Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
ANT(6)
Overview
Aminoglycoside-streptothricin resistance gene cluster aadE-sat4-aphA-3 disseminated among multiresistant isolates of Enterococcus faecium.
Aminoglycoside-streptothricin resistance gene cluster aadE-sat4-aphA-3 disseminated among multiresistant isolates of Enterococcus faecium.
Aminoglycoside-streptothricin resistance gene cluster aadE-sat4-aphA-3 disseminated among multiresistant isolates of Enterococcus faecium., Presence and genetic environment of pleuromutilin-lincosamide-streptogramin A resistance gene lsa(E) in enterococci of human and swine origin., pEOC01: a plasmid from Pediococcus acidilactici which encodes an identical streptomycin resistance (aadE) gene to that found in Campylobacter jejuni., Pheromone-responsive conjugative vancomycin resistance plasmids in Enterococcus faecalis isolates from humans and chicken feces.
Pheromone-responsive conjugative vancomycin resistance plasmids in Enterococcus faecalis isolates from humans and chicken feces.
The study identifies vancomycin resistance plasmids pSL1 and pSL2 in Enterococcus faecalis isolates from humans and chicken feces, which carry multiple resistance genes including vanA, ermB, aph(3')-IIIa, ant(6')-Ia, and aac(6')-aph(2').
Pheromone-responsive conjugative vancomycin resistance plasmids in Enterococcus faecalis isolates from humans and chicken feces.
Pheromone-responsive conjugative vancomycin resistance plasmids in Enterococcus faecalis isolates from humans and chicken feces.
Characterization of new staphylococcal cassette chromosome mec (SCCmec) and topoisomerase genes in fluoroquinolone- and methicillin-resistant Staphylococcus pseudintermedius.
The study characterizes new SCCmec elements and mutations in topoisomerase genes associated with fluoroquinolone and methicillin resistance in Staphylococcus pseudintermedius.
Rapid evolution of virulence and drug resistance in the emerging zoonotic pathogen Streptococcus suis.
Rapid evolution of virulence and drug resistance in the emerging zoonotic pathogen Streptococcus suis.
Rapid evolution of virulence and drug resistance in the emerging zoonotic pathogen Streptococcus suis.
The genome of Streptococcus mitis B6--what is a commensal?
Aminoglycoside modifying enzymes.
The paper discusses various aminoglycoside modifying enzymes, particularly focusing on AAC(6')-Ib, AAC(6')-Ib-cr, and AAC(6')-Ib 11, which confer resistance to aminoglycosides like amikacin and gentamicin, and in some cases, quinolones.
Novel pseudo-staphylococcal cassette chromosome mec element (ψSCCmec57395) in methicillin-resistant Staphylococcus pseudintermedius CC45.
The study identifies a novel pseudo-staphylococcal cassette chromosome mec element (ψSCCmec57395) in methicillin-resistant Staphylococcus pseudintermedius CC45, along with various AMR genes such as mecA, blaZ, aac(6')-Ie–aph(2')-Ia, aph(3')-III, ant(6)-Ia, sat4, erm(B), tet(M), dfr(G), and cat pC221. Additionally, fluoroquinolone resistance was linked to specific mutations in gyrA and grlA.
Drug-resistant and hospital-associated Enterococcus faecium from wastewater, riverine estuary and anthropogenically impacted marine catchment basin.
The study identified multiple AMR genes in Enterococcus faecium isolates from wastewater, marine outfalls, and river environments, including pbp5, aac(6')-Ie-aph(2"), ant(6')-Ia, tet(M), and tet(L). Mutations in gyrA (S84R) were associated with ciprofloxacin resistance.
Unraveling antimicrobial resistance genes and phenotype patterns among Enterococcus faecalis isolated from retail chicken products in Japan.
The study identified several antimicrobial resistance genes in Enterococcus faecalis isolated from retail chicken products in Japan, including aac(6')-Ie-aph(2")-Ia, aph(3')-IIIa, ant(6)-Ia, tet(L), tet(M), tet(O), and erm(B). These genes were associated with resistance to various antibiotics such as kanamycin, gentamicin, streptomycin, dihydrostreptomycin, oxytetracycline, and erythromycin.
Detection of antibiotic resistance in probiotics of dietary supplements.
The study detected antibiotic resistance in probiotic bacteria from dietary supplements, including resistance to streptomycin, gentamycin, aztreonam, and ciprofloxacin. Intrinsic resistance genes such as aac(6')-aph(2"), ant(6), aph(3')-IIIa, and blaZ were identified as potential contributors to the observed resistance profiles.
Demography and Intercontinental Spread of the USA300 Community-Acquired Methicillin-Resistant Staphylococcus aureus Lineage.
The study characterizes the AMR genes and mutations in the USA300 CA-MRSA lineage, highlighting the presence of multiple resistance determinants including beta-lactam, aminoglycoside, macrolide, and fluoroquinolone resistance genes, as well as specific mutations in gyrA and parC contributing to fluoroquinolone resistance.
Identification of source and sink populations for the emergence and global spread of the East-Asia clone of community-associated MRSA.
The study identifies distinct antibiotic resistance gene profiles in Staphylococcus aureus ST59 isolates from the USA and East Asia, with the East Asia clade exhibiting higher resistance to beta-lactams, chloramphenicol, tetracyclines, and macrolides.
Genomic Analysis Reveals Multi-Drug Resistance Clusters in Group B Streptococcus CC17 Hypervirulent Isolates Causing Neonatal Invasive Disease in Southern Mainland China.
The study identifies multiple antibiotic resistance genes, including tetO, ermB, ant6, aphA, ant9, and lnuB, in Group B Streptococcus CC17 isolates from China, highlighting the emergence of multi-drug resistance in these hypervirulent strains.
Comparative genomics of Clostridium bolteae and Clostridium clostridioforme reveals species-specific genomic properties and numerous putative antibiotic resistance determinants.
The study identified numerous antibiotic resistance genes in Clostridium bolteae and Clostridium clostridioforme, including beta-lactamases, glycopeptide resistance operons, macrolide and lincosamide resistance genes, and efflux pumps. Notably, C. bolteae 90B3 exhibited resistance to linezolid, chloramphenicol, florfenicol, and tiamulin due to the presence of the 23S rRNA methyltransferase gene cfr. Additionally, C. clostridioforme 90A8 possessed a VanB-type operon conferring vancomycin resistance.
Assessment of antibiotic susceptibility in Lactobacillus isolates from chickens.
The study identified several tetracycline, macrolide, and aminoglycoside resistance genes in Lactobacillus isolates from chickens, highlighting the presence of resistance mechanisms in these bacteria.
ICESag37, a Novel Integrative and Conjugative Element Carrying Antimicrobial Resistance Genes and Potential Virulence Factors in Streptococcus agalactiae.
The study characterizes ICE Sag37, a novel integrative and conjugative element carrying multiple antimicrobial resistance genes, including erm(B), tet(O), aadE, aphA, and ant(6), in Streptococcus agalactiae.
