The paper describes a DNA microarray for genotyping antibiotic resistance in Pseudomonas aeruginosa, identifying several resistance genes and mutations associated with various antibiotics.

The study identified various AMR genes in commensal E. coli from pigs, including blaTEM, catA1, aph(3')-Ia, aadA, strA/strB, tet(A), tet(B), sul1, sul2, and sul3. These genes conferred resistance to antibiotics such as ampicillin, chloramphenicol, kanamycin, neomycin, streptomycin, spectinomycin, tetracycline, and sulfamethoxazole. However, the presence of these resistance genes did not provide a significant colonization advantage or disadvantage in the pig intestine.

The paper discusses various aminoglycoside modifying enzymes, particularly focusing on AAC(6')-Ib, AAC(6')-Ib-cr, and AAC(6')-Ib 11, which confer resistance to aminoglycosides like amikacin and gentamicin, and in some cases, quinolones.

The study identified aminoglycoside resistance mechanisms in Gram-negative bacteria, including aac(3)-I, aac(6')-I, ant(2")-I, and aph(3')-I genes, which confer resistance to various aminoglycosides.

The study identified various antimicrobial resistance genes including blaOXA-51-like, blaOXA-23, blaIMP-1, blaVIM-2, aac(6')-Ib, aph(3')-Ia, aph(3')-VI, and armA in imipenem-nonsusceptible Acinetobacter calcoaceticus-baumannii complex isolates. Additionally, mutations in gyrA and parC were found to confer fluoroquinolone resistance.

The study identifies multiple AMR genes and mutations in the EDR A. baumannii 53264 strain, including aac(6')-Iaf, aac(3)-Ia, aph(3')-Ia, aph(3')-Ic, strA/aph(3'')-Ib, blaOXA-23, blaTEM-1, sul1, sul3, and tet(B). Additionally, mutations in ampC, gyrB, parC, and qseC contribute to resistance against various antibiotics.

The study identifies the blaNDM-1 gene on plasmid pKPX-1 as a key factor in carbapenem resistance in a multidrug-resistant Klebsiella pneumoniae isolate. It also characterizes additional resistance genes such as aac(6')-Ib, aac(6')-Ib-cr, aph(3')-I, strB, qnrB, tetA, catA1, and catB4, which contribute to resistance against aminoglycosides, fluoroquinolones, tetracycline, and chloramphenicol.

The study identified various AMR genes and mutations in E. coli and K. pneumoniae isolates, including beta-lactamases (bla TEM-1, bla OXA-1, bla CTX-M-15), aminoglycoside-modifying enzymes (aac(6')-Ib-cr, aadA1a, aadA4, aadA5, aph(6')-Id, aph(3')-Ia), and quinolone resistance mutations (gyrA S83L/D87N, parC S80I/E84V). These genes and mutations were validated through whole-genome sequencing and phenotypic testing.

The study reports the first case of a nosocomial infection in a neonatal ICU in Korea caused by ST357 multidrug-resistant Acinetobacter baumannii strains. The isolates exhibited resistance to several antibiotics, including amikacin, gentamicin, ceftazidime, cefepime, and ciprofloxacin, due to the presence of aac(6')-Ib, aph(3')-Ia, armA, and mutations in gyrA and parC.

The study developed a DNA microarray for genotyping antibiotic resistance determinants in Acinetobacter baumannii clinical isolates, identifying numerous resistance genes and mutations associated with carbapenem, aminoglycoside, fluoroquinolone, and other antibiotic resistances.

The study identified multiple antimicrobial resistance genes in Acinetobacter baumannii isolates from military treatment facilities, including bla OXA-51-like, bla OXA-23, bla GES-11, aac(6')-Ib, aacC1, aadB, aphA6, and others, highlighting the complex resistome of these isolates.

The study identified a diversity of aminoglycoside-modifying enzymes (AMEs) in carbapenem-resistant Klebsiella pneumoniae strains, including aac(6')-Ib, aph(3')-Ia, and aac(3)-IV, which contributed to varying levels of resistance to aminoglycosides such as gentamicin, tobramycin, and plazomicin.

The study describes an outbreak of colistin-resistant KPC-producing K. pneumoniae ST258 in the Netherlands, highlighting the presence of multiple resistance genes including blaKPC-2, blaSHV-12, and various other AMR genes.

The study found that ESBL-plasmid carriage does not reduce fitness but enhances virulence in some strains of pandemic E. coli lineages. It identified several AMR genes on the ESBL-plasmids, including beta-lactamases (blaCTX-M-15, blaCTX-M-27, blaCTX-M-14), tetracycline resistance genes (tetA, tetR), aminoglycoside resistance genes (aadA, aac(6')-Ib-cr), chloramphenicol resistance gene (catB4), sulfonamide resistance gene (sul2), streptomycin resistance genes (strA, strB), dihydrofolate reductase genes (dhfrVII, dfrA17), and aminoglycoside phosphotransferase gene (aph(3')-Ia). Non-antibiotic resistance genes such as finO, traT, icc, yfaX, yihA, and hha were also identified.

The paper discusses various mechanisms of antibiotic resistance, including beta-lactamases like blaKPC, blaNDM, blaIMP, and blaVIM, which confer resistance to carbapenems. It also covers aminoglycoside modifying enzymes such as aac(6')-Ib and aac(6')-I, quinolone resistance proteins like qnr, tetracycline resistance genes such as tet(M) and tet(O), macrolide resistance genes like erm, mefA, and mefE, and efflux pump systems like mexAB-oprM and acrAB-tolC.

