Browse AMR Genes

Explore antimicrobial resistance genes from the literature

adhE

acetaldehyde/alcohol dehydrogenase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to adhE

Browse AMR rules for adhE

Overview

Drug Classes: phenicols
Organisms: Escherichia coli
Papers: 1
Mutations: 4

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
A392V	-	-	Escherichia coli	phenicols	Reslit	Candidate
F583L	-	-	Escherichia coli	phenicols	Reslit	Candidate
A626V	-	-	Escherichia coli	phenicols	Reslit	Candidate
A626T	-	-	Escherichia coli	phenicols	Reslit	Candidate

Papers1

1

Evolutionary Changes after Translational Challenges Imposed by Horizontal Gene Transfer.

PMID 30753446 · 2019

adhE was mutated in all populations selected in presence of chloramphenicol.

Mutation Information

adhE: p.A392V adhE: p.F583L adhE: p.A626V adhE: p.A626T

Protein Change: A392V, F583L, A626V, A626T
Organisms: Escherichia coli
Confers Resistance To: phenicols
Validation Method: whole genome sequencing
Source Database: Reslit