Genomic comparisons of Streptococcus suis serotype 9 strains recovered from diseased pigs in Spain and Canada.
The study identified multiple tetracycline, macrolide, lincosamide, and aminoglycoside resistance genes in Streptococcus suis serotype 9 strains, highlighting the widespread presence of antibiotic resistance mechanisms in these isolates.
Whole-Genome Sequence Analysis of Multidrug-Resistant Campylobacter Isolates: a Focus on Aminoglycoside Resistance Determinants.
The study identified two new aminoglycoside phosphotransferase genes (aph(2")-Ii1 and aph(2")-Ii2) associated with gentamicin resistance, a lincosamide nucleotidyltransferase gene (lnu(G)) linked to lincomycin resistance, and new resistance enzymes (apmA and spw) potentially conferring resistance to spectinomycin and gentamicin. Additionally, ant(6)-Ig and ant(6)-If were found to be associated with streptomycin resistance, while ant(9)-Ic was linked to spectinomycin resistance.
Whole-Genome Sequence Analysis of Multidrug-Resistant Campylobacter Isolates: a Focus on Aminoglycoside Resistance Determinants.
The study identified two new aminoglycoside phosphotransferase genes (aph(2")-Ii1 and aph(2")-Ii2) associated with gentamicin resistance, a lincosamide nucleotidyltransferase gene (lnu(G)) linked to lincomycin resistance, and new resistance enzymes (apmA and spw) potentially conferring resistance to spectinomycin and gentamicin. Additionally, ant(6)-Ig and ant(6)-If were found to be associated with streptomycin resistance, while ant(9)-Ic was linked to spectinomycin resistance.
Safety and Growth Optimization of Lactic Acid Bacteria Isolated From Feedlot Cattle for Probiotic Formula Design.
The study identified several AMR genes in feedlot lactobacilli, including ermB, tet(S), aadA, ant(6), bla, and aph(3''-III), which confer resistance to erythromycin, tetracycline, streptomycin, kanamycin, and ampicillin. These genes were detected through PCR analysis and correlate with phenotypic resistance in some strains.
Antimicrobial Resistance in Lactobacillus Species: A Genomic and Phenotypic Analysis
The study identifies various tetracycline, erythromycin, chloramphenicol, and aminoglycoside resistance genes in Lactobacillus species, highlighting their potential role in antimicrobial resistance and horizontal gene transfer.
Identification and antibiotic susceptibility of lactobacilli isolated from turkeys.
The study identified several tetracycline, macrolide, and lincosamide resistance genes in turkey-derived lactobacilli, including tetL, tetM, tetW, ermB, ermC, lnuA, aadE, ant(6)-Ia, cat, and lsaE. These genes were associated with resistance to tetracycline, erythromycin, lincomycin, streptomycin, chloramphenicol, and tiamulin.
ant(6)-I Genes Encoding Aminoglycoside O-Nucleotidyltransferases Are Widely Spread Among Streptomycin Resistant Strains of Campylobacter jejuni and Campylobacter coli.
The study identifies ant(6)-Ie as a novel aminoglycoside O-nucleotidyltransferase gene contributing to streptomycin resistance in Campylobacter coli, while ant(6)-Ie in C. jejuni is non-functional due to truncation.
Pilot Safety Evaluation of a Novel Strain of Bacteroides ovatus.
The study identified several antibiotic resistance genes in Bacteroides ovatus ELH-B2, including those conferring resistance to tetracycline, erythromycin, aminoglycosides, macrolides, and other antibiotics. These genes were validated through minimum inhibitory concentration (MIC) tests.
Molecular characteristics and comparative genomics analysis of a clinical Enterococcus casseliflavus with a resistance plasmid.
The study identified six resistance genes (aph3', ant6, bla, sat4, and two ermB) on the plasmid pEC369, along with a vanC-2 gene cluster on the chromosome, contributing to resistance against erythromycin, kanamycin, streptomycin, and vancomycin in Enterococcus casseliflavus EC369.
Draft Genome Sequence of an Enterococcus faecalis Strain (24FS) That Was Isolated from Healthy Infant Feces and Exhibits High Antibacterial Activity, Multiple-Antibiotic Resistance, and Multiple Virulence Factors.
The study reports the draft genome sequence of Enterococcus faecalis 24FS, highlighting its multiple-antibiotic resistance traits, including resistance to chloramphenicol, tetracycline, erythromycin, aminoglycosides, fluoroquinolones, trimethoprim, streptothricin, and streptomycin, along with potential virulence factors.
Emergence of multidrug resistance and extensive drug resistance among enterococcal clinical isolates in Egypt.
The study identified several AMR genes in enterococcal isolates, including aac(6')-Ie-aph(2'')-Ia, ant(6')-Ia, ermB, msrA/B, tetK, tetL, tetM, vanB, vanC1, and optrA, which confer resistance to various antibiotics such as gentamicin, streptomycin, macrolides, lincosamides, tetracyclines, vancomycin, and linezolid.
Identification and molecular epidemiology of methicillin resistant Staphylococcus pseudintermedius strains isolated from canine clinical samples in Argentina.
The study identified various AMR genes in methicillin-resistant Staphylococcus pseudintermedius (MRSP) isolates from Argentina, including mecA, blaZ, ermB, dfrG, aph(3')-III, ant(6)-Ia, tetM, and aac(6')-Ie-aph(2')-Ia. Mutations in gyrA (S84L) and grlA (S80I) were associated with ciprofloxacin resistance.
Comparative diversity of microbiomes and Resistomes in beef feedlots, downstream environments and urban sewage influent.
The study identified several tetracycline, macrolide, aminoglycoside, beta-lactam, sulfonamide, mercury, and biocide resistance genes in beef feedlots, catch basin water, soil, and urban sewage influent. Tetracycline resistance was predominant in beef production systems, while urban sewage influent showed a diverse resistome with resistance to multiple antimicrobial classes.
High incidence of virulence determinants, aminoglycoside and vancomycin resistance in enterococci isolated from hospitalized patients in Northwest Iran.
The study identified several aminoglycoside resistance genes (aac(6')-Ie-aph(2")-Ia, ant(3")-III, aph(3')-IIIa, ant(6')-Ia) and the vancomycin resistance gene vanA in enterococci isolated from hospitalized patients in Northwest Iran. These genes were found to confer resistance to gentamicin and vancomycin, highlighting the prevalence of multidrug-resistant enterococci in the region.
Antimicrobial Resistance, Virulence, and Genetic Lineages of Staphylococci from Horses Destined for Human Consumption: High Detection of S. aureus Isolates of Lineage ST1640 and Those Carrying the lukPQ Gene.
The study identified antimicrobial resistance genes such as ant(6)-Ia, blaZ, dfrA, and dfrG in Staphylococcus aureus isolates, along with the equine-adapted leukocidin gene lukPQ and the complement inhibitor gene scn-eq. These findings highlight the presence of virulence and resistance determinants in S. aureus isolates from horses.
Characterization of the First mecA-Positive Multidrug-Resistant Staphylococcus pseudintermedius Isolated from an Argentinian Patient.
