ade a

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Resistance-nodulation-division efflux pump

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Validation StatusCandidate

Overview

Validation Method: whole-genome sequencing
Drug Classes: fluoroquinolones, lincosamides, macrolides, tetracycline
Organisms: Acinetobacter baumannii
Geographic Location: South Africa
Papers: 1
Databases: Reslit

Papers1

Molecular characterisation of Acinetobacter baumannii isolates from bloodstream infections in a tertiary-level hospital in South Africa.

PMID 35992699 · 2022

The study identified colistin-resistant Acinetobacter baumannii isolates with resistance genes including bla OXA-23, bla NDM-1, lps B, and various efflux pumps. These isolates exhibited extensive drug resistance (XDR) and were associated with sequence types ST1 and ST2.

Gene Information

Gene Name: ade a
Allele: ade A
Encodes: Resistance-nodulation-division efflux pump
Source Database: Reslit
Confers Resistance To: fluoroquinoloneslincosamidesmacrolidestetracycline
Organisms Tested In: • Acinetobacter baumannii
Geographic Location: South Africa
Validation Method: whole-genome sequencing
Sequence Accession: PRJNA765178

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