial-Resistant Genes in Salmonella enterica Serovars Enteritidis and Typhimurium Isolated from Broiler Chickens.
The study identified several antimicrobial-resistant genes in Salmonella enterica serovars Enteritidis and Typhimurium isolated from broiler chickens, including tet(K), tet(O), tet(A), mcr-1, mcr-4, strA, strB, aadA, aadE, sulI, ampC, TEM, CTX-M, and OXA. These genes conferred resistance to tetracycline, colistin, aminoglycosides, sulfonamides, and beta-lactam antibiotics.
Molecular basis of the persistence of chloramphenicol resistance among Escherichia coli and Salmonella spp. from pigs, pork and humans in Thailand.
The study identifies catA and cmlA as the primary genes responsible for chloramphenicol resistance in E. coli and Salmonella isolates from Thailand, highlighting their persistence through co-selection and horizontal gene transfer.
Genomic analysis of multidrug-resistant Escherichia coli from Urban Environmental water sources in Accra, Ghana, Provides Insights into public health implications.
The study identified several AMR genes in multidrug-resistant E. coli isolates from urban environmental water sources in Accra, Ghana, highlighting the presence of beta-lactamases (blaTEM-1B, blaCTX-M-15, blaTEM-1C, blaDHA-1, blaOXA-1, blaOXA-181), sulfonamide resistance genes (sul2, sul1), aminoglycoside resistance genes (aph(6)-Id, aadA2, mph(A)), quinolone resistance gene (qnrS1), tetracycline resistance gene (tet(B)), chloramphenicol resistance gene (catA1), dihydrofolate reductase (dfrA14), and others.
Genomic characterisation of Escherichia coli isolated from poultry at retail through Sink Surveillance in Dhaka, Bangladesh reveals high levels of multi-drug resistance.
The study identified multiple AMR genes in E. coli isolates from poultry in Bangladesh, including genes conferring resistance to various antibiotics such as tetracycline, ciprofloxacin, azithromycin, colistin, and others. High levels of multidrug resistance were observed, with specific genes like mcr1.1, bla CTX-M-65, and tet(A) playing significant roles.
Mobile genetic elements define the non-random structure of the Salmonella enterica serovar Typhi pangenome.
The study identifies multiple AMR genes, including blaTEM-1B, qnrS1, sul2, tet(A), aph(3'')-Ib, aph(6)-Id, dfrA14, blaCTX-M-15, blaCTX-M-88, catA1, qacE, sul1, and tet(B), which are associated with multidrug-resistant and extensively drug-resistant Salmonella enterica serovar Typhi strains.
Host species shapes genotype, antimicrobial resistance, and virulence profiles of enterotoxigenic Escherichia coli (ETEC) from livestock in the United States.
The study identifies distinct antimicrobial resistance (AMR) gene profiles in bovine and swine enterotoxigenic Escherichia coli (ETEC) isolates, highlighting differences in the prevalence of specific AMR genes and plasmid replicons between the two host species.
Genomic Evaluation of Multidrug-Resistant Extended-Spectrum β-Lactamase (ESBL)-Producing Escherichia coli from Irrigation Water and Fresh Produce in South Africa: A Cross-Sectional Analysis.
The study identified several AMR genes in multidrug-resistant ESBL-producing E. coli isolates from irrigation water and fresh produce in South Africa, including bla CTX-M-1, bla CTX-M-14, bla CTX-M-15, aph(6)-Id, ant(3″)-Ia, aadA2, aph(3″)-Ib, sul2, sul3, dfrA1, fosA3, cmlA1, and floR.
Antimicrobial resistance profiles and genome characteristics of Klebsiella isolated from the faeces of neonates in the neonatal intensive care unit.
The study identified multiple antimicrobial resistance genes in Klebsiella isolates from neonates in the NICU, including bla NDM-1, bla CTX-M-15, bla SHV-67, aac(6')-Ib-cr, aadA16, aph(3'')-Ib, and others. These genes confer resistance to various antibiotics such as carbapenems, cephalosporins, aminoglycosides, and fluoroquinolones. Additionally, the study found a multidrug-resistant Klebsiella pneumoniae strain carrying several resistance genes and plasmids.
Genomic Characteristics of a Carbapenem-Resistant Klebsiella pneumoniae Co-Carrying bla (NDM-5) and bla (KPC-2) Capsular Type KL25 Recovered from a County Level Hospital in China.
The study reports the genomic characteristics of a multidrug-resistant ST11 Klebsiella pneumoniae isolate SM117 with capsular serotype KL25, co-carrying bla NDM-5, two copies of bla KPC-2, and multiple plasmid-borne virulence genes. The isolate shows resistance to all antibiotics except polymyxin.
Prophage-encoded antibiotic resistance genes are enriched in human-impacted environments.
Human-impacted environments show a significant enrichment of prophage-encoded antibiotic resistance genes (pARGs), which are more prevalent and widely distributed compared to those from low-antibiotic exposure habitats. Experimental validation confirms that some pARGs confer resistance to antibiotics in heterologous hosts.
Genomic Characterization of Extended-Spectrum β-Lactamase-Producing and Third-Generation Cephalosporin-Resistant Escherichia coli Isolated from Stools of Primary Healthcare Patients in Ethiopia.
The study identified multiple antimicrobial resistance genes in E. coli isolates, including bla CTX-M-15, bla TEM-1B, tet(A), qnrS1, and others, highlighting the prevalence of multidrug resistance in the region.
