Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA7
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| AadA7 | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 40 | STREPTOMYCIN, streptomycin +3 | Escherichia coli +22 | France|Egypt, Australia|India, Atlantic Canada, Egypt, Brazil, Croatia, Shandong province, China, France, Nigeria, Canada, Spain, India, Ethiopia|Kenya, Switzerland, Saudi Arabia, Bangladesh, China, United States, Zimbabwe, Thailand, Guangdong, China, Bolivia, Algeria | 2000, 2004, 2006, 2007, 2008, 2015, 2016, 2018, 2019, 2020, 2021, 2022, 2023, 2024, 2025 | AF234167.1 | AAF79946.1 |
| ANT(3'') | Card Database | 1 | - | Vibrio fluvialis | - | - | AB114632.1 | BAD00739.1 |
| aadA7 | ResFinder Database | 1 | STREPTOMYCIN, SPECTINOMYCIN | Escherichia coli, Vibrio fluvialis | - | 2000 | AF224733, AB114632 | - |
| aadA7_1 | Reslit | 1 | aminoglycosides | Salmonella enterica | Hanoi, Vietnam | 2023 | SRR16611133|SRR16611134|SRR16611135|SRR16611136|SRR16611137|SRR16611138|SRR16611139|SRR16611140 | - |
Antibiotic Resistance in the ECOR Collection: Integrons and Identification of a Novel aad Gene.
The study identifies a novel aadA7 gene in the ECOR collection of Escherichia coli strains, which confers resistance to streptomycin and spectinomycin.
Antibiotic resistance in the ECOR collection: integrons and identification of a novel aad gene.
Antibiotic resistance in the ECOR collection: integrons and identification of a novel aad gene.
Antibiotic resistance in the ECOR collection: integrons and identification of a novel aad gene., New aminoglycoside acetyltransferase gene, aac(3)-Id, in a class 1 integron from a multiresistant strain of Vibrio fluvialis isolated from an infant aged 6 months.
New aminoglycoside acetyltransferase gene, aac(3)-Id, in a class 1 integron from a multiresistant strain of Vibrio fluvialis isolated from an infant aged 6 months.
New aminoglycoside acetyltransferase gene, aac(3)-Id, in a class 1 integron from a multiresistant strain of Vibrio fluvialis isolated from an infant aged 6 months.
New aminoglycoside acetyltransferase gene, aac(3)-Id, in a class 1 integron from a multiresistant strain of Vibrio fluvialis isolated from an infant aged 6 months.
Mechanism of drug resistance in clonally related clinical isolates of Vibrio fluvialis isolated in Kolkata, India.
Variant Salmonella genomic island 1-L antibiotic resistance gene cluster in Salmonella enterica serovar Newport.
The study identifies a new variant of the Salmonella genomic island 1 (SGI1-L) in a Salmonella enterica serovar Newport isolate, containing the dfrA15 gene cassette for trimethoprim resistance, and a class 1 integron with aacC5 and aadA7 gene cassettes for gentamicin, streptomycin, and spectinomycin resistance.
SGI1-K, a variant of the SGI1 genomic island carrying a mercury resistance region, in Salmonella enterica serovar Kentucky.
The study identifies the aacCA5 and aadA7 gene cassette array in SGI1-K, which confers resistance to gentamicin, streptomycin, and spectinomycin in Salmonella enterica serovar Kentucky.
Coproduction of novel 16S rRNA methylase RmtD and metallo-beta-lactamase SPM-1 in a panresistant Pseudomonas aeruginosa isolate from Brazil.
Transferable, multiple antibiotic and mercury resistance in Atlantic Canadian isolates of Aeromonas salmonicida subsp. salmonicida is associated with carriage of an IncA/C plasmid similar to the Salmonella enterica plasmid pSN254.
The study identifies multiple antibiotic and mercury resistance genes carried by an IncA/C plasmid in Atlantic Canadian isolates of Aeromonas salmonicida subsp. salmonicida, including aadA7, floR, tetA, sulII, strA, strB, blaCMY-2, and a mercury resistance operon.
Characterization of antimicrobial resistance and class 1 integrons in Enterobacteriaceae isolated from Mediterranean herring gulls (Larus cachinnans).
