Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
APH(3')
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| APH(3')-IXa | Card Database | 1 | - | Acinetobacter gerneri DSM 14967 = CIP 107464 = MTCC 9824 | - | - | APPN01000061.1 | ENV34035.1 |
| aph-3-1 | Reslit | 3 | gentamicin | Campylobacter coli +2 | Tanzania, Northeastern Ohio, the United States|Northeastern Ohio, Kenya | 2016, 2021, 2023 | OQ389471|OQ389472|OQ389473|OQ390085|OQ390086|OQ421183|OQ421184 | - |
| aph(3')-la | Reslit | 3 | aminoglycosides | Klebsiella pneumoniae ST437 +3 | UK, India | 2016, 2020, 2024 | LART00000000|LAXC00000000|LART01000000|LAXC01000000 | - |
| aph(3'')-Ib_5 | Reslit | 1 | gentamicin, tobramycin | Salmonella enterica subsp. enterica serovar Enteritidis +1 | Kuwait | 2019 | PRJNA363099 | - |
| aph(3')-Ia_1 | Reslit | 2 | gentamicin, tobramycin +1 | Salmonella enterica subsp. enterica serovar Enteritidis +2 | Kuwait, Brazil | 2019, 2020 | PRJNA363099 | - |
| aph(3")-Ib_5 | Reslit | 1 | streptomycin | Salmonella enterica subsp. enterica serovar 1,4,[5],12:i:- | Italy | 2019 | - | - |
| aph3'-1 | Reslit | 1 | tobramycin | Escherichia coli | - | 2019 | PRJNA521456 | - |
| aph(3')-lb | Reslit | 3 | aminoglycosides, kanamycin +1 | Pseudomonas aeruginosa +2 | Pakistan|United States|USA, South Korea, Tanzania | 2019, 2021, 2022 | GCF_000746645.1|GCF_000174395.2 | - |
| aph(3")-lld | Reslit | 1 | streptomycin | Salmonella enterica serovar Rissen | China | 2020 | - | - |
| aph(3′')-Ib [strA] | Reslit | 1 | streptomycin | Enterobacter cloacae complex | Guadeloupe|French West Indies | 2021 | PRJNA649757|PRJNA659514 | - |
| aph(3″)-lb | Reslit | 2 | gentamicin, aminoglycosides | Escherichia coli +1 | Singapore | 2021, 2025 | PRJNA398288 | - |
| aph(3'' )-Ib_5 | Reslit | 1 | aminoglycosides | Salmonella enterica | Europe|Denmark|France|Germany|United Kingdom | 2021 | MF684783.1|CP055956.1|CP057682.1|CP055697.1|KF152885|HQ023861|KC853435.1|CP039562.1|MF543359.1 | - |
| aph(3')-VIe | Reslit | 1 | gentamicin, tobramycin +1 | Acinetobacter spp. +4 | Iran | 2022 | - | - |
| aph(3")-lb | Reslit | 4 | gentamicin, streptomycin +1 | Salmonella enterica subsp. enterica +1 | Vietnam, India, Europe, West Texas, USA | 2022, 2023 | CP002895|NG_050417.1|NG_055505.1|MF449287|PRJEB44046 | - |
| aph3-dprime | Reslit | 1 | aminoglycosides | human | United States | 2022 | - | - |
| aph (3)-IIa (aphA2) | Reslit | 1 | gentamicin, amikacin | Listeria monocytogenes | Eastern Cape province, South Africa|South Africa | 2022 | - | - |
| aph(3)-Ia.v1 | Reslit | 1 | aminoglycosides | Klebsiella pneumoniae | United States | 2022 | NC_006625.1|NCBI123456|NCBI789012 | - |
| aph(3")-lll | Reslit | 1 | gentamicin | Campylobacter coli | China | 2022 | PRJNA817390 | - |
| Aph(3')-la | Reslit | 1 | neomycin, kanamycin | Escherichia coli | India | 2022 | NZ_CP098739.1 | - |
| aph(3″)-Ib (strA) | Reslit | 1 | aminoglycosides | Klebsiella pneumoniae | China | 2022 | CP093151|CP093152|CP093153 | - |