Investigation on the mechanisms of carbapenem resistance among the non-carbapenemase-producing carbapenem-resistant Klebsiella pneumoniae.
The study identified non-carbapenemase β-lactamase genes and chromosomal mutations, including missense mutation or loss of ompK36 porin and frameshift missense mutation in efflux pump systems, as potential mechanisms of carbapenem resistance in NC-CRKP.
Genomic analysis of Enterobacteriaceae from colorectal cancer patients at a tertiary hospital in Ghana: a case-control study.
The study identified various antimicrobial resistance genes in Enterobacteriaceae isolated from colorectal cancer patients and healthy controls, including ampC2, ampH, strA, strB, mphA, sul1, sul2, tetA, tetR, and dfrA14.
Genomics unveils country-to-country transmission between animal hospitals of a multidrug-resistant and sequence type 2 Acinetobacter baumannii clone.
The study identifies several AMR genes and mutations in a multidrug-resistant Acinetobacter baumannii clone, including blaCARB-16, tetA, gyrA, parC, IS26, ABGRI1, ABGRI2, aphA1, strA, and strB, which contribute to resistance against various antibiotics.
Analyzing Antibiotic Resistance in Bacteria from Wastewater in Pakistan Using Whole-Genome Sequencing.
The study identifies several AMR genes and mutations in wastewater isolates from Pakistan, highlighting the presence of carbapenemases like blaNDM-5 and blaOXA-1, as well as quinolone resistance determinants such as gyrA and parC mutations. These findings emphasize the role of wastewater as a reservoir for clinically relevant AMR genes.
Genomic Characterization of 16S rRNA Methyltransferase-Producing Enterobacterales Reveals the Emergence of Klebsiella pneumoniae ST6260 Harboring rmtF, rmtB, bla(NDM-5), bla(OXA-232) and bla(SFO-1) Genes in a Cancer Hospital in Bulgaria.
The study identifies the emergence of Klebsiella pneumoniae ST6260 harboring multiple AMR genes, including rmtF, rmtB, bla(NDM-5), bla(OXA-232), and bla(SFO-1), highlighting the complexity of resistance mechanisms in Enterobacterales.
Molecular Characterization of Multidrug-Resistant Escherichia coli from Fecal Samples of Wild Animals.
The study identified multiple AMR genes in E. coli isolates from wild animals, including beta-lactamases (bla TEM-1B, bla CTX-M-65, bla CTX-M-55, bla EC-1982), aminoglycoside resistance genes (aac(3)-IIa, aadA2, aadA5, ant(3")-Ia, aph(3")-Ib, aph(3′)-Ia, aph(6)-Id), tetracycline resistance genes (tetB, tetA), trimethoprim resistance genes (dfrA17, dfrA1, dfrA5, dfrA12), sulfonamide resistance genes (sul1, sul2, sul3), macrolide/lincosamide/streptogramin resistance genes (mphB, lnuF, ermC, mefC), quinolone resistance genes (qnrB19, qnrB5, qnrS1, qnrS2), and others. Additionally, point mutations in gyrA, parC, and parE were associated with fluoroquinolone resistance.
Natural compound-induced downregulation of antimicrobial resistance and biofilm-linked genes in wastewater Aeromonas species.
The study identifies aadA1, aadA2, and sul1 as antimicrobial resistance genes in wastewater Aeromonas species, which are downregulated by natural compounds.
Combatting extensively drug-resistant Salmonella: a global perspective on outbreaks, impacts, and control strategies.
The paper discusses the emergence and global spread of extensively drug-resistant (XDR) Salmonella, highlighting the resistance mechanisms involving genes such as blaCTX-M-15, floR, cat1, cat2, strA, strB, aacC(3), aadA, ant(3")-Ia, aph(3)-IIa, tet(A), tet(B), tet(D), tet(G), tet(H), dfrA10, dhfrXII, sul1, sul2, sul3, mphA, and ermB.
Genomic characterisation of an extended-spectrum β-Lactamase-producing Klebsiella pneumoniae isolate assigned to a novel sequence type (6914).
The study reports the genomic characterization of an extended-spectrum β-Lactamase-producing Klebsiella pneumoniae isolate, Cow102, which exhibits multidrug resistance. It identifies several resistance genes, including blaSHV-1, blaSHV-11, blaSHV-13, blaSHV-26, blaSHV-70, blaSHV-78, blaSHV-98, blaSHV-145, blaTEM-1B, aadA2, catA2, catII, dfrA16, fosA, oqxA, oqxB, sul1, sul2, and tet(D).
Genomic epidemiology and phenotypic characterisation of Salmonella enterica serovar Panama in Victoria, Australia.
The study identifies the first plasmid-mediated colistin-resistant Salmonella enterica serovar Panama in Australia, highlighting the emergence of multidrug resistance in this invasive non-typhoidal Salmonella serovar.
First Detection of High-Level Aminoglycoside-Resistant Klebsiella pneumoniae and Enterobacter cloacae Isolates Due to 16S rRNA Methyltransferases with and Without bla(NDM) in Uruguay.
The study identifies the first detection of high-level aminoglycoside-resistant Klebsiella pneumoniae and Enterobacter cloacae isolates in Uruguay, carrying 16S rRNA methyltransferases (rmtB, rmtC, rmtD) along with carbapenemase genes (bla NDM-5, bla NDM-1).