Non-Typhoidal Salmonella in poultry meat and diarrhoeic patients: prevalence, antibiogram, virulotyping, molecular detection and sequencing of class I integrons in multidrug resistant strains.
The study identified several AMR genes, including aac(3)-Id, aadA2, aadA4, aadA7, dfrA15, lnuF, sat, and estX, in multidrug-resistant Salmonella strains isolated from poultry meat and diarrheic patients in Egypt.
Intraclonal Genome Stability of the Metallo-β-lactamase SPM-1-producing Pseudomonas aeruginosa ST277, an Endemic Clone Disseminated in Brazilian Hospitals.
The study identifies the blaSPM-1 gene as a key factor in carbapenem resistance in Pseudomonas aeruginosa ST277 isolates, along with other resistance genes in genomic islands.
Broad-spectrum resistance of Pseudomonas aeruginosa from shellfish: infrequent acquisition of novel resistance mechanisms.
The study identified the blaTEM-116 gene, sul1 gene, and aadA7 gene cassette in Pseudomonas aeruginosa isolates from shellfish, highlighting the presence of intrinsic and acquired resistance mechanisms in marine environments.
Serotype, antimicrobial susceptibility and genotype profiles of Salmonella isolated from duck farms and a slaughterhouse in Shandong province, China.
The study identified multiple antimicrobial resistance genes, including blaTEM, sul2, aadA7, aac3-Id, aadA5, and dfrA17, in Salmonella isolates from duck farms and a slaughterhouse in Shandong, China. High levels of resistance to various antibiotics were observed, highlighting the need for improved antimicrobial stewardship.
Two New SGI1-LK Variants Found in Proteus mirabilis and Evolution of the SGI1-HKL Group of Salmonella Genomic Islands.
The study identifies two new SGI1-LK variants, SGI1-LK1 and SGI1-LK2, in Proteus mirabilis isolates, highlighting the evolutionary dynamics of the SGI1-HKL group of Salmonella genomic islands.
Characterization of a SPM-1 metallo-beta-lactamase-producing Pseudomonas aeruginosa by comparative genomics and phenotypic analysis.
The study characterizes the multidrug-resistant Pseudomonas aeruginosa isolate CCBH4851, identifying several AMR genes including blaSPM-1, sul1, rmtD, blaOXA-56, aac(6')-I, aadA7, cmx, and bcr, as well as mutations in oprD and mexZ contributing to resistance.
Genomic Analysis of Antimicrobial Resistance and Resistance Plasmids in Salmonella Serovars from Poultry in Nigeria.
The study identified various antimicrobial resistance genes in Salmonella isolates from Nigerian poultry, including aac(6')-Ia, aac(6')-Ib, aadA7, aph(3")-Ia, aph(3")-Ib, aph(6')-Id, aph(6')-Ic, aac(3)-Ia, aac(3)-IIa, aac(3)-IVa, aac(6')-IIa, aac(3)-Id, sul1, sul2, sul3, tet(A), tet(M), qnrS1, qnrB19, blaTEM, dfrA14, dfrA15, dfrA17, catA1, cmlA1, and floR. Mutations in gyrA (Ser83Phe, Asp87Tyr) and parC (Thr57Ser, Ser80Ile) were also associated with resistance to nalidixic acid and ciprofloxacin.
A One-Health Genomic Investigation of Gentamicin Resistance in Salmonella from Human and Chicken Sources in Canada, 2014 to 2017.
The study identified several aminoglycoside-modifying enzymes, including aac(3)-VIa, aac(3)-IId, aac(3)-Id, aac(3)-IVa, aac(3)-IIa, ant(2′′)-Ia, aac(6′)-Ib-cr, aadA2, aadA7, aadA1, ant(3′′)-Ia, aac(6′)-Ib3, and rmtB, as key contributors to gentamicin resistance in Salmonella isolates from both human and chicken sources in Canada.
Genomic Analysis of Ciprofloxacin-Resistant Salmonella enterica Serovar Kentucky ST198 From Spanish Hospitals.
The study identified several AMR genes and mutations associated with ciprofloxacin resistance in Salmonella enterica serovar Kentucky ST198 isolates from Spanish hospitals. Key findings include the presence of blaTEM-1B, aacA5, aadA7, sul1, tet(A), catA1, and aac(6′)-Ib genes, along with mutations in gyrA (Ser83Phe) and parC (Thr57Ser, Ser80Ile).