The study characterizes the first mecA-positive multidrug-resistant Staphylococcus pseudintermedius isolate from an Argentinean patient, identifying several AMR genes and mutations associated with resistance to multiple antibiotics.
Metagenomic analysis reveals the microbiome and resistome in migratory birds.
The study identifies numerous antibiotic resistance genes (ARGs) in migratory birds, highlighting the presence of mcr-1, beta-lactamases, tetracycline resistance genes, and other resistance mechanisms. These findings suggest that migratory birds could serve as reservoirs and potential vectors for spreading ARGs into the environment.
Surveillance of Enterococcus spp. reveals distinct species and antimicrobial resistance diversity across a One-Health continuum.
The study identified several AMR genes in Enterococcus spp., including erm(B), tet(M), optrA, dfrE, lsa(A), aac(6')-Ib, eat(A), ant(6)-Ia, aph(3')-IIIa, sat4, tet(L), bcrB, bcrC, dfrF, and dfrG, which confer resistance to various antibiotics such as macrolides, tetracyclines, oxazolidinones, trimethoprim, and aminoglycosides.
Emergence of vanA-Type Vancomycin-Resistant Enterococcus faecium ST 78 Strain with a rep2-Type Plasmid Carrying a Tn1546-Like Element Isolated from a Urinary Tract Infection in China.
The study identifies a vanA-type vancomycin-resistant Enterococcus faecium ST78 strain carrying a rep2-type plasmid with a Tn1546-like element. The strain exhibits resistance to multiple antibiotics, including vancomycin, teicoplanin, and aminoglycosides, due to the presence of the vanA, ant(6)-Ia, aph(3')-III, aac(6')-Ii, and msr(C) genes.
Antimicrobial Resistance Gene Detection and Plasmid Typing Among Multidrug Resistant Enterococci Isolated from Freshwater Environment.
The study identified twelve antimicrobial resistance genes in multidrug-resistant Enterococcus isolates from freshwater, including genes conferring resistance to tetracycline, erythromycin, tylosin, kanamycin, streptomycin, and ciprofloxacin. These genes were detected through PCR and sequencing, highlighting the diversity of resistance mechanisms in environmental Enterococcus.
Prediction of antimicrobial resistance in clinical Campylobacter jejuni isolates from whole-genome sequencing data.
The study identified seven resistance genes and several mutations associated with antimicrobial resistance in Campylobacter jejuni isolates, demonstrating the effectiveness of whole-genome sequencing in predicting resistance.
Genomic Analysis Reveals the Genetic Determinants Associated With Antibiotic Resistance in the Zoonotic Pathogen Campylobacter spp. Distributed Globally.
The study identified 15 acquired genes associated with resistance to five distinct antibiotic classes in Campylobacter spp., including novel beta-lactamase genes blaOXA-493 and blaOXA-576, and characterized mutations in gyrA, rpsL, and 23S rRNA that confer resistance to fluoroquinolones, streptomycin, and macrolides, respectively.
Antimicrobial Resistance of Coagulase-Positive Staphylococcus Isolates Recovered in a Veterinary University Hospital.
The study identified various antimicrobial resistance genes in methicillin-resistant Staphylococcus pseudintermedius (MRSP) isolates, including blaZ, erm(B), erm(C), aph(3'), ant(6), aad(6), SAT-4, cat(pc221), dfr(G), tet(K), and tet(M). These genes were associated with resistance to beta-lactams, macrolides, aminoglycosides, chloramphenicol, trimethoprim, and tetracycline.
A Longitudinal Evaluation of the Bacterial Pathogens Colonizing Chronic Non-Healing Wound Sites at a United States Military Treatment Facility in the Pacific Region.
The study identified multiple antimicrobial resistance genes in bacterial isolates from chronic non-healing wounds, including beta-lactamases, aminoglycoside modifying enzymes, macrolide resistance genes, and others. These genes were found in various bacterial species such as E. coli, S. aureus, P. aeruginosa, and others.
Whole genome-based characterisation of antimicrobial resistance and genetic diversity in Campylobacter jejuni and Campylobacter coli from ruminants.
The study identified various AMR genes including aminoglycoside-modifying enzymes, tetracycline resistance genes, and beta-lactamases in Campylobacter jejuni and C. coli isolates from ruminants. Mutations in gyrA and rpsL were linked to quinolone and streptomycin resistance, respectively. The presence of specific genetic determinants correlated with phenotypic resistance.
High-throughput sequencing reveals genetic determinants associated with antibiotic resistance in Campylobacter spp. from farm-to-fork.
The study identified several AMR genes and mutations associated with resistance to quinolones, tetracyclines, and macrolides in Campylobacter isolates from various sources. Key findings include the prevalence of blaOXA-61, tet(O), and mutations in gyrA and 23S rRNA genes.
Whole Genome Analysis of Three Multi-Drug Resistant Listeria innocua and Genomic Insights Into Their Relatedness With Resistant Listeria monocytogenes.
The study identified multiple AMR genes in three multi-drug resistant L. innocua isolates, including tet(M), optrA, fexA, dfrG, lnu(B), lsa(E), ant(6)-Ia, erm(B), aph(3')-IIIa, catA8, lnu(A), msr(D), and mef(A). These genes confer resistance to various antibiotics such as tetracycline, oxazolidinones, fluoroquinolones, trimethoprim, lincomycin, macrolides, aminoglycosides, and chloramphenicol.
Environmental Surveillance and Characterization of Antibiotic Resistant Staphylococcus aureus at Coastal Beaches and Rivers on the Island of Hawai'i.
The study identified various antibiotic resistance genes in Staphylococcus aureus isolates from coastal beaches and rivers on the island of Hawai'i, highlighting the presence of multidrug-resistant strains.
Genomic and pathogenic investigations of Streptococcus suis serotype 7 population derived from a human patient and pigs.
The study identified several AMR genes in Streptococcus suis serotype 7 strains, including tetracycline resistance genes (tet(O), tet(M), tet(W)), macrolide/lincosamide/streptogramin resistance gene (erm(B)), aminoglycoside resistance genes (ant(6)-Ia, aph(3')-IIIa, aac(6')-Ie-aph(2'')-Ia), trimethoprim resistance gene (dfrF), and chloramphenicol resistance gene (cat-TC).
Genomic and pathogenic investigations of Streptococcus suis serotype 7 population derived from a human patient and pigs.
The study identified several AMR genes in Streptococcus suis serotype 7 strains, including tetracycline resistance genes (tet(O), tet(M), tet(W)), macrolide/lincosamide/streptogramin resistance gene (erm(B)), aminoglycoside resistance genes (ant(6)-Ia, aph(3')-IIIa, aac(6')-Ie-aph(2'')-Ia), trimethoprim resistance gene (dfrF), and chloramphenicol resistance gene (cat-TC).
The Integrative and Conjugative Element ICECspPOL2 Contributes to the Outbreak of Multi-Antibiotic-Resistant Bacteria for Chryseobacterium Spp. and Elizabethkingia Spp.