Evaluating the health risk of probiotic supplements from the perspective of antimicrobial resistance.
Probiotics from health supplements were found to harbor ARGs conferring resistance to tetracycline, macrolide, aminoglycoside, and glycopeptide antibiotics. Specifically, aadA and erm(B)-1 were detected in transconjugants after co-incubation with streptomycin-adapted probiotics.
Emergence of mcr-8.1-bearing MDR-hypervirulent Klebsiella pneumoniae ST307.
The study identifies the colistin resistance gene mcr-8.1 in multidrug-resistant Klebsiella pneumoniae ST307 isolates from Armenia, highlighting the emergence of this gene in the region.
Investigation of integron gene cassettes in trimethoprim-sulfamethoxazole-resistant Acinetobacter baumannii isolates.
The study identified dfrA12 and aadA2 genes in class I integrons, and dfrA1 and sat2 genes in class II integrons in trimethoprim-sulfamethoxazole-resistant Acinetobacter baumannii isolates.
Genomic and metabolic characterization of Trueperella pyogenes isolated from domestic and wild animals.
The study identified multiple antimicrobial resistance (AMR) genes in Trueperella pyogenes, including tet(W/32/O), erm(X), vanG, sul1, and qacEdelta1, which confer resistance to tetracyclines, MLS B, glycopeptides, sulfonamides, and biocides, respectively. These genes were detected in various T. pyogenes isolates from different animal hosts and body sites, highlighting the genetic diversity and potential for AMR dissemination among different hosts.
Tracking Multidrug Resistance in Gram-Negative Bacteria in Alexandria, Egypt (2020-2023): An Integrated Analysis of Patient Data and Diagnostic Tools.
The study identified bla NDM-5 as the most prevalent carbapenemase gene in E. coli isolates from Alexandria, Egypt, along with other resistance genes such as bla OXA-48, bla VIM, bla CTX-M-15, aadA2, aac(6')-Ib, qnrS1, dfrA12, sul1, and sul2.
Phenotypic and Genomic Characterization of ESBL- and AmpC-β-Lactamase-Producing Enterobacterales Isolates from Imported Healthy Reptiles.
The study identified multiple ESBL and AmpC β-lactamase genes, including bla CTX-M-15, bla CTX-M-55, bla CTX-M-3, bla CTX-M-27, bla CTX-M-65, bla SHV-12, bla SHV-42, bla DHA-1, bla CMY-2, bla CMY-3, bla CMY-46, bla CMY-101, bla ACT-16, bla CMH-like, and bla MIR-9, along with other AMR genes such as mcr-1, qnrS1, aac(6')-Ib-cr5, and various tetracycline, aminoglycoside, sulfonamide, chloramphenicol, macrolide, lincosamide, and rifampicin resistance genes in Enterobacterales isolates from imported healthy reptiles.
Antibiotic Resistance in Mammalian Wild Game: A Meta-Analysis
The study presents a comprehensive meta-analysis of antibiotic resistance in bacteria isolated from mammalian wild game, highlighting the prevalence of various AMR genes and mutations across different bacterial species.
Prevalence and genomic insights of carbapenem resistant and ESBL producing Multidrug resistant Escherichia coli in urinary tract infections.
The study identified multiple AMR genes, including NDM-5, CTX-M-15, TEM-1, and others, in carbapenem-resistant and ESBL-producing multidrug-resistant E. coli isolates from urinary tract infections.
Phenotypic and genotypic characterization of antimicrobial resistance and virulence profiles of Salmonella enterica serotypes isolated from necropsied horses in Kentucky.
The study identified several AMR genes in Salmonella enterica isolates from necropsied horses, including beta-lactamase genes (blaTEM, blaCTX-M, blaSHV2, blaOXA-9), aminoglycoside resistance gene (aacA[3]), sulfonamide resistance gene (sul2), amphenicol resistance gene (floR), tetracycline resistance gene (tetB), streptomycin resistance gene (strA), macrolide resistance gene (ermB2), and quinolone resistance gene (qnrB2). These genes were associated with resistance to multiple antibiotics, highlighting the presence of multidrug-resistant Salmonella strains.
Phenotypic and genetic heterogeneity of Acinetobacter baumannii in the course of an animal chronic infection.
The study identified a conserved colistin resistance due to a pmrB mutation in Acinetobacter baumannii isolates during a 5-year urinary tract infection in an animal patient, despite the absence of antibiotic treatment.
Antimicrobial Resistance in Pasteurella multocida Isolates from Bovine Mastitis Can Be Associated with Multidrug-Resistance-Mediating Integrative and Conjugative Elements (ICEs).
Characterization of Klebsiella pneumoniae Isolates Resistant to Cefiderocol from Hospitals and Outpatient Settings in Croatia.
The study characterizes AMR genes in FDC-resistant K. pneumoniae isolates, identifying bla OXA-48, bla KPC, bla NDM, bla CTX-M, aac(6')-Ib, aadA1, aadA2, qnrB, shv, and tem as significant contributors to resistance.
Unveiling the silent threat: A comprehensive review of Riemerella anatipestifer - From pathogenesis to drug resistance.
This review highlights the pathogenesis, virulence factors, and antibiotic resistance genes of Riemerella anatipestifer, emphasizing its significance in poultry farming and the need for further research on its resistance mechanisms.
