Browse AMR Genes

Explore antimicrobial resistance genes from the literature

algU

sigma factor

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to algU

Browse AMR rules for algU

Overview

Drug Classes: tobramycin, imipenem
Organisms: Pseudomonas aeruginosa
Papers: 2
Mutations: 2

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
R174L	-	-	Pseudomonas aeruginosa	tobramycin	Reslit	Candidate
-	PA5001ins	-	Pseudomonas aeruginosa	imipenem	Reslit	Candidate

Papers2

1

The Effects of Sub-inhibitory Antibiotic Concentrations on Pseudomonas aeruginosa: Reduced Susceptibility Due to Mutations.

PMID 34987489 · 2021

Mutation Information

Protein Change: R174L
Organisms: Pseudomonas aeruginosa
Confers Resistance To: tobramycin
Validation Method: whole-genome sequencing
Source Database: Reslit

2

Genetic determinants involved in the susceptibility of Pseudomonas aeruginosa to beta-lactam antibiotics.

PMID 20679510 · 2010

mutation in promoter region

Mutation Information

algU: c.PA5001ins

Nucleotide Change: PA5001ins
Organisms: Pseudomonas aeruginosa
Confers Resistance To: imipenem
Validation Method: complementation assay
Source Database: Reslit