The study identified 65 unique resistance genes in nontyphoidal Salmonella, including bla CTX-M1 and bla SHV2a, which were first reported in retail meat isolates in the United States. The research highlights the effectiveness of whole-genome sequencing in detecting antimicrobial resistance genes and correlating them with phenotypic resistance.

The study identifies multiple carbapenemase genes (bla KPC-2, bla KPC-3, bla KPC-4, and bla NDM-1) and other resistance genes (such as qnrB19, qnrB2, qnrS1, bla TEM-1A, bla TEM-1B, bla OXA-9, bla SHV-12, aadA2, aac(6')-Ib, aac(6')-Ib-cr, aph(3')-Ia, aph(3')-Ic, strA, strB, sul1, sul2, dfrA14, dfrA18, mph(A), catB3, arr-3, and tet(D)) in carbapenem-resistant Enterobacter spp. These genes are primarily located on plasmids and contribute to multidrug resistance.

Two novel antibiotic resistance enzymes were identified from the Atlantis II Deep Red Sea brine pool: ATII-APH(3') and ATII-ABL. ATII-APH(3') provides resistance to kanamycin and neomycin, while ATII-ABL does not confer resistance to beta-lactam antibiotics.

The study presents a rapid colorimetric test for detecting multiple aminoglycoside resistance in Enterobacteriaceae, focusing on the identification of 16S rRNA methylases (armA, rmtB, rmtC, rmtF, rmtG, npmA) and aminoglycoside-modifying enzymes (aac(3)-IV, aac(3)-Ia, aac(3)-V, aph(3')-I, aph(3')-Ib, ant(2'')).

The study identified multiple AMR genes in E. coli isolates from marine bivalves, including bla TEM-1, bla CTX-M-14, bla CTX-M-15, and various aminoglycoside, trimethoprim, sulfonamide, tetracycline, chloramphenicol, quinolone, and macrolide resistance genes. These findings highlight the potential risk of MDR Enterobacteriaceae in marine environments.

The study identifies several AMR genes and mutations associated with multidrug-resistant Klebsiella pneumoniae in the UK and Ireland, including beta-lactamases, aminoglycoside-modifying enzymes, tetracycline efflux pumps, and mutations in gyrB contributing to fluoroquinolone resistance.

The study identified several AMR genes and mutations in Salmonella enterica isolates from dairy cattle and humans in New York and Washington States, highlighting the role of geographic and source-specific factors in AMR dissemination.

The study identified multiple AMR genes and mutations in XDR K. pneumoniae isolates, including bla KPC−2, rmtB, aac(6′)-Ib, APH(3′)-Ia, AAC(3)-IV, qnrS, qnrB, aac(6′)-Ib-cr, bla CTX−M−14, bla CTX−M−65, bla SHV−11, bla TEM, bla CMY, bla DHA−1, gyrA, and parC, which contribute to resistance against various antibiotics.

The study identifies several tetracycline resistance genes (tetM, tetW, tetO, tetS), sulfonamide resistance genes (sulI, sulII), and others, showing their expression dynamics during composting and their association with microbial community shifts.

The study identified multiple antimicrobial resistance genes on IncA/C plasmids from various Salmonella serovars, including bla_cmy-2, bla_tem-1, strA, strB, aadB, aph(3')-Ia, tetA, floR, cmlA, sul1, sul2, dfra12, quacE, sugE, merA, merB, merC, merD, and merE, which contribute to multidrug resistance.

The study reveals high prevalence of clinically relevant antibiotic resistance genes in wastewater, particularly in hospital discharge samples, including bla KPC-2, bla OXA, bla NDM, qnrS1, qnrS2, and aph(3"). These genes are associated with resistance to carbapenems, beta-lactams, quinolones, and aminoglycosides.

The study identified aac(6')-Ib, aac(3)-IV, ant(2" )-Ia, and aph(3')-Ia as the most common aminoglycoside-modifying enzymes in multidrug-resistant Pseudomonas aeruginosa clinical isolates, which conferred resistance to various aminoglycosides.

The study identifies two novel groups of kanamycin-resistance ColE1-like plasmids (X and Y/Y2/Y3) in Salmonella enterica serotypes from food animals, with the aph(3')-I gene being responsible for kanamycin resistance.

The study identified several aminoglycoside-modifying enzyme genes (aac(6')-Ib, aac(3)-I, ant(3'')-I, aph(3')-I, aac(6')-Id) and 16S rRNA methylase genes (armA, rmtA) in multidrug-resistant Acinetobacter baumannii isolates in Iran, highlighting their prevalence and contribution to aminoglycoside resistance.

The study identified various AMR genes in Salmonella enterica isolates from equine patients, including beta-lactamases, aminoglycoside modifying enzymes, and genes conferring resistance to tetracyclines, macrolides, and other antibiotics.

The study identified aac(6')-Ib, aac(3)-IIa, and aph(3')-Ia as the most prevalent aminoglycoside-modifying enzymes in Escherichia coli and Klebsiella pneumoniae producing extended spectrum β-lactamases in Spain. These genes were associated with resistance to various aminoglycosides.

The study identified aminoglycoside resistance genes aph(3')I, aph(3')VIa, and armA in multidrug-resistant Acinetobacter baumannii isolates from ICU patients in Northeastern India, contributing to high-level resistance to gentamicin and amikacin.

The study identifies several AMR genes in multidrug-resistant Streptococcus suis isolates, including tetM, lnuB, erm(B), tetO, tetL, and aph3′, which confer resistance to tetracycline, clindamycin, erythromycin, and aminoglycosides.