Genome analysis and virulence gene expression profile of a multi drug resistant Salmonella enterica serovar Typhimurium ms202.
The study identified multiple antimicrobial resistance genes in the multi-drug resistant Salmonella enterica serovar Typhimurium ms202 strain, including fosA7, sul1, aadA7, aac(6')-laa, tet(A), and qacE, which confer resistance to various antibiotics such as fosfomycin, sulfamethoxazole, spectinomycin, amikacin, tetracycline, and disinfectants.
Genomic and Evolutionary Analysis of Salmonella enterica Serovar Kentucky Sequence Type 198 Isolated From Livestock In East Africa.
The study identified multiple antimicrobial resistance genes in Salmonella enterica serovar Kentucky ST198 isolates from East Africa, including aac(3)-Id, aadA7, strA, strB, bla TEM-1B, sul1, and tet(A), which confer resistance to aminoglycosides, streptomycin, ampicillin, sulfamethoxazole, and tetracycline. Mutations in gyrA and parC were associated with ciprofloxacin resistance.
Epidemiological links and antimicrobial resistance of clinical Salmonella enterica ST198 isolates: a nationwide microbial population genomic study in Switzerland.
The study identifies several AMR genes and mutations associated with ciprofloxacin resistance in Salmonella enterica ST198 isolates, including aac(3)-Id, aadA7, bla TEM-1b, sul1, tetA, qnrB1, qnrS1, bla CTX-M-14b, bla VEB-8, and bla OXA-48. Additionally, inactivating mutations in ramR and acrB were found to contribute to high-level ciprofloxacin resistance.
Whole-Genome Analysis of Antimicrobial-Resistant Salmonella enterica Isolated from Duck Carcasses in Hanoi, Vietnam.
The study identified 43 antibiotic resistance genes in Salmonella enterica isolates from duck carcasses in Hanoi, Vietnam, including genes conferring resistance to multiple antibiotic classes such as aminoglycosides, beta-lactams, quinolones, and tetracyclines.
Antimicrobial resistance and genomic characterization of Salmonella enterica isolates from chicken meat.
The study identified multiple antimicrobial resistance genes in Salmonella enterica isolates from chicken meat, including aminoglycoside, beta-lactam, quinolone, tetracycline, sulfonamide, and phenicol resistance genes. These genes were detected using whole genome sequencing and correlated with phenotypic resistance profiles.
Multidrug-resistant non-typhoidal Salmonella of public health significance recovered from migratory birds in Bangladesh.
The study identified multidrug-resistant non-typhoidal Salmonella in migratory birds in Bangladesh, highlighting the presence of various AMR genes such as blaCARB-2, floR, sul1, tet(G), dfrA1, and mutations in gyrA and parC associated with quinolone resistance.
Poultry production as the main reservoir of ciprofloxacin- and tigecycline-resistant extended-spectrum β-lactamase (ESBL)-producing Salmonella enterica serovar Kentucky ST198.2-2 causing human infections in China.
The study identifies several AMR genes and mutations in Salmonella enterica serovar Kentucky ST198.2-2, including blaCTX-M-14b, blaCTX-M-55, blaTEM-1B, aadA7, aph(3')-Ia, aac(3)-IId, rmtB, tet(A), sul1, dfrA14, floR, lnu(F), mph(A), arr-2, and fosA3, which confer resistance to various antibiotics. Mutations in gyrA and parC also contribute to fluoroquinolone resistance.
Causal-ARG: A Causal Representation Learning Framework for Annotating Antimicrobial Resistance Genes
The paper proposes a causality-guided framework called Causal-ARG for annotating properties of antibiotic resistance genes (ARGs), focusing on antibiotic class, resistance mechanism, and transferability.
Comparison of genotypic and phenotypic antimicrobial resistance profiles of Salmonella enterica isolates from poultry diagnostic specimens.