The study identifies the integrative and conjugative element ICE Csp POL2 in the multi-antibiotic-resistant strain Chryseobacterium sp. POL2, which carries several antibiotic resistance genes including those conferring resistance to carbapenems, chloramphenicol, florfenicol, macrolides, tetracycline, and aminoglycosides. The element was found to transfer horizontally to Elizabethkingia species, contributing to the spread of multiple antibiotic resistance genes.
Emerging Fatal Ib/CC12 Hypervirulent Multiresistant Streptococcus agalactiae in Young Infants With Bloodstream Infection in China.
The study identifies multiple antibiotic resistance genes in Ib/CC12 Streptococcus agalactiae strains, including genes conferring resistance to macrolides, clindamycin, aminoglycosides, tetracycline, and other antibiotics.
Whole genome sequence analyses-based assessment of virulence potential and antimicrobial susceptibilities and resistance of Enterococcus faecium strains isolated from commercial swine and cattle probiotic products.
The study identified several antimicrobial resistance (AMR) genes in Enterococcus faecium strains isolated from commercial swine and cattle probiotics, including aac(6')-Ii, aph(3')-III, ant(6)-Ia, tet(L), tet(M), msrC, and cat-(pc194). These genes confer resistance to aminoglycosides, tetracyclines, macrolides, lincosamides, streptogramin B, and phenicols.
Comparing Long-Read Assemblers to Explore the Potential of a Sustainable Low-Cost, Low-Infrastructure Approach to Sequence Antimicrobial Resistant Bacteria With Oxford Nanopore Sequencing.
The study identifies the presence of the bla KPC gene in Klebsiella pneumoniae isolates using long-read sequencing, highlighting its role in carbapenem resistance.
Antimicrobial resistance determinants in silage.
The study identified 16 antimicrobial resistance genes (ARGs) in silage samples, highlighting their potential to spread through the food chain and contribute to antimicrobial resistance.
Drinking water chlorination has minor effects on the intestinal flora and resistomes of Bangladeshi children.
The study identified several antibiotic resistance genes (ARGs) in the gut microbiome of Bangladeshi children, including bla CTX-M, mph(A), qnrS1, mdf(A), tet(A), sul2, aadA5, tet(X), erm(X), nimE, dfrA17, bla TEM, and ant(6’)-Ia. These genes were associated with resistance to various antibiotics such as third-generation cephalosporins, azithromycin, fluoroquinolones, tetracyclines, sulfonamides, streptomycin, spectinomycin, macrolides, lincosamides, streptogramin B, nitroimidazoles, trimethoprim, penicillins, and aminoglycosides.
Characteristics of Streptococcus agalactiae Colonizing Nonpregnant Adults Support the Opportunistic Nature of Invasive Infections.
The study identified ermA, ermB, and mefE genes associated with macrolide resistance in Streptococcus agalactiae isolates from nonpregnant adults, along with tetM for tetracycline resistance and aph(3')-IIIa and ant(6)-Ia for streptomycin resistance.
Prior exposure to microcystin alters host gut resistome and is associated with dysregulated immune homeostasis in translatable mouse models.
The study identifies that prior exposure to microcystin-LR alters the gut resistome, increasing the abundance of antibiotic resistance genes such as mefA, msrD, mel, tet40, and ant6, which are associated with resistance to macrolides, tetracycline, and aminoglycosides.
Genomic Insights of Enterococcus faecium UC7251, a Multi-Drug Resistant Strain From Ready-to-Eat Food, Highlight the Risk of Antimicrobial Resistance in the Food Chain.
The study identifies multiple antimicrobial resistance genes in Enterococcus faecium UC7251, including aac(6')-Ia, ermB, tetM, tetL, pbp5, aad6, aadE, aph(3')-III, ant(6')-Ia, satA, lnuB, and isaE, highlighting the risk of antimicrobial resistance in the food chain.
Genomic Characterization of Enterococcus hirae From Beef Cattle Feedlots and Associated Environmental Continuum.
The study identified several AMR genes in Enterococcus hirae isolates from beef cattle feedlots, including tetracycline resistance genes (tet(L), tet(M), tet(O), tet(S/M), tet(O/32/O)), macrolide resistance gene erm(B), and aminoglycoside resistance genes (aac(6')-Iid, ant(6)-Ia, aph(3')-III, sat4).
Genomic diversity of genus Limosilactobacillus.
The study identified 18 AMR genes in Limosilactobacillus species, primarily in L. reuteri from animal sources, including tetracycline, aminoglycoside, macrolide-lincosamide-streptogramin, and lincomycin resistance genes.
Antimicrobial-Resistant Enterococcus spp. in Wild Avifauna from Central Italy.
The study identified aac(6')-Ie-aph(2")-Ia, ant(6')-Ia, and tet(M) as key genes contributing to aminoglycoside and tetracycline resistance in Enterococcus spp. isolated from wild birds.
Exploring the mobilome and resistome of Enterococcus faecium in a One Health context across two continents.
The study identifies various AMR genes in Enterococcus faecium, including vanA, vanB, ermB, ermT, ermA, aad(6), aph(3')-IIIa, aac(6')-Ie-aph(2')-Ia, sat-4, tetM, tet(W/N/W), dfrG, dfrF, lnuB, optrA, and lsaE, which are associated with different habitats and geographic locations.
Balancing the Virulence and Antimicrobial Resistance in VISA DAP-R CA-MRSA Superbug.
The study identifies several AMR genes, including ant(6)-Ia, aph(3')-III, blaZ, mecA, ermC, and tetK, which contribute to resistance against aminoglycosides, beta-lactams, macrolides, and tetracyclines in VISA DAP-R CA-MRSA. Additionally, a mutation in mprF (Thr345Ala) is linked to daptomycin and glycopeptide resistance.
Longitudinal Analysis of Antimicrobial Resistance among Enterococcus Species Isolated from Australian Beef Cattle Faeces at Feedlot Entry and Exit.
Genetic diversity and variation in antimicrobial-resistance determinants of non-serotype 2 Streptococcus suis isolates from healthy pigs.
The study identified 18 AMR genes in non-serotype 2 Streptococcus suis isolates from healthy pigs, including genes conferring resistance to aminoglycosides, macrolides, lincosamides, tetracyclines, oxazolidinones, nucleosides, and phenicols.
Detection and Genomic Characterisation of Clostridioides difficile from Spinach Fields.
The study identified various antimicrobial resistance genes in C. difficile isolates from spinach and soil samples, including vanB, tet(M), ant(6)-Ia, qacG, cdeA, SAT-4, vanXY, vanR, D19aph(3')-III_1, tet(40), and CDD-1, indicating resistance to vancomycin, tetracyclines, aminoglycosides, disinfectants, fluoroquinolones, nucleosides, and beta-lactams.
Detection and Genomic Characterisation of Clostridioides difficile from Spinach Fields.