The study reports the draft genome of a multidrug-resistant Corynebacterium striatum isolate, identifying several resistance genes including tetA, tetB, vanW, ermX, aph(3')-Ia, strA-strB, bla, and cmx, along with a mutation in the gyrA gene contributing to quinolone resistance.

The study identifies multiple antibiotic resistance genes in the newly described species Superficieibacter electus, including beta-lactamases, aminoglycoside modifying enzymes, and others, indicating its ability to resist various antibiotics.

The study identified a novel O89 O-antigen locus in E. coli strain 26561, which is associated with group 1 capsule (G1C) and multidrug resistance. The strain exhibits a mucoid and viscous phenotype, and possesses multiple AMR genes including blaCTX-M-14, blaTEM-1, aph(3")-Ib, strA, aph(6)-Id, strB, aph(3′)-Ia, sul2, tetA(B), and catA1. Mutations in gyrA (S83L, D87N) and parC (S80I) contribute to quinolone resistance.

The study identifies various tetracycline, erythromycin, chloramphenicol, and aminoglycoside resistance genes in Lactobacillus species, highlighting their potential role in antimicrobial resistance and horizontal gene transfer.

The study identifies multidrug-resistant hybrid pathotype Shiga toxin-producing E. coli O80 strains belonging to clonal complex 165, which harbor a mosaic plasmid with genes conferring resistance to multiple antibiotics, including beta-lactams, tetracyclines, sulfonamides, trimethoprim, kanamycin, streptomycin, and colistin.

The study identified six resistance genes (aph3', ant6, bla, sat4, and two ermB) on the plasmid pEC369, along with a vanC-2 gene cluster on the chromosome, contributing to resistance against erythromycin, kanamycin, streptomycin, and vancomycin in Enterococcus casseliflavus EC369.

The study identified the carbapenemase gene blaOXA-237 and intrinsic blaOXA-66 as responsible for carbapenem resistance in Acinetobacter baumannii. Aminoglycoside resistance was mediated by aadA1, aph(3')-Ia, armA, strA, and strB. Quinolone resistance was due to mutations in GyrA (Ser-83-Leu) and ParC (Ser-80-Leu).

The study identified blaTEM as a major contributor to ampicillin resistance and aph(3)-Ia as a determinant of gentamicin resistance in E. coli isolates from pregnant women in Ghana.

The study identifies the expression of AMR genes bla KPC−2, bla TEM−1, aph(3′)-I, and mepM in E. coli TOP10 harboring the pBIC1a plasmid, highlighting their role in resistance to carbapenems, beta-lactams, aminoglycosides, and beta-lactams respectively.

The study identifies the expression of AMR genes bla KPC−2, bla TEM−1, aph(3′)-I, and mepM in E. coli TOP10 harboring the pBIC1a plasmid, highlighting their role in resistance to carbapenems, beta-lactams, aminoglycosides, and beta-lactams respectively.

The study identified multiple antimicrobial resistance genes in Salmonella Choleraesuis isolates, including aadA1, catA1, cmlA1, floR, mph(B), strA, strB, sul1, sul2, sul3, tet(A), tet(B), dfrA1, aph(3')-Ia, lnu(B), and blaTEM-1. These genes conferred resistance to various antibiotics such as streptomycin, chloramphenicol, florfenicol, erythromycin, sulfamethoxazole, tetracycline, trimethoprim, gentamicin, lincomycin, and ampicillin.

The study reports the first clinical case of a KPC-3-producing Klebsiella michiganensis isolate in Europe, highlighting the emergence of this multidrug-resistant pathogen and the significance of molecular diagnostics in identifying novel resistance mechanisms.

The study identifies multiple AMR genes and mutations in multidrug-resistant Salmonella enterica serovar Dublin isolates from Canada, highlighting the role of IS 26 in plasmid hybridization and the emergence of MDR strains.

The study evaluated the synergy of ceftazidime-avibactam (CZA) in combination with other antibiotics against multidrug-resistant Klebsiella pneumoniae and Pseudomonas aeruginosa. Several AMR genes, including blaKPC-2, blaKPC-3, blaCTX-M-15, and others, were identified as conferring resistance to CZA and other antibiotics.

The study identifies and characterizes several aminoglycoside resistance mechanisms in E. coli, including aac(3)-II, aac(6')-Ib-cr, aph(3')-Ia, and aac(3)-IId, demonstrating their roles in reducing susceptibility to aminoglycosides such as kanamycin, tobramycin, and amikacin.

The study identified several AMR genes and mutations in Salmonella enterica strains, including blaTEM-1, aph(3')-I, aph(6')-ld, dfrA5, tetA, and various arsenic resistance genes. A mutation in gyrA was also found to confer nalidixic acid resistance.

The study characterizes the resistance mechanisms of aminoglycosides, focusing on the interactions between the synthesized compound 7 and aminoglycoside-modifying enzymes such as AAC-(6′), APH-(3′), and ANT-(4′).

The study identifies multiple multidrug-resistant Salmonella enterica serovar Goldcoast strains in Taiwan, highlighting the emergence of an ST358 clone carrying various resistance genes, including blaCTX-M-55, mcr-1, and others, contributing to the rapid increase in infections.

The study identified various AMR genes and mutations in multidrug-resistant Klebsiella pneumoniae isolates, including bla KPC, bla CTX-M, bla TEM, and mutations in ompk35, ompk36, gyrA, and parC. These findings highlight the complex resistance mechanisms contributing to the persistence of MDR-Kp in the hospital setting.

The study identified bla CTX-M, bla TEM, and bla SHV as the primary ESBL genes in ESBL-producing E. coli isolates from healthy humans and swine in Northern Thailand. Additionally, several other AMR genes such as sul1, sul2, sul3, aadA22, aph(3')-Ia, strA, strB, aadA2, aadA5, qnrS1, tetA, tetB, tetD, arr2, and mefB were characterized.