| aph(3')-llc | Reslit | 1 | aminoglycosides | Stenotrophomonas maltophilia +1 | North America | 2023 | ON624157|ON624158|JAMOKY000000000|JAMOKZ000000000 | - |
| aph(3)-Ia_3 | Reslit | 1 | aminoglycosides | Salmonella enterica | Hanoi, Vietnam | 2023 | SRR16611133|SRR16611134|SRR16611135|SRR16611136|SRR16611137|SRR16611138|SRR16611139|SRR16611140 | - |
| APH(3')-H48 | Reference Gene Catalog | 1 | KANAMYCIN | Pseudomonas aeruginosa | - | 2023 | LLMY01000085.1 | KSF25789.1 |
| aph(3)-la | Reslit | 1 | streptomycin, kanamycin | Gallibacterium anatis biovar haemolytica | Poland | 2023 | SRX19225671|SRX19225672|SRX19225673|SRX19225674|SRX19225675|SRX19225676|SRX19225677|SRX19225678|SRX19225679|SRX19225680|SRX19225681|SRX19225682|SRX19225683|SRX19225684|SRX19225685|SRX19225686|SRX19225687|SRX19225688|SRX19225689|SRX19225690|SRX19225691|SRX19225692|SRX19225693|SRX19225694|SRX19225695|SRX19225696|SRX19225697|SRX19225698|SRX19225699|SRX19225700|SRX19225701|SRX19225702|SRX19225703|SRX19225704|SRX19225705|SRX19225706|SRX19225707|SRX19225708|SRX19225709|SRX19225710 | - |
| aph(3)-lb | Reslit | 1 | streptomycin, kanamycin | Gallibacterium anatis biovar haemolytica | Poland | 2023 | SRX19225671|SRX19225672|SRX19225673|SRX19225674|SRX19225675|SRX19225676|SRX19225677|SRX19225678|SRX19225679|SRX19225680|SRX19225681|SRX19225682|SRX19225683|SRX19225684|SRX19225685|SRX19225686|SRX19225687|SRX19225688|SRX19225689|SRX19225690|SRX19225691|SRX19225692|SRX19225693|SRX19225694|SRX19225695|SRX19225696|SRX19225697|SRX19225698|SRX19225699|SRX19225700|SRX19225701|SRX19225702|SRX19225703|SRX19225704|SRX19225705|SRX19225706|SRX19225707|SRX19225708|SRX19225709|SRX19225710 | - |
| aph(3")-Ib (str A) | Reslit | 1 | gentamicin | Salmonella enterica | Italy | 2023 | PRJNA817603 | - |
| aph(3'')-lb | Reslit | 2 | aminoglycosides | Proteus mirabilis MCS +4 | Brazil|Belgium, China | 2023, 2024 | NC_047858|NC_027390|NC_027379|NC_28916|NC_047920 | - |
| aph(3)-ld | Reslit | 1 | aminoglycosides | Salmonella enterica | - | 2023 | - | - |
| aph(3''-lb | Reslit | 1 | aminoglycosides | Escherichia coli | North Carolina | 2024 | SRR19429162|SRR19429165|SRR19688157|SRR19688156|SRR21049981|SRR21049979|SRR21753579|SRR21753568|SRR21753577|SRR23322072|SRR22430168|SRR22430167|SRR22430167|SRR22430166|SRR22430173|SRR22430176|SRR23601518|SRR23601518|SRR23322077 | - |
| aph(3')-llb | Reslit | 2 | aminoglycosides | Pseudomonas aeruginosa +1 | India, Bangladesh | 2024, 2025 | CP098765|CP098766 | - |
| aph(3")-Ib_3 | Reslit | 1 | aminoglycosides | Acinetobacter sp. +4 | - | 2024 | - | - |
| APH(3")-lb | Reslit | 1 | streptomycin | Salmonella enterica | Israel | 2025 | PRJNA997248 | - |
| aph(3')-Illa | Reslit | 1 | gentamicin, streptomycin | B. breve | - | 2025 | - | - |
| aph-3-lb | Reslit | 1 | kanamycin | Escherichia coli | Ibadan, Nigeria | 2025 | PRJEB8667 | - |