The study identified various antimicrobial resistance genes in C. difficile isolates from spinach and soil samples, including vanB, tet(M), ant(6)-Ia, qacG, cdeA, SAT-4, vanXY, vanR, D19aph(3')-III_1, tet(40), and CDD-1, indicating resistance to vancomycin, tetracyclines, aminoglycosides, disinfectants, fluoroquinolones, nucleosides, and beta-lactams.
How Streptococcus suis escapes antibiotic treatments.
The study characterizes various AMR genes and mutations in Streptococcus suis, highlighting resistance to beta-lactams, macrolides, lincosamides, streptogramins, amphenicols, pleuromutilins, tetracyclines, sulfonamides, trimethoprim, and fluoroquinolones.
Distribution Patterns of Antibiotic Resistance Genes and Their Bacterial Hosts in a Manure Lagoon of a Large-Scale Swine Finishing Facility.
The study identified multiple antibiotic resistance genes (ARGs) in manure samples from a swine finishing facility, highlighting the prevalence of resistance to tetracyclines, macrolides, aminoglycosides, and other antibiotics. Key genes included tet(M), lnuA, erm(35), aadS, mphB, dfrG, vga-type ABC-F, lsa-type ABC-F, msr-type ABC-F, optrA, and others, primarily found in Firmicutes, Proteobacteria, and Bacteroidota. These genes were associated with resistance mechanisms such as target alteration, antibiotic inactivation, and efflux pumps.
Comparative virulence and antimicrobial resistance distribution of Streptococcus suis isolates obtained from the United States.
The study identified several antimicrobial resistance (AMR) genes in Streptococcus suis isolates from the United States, including ble, tetO, ermB, lsaE, lnuB, ant(9)-Ia, and ant(6)-Ia, which confer resistance to glycopeptides, tetracyclines, macrolide-lincosamide-streptogramin B, pleuromutilins, and aminoglycosides respectively.
Association of CRISPR-Cas System with the Antibiotic Resistance and Virulence Genes in Nosocomial Isolates of Enterococcus.
The study found that the CRISPR-Cas system is associated with reduced antibiotic resistance and virulence in Enterococcus isolates. Specific resistance genes such as ermB, aadE, ant(6), aac(6')-aph(2"), tetM, and vanA were identified in the isolates.
Clonal Complex 12 Serotype Ib Streptococcus agalactiae Strain Causing Complicated Sepsis in Neonates: Clinical Features and Genetic Characteristics.
The study identifies the presence of the integrative and conjugative element ICE Sag37 in type Ib ST12 GBS isolates, which carries multiple antibiotic resistance genes such as erm(B), tet(O), aadE, aphA, ant-6, lsa(E), and lun(B), contributing to high resistance rates to erythromycin and clindamycin. Additionally, the virulence gene pezT was found in these isolates.
Genetic characteristics, antimicrobial resistance, and prevalence of Arcobacter spp. isolated from various sources in Shenzhen, China.
The study identified several AMR genes in Arcobacter spp., including beta-lactamase genes (blaOXA464, blaOXA491), tetracycline resistance genes (tet(L), tet(H), tet(M)), a macrolide resistance gene (ere(A)), and aminoglycoside resistance genes (APH(3')-IIIa, ant(6)-Ia, SAT-4). Additionally, a mutation in the gyrA gene (C254T) was found to confer fluoroquinolone resistance.
Dissemination and characteristics of high-level erythromycin-resistant Enterococcus faecalis from bulk tank milk of dairy companies in Korea.
The study identified several AMR genes, including ermB, tetM, tetL, optrA, aac(6')-Ie-aph(2'')-la, ant(6')-Ia, and Int-Tn, in high-level erythromycin-resistant Enterococcus faecalis isolates from bulk tank milk in Korea.
Whole-Genome and Plasmid Comparative Analysis of Campylobacter jejuni from Human Patients in Toyama, Japan, from 2015 to 2019.
The study identified tetracycline resistance gene tet(O), aminoglycoside resistance genes ant(6)-Ia and aph(3')-III, and chloramphenicol resistance gene cat in Campylobacter jejuni isolates from Toyama, Japan. Additionally, blaOXA-184 was found in ampicillin-resistant isolates.
Farming Practice Influences Antimicrobial Resistance Burden of Non-Aureus Staphylococci in Pig Husbandries.
The study found that organic and alternative pig farming practices are associated with reduced antimicrobial resistance (AMR) in non-aureus staphylococci (NAS) compared to conventional farming. Specific AMR genes such as mecA, blaZ, blaPC1, and others were more prevalent in conventional farms, while organic farms showed lower levels of AMR genes for aminoglycosides, phenicols, and tetracyclines.
Genomic insights into antibiotic resistance and mobilome of lactic acid bacteria and bifidobacteria.
The study identified several acquired and intrinsic antimicrobial resistance genes in lactic acid bacteria and bifidobacteria, including tetW, ANT(6)-Ia, aac(6')-Ie-APH(2'')-Ia, erm(B), erm(49), cat, dfrG, arr-4, and fosXCC. Additionally, mutations in S12, rsmG, Lsa(A), MsrC, and PBP5 were associated with resistance to various antibiotics.
Metagenomic analysis reveals patterns and hosts of antibiotic resistance in different pig farms.
The study identified various antibiotic resistance genes (ARGs) in pig manure samples from different regions of Shanxi, China, highlighting the prevalence of tetracycline, aminoglycoside, macrolide, and phenicol resistance genes. Key ARGs included tet(W), tet(40), tet(Q), erm(B), erm(F), mef(A), aph(3')-III, ant(6)-Ia, cfr(C), floR, blaACI-1, optrA, cat, cfxA4, cfxA5, blaCTX-M-105, blaCTX-M-65, fexB, erm(T), mdf(A), and ole(B).
Longitudinal study of the short- and long-term effects of hospitalisation and oral trimethoprim-sulfadiazine administration on the equine faecal microbiome and resistome.
Oral trimethoprim-sulfadiazine (TMS) administration leads to a significant and long-lasting increase in the relative abundance of resistance genes sul2, tetQ, ant6-1a, aph(3"-lb, and lnuC in the equine faecal microbiome.
Genomic Analysis of Vancomycin-Resistant Staphylococcus aureus Isolates from the 3rd Case Identified in the United States Reveals Chromosomal Integration of the vanA Locus.
The study identifies the chromosomal integration of the vanA locus in vancomycin-resistant Staphylococcus aureus (VRSA) isolates, highlighting the role of plasmid pWC79 in multidrug resistance and the genetic mechanisms behind the emergence of VRSA.
Enterococcal Linear Plasmids Adapt to Enterococcus faecium and Spread within Multidrug-Resistant Clades.
The study identifies pELF1-like plasmids in Enterococcus faecium that carry multiple antimicrobial resistance genes, including vancomycin resistance determinants, aminoglycoside resistance genes, macrolide resistance genes, tetracycline resistance genes, and oxazolidinone resistance genes. These plasmids are associated with multidrug-resistant clades and demonstrate high stability and self-transmissibility.
A survey on antimicrobial resistance genes of frequently used probiotic bacteria, 1901 to 2022.