The study identified multiple metallo-beta-lactamase genes, including blaNDM-1, blaIMP-26, blaIMP-4, blaIMP-1, blaVIM-4, and blaKPC-2, as major contributors to carbapenem resistance in Enterobacter cloacae isolates from three hospitals in China.

The study identified several tetracycline, macrolide, aminoglycoside, beta-lactam, sulfonamide, mercury, and biocide resistance genes in beef feedlots, catch basin water, soil, and urban sewage influent. Tetracycline resistance was predominant in beef production systems, while urban sewage influent showed a diverse resistome with resistance to multiple antimicrobial classes.

The study identified blaNDM genes as the primary cause of carbapenem resistance in Escherichia coli isolates from humans, pigs, chickens, and flies in rural China, highlighting the transmission of these resistance genes between humans and backyard animals.

The study identifies the chromosomally-encoded mcr-1 gene in a colistin-resistant E. coli ST695 strain, along with various other resistance genes such as bla NDM-1, aadA1, aadA2, aph(3')-Ia, aph(3')-VI, rmtB, cmlA1, floR, tet(A), tet(M), dfrA12, oqxA, oqxB, qnrS1, mph(A), bla TEM-105, and bla TEM-1B, contributing to its multidrug-resistant phenotype.

The study identifies various AMR genes and mutations in multidrug-resistant Staphylococcus epidermidis strains isolated from a children's hospital in Mexico City, highlighting the presence of genes such as blaZ, mecA, and others, as well as mutations in gyrA and rpoB contributing to resistance.

The study identified multiple AMR genes in extensively drug-resistant Klebsiella pneumoniae isolates, including beta-lactamases (blaSHV-11, blaTEM-1B, blaVEB-1, blaOXA-10, blaKPC-2, blaOXA-9, blaVIM-27, blaCTX-M-15, blaOXA-1, blaOXA-48), aminoglycoside resistance genes (aadA1, ant(2'')-Ia, aph(6)-Id, arr-2, aadA24, aph(3')-Ia, aph(6)-Id, aac(3)-IIa, aac(6')Ib-cr, aac(6')-Ib, aac(6')-Ib-cr), sulfonamide resistance genes (sul1, sul2), tetracycline resistance genes (tet(A), tet(G)), trimethoprim resistance genes (dfrA1, dfrA14, dfrA23), chloramphenicol resistance genes (cmlA1, catB4), and others.

The study identified multiple drug-resistant Escherichia coli isolates from a pediatric cancer hospital in Egypt, highlighting the prevalence of various antimicrobial resistance genes such as TEM-220, NDM-11, aph(6)-Id, sul2, and others, indicating a significant threat to immunocompromised patients.

The study identifies the mcr-1 gene as a key factor in colistin resistance in E. coli strains isolated from polluted rivers and wild birds. It also characterizes several other AMR genes including aadA1, aadA2, aph(3′)-Ia, aph(3″)-Ib, aph(4)-Ia, aph(6)-Id, tet(B), tet(D), tet(A), bla CTX–M–14, bla TEM–1, qnrS2, oqxA, oqxB, cmlA1, floR, vgaC, sul1, sul2, sul3, dfrA12, and glpT (E448K).

The study identified various AMR genes in CTX-M-producing E. coli isolates from peri-urban wild animals in Brazil, including bla CTX-M-55, bla CTX-M-2, bla CTX-M-15, bla CTX-M-14, and others, indicating the presence of multidrug-resistant bacteria in wildlife.

The study identifies various AMR genes in GC1 Group 1 and Outgroup Group 3 genomes, including aac(6')-Ib, aph(3')-Ia, aac(3)-IIa, sul1, sul2, tet(A), tet(G), catA1, intI1, intI2, and efflux pumps adeABC, adeIJK, and adeFGH. These genes contribute to multidrug resistance in Acinetobacter baumannii.

The study developed a multiplex PCR method for the detection of four aminoglycoside modifying enzyme resistance genes (Aac(6′)-Ib, Aac(3)-II, Ant(3″)-Ia, and Aph(3′)-Ia) in clinical strains of Escherichia coli.

The study evaluated the performance of various bioinformatics tools for predicting antimicrobial resistance (AMR) and serotypes of Salmonella enterica using whole-genome sequencing (WGS). It identified several AMR genes and mutations associated with resistance to various antibiotics.

The study identified the co-occurrence of mcr-1, mcr-3, mcr-7.1, and various clinically relevant antimicrobial resistance genes in environmental and fecal samples from a Brazilian zoo, highlighting the potential reservoir of these genes in zoological environments.

The study identified several AMR genes in a culture-negative sample from a patient with severe pneumonia, including bla SHV-12, bla KPC-2, bla TEM-1, bla CTX-M-65, aac(3)-IIa, aadA1, dfrA1, sul1, aph(3')-Ia, catA1, fosA, acrA, and rmtB, which confer resistance to various antibiotics.

The study identified several AMR genes in E. coli isolates from meat in South Africa, including aadA, strA, aph(3)-Ia, aph(3)-IIa, aac(3)-IIa, blaTEM, blaZ, ampC, cat1, cat2, cmlA1, sul1, sul2, tetA, tetB, tetC, tetD, and tetM, which confer resistance to various antibiotics such as streptomycin, kanamycin, neomycin, gentamicin, amoxicillin, ampicillin, chloramphenicol, cotrimoxazole, and tetracycline.

