Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
resistance-nodulation-cell division (RND) antibiotic efflux pump
Overview
The Role of the Two-Component System BaeSR in Disposing Chemicals through Regulating Transporter Systems in Acinetobacter baumannii.
The study identifies that the BaeSR two-component system regulates the expression of efflux pump genes adeA, adeB, adeI, adeJ, adeK, macA, macB, and tolC in Acinetobacter baumannii, contributing to tigecycline resistance. Deletion of baeR reduces the expression of these genes, leading to increased susceptibility to tannic acid and tigecycline.
Resistome metagenomics from plate to farm: The resistome and microbial composition during food waste feeding and composting on a Vermont poultry farm.
The study identified 50 unique antibiotic resistance genes (ARGs) in food waste, compost, and farm products, with a focus on aminoglycoside, tetracycline, and macrolide resistance. Key ARGs included aph(6)-1d, lmrD, mefA, mel, abeM, abeS, adeF, adeG, adeI, adeJ, adeK, emrD, sul2, tetH, tetM, tetO, tetW, and tetX, which were found in various samples and showed resistance to multiple drug classes.
Whole-genome sequencing for the characterization of resistance mechanisms and epidemiology of colistin-resistant Acinetobacter baumannii.
The study identified several beta-lactam resistance genes, including ADC-18, OXA-133, OXA-23, OXA-66, TEM-1, VIM-2, and RND efflux pumps (adeI, adeJ, adeK, adeN) in colistin-resistant Acinetobacter baumannii strains.
Resistance mechanisms of tigecycline in Acinetobacter baumannii.
The study identifies several efflux pumps, outer membrane permeability alterations, and antibiotic target modifications as key mechanisms of tigecycline resistance in Acinetobacter baumannii.
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