| aph(3′)-IIb_2 | Reslit | 1 | aminoglycosides | Pseudomonas aeruginosa P37 +1 | South Africa | 2025 | OR122642|OR122643|OR122644|OR122645|OR122646|JBDJPE000000000|JBDJPD000000000|OR122642–OR122646|MK075818.1h|MK075815.1 | - |
| aph(3')-lla | Reslit | 1 | aminoglycosides | Streptococcus uberis | Australia|Czech Republic|Italy|New Zealand | 2025 | PRJNA1173866 | - |
| aph(3')-III3a | Reslit | 1 | gentamicin | Staphylococcus aureus | Brazil | 2025 | - | - |
Prevalence and Antimicrobial Resistance of Campylobacter Isolated from Dressed Beef Carcasses and Raw Milk in Tanzania.
The study identified blaOXA-61, cmeB, tet(O), and aph-3-1 as the primary antimicrobial resistance genes in Campylobacter isolates from raw milk and beef carcasses in Tanzania.
SSTAR, a Stand-Alone Easy-To-Use Antimicrobial Resistance Gene Predictor.
The study presents SSTAR, a software tool for identifying antimicrobial resistance (AR) genes from whole-genome sequencing data. It detects known AR genes and potential new variants, including truncated forms. The tool was applied to analyze resistance genes in Klebsiella pneumoniae ST437 and Escherichia coli ST44, revealing various beta-lactamases, aminoglycoside resistance genes, and porin mutations contributing to resistance.
Non-typhoidal Salmonella blood stream infection in Kuwait: Clinical and microbiological characteristics.
The study identified several AMR genes and mutations in non-typhoidal Salmonella isolates from Kuwait, including aac(6')-Iaa_1, aph(3'')-Ib_5, aph(3')-Ia_1, aph(6)-Id_1, blaCARB-2_1, blaTEM-1B_1, dfrA5_1, floR_2, sul2_2, tet(A)_6, tet(G)_2, and mutations in the gyrA gene. These genes and mutations were associated with resistance to various antibiotics such as aminoglycosides, beta-lactams, trimethoprim, chloramphenicol, sulfamethoxazole, tetracycline, and fluoroquinolones.
Non-typhoidal Salmonella blood stream infection in Kuwait: Clinical and microbiological characteristics.
The study identified several AMR genes and mutations in non-typhoidal Salmonella isolates from Kuwait, including aac(6')-Iaa_1, aph(3'')-Ib_5, aph(3')-Ia_1, aph(6)-Id_1, blaCARB-2_1, blaTEM-1B_1, dfrA5_1, floR_2, sul2_2, tet(A)_6, tet(G)_2, and mutations in the gyrA gene. These genes and mutations were associated with resistance to various antibiotics such as aminoglycosides, beta-lactams, trimethoprim, chloramphenicol, sulfamethoxazole, tetracycline, and fluoroquinolones.
First report of Salmonella 1,4,[5],12:i:- in free-ranging striped dolphins (Stenella coeruleoalba), Italy.
The study identifies several AMR genes in Salmonella 1,4,[5],12:i:- isolates from striped dolphins, including aph(3")-Ib_5, aph(6)-Id_1, blaTEM-1B_1, sul2_3, and tet(B)_4, which confer resistance to aminoglycosides, beta-lactams, sulfonamides, and tetracyclines.
Clinical Resistome Screening of 1,110 Escherichia coli Isolates Efficiently Recovers Diagnostically Relevant Antibiotic Resistance Biomarkers and Potential Novel Resistance Mechanisms.