The study identifies various carbapenemase genes such as blaNDM-1, blaNDM-7, blaCTX-M-15, and blaOXA-181, along with other AMR genes like rmtC, sul1, aac(6')-Ib-cr, mph(A), qnrB1, and others, which contribute to resistance against multiple antibiotics in Klebsiella pneumoniae, Escherichia coli, Acinetobacter baumannii, and Pseudomonas aeruginosa in the Philippines.

The study identified multiple antimicrobial resistance genes in porcine faecal commensal E. coli, including blaTEM-1, strA, strB, tetA, dfrA12, aadA1, aadA2, cmlA, aph(3')-Ia, sul2, and sul3, which confer resistance to beta-lactams, streptomycin, tetracyclines, trimethoprim, aminoglycosides, chloramphenicol, neomycin, kanamycin, and sulfonamides.

The study identified multiple AMR genes and mutations in E. coli isolates from diseased chickens in the Czech Republic, highlighting the presence of multidrug-resistant strains with resistance to β-lactams, quinolones, sulfonamides, and tetracyclines.

The study characterizes the emergence and dominance of a minor NDM-producing Klebsiella pneumoniae population during KPC-directed therapy, highlighting challenges in detecting and managing drug-resistant subpopulations.

The study identified several AMR genes associated with different antimicrobial classes in swine fecal samples from farms with varying antimicrobial usage levels. These genes included beta-lactamases, aminoglycoside modifying enzymes, fluoroquinolone resistance genes, macrolide resistance markers, polymyxin resistance genes, phenicol resistance genes, and trimethoprim resistance genes.

The study characterizes the recombination events in the conjugative virulence plasmid p15WZ-82_Vir during transmission, identifying multiple antibiotic resistance genes and their roles in the formation of mosaic plasmids that carry both virulence and resistance traits.

The study identifies various antibiotic resistance genes in commensal E. coli isolates, highlighting the prevalence of resistance genes on F plasmids and the role of mobile genetic elements in their dissemination.

The study identified several AMR genes in stormwater samples from Stockholm, including aac(3)-X, aac(6')-I, aph(3')-I, aph(3')-IIb, bacA, chloramphenicol, rosA, ermO, abeS, major facilitator superfamily transporter, mexE, mexX, ompR, opcM, oprA, oprN, qacG, puromycin, ADP-ribosylating, dfrA12, vanH, vanR, and vanS, which confer resistance to various antibiotics such as aminoglycosides, beta-lactams, chloramphenicol, fosmidomycin, MLS, multidrug, puromycin, rifamycin, trimethoprim, and vancomycin.

The study identifies multiple AMR genes in a KPC-3-producing K. pneumoniae isolate, including blaKPC-3, aac(3)-Ib, aac(6')-Ib-cr, aph(3')-Ia, blaOXA-1, blaSHV-214, mphA, qacH, catB3, arr-3, sul1, and dfrA14, which confer resistance to various antibiotics.

The study identified multiple antibiotic resistance genes in phage-susceptible Acinetobacter baumannii strains, including sulfonamide, tetracycline, beta-lactam, aminoglycoside, macrolide, and phenicol resistance genes. These findings highlight the complex resistance profiles of these strains and their potential implications for therapeutic strategies.

The study identifies multiple antimicrobial resistance genes, including mcr-1.1 and mcr-3.1, in multidrug-resistant E. coli isolates from pigs with postweaning diarrhea in China.

The study identified 18 antibiotic resistance genes in the multidrug-resistant Proteus mirabilis strain CC15031, including genes conferring resistance to various antibiotics such as chloramphenicol, tetracycline, aminoglycosides, beta-lactams, sulfonamides, and others.

The study identified various antimicrobial resistance genes in methicillin-resistant Staphylococcus pseudintermedius (MRSP) isolates, including blaZ, erm(B), erm(C), aph(3'), ant(6), aad(6), SAT-4, cat(pc221), dfr(G), tet(K), and tet(M). These genes were associated with resistance to beta-lactams, macrolides, aminoglycosides, chloramphenicol, trimethoprim, and tetracycline.

The study identifies multiple antimicrobial resistance genes in a multidrug-resistant Salmonella enterica serovar Agona isolate from a silver gull, including bla CTX-M-55, dfrA14, sul3, qnrS1, tet(A), bla TEM-1, and others, indicating the acquisition of multidrug resistance plasmids.

The study identified several AMR genes in Salmonella enterica serovar Javiana isolates, including aac(6')-Iaa, aph(3')-Ia, sul3, and qnrB19, which confer resistance to aminoglycosides, sulfonamides, and fluoroquinolones.

The study identifies several AMR genes in Corynebacterium diphtheriae, including pbp2m associated with penicillin resistance, ermX for macrolide resistance, and various genes for tetracycline, aminoglycoside, and sulfonamide resistance.

The study identifies the blaCTX-M-15 gene as a major contributor to cephalosporin resistance in Escherichia coli isolates from Malawi, along with other AMR genes such as aac(3)-IIa, aac(3)-IId, aadA5, ant(3'')-Ih, aph(3'')-Ib, aph(3')-Ia, aph(6)-Id, strA, strB, acrF, emrD, mdtM, blaTEM-1, catA1, catB3, dfrA17, sul2, mph(A), and tet(A).

The study identifies several antimicrobial resistance (AMR) genes encoded in prophages within Acinetobacter baumannii genomes, including blaOXA-23, blaNDM-1, blaADC-5, blaOXA-67, blaOXA-115, blaTEM-12, aac(3)-I, aac(3)-Id, aacA16, aph(3')-Ia, aph(3')-VI, aph(6)-Id, aph(3'')-Ib, msr(E), mph(E), and sul2. These genes confer resistance to various antibiotics such as carbapenems, penicillins, cephalosporins, monobactams, aminoglycosides, macrolides, and sulfonamides.