The study identified various antimicrobial resistance genes in probiotic bacteria, highlighting the presence of mobile genetic elements and the potential for horizontal gene transfer.
Novel Antibiotic Resistance Genes Identified by Functional Gene Library Screening in Stenotrophomonas maltophilia and Chryseobacterium spp. Bacteria of Soil Origin.
The study identified novel variants of aminoglycoside and beta-lactam resistance genes, including aph(3')-IIc, aph(6), ant(6), IND-17, and CHM, which confer resistance to kanamycin, streptomycin, and various beta-lactam antibiotics.
Epidemiological and genomic analyses of human isolates of Streptococcus suis between 2005 and 2021 in Shenzhen, China.
The study identified multiple antimicrobial resistance genes in human isolates of Streptococcus suis, including ant(6)-Ia, tet(O), and erm(B), which confer resistance to streptomycin, tetracycline, and erythromycin/clindamycin respectively.
Antimicrobial resistance in bacteria isolated from peridomestic Rattus species: A scoping literature review.
This scoping review identifies various antimicrobial resistance (AMR) genes in bacteria isolated from peridomestic Rattus species, including beta-lactamases (bla TEM, bla CTX-M, bla SHV, bla VIM, bla IMP, bla NDM-1), aminoglycoside resistance genes (strA, strB, aadA, aphA), sulfonamide resistance genes (sul1, sul2, sul3), tetracycline resistance genes (tetA, tetB, tet34), trimethoprim resistance genes (dfrA1, dfrA17, dfr14), quinolone resistance genes (qnrB1), and others.
Analysis of Antibiotic-Resistant and Virulence Genes of Enterococcus Detected in Calf Colostrum-One Health Perspective.
The study identified multiple antibiotic-resistant genes in Enterococcus isolates from bovine colostrum, including tet(K), tet(L), tet(M), erm(B), and ant(6)-Ia, which confer resistance to tetracycline, erythromycin, and streptomycin. High rates of multidrug resistance were observed.
Inter-species diversity and functional genomic analyses of closed genome assemblies of clinically isolated, megaplasmid-containing Enterococcus raffinosus Er676 and ATCC49464.
The study characterizes antimicrobial resistance genes in Enterococcus raffinosus strains Er676 and ATCC49464, identifying genes such as tetM, ant(9)-Ia, ant(6)-Ia, ermA, efrA, efrB, optrA, and fexA, which confer resistance to tetracyclines, aminoglycosides, macrolides, oxazolidinones, and phenicols.
Whole-genome sequencing reveals changes in genomic diversity and distinctive repertoires of T3SS and T6SS effector candidates in Chilean clinical Campylobacter strains.
The study identified a high genetic diversity among C. jejuni strains and detected mutations in the gyrA gene associated with fluoroquinolone resistance. No macrolide-resistance determinants were found, but tetracycline resistance genes (tetO) and beta-lactamase genes (blaOXA-61, blaOXA-193, blaOXA-450, blaOXA-605) were prevalent. Aminoglycoside resistance genes (aph(2")-If, aac(6')-Im, ant(6)-Ia) and multidrug efflux pump genes (cmeABC) were also detected in a multi-resistant strain.
Characterization of a Tigecycline-, Linezolid- and Vancomycin-Resistant Clinical Enteroccoccus faecium Isolate, Carrying vanA and vanB Genes.
The study identifies the presence of vanA and vanB genes, along with poxtA, fexB, tet(M), and tet(L) in a multidrug-resistant Enterococcus faecium isolate, highlighting the coexistence of multiple resistance mechanisms.
Characterization of a Tigecycline-, Linezolid- and Vancomycin-Resistant Clinical Enteroccoccus faecium Isolate, Carrying vanA and vanB Genes.
The study identifies the presence of vanA and vanB genes, along with poxtA, fexB, tet(M), and tet(L) in a multidrug-resistant Enterococcus faecium isolate, highlighting the coexistence of multiple resistance mechanisms.
Clostridioides difficile from Fecally Contaminated Environmental Sources: Resistance and Genetic Relatedness from a Molecular Epidemiological Perspective.
The study identified multiple AMR genes in C. difficile isolates from environmental sources, including gyrA, gyrB, blaCDD-1, blaCDD-2, tet(M), tet(40), aph(3')-IIIa, ant(6)-la, sat-4, and ermB, which confer resistance to fluoroquinolones, beta-lactams, tetracyclines, aminoglycosides, and MLS B antibiotics.
Antimicrobial resistance and whole genome sequencing of novel sequence types of Enterococcus faecalis, Enterococcus faecium, and Enterococcus durans isolated from livestock.
The study identifies several antimicrobial resistance genes in Enterococcus species isolated from livestock in South Africa, highlighting the presence of multidrug-resistant strains and emphasizing the need for genomic surveillance to monitor the spread of antimicrobial resistance in food chain animals.
Investigation of antimicrobial susceptibility and genetic diversity among Staphylococcus pseudintermedius isolated from dogs in Rio de Janeiro.
The study identified 21 resistance determinants in MRSP and MSSP strains of Staphylococcus pseudintermedius, including genes such as blaZ, sdrM, norA, fosB, ykkcd, sepA, aac(6')-aph(2''), dfrG, aph(3')-III, ant(6)-Ia, sat4, erm(B), aad(6), tet(M), cat(pC221), qacG, tet(K), and qacJ, which confer resistance to various antimicrobials.
Canine Staphylococcaceae circulating in a Kenyan animal shelter.
The study identified various AMR genes in Staphylococcaceae strains isolated from dogs in a Kenyan animal shelter, including tetracycline, beta-lactam, and aminoglycoside resistance genes.
Effects of Neolamarckia cadamba leaves extract on microbial community and antibiotic resistance genes in cecal contents and feces of broilers challenged with lipopolysaccharides.
The study found that Neolamarckia cadamba leaves extract (NCLE) reduced the abundance of antibiotic resistance genes (ARGs) in cecal contents of lipopolysaccharide (LPS)-induced broilers by maintaining microbial balance.
Short-duration selective decontamination of the digestive tract infection control does not contribute to increased antimicrobial resistance burden in a pilot cluster randomised trial (the ARCTIC Study).
The study found no significant increase in clinically relevant antimicrobial resistance gene burden in critically ill children treated with SDD-enhanced infection control compared to standard care.
Gut diversity and the resistome as biomarkers of febrile neutropenia outcome in paediatric oncology patients undergoing hematopoietic stem cell transplantation.
The study identifies several antibiotic-resistance genes associated with febrile neutropenia in pediatric oncology patients undergoing hematopoietic stem cell transplantation, including msr(C), dfrG, erm(T), VanHAX, aac(6')-Ib, aph(3')-III, ant(6)-Ia, and aac(6')-Ii.
Gut diversity and the resistome as biomarkers of febrile neutropenia outcome in paediatric oncology patients undergoing hematopoietic stem cell transplantation.
The study identifies several antibiotic-resistance genes associated with febrile neutropenia in pediatric oncology patients undergoing hematopoietic stem cell transplantation, including msr(C), dfrG, erm(T), VanHAX, aac(6')-Ib, aph(3')-III, ant(6)-Ia, and aac(6')-Ii.
