Browse AMR Genes

Explore antimicrobial resistance genes from the literature

ampD1

peptidoglycan-recycling amidase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to ampD1

Browse AMR rules for ampD1

Overview

Mechanism: nonfunctional
Drug Classes: ceftazidime
Organisms: Pseudomonas aeruginosa
Papers: 1
Mutations: 1

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
G148A	-	nonfunctional	Pseudomonas aeruginosa	ceftazidime	Reslit	Candidate

Papers1

1

Role of ampD Homologs in Overproduction of AmpC in Clinical Isolates of Pseudomonas aeruginosa.

PMID 18779353 · 2008

Mutations in ampD1 lead to nonfunctional AmpD proteins and ceftazidime resistance.

Mutation Information

Protein Change: G148A
Organisms: Pseudomonas aeruginosa
Confers Resistance To: ceftazidime
Effect on Function: nonfunctional
Validation Method: plasmid model system
Source Database: Reslit