abaR

View on PubMed

multidrug efflux pump

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

UniProt

Protein entries specific to abaR

AMR Rules

Browse AMR rules for abaR

Validation StatusCandidate

Overview

Mechanism: confers resistance to multiple antibiotics
Validation Method: whole-genome sequencing
Drug Classes: tetracycline, fluoroquinolones, aminoglycosides
Organisms: Acinetobacter baumannii
Geographic Location: Italy
Papers: 1
Databases: Reslit

Papers1

In Vitro Activity of Sulbactam-Durlobactam against Carbapenem-Resistant Acinetobacter baumannii Clinical Isolates: A Multicentre Report from Italy.

PMID 36010006 · 2022

The study evaluated the in vitro activity of sulbactam-durlobactam (SUL-DUR) against 141 carbapenem-resistant A. baumannii isolates. It identified several resistance genes including blaOXA-20, blaOXA-58, blaOXA-66, blaADC-25, aac(6')-Ib3, aac(6')-Ib-cr, and mutations in gyrA (S81L) and parC (V104I, D105E). Additionally, mutations in PBP3 (Q488K and Y528H) were found in SUL-DUR resistant isolates.

Gene Information

Gene Name: abaR
Allele: abaR
Encodes: multidrug efflux pump
Source Database: Reslit
Mechanism: confers resistance to multiple antibiotics
Confers Resistance To: tetracyclinefluoroquinolonesaminoglycosides
Organisms Tested In: • Acinetobacter baumannii
Geographic Location: Italy
Validation Method: whole-genome sequencing
Sequence Accession: CP063225|CP063226|CP063227|CP063228|CP063229|CP063230|CP063231|CP063232|CP063233|CP063234|CP063235

Comments (0)

No comments yet. Be the first to comment!

abaR

Gene Information

Browse AMR Genes

abaR

Gene Information