The study identifies several AMR genes including aac(3)-IIa, aac(6')-lb-cr, ant (2")-Ia, aph3'-1, dfrA14, dfrA17, sul1, and qnrB19, which confer resistance to Tobramycin, Ciprofloxacin, and Trimethoprim-Sulfamethoxazole. These genes were validated through cloning and MIC testing.
Spatiotemporal dynamics of multidrug resistant bacteria on intensive care unit surfaces.
The study identified various AMR genes, including bla OXA-23, bla OXA-66, bla NDM-1, bla NDM-5, bla NDM-7, bla OXA-181, bla OXA-232, erm(B), vanA, msr(C), fosA, oqxA, aph(3')-lb, bla PAO, bla OXA-50, catB7, and bla GES-5, in multidrug-resistant bacteria isolated from ICU surfaces in Pakistan and the USA.
Preterm infants harbour diverse Klebsiella populations, including atypical species that encode and produce an array of antimicrobial resistance- and virulence-associated factors.
The study identified various antimicrobial resistance genes in Klebsiella isolates from preterm infants, highlighting the presence of multidrug resistance mechanisms.
Characterization of Multidrug Resistance Patterns of Emerging Salmonella enterica Serovar Rissen along the Food Chain in China.
The study identified multiple AMR genes in Salmonella enterica serovar Rissen isolates, including tet(A), blaTEM-1B, aadA2, aadA1, aac(6')-Iaa, aph(3")-lld, sul3, and dfrA12, which confer resistance to various antibiotics such as tetracycline, ampicillin, streptomycin, sulfisoxazole, and trimethoprim-sulfamethoxazole.
Genomic Characterization of Salmonella Minnesota Clonal Lineages Associated with Poultry Production in Brazil.
The study identified multiple antimicrobial resistance genes, including aac(6')-Iaa, mdf(A), sul2, tet(A), blaCMY-2, aph(3')-Ia_1, qnrB19, and ant(3'')-Ia, in Salmonella Minnesota isolates from Brazilian poultry farms, indicating widespread resistance to various antibiotics.
Dissemination of Extended-Spectrum-β-Lactamase-Producing Enterobacter cloacae Complex from a Hospital to the Nearby Environment in Guadeloupe (French West Indies): ST114 Lineage Coding for a Successful IncHI2/ST1 Plasmid.
The study identifies the blaCTX-M-1 gene carried on an IncI1/ST3 plasmid in Enterobacter cloacae and Escherichia coli isolates from humans and wild animals in Guadeloupe, highlighting the dissemination of this resistance determinant in the environment.
Genomic and phenotypic analyses of multidrug-resistant Acinetobacter baumannii NCCP 16007 isolated from a patient with a urinary tract infection.
The study identifies multiple AMR genes and mutations in the multidrug-resistant A. baumannii NCCP 16007 strain, including pmrC, pmrB, blaOXA-23, and various aminoglycoside, tetracycline, and beta-lactam resistance genes, contributing to its high resistance to polymyxin B and other antibiotics.
Characterization of Extended-Spectrum Beta-Lactamase-Producing Escherichia coli Isolates from Jurong Lake, Singapore with Whole-Genome-Sequencing.
The study identified several extended-spectrum beta-lactamase (ESBL) genes, including bla CTX-M-15, bla CTX-M-8, bla CTX-M-27, bla CTX-M-14, and bla CTX-M-55, along with mcr-1.1 and mcr-3.1 for colistin resistance. Additionally, various other resistance genes such as qnrS1, mdf(A), mph(A), and others were found in the isolates, indicating multidrug resistance.
The Spatiotemporal Dynamics and Microevolution Events That Favored the Success of the Highly Clonal Multidrug-Resistant Monophasic Salmonella Typhimurium Circulating in Europe.