The study identified multiple antibiotic resistance genes in Enteroaggregative Escherichia coli (EAEC) isolates from Egyptian children with diarrhea, including bla CTX-M-14b, bla CTX-M-15, bla TEM-1B, aadA1, aph (3')-Ib, aph (3')-Ia, aph (6)-Id, dfrA1, mdfA, sul2, and tetA, which contribute to multidrug resistance.

The study identified several β-lactamase genes, including bla CTX-M-5, bla OXA-1, bla CTX-M-15, bla CTX-M-3, and bla TEM-1, which contribute to extended-spectrum β-lactamase (ESBL) production in multidrug-resistant non-typhoidal Salmonella enterica isolates. Additionally, a mutation in the gyrA gene (D87N) was linked to quinolone resistance.

The study identified multiple antimicrobial resistance genes in bacterial isolates from chronic non-healing wounds, including beta-lactamases, aminoglycoside modifying enzymes, macrolide resistance genes, and others. These genes were found in various bacterial species such as E. coli, S. aureus, P. aeruginosa, and others.

The study identified various antimicrobial resistance genes in Salmonella isolates from Nigerian poultry, including aac(6')-Ia, aac(6')-Ib, aadA7, aph(3")-Ia, aph(3")-Ib, aph(6')-Id, aph(6')-Ic, aac(3)-Ia, aac(3)-IIa, aac(3)-IVa, aac(6')-IIa, aac(3)-Id, sul1, sul2, sul3, tet(A), tet(M), qnrS1, qnrB19, blaTEM, dfrA14, dfrA15, dfrA17, catA1, cmlA1, and floR. Mutations in gyrA (Ser83Phe, Asp87Tyr) and parC (Thr57Ser, Ser80Ile) were also associated with resistance to nalidixic acid and ciprofloxacin.

The study identified several beta-lactamase genes, including bla CTX-M-1, bla CTX-M-15, bla CTX-M-55, bla CTX-M-65, bla SHV-12, bla SHV-28, bla SHV-81, bla TEM-1B, bla TEM-52C, bla CARB-2, bla OXA-1, bla DHA-1, and bla CMY-2, along with other AMR genes such as aac(3)-IIa, aac(6')-Ib-cr, aph(3')-Ia, aph(3')-Ib, aph(6)-Id, aadA1, aadA2, aph(4)-Ia, oqxA, oqxB, qnrB1, qnrS1, floR, sul2, sul1, tet(A), dfrA14, dfrA1, dfrA17, dfrA8, dfrA12, dfrA16, dfrA15, catB3, cmlA1, arr-2, and qnrB19, which confer resistance to various antibiotics in Escherichia coli and Klebsiella pneumoniae isolated from food products.

The study identified various carbapenemase genes (blaNDM-1, blaNDM-5, blaVIM-1, blaVIM-6, blaOXA-23, blaOXA-58, blaOXA-66, blaOXA-69, blaOXA-91, blaOXA-181, blaOXA-50) and other resistance genes (such as armA, rmtC, rmtF, aac(3)-I, aadA1, aph(3')-Ia, aph(3')-VI, aph(3')-Via, aph(6')-Id, mphE, msrE, mphA, ereA, dfrA1, dfrA12, dfrA14, dfrA17, dfrA20, sul1, sul2, tetB, tetD, tetG, tet39, qnrVC1, qnrS1, qnrB4, floR, catA1, catA2, catB3, catB7, cmlA1, cmlA5, arr-3, arr-2, sat2, acrF, mdtM, emrD, mexA, mexE, mexX, kdeA, oxa-10, oxa-395, oxa-396, oxa-846, adc-25, dha-1, act-16, cmY, ctx-m-15, shv-67, tem-1b) in carbapenem non-susceptible clinical isolates of gram-negative bacteria in Kenya, highlighting the diversity and prevalence of multidrug resistance.

The study identified NDM-1, TEM-1B, and SHV-12 carbapenemase genes along with various other AMR genes in Leclercia adecarboxylata isolates causing an outbreak linked to contaminated TPN.

The study identifies a carbapenem-resistant Klebsiella pneumoniae isolate carrying the plasmid-mediated AmpC gene blaDHA-1, along with other resistance genes such as blaOXA-1, aac(6')-Ib-cr, aph(3')-Ia, sul1, oqxA, oqxB, qnrB4, arr-3, tet(A), catB3, mph(A), fosA, IncFIB(K), and IncR.

This study identified several antimicrobial resistance genes in Pasteurella multocida, including aminoglycoside, beta-lactam, tetracycline, macrolide, and sulfonamide resistance genes, highlighting the diverse resistance mechanisms present in this pathogen.

The study reports the emergence of a high-level carbapenem-resistant and extensively drug-resistant (XDR) Escherichia coli strain N7 producing NDM-5, highlighting the presence of multiple resistance genes on plasmids and chromosomes.

The study identifies various ESBL and AmpC beta-lactamase genes, including bla SHV-12, bla CTX-M-1, bla CTX-M-2, bla CTX-M-14, bla CTX-M-15, bla TEM-52, and bla CMY-2, along with the mcr-1 gene conferring colistin resistance in E. coli isolates from food animals in Europe.

Six unique resistance plasmids were identified that can transfer to Salmonella typhimurium, Klebsiella aerogenes, and E. coli, carrying 3-6 antibiotic resistance genes conferring resistance to 2-4 antibiotic classes.