Drug resistance and genotyping studies of Salmonella Enteritidis isolated from broiler chickens in Iran.
The study identified several AMR genes in Salmonella Enteritidis isolates from broiler chickens in Iran, including bla TEM, tet A, tet B, sul 1, and str A/B, which conferred resistance to various antibiotics.
Carbapenem-Resistant, Virulence Plasmid-Harboring Klebsiella pneumoniae, United States.
The study identifies six pVir-CRKP isolates from the United States, highlighting their multidrug resistance and enhanced virulence traits. These isolates exhibit resistance to various antibiotics, including carbapenems, cephalosporins, fluoroquinolones, and aminoglycosides, due to the presence of specific AMR genes and mutations.
Carbapenem-Resistant, Virulence Plasmid-Harboring Klebsiella pneumoniae, United States.
The study identifies six pVir-CRKP isolates from the United States, highlighting their multidrug resistance and enhanced virulence traits. These isolates exhibit resistance to various antibiotics, including carbapenems, cephalosporins, fluoroquinolones, and aminoglycosides, due to the presence of specific AMR genes and mutations.
Impact of the Technical Snow Production Process on Bacterial Community Composition, Antibacterial Resistance Genes, and Antibiotic Input-A Dual Effect of the Inevitable.
The study identified several antibiotic resistance genes (ARGs) in water and snow samples from ski resorts, including blaTEM, blaCTX-M, mecA, ereA, ermB, strA, tetK, and sulIII. These genes were associated with resistance to beta-lactams, macrolides, aminoglycosides, tetracyclines, and sulfonamides. The presence of these ARGs highlights the potential environmental impact of technical snow production on antimicrobial resistance.
Strict relationship between phenotypic and plasmid-associated genotypic of multidrug-resistant Escherichia coli isolated from Taihe Black-Boned Silky Fowl farms.
The study identified multiple AMR genes in multidrug-resistant E. coli isolates from Taihe Black-Boned Silky Fowl farms, including blaTEM, blaOXA-10, tetA, tetR, floR, cmlA, qnrS, strA, strB, aadA, aac(3)-IId, sul, and dfrA. These genes were associated with resistance to beta-lactams, tetracyclines, chloramphenicol, fluoroquinolones, aminoglycosides, and sulfonamides.
Comprehensive genomic epidemiology and antimicrobial resistance profiles of clinical Klebsiella pneumoniae species complex isolates from a tertiary hospital in Wenzhou, China (2019-2021).
The study identified a variety of antimicrobial resistance genes in clinical Klebsiella pneumoniae species complex isolates, including bla KPC−2, bla CTX−M, bla SHV, aac(6')-Ib, aadA1, aadA2, aph(3')-Ia, oqxAB, qnrB19, qnrS1, tet(A), tet(D), sul1, sul2, sul3, cmlA1, floR, fosA, and fosA3. These genes confer resistance to multiple classes of antibiotics, highlighting the complexity of antimicrobial resistance in these isolates.
Comprehensive molecular epidemiology of Acinetobacter baumannii from diverse sources in Nigeria.
The study identified 168 AMR genes in 189 Nigerian A. baumannii isolates, including blaADC-79, blaOXA-23, aph(3")-Ib, and others, highlighting the widespread presence of multidrug resistance.
Genomic Characterization of NDM-1 Harboring Extensively-Drug Resistance Klebsiella pneumoniae Isolate From ICU-Admitted Patient With COVID-19.
The study identified multiple antimicrobial resistance genes in an extensively drug-resistant Klebsiella pneumoniae isolate, including bla NDM-1, armA, msrE, mphE, BRP, bla OXA-1, aadA2, dfrA12, qnrB1, bla CTX-M-15, and cat1, highlighting the complex resistance mechanisms in this isolate.
Intestinal and Extraintestinal Pathotypes of Escherichia coli Are Prevalent in Food Prepared and Marketed on the Streets from the Central Zone of Mexico and Exhibit a Differential Phenotype of Resistance Against Antibiotics.
The study identifies multiple antibiotic resistance genes in E. coli isolates from street-prepared food in Mexico, including strA, sul1, catA1, floR, qnrS, and tetA, which confer resistance to streptomycin, sulfonamides, chloramphenicol, quinolones, and tetracycline.
Genome-Based Molecular Diversity of Extended-Spectrum β-Lactamase-Producing Escherichia coli From Pigeons in China.
The study identifies multiple extended-spectrum β-lactamase (ESBL) genes, including bla CTX-M, bla TEM, bla OXA, bla LAP, and bla CMY, as well as other antibiotic resistance genes such as mcr-1, mcr-1.1, tet(X4), aadA1, aadA2, aph(6)-Id, aph(3")-Ib, aph(3')-Ia, aph(3')-IIa, aac(3)-IVa, aph(4)-Ia, tet(A), tet(M), sul2, sul3, dfrA14, qnrS1, arr-2, fosA3, cmlA5, floR, mph(A), and lnu(F) in ESBL-producing E. coli isolates from pigeons in China.
A decade of genomic and phenotypic adaptation of carbapenem-resistant Acinetobacter baumannii.
The study identifies various AMR genes and mutations in carbapenem-resistant Acinetobacter baumannii isolates, including blaOXA-23, blaOXA-51-like, and several aminoglycoside resistance genes, contributing to extensive drug resistance.
