Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
aminoglycoside phosphotransferase
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| APH(3')-IIc | Card DatabaseReference Gene CatalogReslit | 10 | kanamycin, neomycin +3 | Escherichia coli +3 | China, Lithuania, United Kingdom | 2007, 2008, 2020, 2023, 2024, 2025 | HQ424460.1 | ADQ43421.1 |
| aph(3')-IIc | ResFinder Database | 1 | NEOMYCIN, PAROMOMYCIN +2 | Stenotrophomonas maltophilia K279a | - | 2008 | AM743169 | - |
Aph(3′)-IIc, an Aminoglycoside Resistance Determinant from Stenotrophomonas maltophilia
The study characterizes the aph(3')-IIc gene from Stenotrophomonas maltophilia, which encodes an aminoglycoside phosphotransferase that confers resistance to kanamycin, neomycin, butirosin, and paromomycin when expressed in E. coli and in S. maltophilia.
Aph(3')-IIc, an aminoglycoside resistance determinant from Stenotrophomonas maltophilia.
Aph(3')-IIc, an aminoglycoside resistance determinant from Stenotrophomonas maltophilia.
The complete genome, comparative and functional analysis of Stenotrophomonas maltophilia reveals an organism heavily shielded by drug resistance determinants.
The complete genome, comparative and functional analysis of Stenotrophomonas maltophilia reveals an organism heavily shielded by drug resistance determinants.
Antibiotic Resistance Patterns of Pseudomonas spp. Isolated From Raw Milk Revealed by Whole Genome Sequencing.
The study identified various AMR genes and mutations in Pseudomonas spp. isolated from raw milk, highlighting the prevalence of multidrug-resistant strains and the presence of resistance determinants such as beta-lactamases, aminoglycoside-modifying enzymes, and efflux pumps.
Novel Antibiotic Resistance Genes Identified by Functional Gene Library Screening in Stenotrophomonas maltophilia and Chryseobacterium spp. Bacteria of Soil Origin.
The study identified novel variants of aminoglycoside and beta-lactam resistance genes, including aph(3')-IIc, aph(6), ant(6), IND-17, and CHM, which confer resistance to kanamycin, streptomycin, and various beta-lactam antibiotics.
Identification of diverse antibiotic resistant bacteria in agricultural soil with H(2)(18)O stable isotope probing combined with high-throughput sequencing.
The study identified several antimicrobial resistance genes (ARGs) in agricultural soil using H2 18O stable isotope probing combined with high-throughput sequencing. These included aph(3')-IIc, oqxB, blaTEM-181, blaL1, and dfrB3, which conferred resistance to various antibiotics such as aminoglycosides, chloramphenicol, quinolones, trimethoprim, and beta-lactams.
Bacterial dynamics of the plastisphere microbiome exposed to sub-lethal antibiotic pollution.
The study identifies the ciprofloxacin resistance gene aac(6')-Ib-cr and the gentamicin resistance gene aac(6')-IIc, along with the plasmid-borne ciprofloxacin resistance gene qnrB, in the plastisphere microbiome under sub-lethal antibiotic exposure.
Acquired resistance of Stenotrophomonas maltophilia to antimicrobials induced by herbicide paraquat dichloride.
Exposure of Stenotrophomonas maltophilia to paraquat induces multidrug resistance through genetic mutations affecting efflux pumps, ribosomal proteins, and metabolic enzymes.
Genomic analysis of contaminant Stenotrophomonas maltophilia, from placental swab culture, carrying antibiotic resistance: a potential hospital laboratory contaminant.
The study identified six antibiotic resistance genes in Stenotrophomonas maltophilia RAOG732, including aac(6')-Iz, aac(6')-Ib7, aph(3')-IIc, oqxB, sul1, and blaL1, which conferred resistance to aminoglycosides, fluoroquinolones, folate synthesis inhibitors, and beta-lactams.
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