The study identified several antibiotic resistance genes in Staphylococcus aureus isolates from bulk tank milk samples, including norA, aph(3')-Ia, blaZ, and mecA. These genes conferred resistance to fluoroquinolones, aminoglycosides, beta-lactams, and methicillin, respectively.

The study identified several AMR genes in carbapenem-resistant Acinetobacter baumannii strains from Vietnam, including bla OXA-51-like, bla OXA-23, bla TEM-1, and others, highlighting the widespread resistance to beta-lactams, aminoglycosides, and other antibiotics.

The study identified various AMR genes and mutations in E. coli isolates from different animal sources, highlighting the presence of ESBL genes such as bla CTX-M-15, bla TEM-1B, and bla CMY-28, as well as mutations in parC and gyrA that confer resistance to fluoroquinolones.

The study identified various AMR genes and mutations in E. coli isolates from different animal sources, highlighting the presence of ESBL genes such as bla CTX-M-15, bla TEM-1B, and bla CMY-28, as well as mutations in parC and gyrA that confer resistance to fluoroquinolones.

The study identified several aminoglycoside resistance genes, including aph(3')-VI, aac(6')-Ib, aac(3)-II, aph(3')-Ia, and armA, in Acinetobacter baumannii isolates from Qazvin, Iran. These genes were associated with high levels of resistance to aminoglycosides such as gentamicin, tobramycin, and amikacin.

The study identifies several beta-lactamases, aminoglycoside modifying enzymes, and efflux pumps involved in resistance to beta-lactams, aminoglycosides, and fluoroquinolones in E. coli and K. pneumoniae using proteogenomics.

The paper discusses the presence of various antibiotic resistance genes in Vibrio species, including strB, sul2, tetA, blaTEM, qnrA, ermB, floR, aac(3)-IIa, blaNDM-1, blaCMY, blaP1, catB3, and others, which confer resistance to antibiotics such as streptomycin, sulfamethoxazole, tetracycline, ampicillin, fluoroquinolones, erythromycin, florfenicol, gentamicin, carbapenems, chloramphenicol, and trimethoprim.

The study characterizes the mcr-1 gene and various other resistance genes in Escherichia coli isolates from animal organs with lesions, highlighting their multidrug resistance profiles and the genetic features of plasmids carrying these genes.

Solar photo-Fenton treatment effectively removed a wide range of antibiotic resistance genes (ARGs) including those conferring resistance to sulfonamides, macrolides, tetracyclines, and beta-lactams. The study identified several ARGs such as sul1, sul2, tet(X), erm(F), mph(A), mph(E), msr(E), aadA, aph(3"), aph(6), strA, and blaBKC.

The study identifies multiple antimicrobial resistance genes in the multidrug-resistant K. pneumoniae strain KPE16, including bla NDM-1, bla CTX-M-15, and various aminoglycoside, sulfonamide, and tetracycline resistance genes. Additionally, chromosomal mutations in ompK36, ompK37, and acrR contribute to resistance.

The study identifies several genes involved in antibiotic resistance in Mycobacterium abscessus, including erm(41) for macrolide resistance, WhiB7 for general resistance to ribosome-targeting antibiotics, sigH for tigecycline resistance, cydA for clofazimine tolerance, and various aminoglycoside-modifying enzymes like aac(2'), aph(3'), and eis2.

The study characterizes a pESI-like plasmid harboring multiple resistance genes, including bla CTX-M-65, in multidrug-resistant Salmonella enterica Infantis isolates from England and Wales. The plasmid was associated with resistance to beta-lactams, aminoglycosides, chloramphenicol, tetracyclines, trimethoprim, sulfonamides, fosfomycin, and heavy metals.

The study identifies aminoglycoside-resistance genes such as aac(6')-Ib, aac(6')-Ib', aac(3)-II, aac(3)-IV, ant(2'')-I, aph(3')-I, and rmtF as significant predictors of aminoglycoside MICs in carbapenem-resistant Klebsiella pneumoniae.

The study identified several ESBL genes, colistin resistance genes, and other AMR genes in ESBL-producing E. coli from pigs and pig farm workers in Vietnam. Key findings include the prevalence of bla CTX-M-55, bla CTX-M-14, and bla CTX-M-27, along with mcr-1 and mcr-3 for colistin resistance, and various other resistance genes for aminoglycosides, quinolones, tetracyclines, chloramphenicol, macrolides, and sulfonamides.

The study analyzed 22,102 Salmonella genomes from public databases to track antimicrobial resistance (AMR) trends in food animals in the United States. It found that the prevalence of multidrug resistance (MDR) decreased in bovines and swine but increased in poultry. Key AMR genes identified include bla CMY-2, bla CTX-M-65, floR, tetA, sul2, aadA2, aac(3)-VIa, qnrB19, qnrB2, bla SHV-12, bla TEM-1, bla CARB-2, aph(3")-Ib, aph(6)-Id, aph(3')-Ia, ant(3")-Ia, aph(4)-Ia, and aac(3)-IVa. A significant mutation, gyrA D87Y, was associated with quinolone resistance in poultry.

The study identified several AMR genes, including bla CMY-2, floR, sul2, and tetA, in Salmonella enterica isolates from dairy cattle. These genes confer resistance to various antibiotics such as cephalosporins, florfenicol, sulfamethoxazole-trimethoprim, and tetracycline.

The study identified multiple antimicrobial resistance genes, including bla NDM-5, bla OXA-10, and bla TEM-1B, in NDM-5-producing Enterobacteriaceae isolates from an urban river in China. These genes conferred resistance to various antibiotics such as carbapenems, cephalosporins, quinolones, and aminoglycosides.