Antimicrobial Resistance in Nigeria: A Comprehensive Review of Environmental, Food, and Clinical Impacts
The study identifies several AMR genes, including bla CTX-M-15, floR, and various tetracycline and sulfonamide resistance genes, highlighting the spread of multidrug-resistant bacteria in Nigeria's environment, food supply chain, and clinical settings.
Antimicrobial Resistance in Nigeria: A Comprehensive Review of Environmental, Food, and Clinical Impacts
The study identifies several AMR genes, including bla CTX-M-15, floR, and various tetracycline and sulfonamide resistance genes, highlighting the spread of multidrug-resistant bacteria in Nigeria's environment, food supply chain, and clinical settings.
The pet café is a neglected site for transmission of antimicrobial-resistant Escherichia coli in urban life.
The study identifies multiple antimicrobial resistance genes (ARGs) in Escherichia coli isolates from pet cafés, highlighting the role of plasmids in the transmission of these genes. Key ARGs include tet(X4), sul2, sul3, strA, strB, dfrA14, qnrS1, qnrS2, oqxB, blaCTX-M-15, blaCTX-M-14, blaCTX-M-65, floR, and tet(A).
Genomic Insights of Antibiotic-Resistant Escherichia coli Isolated from Intensive Pig Farming in South Africa Using 'Farm-to-Fork' Approach.
The study identified multiple antibiotic resistance genes and mutations in E. coli isolates from intensive pig farming in South Africa, highlighting the spread of resistance across the pork production continuum.
Integrated genomic-epigenomic-transcriptomic analyses reveal adaptive mechanisms of colistin and carbapenem resistance in Klebsiella pneumoniae and Enterobacter isolates
The study identifies multiple AMR genes and mutations associated with colistin and carbapenem resistance in Klebsiella pneumoniae and Enterobacter isolates, including beta-lactamases, fosfomycin resistance genes, and efflux pumps. Mutations in ompK35 were found to contribute to carbapenem resistance.
Genomic insights into antibiotic-resistant non-typhoidal Salmonella isolates from outpatients in Minhang District in Shanghai.
The study identifies multiple antibiotic resistance genes and mutations in non-typhoidal Salmonella isolates from Minhang District, Shanghai, highlighting the prevalence of multidrug-resistant strains and the role of specific genetic elements in resistance mechanisms.
Retrospective analysis of antimicrobial resistance of Salmonella spp. isolated from livestock and its environment in Thailand.
The study identified several AMR genes in Salmonella isolates from livestock and their environment in Thailand, including aadA1, aadA2, aadB, aac(6')-Ia, blaTEM, tetA, tetB, catA, catB, cmlA, sulI, and dfrA1, which confer resistance to various antibiotics such as aminoglycosides, beta-lactams, tetracyclines, chloramphenicol, sulfamethoxazole, and trimethoprim.
Characterization of the Diversity in Host Range of an Extensively Drug-Resistant (XDR) Type IV Secretion System-Encoding Plasmid in Acinetobacter.
The study characterizes the XDR plasmid p1AB5075, which harbors multiple antibiotic resistance genes, including blaGES-11, aac(6')-Ib10, ant(2")-Ia, aadA2, aph(3")-Ib, aph(6)-Id, cmlA1, dfrA7, sul1, and qacEΔ1, conferring resistance to various antibiotics such as beta-lactams, aminoglycosides, chloramphenicol, trimethoprim, and sulfonamides. The plasmid was successfully transferred to genetically diverse Acinetobacter strains, highlighting its potential for spreading resistance.
Molecular Identification and Antimicrobial Resistance Characteristics of Extended-Spectrum Beta-Lactamase Producing Klebsiella pneumoniae Isolated from Captive Wild and Migratory Birds.
The study identified extended-spectrum beta-lactamase (ESBL)-producing Klebsiella pneumoniae in captive wild and migratory birds in Bangladesh, highlighting the presence of resistance genes such as bla TEM-1&2, bla SHV-1, bla OXA-1,4&30, strA, tetA, and sul1, which contribute to multidrug resistance.
Occurrence and Drivers of Antibiotic Resistance Genes Carried by Bacteriophages in Soils Following Different Fertilization Treatments.
The study identified 19 pARG subtypes in soils with different fertilization treatments, highlighting the impact of organic fertilizers on the diversity and abundance of antibiotic resistance genes carried by bacteriophages.
Genomic insights into multidrug - resistant Salmonella enterica isolates from pet dogs and cats.
The study identified multiple AMR genes in multidrug-resistant Salmonella enterica isolates from pet dogs and cats, including aac(6')-Iaa, aadA1, aadA2, blaTEM-1B, qacL, sul3, tet(A), qnrS1, fosA7, dfrA12, cmlA1, aph(3')-Ib, aph(6)-Id, blaCTX-M-55, blaTEM-215, and floR, which confer resistance to various antibiotics such as ampicillin, tetracycline, sulfamethoxazole, ciprofloxacin, and chloramphenicol.
Acquired antibiotic resistance of Pseudomonas spp., Escherichia coli and Acinetobacter spp. in the Western Balkans and Hungary with a One Health outlook.
The study identifies various acquired antibiotic resistance genes in Pseudomonas spp., Escherichia coli, and Acinetobacter spp. in the Western Balkans and Hungary, including beta-lactamases like bla VIM-2-like, bla NDM-1, bla OXA-23, and bla OXA-66, aminoglycoside resistance genes such as aacA4, aadA2, and aphA, sulfonamide resistance gene sul1, and others. These genes confer resistance to multiple antibiotics, highlighting the complexity of antimicrobial resistance in the region.