The study identifies various AMR genes in the highly clonal multidrug-resistant monophasic Salmonella Typhimurium ST34, including beta-lactamases, sulfonamide resistance genes, tetracycline resistance genes, phenicol resistance genes, and polymyxin resistance genes.
Prevalence and Antimicrobial Resistance Profiles of Foodborne Pathogens Isolated from Dairy Cattle and Poultry Manure Amended Farms in Northeastern Ohio, the United States.
The study identified several antimicrobial resistance genes in foodborne pathogens isolated from dairy cattle and poultry manure amended farms in Northeastern Ohio, including mphA, aadA, aphA1, tetA, aac(3)-IV, sulII, blaTEM, tetB, strA, aac(3)-Iva, ampC, lde, ermB, tet(O), aadB, penA, blaOXA-61, aadE, and aph-3-1.
Evaluation of phenotypic and genotypic patterns of aminoglycoside resistance in the Gram-negative bacteria isolates collected from pediatric and general hospitals.
The study identified several aminoglycoside resistance genes, including aac(6')-Ib, aph(3')-VIe, aadA15, aph(3')-Ia, aph(3')-II, and aph(6), which were prevalent among Gram-negative bacteria isolates in Iran.
First identification of bla (NDM-5) producing Escherichia coli from neonates and a HIV infected adult in Tanzania.
The study identifies bla NDM-5 producing Escherichia coli in Tanzania, highlighting the presence of carbapenem resistance and other resistance genes on various plasmids.
Analysis of Antimicrobial Resistance in Non-typhoidal Salmonella Collected From Pork Retail Outlets and Slaughterhouses in Vietnam Using Whole Genome Sequencing.
The study identified several AMR genes in non-typhoidal Salmonella isolates from pork retail outlets and slaughterhouses in Vietnam, including blaTEM-1, blaTEM-150, blaLAP-2, blaCTX-M-55, dfrA12, dfrA14, floR, cmlA1, tetA, tetB, tetM, mcr-1, mcr-3, qnrS1, mphA, aadA1, aadA2, aac(6')-laa, aac(6')-ly, sul1, sul2, sul3, aph(3")-lb, and aph6-ld. These genes conferred resistance to various antibiotics such as ampicillin, penicillins, first-generation cephalosporins, quinolones, trimethoprim, chloramphenicol, tetracycline, colistin, macrolides, gentamicin, sulfonamides, and others.
Association of Diet and Antimicrobial Resistance in Healthy U.S. Adults.
The study found that aminoglycoside resistance was the most common mechanism of antimicrobial resistance in healthy U.S. adults, and that aminoglycoside-O-phosphotransferase (aph3-dprime) correlated negatively with fiber intake.
Assessment of multidrug-resistant Listeria monocytogenes in milk and milk product and One Health perspective.
The study identified multiple antimicrobial resistance genes in Listeria monocytogenes isolates from milk and milk products, including beta-lactamase genes (bla TEM, bla SHV, bla Z), tetracycline resistance genes (tet A, tet D, tet G, tet K, tet M), sulfonamide resistance genes (sul 1, sul 2), and an aminoglycoside resistance gene (aph (3)-IIa (aphA2)).
Genomic surveillance for multidrug-resistant or hypervirulent Klebsiella pneumoniae among United States bloodstream isolates.
The study identified various antimicrobial resistance genes and mutations in Klebsiella pneumoniae bloodstream isolates, highlighting the presence of multidrug-resistant and hypervirulent strains in the United States.
Withdrawal of antibiotic growth promoters in China and its impact on the foodborne pathogen Campylobacter coli of swine origin.
The study found that the withdrawal of antibiotic growth promoters in China led to an increase in antibiotic resistance in Campylobacter coli, particularly for gentamicin and florfenicol. Several resistance genes, including aadE-Cc, aac(6')-aph(2"), ant(6)-la, aph(3")-lll, aph(2")-lf, tet(O), tet(M), tet(O/32/O), cat, fexA, cfr(C), optrA, blaOXA-193, blaOXA-489, and blaOXA-61, were identified. Mutations in 23S rRNA and gyrA were also associated with resistance to erythromycin and ciprofloxacin, respectively.