The study identified Klebsiella variicola and Klebsiella pneumoniae strains carrying multiple resistance genes, including bla KPC-2, bla TEM-1A, bla LEN17, aadA16, arr-3, qnrB4, oqxA/B, dfrA27, sul1, tetD, fosA, qacEΔ1, bla CTX-M-3, bla TEM-1B, bla CTX-M-65, bla SHV-27, aac(6')-IIa, rmtB, aph(3')-Ia, aadA16, qnrS1, aac(6')-Ib-cr, qnrB91, oqxA/B, mph(A), tet(A), fosA, dfrA27, and two copies of qacEΔ1-sul1.

The study identified several antimicrobial resistance genes in Herbaspirillum frisingense clinical strain AU14559, including beta-lactamases and vanS/R genes involved in vancomycin resistance. These findings highlight the potential for multidrug resistance in this species.

The study identifies various AMR genes and mutations associated with colistin resistance in clinical Acinetobacter baumannii strains, highlighting the genomic diversity and mosaicism in resistance mechanisms.

The study identified multidrug-resistant Pasteurella multocida type B:2 strains in fowl cholera cases in Bangladesh, highlighting the presence of various virulence factors and antimicrobial resistance genes.

The study identified various AMR genes in two multidrug-resistant Acinetobacter baumannii strains, ACC001 and ACC002, including aminoglycoside resistance genes, tetracycline resistance genes, beta-lactamases, and sulfonamide resistance genes. These genes contribute to resistance against multiple antibiotics such as gentamicin, tobramycin, tetracycline, penicillins, cephalosporins, and sulfonamides.

The study identified several AMR genes, including novel bla ADC-257, and mutations in gyrA and parC associated with fluoroquinolone resistance in extensively drug-resistant NDM-producing Acinetobacter baumannii isolates.

The study reports the first bovine ST361 NDM-5 positive Escherichia coli in Greece, highlighting the importation of multidrug-resistant strains and the need for continued surveillance.

The study identifies a multidrug-resistant (MDR) Salmonella Heidelberg outbreak linked to dairy calf exposure, highlighting the presence of plasmid-borne resistance genes such as aadA1, aph(3')-Ia, bla CMY-2, floR, fosA7, qnrB19, strA, strB, sull, sul2, tet(A), tet(B), tet(O), and a novel gene dfrA34.

The study identifies multiple plasmid-borne AMR genes, including blaTEM-1, aph(3')-I, floR, and tetA, which confer resistance to ampicillin, kanamycin, chloramphenicol, and tetracycline, respectively. These genes are primarily located on conjugative plasmids and show potential for horizontal transfer between WWTP- and human/animal-associated bacteria.

The study identified several aminoglycoside resistance genes, including aac(6')-Ib, aph(3')-VIe, aadA15, aph(3')-Ia, aph(3')-II, and aph(6), which were prevalent among Gram-negative bacteria isolates in Iran.

The study shows that IS26-mediated amplification of blaKPC-2 leads to carbapenem hyperresistance in E. coli. The amplification of blaKPC-2 was found to be mediated by IS26, and the copy number of blaKPC-2 was positively correlated with antibiotic concentration.

Flavophospholipol (FPL) effectively reduced the abundance of tetracycline-resistant Escherichia coli in pig feces by inhibiting conjugational transfer and growth of resistant plasmids carrying tetA, tetB, blaTEM-1B, mdfA, aph(3')-I, sul2, aadA1, and dfrA1.

The study evaluated the combination of flomoxef and fosfomycin for treating neonatal sepsis in settings with high antimicrobial resistance. It found that the combination showed synergy in bacterial killing and prevented the emergence of fosfomycin resistance. Specific AMR genes and mutations were identified in Enterobacterales strains, including beta-lactamases and efflux pumps.

The study characterizes a conjugative multidrug resistance IncP-2 megaplasmid, pPAG5, from a clinical Pseudomonas aeruginosa isolate, identifying multiple AMR genes and resistance regions.

Early-life broad-spectrum antibiotics alter the infant gut microbiome and resistome, with amoxicillin + cefotaxime having the most significant impact on AMR gene profiles.

The study identified multiple antimicrobial resistance genes in multidrug-resistant Salmonella serovar Kentucky ST198 isolates from Spain, including genes conferring resistance to aminoglycosides, beta-lactams, sulfonamides, tetracyclines, trimethoprim, and colistin.

The study identified various AMR genes in two extensively drug-resistant A. baumannii isolates, including aminoglycoside resistance genes, sulfonamide resistance genes, beta-lactamase genes, and efflux pump genes, highlighting the complexity of their resistance mechanisms.

The study identifies two new species, Corynebacterium parakroppenstedtii and Corynebacterium pseudokroppenstedtii, and characterizes antibiotic resistance genes including APH(3')-Ia, APH(3'')-Ib, APH(6)-Id, erm(X), sul1, and tet(W) in C. kroppenstedtii-like isolates.

The study identifies multiple antimicrobial resistance genes (ARGs) in highly drug-resistant Escherichia coli isolates from veal calves, including blaCMY-2, blaCTX-M-15, mph(A), erm(B), aac(6')-Ib-cr, qnrS1, aadA5, aadA1, aph(3')-Ic, aph(3')-Ia, aph(3')-Ib, aph(6')-Id, sul1, sul2, tet(A), and tet(B). Additionally, mutations in gyrA (S83L, D87N) and parC (A56T) were found to contribute to fluoroquinolone resistance.

The study identified 361 genes associated with antimicrobial resistance in E. coli isolates from poultry farms and slaughterhouses, highlighting extensive gene sharing and multidrug resistance profiles across hosts and environments.