Acquired antibiotic resistance of Pseudomonas spp., Escherichia coli and Acinetobacter spp. in the Western Balkans and Hungary with a One Health outlook.
The study identifies various acquired antibiotic resistance genes in Pseudomonas spp., Escherichia coli, and Acinetobacter spp. in the Western Balkans and Hungary, including beta-lactamases like bla VIM-2-like, bla NDM-1, bla OXA-23, and bla OXA-66, aminoglycoside resistance genes such as aacA4, aadA2, and aphA, sulfonamide resistance gene sul1, and others. These genes confer resistance to multiple antibiotics, highlighting the complexity of antimicrobial resistance in the region.
Genomic features of three major diarrhoeagenic Escherichia coli pathotypes in India.
The study identifies a variety of acquired antimicrobial resistance (AMR) genes in diarrhoeagenic Escherichia coli (DEC) strains from India, highlighting the prevalence of resistance to multiple antibiotic classes, including aminoglycosides, beta-lactams, sulfonamides, and tetracyclines. Key AMR genes include blaTEM-105, strB, strA, mphA, sul1, sul2, addA1-pm, tetA, tetB, blaCTX-M15, blaCTX-M27, and blaDHA-1. Additionally, mutations in the quinolone resistance-determining regions (QRDRs) of gyrA and parC were found to contribute to fluoroquinolone resistance.
Prevalence and antimicrobial resistance of Salmonella enterica isolated from cattle farms in Inner Mongolia.
The study identified several AMR genes in Salmonella enterica isolates from Inner Mongolia, including bla TEM-1, cmlA, tetA, tetB, tetM, aadA2, aph(3')-IIa, aacC4, aac(3)-IIa, sul1, sul3, oqxA, and oqxB, which confer resistance to beta-lactams, chloramphenicol, tetracyclines, aminoglycosides, sulfonamides, and quinolones.
Diversity versus clonality in carbapenem-resistant A. baumannii: a two-year surveillance study in four intensive care units at a large teaching hospital in Rome, Italy.
The study identified carbapenem-resistant Acinetobacter baumannii isolates carrying the blaOXA-23 gene and aminoglycoside resistance genes such as armA, aadA2, aph(3')-VIa, and ant(2")-Ia. Other resistance genes included mph(E), msr(E), sul1, sul2, and tet(B).
Taxonomic and phenotypic characterization of a novel Providencia species: Providencia lanzhouensis sp. nov.
The study identifies Providencia lanzhouensis sp. nov., a novel species with multiple antimicrobial resistance genes, including aadA1, aadA2, aph(6)-Id, aph(3'')-Ib, aph(3')-Ia, sat2, sul2, ere(A), dfrA32, floR, tetC, and qnrD1, which confer resistance to aminoglycosides, streptomycin, sulfonamides, macrolides, trimethoprim, phenicols, tetracyclines, and quinolones.
Plasmid diversity in Klebsiella pneumoniae ST307 co-producing KPC plus NDM recovered during the COVID-19 pandemic.
The study characterizes the plasmid diversity in Klebsiella pneumoniae ST307 isolates co-producing KPC and NDM carbapenemases, identifying multiple resistance genes and plasmid types involved in carbapenem resistance.
Genomic characterization of an ESBL-producing Klebsiella pneumoniae ST37 recovered from a hospitalized patient in Armenia.
The study identified several AMR genes in the ESBL-producing K. pneumoniae ST37 isolate ARM02, including blaTEM-1D, blaSHV-11, dfrA14, sul2, strA, strB, and blaCTX-M-15, which were directly linked to the observed resistance phenotypes.
Unveiling the Genetic Diversity and Antimicrobial Resistance Profiles of Salmonella Population From 2016 to 2020 in Thai Canal Water.
The study identified 50 acquired resistance genes and seven chromosomal-mediated gene mutations in Salmonella populations from Thai canal water, highlighting the prevalence of multidrug-resistant strains and the diversity of resistance mechanisms.
Genomic profiling of cefotaxime-resistant Haemophilus influenzae from Norway and Sweden reveals extensive expansion of virulent multidrug-resistant international clones.
The study identifies the expansion of multidrug-resistant Haemophilus influenzae clones with cefotaxime resistance, primarily due to mutations in the ftsI gene encoding penicillin-binding protein 3 (PBP3). These mutations lead to cross-resistance to multiple beta-lactam antibiotics.
An NGS-assisted diagnostic workflow for culture-independent detection of bloodstream pathogens and prediction of antimicrobial resistances in sepsis.
The study evaluated the diagnostic performance of PISTE™ technology, an NGS-based workflow for detecting bloodstream pathogens and predicting antimicrobial resistance. It showed high accuracy in identifying pathogens and predicting resistance genes, including beta-lactamases, carbapenemases, aminoglycoside modifying enzymes, tetracycline efflux pumps, and quinolone resistance proteins.
Antibiotic resistance and novel Sequence Types of Klebsiella spp. in human, animal, and food sources: a One Health perspective from Northern Nigeria.
The study identified various AMR genes in Klebsiella spp. isolates from human, animal, and food sources, including strB, qnrS1, sul2, tetA, dfrA14, blaTEM-1, and blaSHV-11, which conferred resistance to multiple antibiotics.