Antimicrobial susceptibility and resistome of Actinobacillus pleuropneumoniae in Taiwan: a next-generation sequencing analysis.
The study identified multiple antimicrobial resistance genes in Actinobacillus pleuropneumoniae isolates from Taiwan, including aminoglycoside, tetracycline, beta-lactam, macrolide, and phenicol resistance genes, highlighting the prevalence of multidrug resistance.
Streptococcus suis serotype 4: a population with the potential pathogenicity in humans and pigs.
The study identified multiple antibiotic resistance genes in Streptococcus suis serotype 4, including genes conferring resistance to tetracyclines, macrolides, lincosamides, aminoglycosides, oxazolidinones, and chloramphenicol. Prophages were identified as the primary vehicle for the dissemination of these resistance genes.
Defining the phylogenetics and resistome of the major Clostridioides difficile ribotypes circulating in Australia.
The study identifies AMR genes such as ermB, tetM, aac(6')-Ib, sat4A, ant6-Ia, and aph3-III in Clostridioides difficile strains, particularly in RT014/020. Mutations in gyrA and gyrB contribute to fluoroquinolone resistance. AMR is uncommon, with limited evidence of clonal transmission.
Integrative and Conjugative Elements and Prophage DNA as Carriers of Resistance Genes in Erysipelothrix rhusiopathiae Strains from Domestic Geese in Poland.
The study identifies the presence of resistance genes erm47 and ermB in Erysipelothrix rhusiopathiae strains from domestic geese in Poland, along with other resistance genes such as tetM, lnuB, lsaE, ant(6)-Ia, and spw. It also highlights the role of integrative and conjugative elements (ICEs) and prophage DNA in the spread of these resistance genes.
Evaluation of Antimicrobial Resistancein Clinical Isolates of Enterococcus spp. Obtained from Hospital Patients in Latvia.
The study identifies several AMR genes and mutations in Enterococcus isolates, including vanB for vancomycin resistance, lsaA, lsaE, lnuB for lincosamide resistance, tetM and tetL for tetracycline resistance, aac6'-Ii, aac6'-aph2'', aph3'-III, and ant6-Ia for aminoglycoside resistance, msrC, ermB, and ermT for macrolide resistance, and mutations in gyrA, parC, pbp5, and 23S rRNA for fluoroquinolone, penicillin, and linezolid resistance.
Genotypic characterization and antimicrobial susceptibility of human Campylobacter jejuni isolates in Southern Spain.
The study identified high resistance rates to ciprofloxacin (90.3%) and tetracycline (66.7%) in human Campylobacter jejuni isolates from southern Spain. Key resistance mechanisms included the T86I mutation in gyrA, the tet(O) gene, blaOXA-61, ant(6)-Ia, cmeABC, and the RE-cmeABC variant. These findings highlight the urgent need for improved surveillance and management strategies for Campylobacter infections.
Antimicrobial Resistance in Coagulase-Negative Staphylococci: Resistome, Mobiloome, and Relatedness
The study identifies multiple AMR genes and mutations in CoNS isolates from various hosts, highlighting the spread of multidrug resistance and the role of mobile genetic elements in the dissemination of resistance traits.
Transmission of dominant strains of Campylobacter jejuni and Campylobacter coli between farms and retail stores in Ecuador: Genetic diversity and antimicrobial resistance.
The study identified 14 resistance genes in Campylobacter jejuni and Campylobacter coli isolates, including genes conferring resistance to tetracycline, beta-lactams, and aminoglycosides. Mutations in gyrA, rplV, 23S rRNA, and rpsL were also associated with resistance to fluoroquinolones, macrolides, and aminoglycosides.
Molecular characterization of Streptococcus suis isolates recovered from diseased pigs in Europe.
The study identified high frequencies of tetracycline and macrolide resistance genes, specifically tetO and ermB, in European Streptococcus suis isolates.
The gut microbiota of wild birds undergoing rehabilitation as a reservoir of multidrug-resistant enterococci in a metropolitan area in Brazil.
The study identified multiple antimicrobial resistance genes in enterococci isolated from wild birds, including genes conferring resistance to aminoglycosides, erythromycin, tetracycline, and streptogramins.
Microbial spectrum and resistance of odontogenic abscesses - microbiological analysis using next generation sequencing.
The study identified multiple AMR genes in odontogenic abscesses using NGS, including genes conferring resistance to tetracyclines, macrolides, lincosamides, aminoglycosides, chloramphenicol, sulfonamides, penicillins, and others. Notably, Fusobacterium showed resistance to clindamycin.
The healthy human gut can take it all: vancomycin-variable, linezolid-resistant strains and specific bacteriocin-species interplay in Enterococcus spp.
The study identifies linezolid resistance genes optrA and poxtA in Enterococcus faecium and Enterococcus thailandicus isolates, along with a vancomycin-variable E. faecium strain. It also reveals the increasing prevalence of E. lactis in the healthy human gut and the complex interplay of bacteriocin gene profiles among Enterococcus species.
Characterization of integrative and conjugative elements carrying erm(B) and tet(O) resistance determinants in streptococcus uberis isolates from bovine milk in Chiba prefecture, Japan: CompArative GEne cluster analysis toolbox with ICEfinder.
The study identified and characterized integrative and conjugative elements (ICEs) carrying the erm(B) and tet(O) resistance genes in Streptococcus uberis isolates from bovine milk in Japan. These genes confer resistance to macrolides, lincosamides, streptogramin B, and tetracyclines.
Antibiotic Resistance in Mammalian Wild Game: A Meta-Analysis
The study presents a comprehensive meta-analysis of antibiotic resistance in bacteria isolated from mammalian wild game, highlighting the prevalence of various AMR genes and mutations across different bacterial species.
High-Risk VREfm Clones and Resistance Determinants in a Thai Hospital.
The study identified the vanA gene as the primary determinant of vancomycin resistance in all 29 VREfm isolates. Additional resistance genes such as aac(6')-Ii, ant(6')-Ia, erm(B), msr(C), tet(L), tet(M), aph(3')-III, aph(2'')-Ia, and inu(B) were also characterized, contributing to resistance against a variety of antibiotics.
AmrProfiler: A Comprehensive Tool for Antimicrobial Resistance Gene Detection and Analysis
AmrProfiler identifies a wide range of AMR genes and mutations across multiple bacterial species, demonstrating high accuracy and broader species coverage compared to existing tools.
Susceptibility of Lactobacillaceae Strains to Aminoglycoside Antibiotics in the Light of EFSA Guidelines.
The study identified aac(6)-Ie-aph(2)-Ia, ant(6)-Ia, and ant(4′)-Ia genes conferring resistance to aminoglycosides in Lactobacillaceae strains, along with a rpsL mutation causing streptomycin resistance.
Assessment of Factors Contributing to Infection Severity and High Levels of Drug Resistance in Clinical Enterococcus Isolates.
