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Browse GenesadeT1

adeT1

membrane fusion protein

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to adeT1

Browse AMR rules for adeT1

Validation StatusCandidate

Overview

Mechanism: forms an active efflux pump
Validation Method: efflux assay and MIC testing
Drug Classes: erythromycin
Organisms: Escherichia coli KAM32, Escherichia coli BL21(DE3)
Papers: 1
Databases: Reslit

Papers1

1

Effect of membrane fusion protein AdeT1 on the antimicrobial resistance of Escherichia coli.

PMID 33235243 · 2020

Wild-type AdeT1 does not confer antimicrobial resistance in E. coli, but propionylation of Lys280 on AdeT1 increases resistance to erythromycin.

Gene Information

Gene Name: adeT1
Allele: adeT1
Encodes: membrane fusion protein
Source Database: Reslit
Mechanism: forms an active efflux pump
Confers Resistance To: erythromycin
Organisms Tested In: • Escherichia coli KAM32
• Escherichia coli BL21(DE3)
Validation Method: efflux assay and MIC testing

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research