Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
multidrug efflux MFS transporter AmvA
Overview
| Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|
| Q294L | - | - | Acinetobacter baumannii | colistin | Reslit | Candidate |
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| AmvA | Card DatabaseReference Gene CatalogReslit | 12 | EFFLUX, erythromycin +12 | Acinetobacter baumannii +7 | Global|India|Spain, Spain, Brazil, Egypt, India, Thailand, United States|Minnesota, China | 2010, 2011, 2012, 2013, 2016, 2021, 2022, 2025 | FJ911554.1 | ACQ82816.1 |
| Amv A | Reslit | 2 | macrolides, tetracycline +2 | Acinetobacter baumannii | South Africa, India|China|Brazil | 2022, 2025 | PRJNA765178 | - |
Molecular and functional characterization of a novel efflux pump, AmvA, mediating antimicrobial and disinfectant resistance in Acinetobacter baumannii.
Molecular and functional characterization of a novel efflux pump, AmvA, mediating antimicrobial and disinfectant resistance in Acinetobacter baumannii.
Efflux-mediated antibiotic resistance in Acinetobacter spp.
The study characterizes several efflux pumps in Acinetobacter spp., including AdeABC, AdeIJK, AdeFGH, CraA, AmvA, AbeM, AbeS, AdeXYZ, AdeDE, TetA, TetB, CmlA, FloR, and QacE, which contribute to multidrug resistance by expelling antibiotics and other compounds.
The Acinetobacter baumannii Oxymoron: Commensal Hospital Dweller Turned Pan-Drug-Resistant Menace.
The paper discusses various virulence factors and mechanisms contributing to the pathogenicity and antibiotic resistance of Acinetobacter baumannii, including biofilm formation, surface polysaccharides, and outer membrane proteins.
Contribution of efflux pumps, porins, and β-lactamases to multidrug resistance in clinical isolates of Acinetobacter baumannii.
The study identifies multiple efflux pumps, porins, and β-lactamases contributing to multidrug resistance in Acinetobacter baumannii, including adeB, adeJ, tetB, tetA(39), and aacC1, aphA1, aadB genes, along with mutations in gyrA and parC.
Fluorescence-Based Flow Sorting in Parallel with Transposon Insertion Site Sequencing Identifies Multidrug Efflux Systems in Acinetobacter baumannii.
The study identified the AdeABC, AdeIJK, and AmvA efflux systems and their regulators, AdeRS, AdeN, and AmvR, as critical for ethidium accumulation and resistance in Acinetobacter baumannii.
Endophytic Lifestyle of Global Clones of Extended-Spectrum β-Lactamase-Producing Priority Pathogens in Fresh Vegetables: a Trojan Horse Strategy Favoring Human Colonization?
The study identifies multiple AMR genes in endophytic ESBL-producing Enterobacterales isolated from fresh vegetables, highlighting their potential role in the spread of antibiotic resistance.
Deciphering Multidrug-Resistant Acinetobacter baumannii from a Pediatric Cancer Hospital in Egypt.
The study identified various AMR genes and mutations in multidrug-resistant Acinetobacter baumannii isolates from a pediatric cancer hospital in Egypt, highlighting the presence of bla NDM, bla OXA-23-like, bla OXA-51-like, and other resistance genes, along with mutations in pmrA and lptF contributing to colistin resistance.
Genotypic and Phenotypic Characterization of Novel Sequence Types of Carbapenem-Resistant Acinetobacter baumannii, With Heterogeneous Resistance Determinants and Targeted Variations in Efflux Operons.
The study identifies various AMR genes and mutations in carbapenem-resistant Acinetobacter baumannii strains, including beta-lactamases, aminoglycoside modifying enzymes, and efflux pumps, contributing to multidrug resistance.
Whole genome sequence of pan drug-resistant clinical isolate of Acinetobacter baumannii ST1890.
The study identified multiple antibiotic resistance genes in the pan-drug-resistant Acinetobacter baumannii strain VJR422, including genes encoding beta-lactamases, aminoglycoside-modifying enzymes, and efflux pumps, contributing to resistance against various antibiotic classes.
Molecular characterisation of Acinetobacter baumannii isolates from bloodstream infections in a tertiary-level hospital in South Africa.
The study identified colistin-resistant Acinetobacter baumannii isolates with resistance genes including bla OXA-23, bla NDM-1, lps B, and various efflux pumps. These isolates exhibited extensive drug resistance (XDR) and were associated with sequence types ST1 and ST2.
Proximity-Ligation Metagenomic Sequence Analysis Reveals That the Antibiotic Resistome Makes Significant Transitions During Municipal Wastewater Treatment.
The study reveals significant transitions in the antibiotic resistome during municipal wastewater treatment, highlighting the presence of various ARGs in untreated wastewater and their reduced abundance in treated samples. Notably, certain ARGs like blaOXA, mef(A), and msr(D) were prevalent in untreated wastewater, while others like aph(3")-Ib, aph(6)-Id, mef(C), mph(A), and mph(G) were more prominent in activated sludge samples.
Orthopedic infections associated with distinct Acinetobacter strains in rural area of Qingdao, China.
The study identified multiple AMR genes in Acinetobacter isolates, including blaOXA-23, blaOXA-66, blaOXA-213, blaADC-6, mcr-4.3, amvA, and rsmA, highlighting the diversity of resistance mechanisms in different species.
Comparative genomics reveals avian Acinetobacter baumannii as antimicrobial resistance reservoirs and bovine strains with elevated pathogenicity.
Avian Acinetobacter baumannii strains were found to carry a significantly higher number of antimicrobial resistance genes compared to bovine and porcine strains, highlighting their potential role in the dissemination of antimicrobial resistance through animal origin foods.
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