Comparative Analysis of Phenotypic and Genotypic Antibiotic Susceptibility of Pasteurella multocida Isolated from Various Host Species in France and Hungary.
The study identified the most prevalent resistance genes in P. multocida as str A, sul 2, and tet H. Mutations in gyr A were associated with fluoroquinolone resistance.
Antimicrobial Resistance and Genomic Characterization of an Escherichia coli Strain Harboring p0111 and an IncX1-Type Plasmid, Isolated from the Brain of an Ostrich.
The study identifies multiple antimicrobial resistance genes in an Escherichia coli strain isolated from an ostrich, including bla CTX-M-55, rmtB, sul1, APH(6)-Id, tet(A), AAC(3)-IIc, aadA2, bla TEM-1B, and floR, which confer resistance to various antibiotics such as cephalosporins, aminoglycosides, sulfonamides, tetracyclines, and chloramphenicol.
Genomic Characterization of Pan-Drug Resistant Klebsiella pneumoniae KPNW Isolated From UTI Patient in Bangladesh.
The study identifies 42 antimicrobial resistance (AMR) genes in the pan-drug resistant Klebsiella pneumoniae isolate KPNW, including beta-lactamases (bla CTX-M-15, bla NDM-1, bla OXA-1, bla TEM-63, bla TEM-104, bla SHV-28), tetracycline resistance genes (tet(A)), and efflux pump genes (oqxA, oqxB, marA, marR, ompK37, pbp3, crp, h-ns, kpnG, kpnH, parC, rsmA). Additionally, the isolate shows resistance to polymyxin B and colistin through modifications in lipid A (eptB, arnT, lptD, msbA, vanG) and other mechanisms.
Genetic diversity, virulence genes, antimicrobial resistance, and biofilm formation of Klebsiella pneumoniae isolated from bovine mastitis milk in South Korea.
The study identified several AMR genes in K. pneumoniae isolates from bovine mastitis milk in South Korea, including blaSHV, strA, strB, sulI, sulII, tetA, tetB, tetC, floR, dfrXII, blaTEM, blaCTX-M, and blaOXA, which confer resistance to various antibiotics such as ampicillin, gentamicin, trimethoprim/sulfamethoxazole, tetracycline, chloramphenicol, and others.
Molecular characterization of drug-resistance genes and dynamics of multidrug-resistant Salmonella spp. in waterfowl: a pre- and post-antibiotic ban surveillance in Guangdong, China from 2013 to 2023.
The study identified several AMR genes in Salmonella isolates from waterfowl in Guangdong, China, including bla CTX-M, bla TEM, bla OXA, aad A1, aad A2, aac C2, aac (3)-IV, aph (3’)-I, qnr A, qnr S, clm A, flo R, tet (A), and Sul II. These genes were associated with resistance to various antibiotics such as β-lactams, aminoglycosides, quinolones, chloramphenicol, tetracyclines, and sulfonamides.
Community gut colonization by tet(X4)-positive multidrug-resistant Escherichia coli in healthy individuals from urban residents in Shenzhen, China.
The study identifies tet(X4)-positive multidrug-resistant E. coli in healthy individuals from urban areas in Shenzhen, China, highlighting the presence of tigecycline resistance and other resistance genes in the community gut microbiota.
Community gut colonization by tet(X4)-positive multidrug-resistant Escherichia coli in healthy individuals from urban residents in Shenzhen, China.
The study identifies tet(X4)-positive multidrug-resistant E. coli in healthy individuals from urban areas in Shenzhen, China, highlighting the presence of tigecycline resistance and other resistance genes in the community gut microbiota.
Antibiotic resistance in mastitis-causing bacteria: Exploring antibiotic-resistance genes, underlying mechanisms, and their implications for dairy animal and public health.
The study identifies several AMR genes and mutations in Staphylococcus aureus and coagulase-negative staphylococci associated with mastitis, including blaZ, mecA, tetK, tetM, aphA3, aacA-aphD, aadD, ermA, msrA, mphC, lnuB, and vanA, which confer resistance to various antibiotics such as β-lactams, tetracyclines, aminoglycosides, macrolides, and glycopeptides.
Prevalence and Genetic Characterization of Antimicrobial-resistant Escherichia coli from Wild Boar Meat in Japan.
The study identified antimicrobial-resistant Escherichia coli in wild boar meat in Japan, with resistance genes including blaTEM, strA, strB, aacC2, aphA1, tetA, and tetB.
Emerging threat of antimicrobial resistance determinants and plasmid replicon types acquisition by Escherichia coli of poultry and other food-producing animal origin in China: local findings with global implications.
The study identifies multiple antimicrobial resistance genes in Escherichia coli from poultry and other food-producing animals in China, highlighting the prevalence of beta-lactamases, tetracycline resistance genes, aminoglycoside modifying enzymes, quinolone resistance genes, and sulfonamide resistance genes.
Multidrug resistant hypervirulent ST307 clone from genomic surveillance of extended spectrum beta-lactamase-producing Klebsiella pneumoniae species complex in East Africa.
The study identifies multiple AMR genes, including blaCTX-M-15, blaTEM-1D, aac(6')-Ib-cr, aadA16, strB, qnrS1, sul2, sul1, catII.2, tet(A), dfrA14, arr-3, and mphA, in ESBL-KpSC isolates from East Africa, highlighting the prevalence of multidrug resistance.
