Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
fosfomycin efflux MFS transporter AbaF
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| AbaF | Card DatabaseReference Gene CatalogReslit | 10 | FOSFOMYCIN, fosfomycin | Acinetobacter baumannii ATCC 17978 +4 | Norway|China, Thailand, China, Vietnam, China|Korea|Japan | 2017, 2020, 2021, 2022, 2025 | CP000521.1 | ABO11759.2 |
| Aba F | Reslit | 1 | fosfomycin | Acinetobacter baumannii | South Africa | 2022 | PRJNA765178 | - |
Fosfomycin resistance in Acinetobacter baumannii is mediated by efflux through a major facilitator superfamily (MFS) transporter-AbaF.
Fosfomycin resistance in Acinetobacter baumannii is mediated by efflux through a major facilitator superfamily (MFS) transporter-AbaF.
Acinetobacter baumannii Efflux Pumps and Antibiotic Resistance.
The study identifies several efflux pumps in Acinetobacter baumannii, including AdeABC, AbeM, AbaF, and AbeS, which contribute to multidrug resistance. These pumps are involved in the efflux of various antibiotics and other antimicrobial agents.
Antibiotic Resistance Profiles, Molecular Mechanisms and Innovative Treatment Strategies of Acinetobacter baumannii.
The paper discusses the antibiotic resistance profiles and molecular mechanisms of Acinetobacter baumannii, highlighting the presence of various beta-lactamases such as blaOXA-23, blaOXA-51, blaOXA-24/40, blaOXA-58, blaOXA-143, blaOXA-235, blaIMP, blaVIM, and blaNDM, as well as aminoglycoside-modifying enzymes like aac(6')-Ib, aph(3')-Ia, and ant(2'')-Ia. It also identifies efflux pumps such as adeABC and tetracycline resistance genes like tet(A).
Antibiotic Resistance and Phylogeny of Pseudomonas spp. Isolated over Three Decades from Chicken Meat in the Norwegian Food Chain.
The study identified several AMR genes and mutations in Pseudomonas spp. isolated from chicken meat in Norway, including beta-lactamases, efflux pumps, and genes involved in resistance to aminoglycosides, fluoroquinolones, and colistin.
Synergism of imipenem with fosfomycin associated with the active cell wall recycling and heteroresistance in Acinetobacter calcoaceticus-baumannii complex.
The study identifies carbapenemase genes blaOXA-24, blaOXA-23, and blaOXA-58 along with blaIMP in various Acinetobacter isolates, contributing to carbapenem resistance. It also highlights the role of cell wall recycling pathways and heteroresistance in modulating the effectiveness of imipenem-fosfomycin synergy.
Whole genome sequence of pan drug-resistant clinical isolate of Acinetobacter baumannii ST1890.
The study identified multiple antibiotic resistance genes in the pan-drug-resistant Acinetobacter baumannii strain VJR422, including genes encoding beta-lactamases, aminoglycoside-modifying enzymes, and efflux pumps, contributing to resistance against various antibiotic classes.
Molecular characterisation of Acinetobacter baumannii isolates from bloodstream infections in a tertiary-level hospital in South Africa.
The study identified colistin-resistant Acinetobacter baumannii isolates with resistance genes including bla OXA-23, bla NDM-1, lps B, and various efflux pumps. These isolates exhibited extensive drug resistance (XDR) and were associated with sequence types ST1 and ST2.
Genomic characteristics, virulence potential, antimicrobial resistance profiles, and phylogenetic insights into Nocardia cyriacigeorgica.
The study identified several antimicrobial resistance genes in Nocardia cyriacigeorgica, including VanSO and VanRO for vancomycin resistance, erm(O)-Irm, srmB, and ermH for macrolide resistance, bla1 and bcl for beta-lactam resistance, CTX-M and KPC for cephalosporin and carbapenem resistance, tetA(58) and tetB(58) for tetracycline resistance, folC and folP for sulfonamide resistance, rbpA and rpoB2 for rifamycin resistance, murA and AbaF for fosfomycin resistance, cmlR for chloramphenicol resistance, and VatF and VatE for streptogramin resistance.
Genomic Characterization and Antibiotic Resistance Profiles of Acinetobacter baumannii Isolates From Intensive Care Units in Vietnam.
The study identifies multiple AMR genes in three CRAB isolates, including blaOXA-23, blaOXA-66, blaADC-198, blaADC-73, and various aminoglycoside modifying enzymes, efflux pumps, and sulfonamide resistance genes, highlighting the extensive multidrug resistance in these isolates.
Gut microbiome profiling of a migratory Anser serrirostris population reveals two groups with distinct pathogen and ARG contents.
The study identified two distinct gut microbiome groups (E1 and E2) in a migratory Anser serrirostris population, with E1 showing higher abundances of opportunistic pathogens and antibiotic resistance genes (ARGs). Key ARGs included beta-lactamase-encoding genes such as blaCTX-M, blaZ, blaCARB-1, blaADC, blaPDC, and blaOXA-213, which were more prevalent in E1.
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