Whole genome sequencing and characteristics of extended-spectrum beta-lactamase producing Escherichia coli isolated from poultry farms in Banaskantha, India.
The study identified multiple extended-spectrum beta-lactamase (ESBL) genes, including bla TEM, bla SHV, bla OXA, and bla CTX-M subtypes, along with plasmid-mediated AMR genes such as qnrS1, tetA, dfrA14, sul2, aph(3")-lb, aph(6)-ld, and Aph(3')-la in ESBL-producing E. coli isolates from poultry farms in India.
Whole genome sequencing and characteristics of extended-spectrum beta-lactamase producing Escherichia coli isolated from poultry farms in Banaskantha, India.
The study identified multiple extended-spectrum beta-lactamase (ESBL) genes, including bla TEM, bla SHV, bla OXA, and bla CTX-M subtypes, along with plasmid-mediated AMR genes such as qnrS1, tetA, dfrA14, sul2, aph(3")-lb, aph(6)-ld, and Aph(3')-la in ESBL-producing E. coli isolates from poultry farms in India.
Coexistence of Multidrug Resistance and Virulence in a Single Conjugative Plasmid from a Hypervirulent Klebsiella pneumoniae Isolate of Sequence Type 25.
The study identifies a conjugative plasmid pCY814036-iucA carrying multidrug resistance genes and virulence factors, and another plasmid pCY814036-KPC2 harboring bla KPC-2 and rmtB, contributing to carbapenem resistance and hypervirulence in a Klebsiella pneumoniae isolate.
Characterization of Antibiotic-Resistant Stenotrophomonas Isolates from Painted Turtles Living in the Wild.
Two Stenotrophomonas isolates, Stenotrophomonas sp. 9A and S. maltophilia 15A, were found to exhibit multidrug resistance. Key resistance mechanisms included chromosomal beta-lactamases (blaL1 and blaL2), aminoglycoside resistance genes (aac(6')-lz and aph(3')-llc), and efflux pumps (smeABC and smeDEF).
Longitudinal study of the short- and long-term effects of hospitalisation and oral trimethoprim-sulfadiazine administration on the equine faecal microbiome and resistome.
Oral trimethoprim-sulfadiazine (TMS) administration leads to a significant and long-lasting increase in the relative abundance of resistance genes sul2, tetQ, ant6-1a, aph(3"-lb, and lnuC in the equine faecal microbiome.
Whole-Genome Analysis of Antimicrobial-Resistant Salmonella enterica Isolated from Duck Carcasses in Hanoi, Vietnam.
The study identified 43 antibiotic resistance genes in Salmonella enterica isolates from duck carcasses in Hanoi, Vietnam, including genes conferring resistance to multiple antibiotic classes such as aminoglycosides, beta-lactams, quinolones, and tetracyclines.
Antimicrobial Usage, Susceptibility Profiles, and Resistance Genes in Campylobacter Isolated from Cattle, Chicken, and Water Samples in Kajiado County, Kenya.
The study identified several AMR genes in Campylobacter isolates, including tet(O), blaOXA-61, aph-3-1, gyrA, and cmeB, which confer resistance to tetracycline, ampicillin, gentamicin, ciprofloxacin, and multiple antibiotics. High levels of multidrug resistance were observed, highlighting the urgent need for improved antimicrobial stewardship.
Genomic Characterization of Fecal Escherichia coli Isolates with Reduced Susceptibility to Beta-Lactam Antimicrobials from Wild Hogs and Coyotes.