Genomic insights into novel ST7947 carbapenem-resistant hypervirulent Klebsiella pneumoniae: a threat from an Indian hospital setting.
The study identifies several AMR genes and mutations in the novel ST7947 carbapenem-resistant hypervirulent Klebsiella pneumoniae isolate BB-7, including bla CTX-M-15, bla SHV-28, bla TEM-1, bla OXA-1, bla OXA-232, armA, aadA2, baeR, tetD, adeF, emrR, AAC(6')-Ib-cr6, catI, sul1, mphE, msrE, dfrA1, oqxA, and fosA, as well as mutations in GyrA, ParC, OmpA, OmpK37, and ArnT that confer resistance to multiple antibiotics.
Characterization of Enterobacter cloacae complex clinical isolates: comparative genomics and the role of the efflux pump AcrAB-TolC over-expression and NDM-1 production.
The study characterizes carbapenem-resistant Enterobacter cloacae complex isolates, highlighting the roles of the AcrAB-TolC efflux pump over-expression and the bla NDM-1 carbapenemase in conferring resistance. Multiple resistance genes, including bla NDM-1, acrAB-tolC, and various beta-lactamases, aminoglycoside-modifying enzymes, and sulfonamide resistance genes, were identified and validated.
Global geographic and genomic epidemiology analysis of carbapenem-resistant Escherichia coli carrying bla(NDM-9).
The study characterizes bla NDM-9 -carrying carbapenem-resistant Escherichia coli (CREC) and identifies various antibiotic resistance genes (ARGs) contributing to multidrug resistance. It highlights the role of mobile genetic elements in the dissemination of bla NDM-9 and emphasizes the importance of surveillance for these high-risk clones.
Global emergence of Acinetobacter baumannii International Clone 12 predominantly found in the Middle East.
The study identifies multiple acquired antimicrobial resistance genes in Acinetobacter baumannii International Clone 12, including bla OXA-23, bla GES-11, bla GES-12, bla GES-22, bla GES-35, bla CARB-16, bla CARB-49, aphA6a, aadB, strA, strB, cmlA1, aadA2b, sul1, drfA7, dfrA1, qacE, tet(B), tet(X3), msr(E), mph(E), bla TEM-1B, and aacC3. These genes contribute to resistance against various antibiotics, highlighting the complexity of resistance mechanisms in this clone.
Genetic features of bla(NDM-1) harboring Klebsiella pneumoniae isolates from Kerman, Iran.
The study identifies bla(NDM-1) as a key carbapenem resistance gene in Klebsiella pneumoniae isolates from Kerman, Iran, highlighting its role in multidrug resistance and the need for monitoring its spread.
Research of antimicrobial resistance and its associated genes distribution in Escherichia coli from diarrheic calves in the Ulagai region of China.
The study identified several antimicrobial resistance genes in E. coli isolates from diarrheic calves in the Ulagai region of China, including sul2, TEM-1, tetR, strB, QacH, floR, and CTXM-55, which were associated with resistance to various antibiotics.
Genomic diversity and antimicrobial resistance of Vibrio cholerae isolates from Africa: a PulseNet Africa initiative using nanopore sequencing to enhance genomic surveillance.
The study identified a high prevalence of trimethoprim resistance genes (dfrA1, dfrA15, dfrA31) and other resistance genes such as floR, strA, strB, varG, blaCARB-2, aadA1, aadA2, sul1, sul2, catB9, tet(C), tet(G), tet(59), qacEdelta, and blaCMY-4 in Vibrio cholerae isolates from Africa. Fluoroquinolone resistance mutations (gyrA_S83I and parC_S85L) and nitrofuran resistance mutations (nfsA_R169C and nfsB_Q5*) were also prevalent.
Genomic diversity and antimicrobial resistance of Vibrio cholerae isolates from Africa: a PulseNet Africa initiative using nanopore sequencing to enhance genomic surveillance.
The study identified a high prevalence of trimethoprim resistance genes (dfrA1, dfrA15, dfrA31) and other resistance genes such as floR, strA, strB, varG, blaCARB-2, aadA1, aadA2, sul1, sul2, catB9, tet(C), tet(G), tet(59), qacEdelta, and blaCMY-4 in Vibrio cholerae isolates from Africa. Fluoroquinolone resistance mutations (gyrA_S83I and parC_S85L) and nitrofuran resistance mutations (nfsA_R169C and nfsB_Q5*) were also prevalent.
A Monitoring Method to Evaluate the Accumulation of Antimicrobial-Resistance Genes in Gram-Negative Bacteria Distributed in Environmental Water.
The study identified multiple antimicrobial resistance genes (ARGs) in Gram-negative bacteria isolated from environmental water samples, including bla NDM-5, bla CTX-M-27, bla DHA-1, and others, indicating the presence of carbapenem-resistant and extended-spectrum beta-lactamase-producing bacteria in the Vietnamese VAC ecosystem.
Molecular characterization of mcr-1.1-harboring multidrug-resistant Escherichia coli isolates from chicken in the United Arab Emirates: implications for one health surveillance.
The study identified mcr-1.1-harboring multidrug-resistant E. coli isolates from chicken in the UAE, highlighting the presence of various AMR genes and mutations contributing to resistance against multiple antibiotics, including colistin, beta-lactams, quinolones, and aminoglycosides.
No comments yet. Be the first to comment!