ade f

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Resistance-nodulation-division efflux pump

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

UniProt

Protein entries specific to ade f

AMR Rules

Browse AMR rules for ade f

Validation StatusCandidate

Overview

Validation Method: whole-genome sequencing
Drug Classes: fluoroquinolones, tetracycline, phenicols
Organisms: Acinetobacter baumannii
Geographic Location: India|China|Brazil, South Africa
Papers: 2
Databases: Reslit

Papers2

Molecular characterisation of Acinetobacter baumannii isolates from bloodstream infections in a tertiary-level hospital in South Africa.

PMID 35992699 · 2022

The study identified colistin-resistant Acinetobacter baumannii isolates with resistance genes including bla OXA-23, bla NDM-1, lps B, and various efflux pumps. These isolates exhibited extensive drug resistance (XDR) and were associated with sequence types ST1 and ST2.

Gene Information

Gene Name: ade f
Allele: ade F
Encodes: Resistance-nodulation-division efflux pump
Source Database: Reslit
Confers Resistance To: fluoroquinolonestetracycline
Organisms Tested In: • Acinetobacter baumannii
Geographic Location: South Africa
Validation Method: whole-genome sequencing
Sequence Accession: PRJNA765178

Comparative genomics reveals avian Acinetobacter baumannii as antimicrobial resistance reservoirs and bovine strains with elevated pathogenicity.

PMID 41444811 · 2025

Avian Acinetobacter baumannii strains were found to carry a significantly higher number of antimicrobial resistance genes compared to bovine and porcine strains, highlighting their potential role in the dissemination of antimicrobial resistance through animal origin foods.