acr d

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efflux pump component

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

UniProt

Protein entries specific to acr d

AMR Rules

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Validation StatusCandidate

Overview

Mechanism: confers resistance to multiple antibiotics
Validation Method: PCR and WGS
Drug Classes: amoxicillin clavulanic acid, cefotaxime, ciprofloxacin, tetracycline
Organisms: Klebsiella pneumoniae
Geographic Location: Portugal
Papers: 1
Databases: Reslit

Papers1

Assessment of Antibiotic Resistance Among Isolates of Klebsiella spp. and Raoultella spp. in Wildlife and Their Environment from Portugal: A Positive Epidemiologic Outcome.

PMID 39861060 · 2025

The study identified a single multidrug-resistant (MDR) and extended-spectrum beta-lactamase (ESBL)-producing K. pneumoniae isolate from soil samples carrying multiple resistance genes, including bla CTX-M-15, bla TEM-1, bla SHV-28, bla OXA-1, qnr B1, oqx A, oqx B19, aac (6′)-Ibcr, sul 2, dfr A14, tet A, aph (6)-Id, aph (3″)-Ib, acr D, cat B3, and Int I1.

Gene Information

Gene Name: acr d
Allele: acr D
Encodes: efflux pump component
Source Database: Reslit
Mechanism: confers resistance to multiple antibiotics
Confers Resistance To: amoxicillin clavulanic acidcefotaximeciprofloxacintetracycline
Organisms Tested In: • Klebsiella pneumoniae
Geographic Location: Portugal
Validation Method: PCR and WGS
Sequence Accession: CP099015

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acr d

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acr d

Gene Information