The study identified several AMR genes, including vanA, aac(6')-Ie-aph(2'')-Ia, aph(3')-IIIa, ant(6')-Ia, and ant(3'')-Ia, which confer resistance to vancomycin, gentamicin, and streptomycin in Enterococcus isolates. High levels of multidrug resistance and biofilm formation were also observed.
Rabbit carcasses as important vectors of multidrug-resistant Enterococcus faecalis, but not E. faecium: prevalence and molecular characterization from a study in Poland.
The study identified multiple AMR genes in Enterococcus faecalis isolates from rabbit carcasses, including aac(6')-Ie-aph(2")-Ia, ant(6)-Ia, aph(3')-IIIa, ermB, tetM, and tetL, which were consistent with the observed phenotypic resistance patterns.
Genomic analysis and antimicrobial resistance in human- and poultry-derived Campylobacter jejuni isolates from Hangzhou, China.
The study identified several AMR genes and mutations in Campylobacter jejuni isolates, including gyrA mutations (T86I and T86V) associated with quinolone resistance, tet(O) for tetracycline resistance, and various beta-lactamase genes (blaOXA-61, blaOXA-193, blaOXA-450, blaOXA-451, blaOXA-452, blaOXA-453, blaOXA-489) linked to beta-lactam resistance. Additionally, aminoglycoside resistance genes APH(3')-IIIa and ant(6)-Ia were found in some isolates.
Global analysis of the genomic diversity, antimicrobial resistance and potential vaccine candidates carried by the major global bovine pathogen Streptococcus uberis.
The study identified 35% of S. uberis isolates carrying acquired antimicrobial resistance genes, including ant(6)-la, aph(3')-lla, tetL, tetM, tetS, lnuC, and lnuD. Additionally, mutations in penicillin-binding proteins pbp2b (N366I, T402I) and pbp2x (E381K, Q554E, V590A, G600E) were associated with reduced penicillin susceptibility.
Genomic and clinical characterization of linezolid resistance in Enterococcus species from cancer patients in China.
The study identified the optrA gene as the primary mechanism of linezolid resistance in Enterococcus species from cancer patients in China, along with other resistance genes such as tet(M), erm(A), and erm(B).
Isolation and Molecular Characterization of Three Staphylococcus pseudintermedius Strains from Dogs and Humans in Egypt.
Three Staphylococcus pseudintermedius isolates from dogs and humans in Egypt were characterized. The isolates showed resistance to various antibiotics, including penicillin, tetracycline, aminoglycosides, chloramphenicol, fusidic acid, macrolides, streptothricin, and trimethoprim. None of the isolates carried the mecA gene, which is associated with methicillin resistance.
Molecular epidemiology and antibiotic resistance of group B Streptococcus in pregnant women and neonates from Haikou, China: implications for vaccine development and antimicrobial stewardship.
The study identified high rates of tetracycline (89.1%) and clindamycin (55.1%) resistance in GBS strains from Haikou, China. Key resistance genes included mreA, ermB, tetM, catQ, cat(pC194), ant(6)-Ia, aph(3')-III, and aac(6')-aph(2'').
Phenotypic and genomic analysis of the emerging poultry pathogen Enterococcus cecorum in UK isolates.
The study identifies multiple AMR genes and mutations in UK E. cecorum isolates, including tet(L), tet(M), ant(6)-la, ermB, NarA/NarB, and lnuC, as well as mutations in pbp2x and gyrA that confer resistance to various antibiotics.
Antibiotic resistance in mastitis-causing bacteria: Exploring antibiotic-resistance genes, underlying mechanisms, and their implications for dairy animal and public health.
The study identifies several AMR genes and mutations in Staphylococcus aureus and coagulase-negative staphylococci associated with mastitis, including blaZ, mecA, tetK, tetM, aphA3, aacA-aphD, aadD, ermA, msrA, mphC, lnuB, and vanA, which confer resistance to various antibiotics such as β-lactams, tetracyclines, aminoglycosides, macrolides, and glycopeptides.
Emergence of Livestock-Associated Methicillin-Resistant Staphylococcus aureus ST398 in Wild Birds, Brazil.
The study reports the first detection of livestock-associated Methicillin-Resistant Staphylococcus aureus ST398 in wild birds in Brazil, highlighting the emergence of antimicrobial-resistant S. aureus in a protected Atlantic Forest fragment. The MRSA isolates exhibited a broad resistome, including genes for resistance to multiple antimicrobial classes.
Geographics and bacterial networks differently shape the acquired and latent global sewage resistomes.
The study identifies several AMR genes, including aph(6)-id_2, mef(c), mef(b), mph(e), mph(g), msr(d), lnu(b), lnu(d), aadA, ant(6)-Ia, blaCTX-M, blaTEM, blaSHV, blaOXA, qnrS1, mcr-1, and vanA, which are associated with resistance to various antibiotics such as aminoglycosides, macrolides, lincosamides, beta-lactams, fluoroquinolones, polymyxins, and glycopeptides.
Temporal dynamics of the resistome in gilts raised in an organic operation in which semen used for artificial insemination is the primary source of antimicrobial exposure.
The study identified several tetracycline, aminoglycoside, and MLS resistance genes in the fecal microbiome of gilts, with no significant increases in ARG abundance following exposure to semen extenders containing antibiotics.
Genomic Insights into Multidrug-resistant Mammaliicoccus sciuri Carrying Novel Staphylococcal Cassette Chromosome mec (SCCmec) Elements and Plasmids from Farm Ruminants on the East Coast of Peninsular Malaysia.
The study identified multiple antimicrobial resistance genes in four multidrug-resistant Mammaliicoccus sciuri isolates from farm ruminants in Peninsular Malaysia, including mecA, ermY, mphC, msrA, tetL, tetS, aadD, ant(6)-Ia, aac(6')-Ie-aph(2")-Ia, fexA, icaA, icaB, icaC, icaD, icaR, sspA, ndk, and lgt. These genes confer resistance to various antibiotics, including β-lactams, macrolides, tetracyclines, aminoglycosides, and chloramphenicol.
Prophage φEr670 and Genomic Island GI_Er147 as Carriers of Resistance Genes in Erysipelothrix rhusiopathiae Strains.
The study identifies the prophage φEr670 carrying lnuB and lsaE genes, and the genomic island GI_Er147 carrying ant(6)-Ia, spw, lnu(J), and vat family genes in E. rhusiopathiae strains. These genes confer resistance to lincomycin, tetracycline, streptomycin, and spectinomycin.
Use of molecular and reference susceptibility testing methods in a multicenter evaluation of MicroScan dried overnight gram-positive MIC panels for detection of vancomycin and high-level aminoglycoside resistances in enterococci.
The study evaluated the ability of MicroScan PM-8 panels to detect vancomycin resistance (VR) and high-level aminoglycoside resistance (HLAR) in enterococci, comparing them to reference methods. It identified and validated several AMR genes including vanA, vanB, vanC1, vanC2-3, ANT(6)-I, AAC(6')-Ib, and APH(2")-I.
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