The study identified 31 AMR genes in 97 Salmonella enterica isolates from poultry, including aac(3)-IId, aac(3)-IVa, aac(3)-VIa, aac(6′)-Ib4, ant(2′′)-Ia, grdA, aph(3′)-Ia, aph(3′)-IIa, aadA1, aadA2, aadA7, aadA13, aph(3′)-Ib, aph(6)-Ic, aph(6)-Id, aph(4)-Ia, blaCMY-2, blaCTX-M-1, blaHER-3, blaTEM-1, floR, tetA, tetB, tetC, dfrA12, sul1, sul2, fosA7, qnrB19, ble, and mcr-9.
Persistent Colonization of Ciprofloxacin-Resistant and Extended-Spectrum β-Lactamase (ESBL)-Producing Salmonella enterica Serovar Kentucky ST198 in a Patient with Inflammatory Bowel Disease.
The study characterizes three ciprofloxacin-resistant and extended-spectrum β-lactamase (ESBL)-producing Salmonella enterica serovar Kentucky ST198 strains from a single patient with inflammatory bowel disease, highlighting their multidrug-resistant profile and potential epidemiological links to strains from chicken meat.
Host species shapes genotype, antimicrobial resistance, and virulence profiles of enterotoxigenic Escherichia coli (ETEC) from livestock in the United States.
The study identifies distinct antimicrobial resistance (AMR) gene profiles in bovine and swine enterotoxigenic Escherichia coli (ETEC) isolates, highlighting differences in the prevalence of specific AMR genes and plasmid replicons between the two host species.
Genomic profiling of pan-drug resistant proteus mirabilis Isolates reveals antimicrobial resistance and virulence gene landscape.
The study identified multiple antimicrobial resistance genes in pan-drug resistant Proteus mirabilis isolates, including genes conferring resistance to aminoglycosides, beta-lactams, tetracyclines, sulfonamides, and others. These genes were found on the chromosome and contributed to the isolates' resistance to various antibiotic classes.
Biofilm enhanced the mitigations of antibiotics and resistome in sulfadiazine and trimethoprim co-contaminated soils.
The study identifies several AMR genes, including aadA7, aac(6')-II, aac(3)-iid, aadD, tetA, tetM, tetX, and sul2, in Arthrobacter sp. D2, which are involved in resistance to aminoglycosides, tetracyclines, and sulfonamides. These genes were experimentally validated using high-throughput qPCR analysis.
Highly drug resistant clone of Salmonella Kentucky ST198 in clinical infections and poultry in Zimbabwe.
The study identifies multiple AMR genes and mutations in Salmonella Kentucky ST198 strains from Zimbabwe, highlighting their multidrug resistance and the presence of specific resistance mechanisms such as blaCTX-M-14.1 and mutations in gyrA and parC.
Unveiling the Genetic Diversity and Antimicrobial Resistance Profiles of Salmonella Population From 2016 to 2020 in Thai Canal Water.
The study identified 50 acquired resistance genes and seven chromosomal-mediated gene mutations in Salmonella populations from Thai canal water, highlighting the prevalence of multidrug-resistant strains and the diversity of resistance mechanisms.
Antimicrobial Resistance of Salmonella and Characterization of Two Mcr-1-Harboring Isolates from Pork Products in Guangdong, China.
Two mcr-1-harboring Salmonella Kentucky ST198 isolates were identified, showing resistance to multiple antibiotics including colistin, tetracycline, and fluoroquinolones. The study highlights the presence of complex resistance determinants such as the multidrug resistance region (MRR) and SGI1-KI.
First nationwide survey on Pseudomonas aeruginosa in Bolivia: susceptibility profiles, resistome, and genomic epidemiology.
The study identified multiple carbapenemases, extended-spectrum beta-lactamases, and 16S rRNA methyltransferases in multidrug-resistant Pseudomonas aeruginosa isolates from Bolivia, highlighting the prevalence of high-risk clones and resistance mechanisms.
Genomic characterisation of multidrug-resistant Salmonella enterica serovar Kentucky ST198 isolates from various sources in Algeria, North Africa.
The study identified multiple AMR genes and chromosomal mutations in multidrug-resistant Salmonella enterica serovar Kentucky ST198 isolates from Algeria, including bla TEM-1B, bla CTX-M-15, aac(3)-Id, aadA7, sul1, tet(A), mph(A), qnrB19, cmlA1, and floR, along with mutations in gyrA and parC genes that confer resistance to ciprofloxacin.
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