The study identified beta-lactamase genes (blaCMY-2, blaCTX-M-55, blaCTX-M-27), tetracycline resistance genes (tetA, tetB, tetC), aminoglycoside resistance genes (aac(3)-IId, aadA5, ant(3")-Ia, aph(3')-Ia, aph(3")-lb, aph(6)-ld), sulfonamide resistance genes (sul1, sul2, sul3), amphenicol resistance gene (floR), trimethoprim resistance genes (dfrA1, dfrA17), and MLS resistance genes (Inu(F), erm(B), mph(A)) in E. coli isolates from coyotes and wild hogs. Additionally, chromosomal mutations in ampC, gyrA, parC, and parE were found to confer resistance to beta-lactam and quinolone antibiotics.
Extensive screening reveals previously undiscovered aminoglycoside resistance genes in human pathogens.
Isolation and characterization of multidrug resistant Gallibacterium anatis biovar haemolytica strains from Polish geese and hens.
The study identified 25 different antimicrobial resistance genes in multidrug-resistant Gallibacterium anatis biovar haemolytica strains from Polish geese and hens, including tetB, blaTEM-1, blaROB-1, floR, sul2, sul3, dfrK, aadA1, aadA2, aph(3)-la, aph(3)-lb, aph(6)-ld, sat2, dfrA14, dfrA32, merC, merP, merR, merT, qacL, and cmlA1.
Isolation and characterization of multidrug resistant Gallibacterium anatis biovar haemolytica strains from Polish geese and hens.
The study identified 25 different antimicrobial resistance genes in multidrug-resistant Gallibacterium anatis biovar haemolytica strains from Polish geese and hens, including tetB, blaTEM-1, blaROB-1, floR, sul2, sul3, dfrK, aadA1, aadA2, aph(3)-la, aph(3)-lb, aph(6)-ld, sat2, dfrA14, dfrA32, merC, merP, merR, merT, qacL, and cmlA1.
Phenotypic and genotypic antimicrobial resistance correlation and plasmid characterization in Salmonella spp. isolates from Italy reveal high heterogeneity among serovars.
The study identified several antimicrobial resistance genes including blaTEM-1B, sul1, sul2, tetA, tetB, and others in Salmonella isolates from Italy, highlighting the diversity of resistance mechanisms among different serovars.
Isolation and Characterization of the Acadevirus Members BigMira and MidiMira Infecting a Highly Pathogenic Proteus mirabilis Strain.
The study identifies multiple antibiotic resistance genes in the highly pathogenic Proteus mirabilis strain MCS, highlighting its multidrug-resistant profile. Key genes include tetA, aac(6')-Iq, aac(6')-Ib', aadA, dfrA1, blaOXA-9, blaCTX-M-2, vat, catA2, sul1, qacEdeltal, tetQ, blaTEM-135, aadA2, aph(3')-Ia, aph(6)-Id, aph(3'')-lb, and sulI.
Serovars, Virulence and Antimicrobial Resistance Genes of Non-Typhoidal Salmonella Strains from Dairy Systems in Mexico.
Characteristics of antimicrobial resistance in Escherichia coli isolated from retail meat products in North Carolina.
The study identified several AMR genes in E. coli isolates from retail meat products in North Carolina, including aac(3)-IV, aadA1, aph(3'')-lb, blaTEM-1, tetB, and others, highlighting the prevalence of multidrug-resistant E. coli in ground turkey.
Mechanism for transmission and pathogenesis of carbapenem-resistant Enterobacterales harboring the carbapenemase IMP and clinical countermeasures.
The study identifies blaIMP-4 and blaIMP-26 as carbapenemase genes responsible for carbapenem resistance in Enterobacterales. Additionally, various other AMR genes such as aac(6')-lb3, armAC, aph(3'')-lb, aph(6)-ld, aadA5, aac(6')-llc, aac(3)-IId, dfrA19, dfrA1, sul1, tet(D), tet(A), qnrS1, qnrB4, msr(E), mph(E), ere(A), mph(A), mcr-9, and ARR-3 were characterized for their roles in resistance to different antibiotics.
An in-depth study on survival mechanism of bacterial isolates in disinfectants within the hospital environment.
The study identified multiple AMR genes, including blaDIM-1, qacE, and various efflux pump genes, in bacterial isolates from hospital disinfectants, indicating their adaptation to survive in disinfectant environments.
An in-depth study on survival mechanism of bacterial isolates in disinfectants within the hospital environment.
The study identified multiple AMR genes, including blaDIM-1, qacE, and various efflux pump genes, in bacterial isolates from hospital disinfectants, indicating their adaptation to survive in disinfectant environments.
Metagenomic assemblies tend to break around antibiotic resistance genes.
The study evaluates the performance of various metagenomic assemblers in capturing antibiotic resistance genes (ARGs) and their genomic contexts, highlighting challenges in accurately reconstructing ARGs from short-read data.
Genetic diversity of Salmonella enterica during acute human infections.
The study identifies variations in antibiotic resistance gene (ARG) carriage among same-patient Salmonella isolates, particularly highlighting the presence of APH(6)-Id and APH(3")-lb genes associated with streptomycin resistance.
Human milk oligosaccharide metabolism and antibiotic resistance in early gut colonizers: insights from bifidobacteria and lactobacilli in the maternal-infant microbiome.
The study investigated the metabolism of human milk oligosaccharides (HMOs) by bifidobacteria and lactobacilli isolated from human milk and mother-infant fecal samples, along with their antibiotic resistance profiles. Bifidobacterium bifidum showed the highest HMO degradation capability and was the most antibiotic-susceptible species, whereas Bifidobacterium animalis subsp. lactis was resistant to most tested antibiotics.
Transmissible antimicrobial resistance in Escherichia coli isolated from household drinking water in Ibadan, Nigeria.
The study identified several AMR genes in E. coli isolates from household water in Ibadan, Nigeria, including blaTEM-1B, dfrA14, tetA, qnrS1, and mcr-1, highlighting the potential for horizontal gene transfer and the risk of AMR spread in the environment.
Uncovering antibiotic resistance: extended-spectrum beta-lactamase-producing Pseudomonas aeruginosa from dipteran flies in residential dumping and livestock environments.
The study identified multiple antibiotic resistance genes in Pseudomonas aeruginosa isolates from dipteran flies, including genes conferring resistance to aminoglycosides, sulfonamides, beta-lactams, chloramphenicol, fosfomycin, and others.
Molecular and genomic insights into multidrug-resistant (MDR) and extensively drug-resistant (XDR) Pseudomonas aeruginosa causing burn wound infections in Bangladesh.
The study identified multiple beta-lactamase genes, including blaNDM-1, blaVIM-2, blaPER-1, blaCTX-M, blaOXA-1, and blaOXA-48, as well as efflux pump genes like mexA, mexC, and mexE, contributing to multidrug resistance in P. aeruginosa isolates from burn wound infections in Bangladesh.
Global analysis of the genomic diversity, antimicrobial resistance and potential vaccine candidates carried by the major global bovine pathogen Streptococcus uberis.
The study identified 35% of S. uberis isolates carrying acquired antimicrobial resistance genes, including ant(6)-la, aph(3')-lla, tetL, tetM, tetS, lnuC, and lnuD. Additionally, mutations in penicillin-binding proteins pbp2b (N366I, T402I) and pbp2x (E381K, Q554E, V590A, G600E) were associated with reduced penicillin susceptibility.
Genomic insights into bacteriophages: a new frontier in AMR detection and phage therapy.
The paper discusses the identification of various AMR genes in Acinetobacter baumannii and other pathogens, highlighting their role in resistance to multiple antibiotics and the potential of phage therapy as an alternative treatment.
High colonization by multidrug-resistant and virulent Staphylococcus aureus genotypes among critically ill patients in the COVID-19 pandemic in a Brazilian hospital.
The study identified multiple AMR genes in MRSA isolates from critically ill patients during the COVID-19 pandemic, including erm(C), msr(A), mph(C), smr, aph(3')-III3a, and various virulence genes such as sasG, ebpS, scn, egc_cluster, fnbpB, cna, and pvl.
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