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aph(3')-Vc

aminoglycoside O-phosphotransferase APH(3')-Vc

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to aph(3')-Vc

Browse AMR rules for aph(3')-Vc

Validation StatusConfirmed2+ DBs

Overview

Mechanism: Enzymatic modification
Drug Classes: PAROMOMYCIN, RIBOSTAMYCIN, NEOMYCIN, AMINOGLYCOSIDE
Organisms: Micromonospora chalcea
Alleles: 2
Papers: 1
Databases: Card DatabaseReference Gene CatalogResFinder Database

Allele Variants2

Allele	Database	Papers	Drug Classes	Organisms	Countries	Years	Sequence Accession	Protein Accession
APH(3')-Vc	Card DatabaseReference Gene CatalogResFinder Database	3	PAROMOMYCIN, RIBOSTAMYCIN +2	Micromonospora chalcea	-	1991	S81599.1	AAB21326.1
aph(3')-Vc	ResFinder Database	1	PAROMOMYCIN, NEOMYCIN +1	-	-	1991	S81599	-

Papers1

1

Isolation and characterisation of an aminoglycoside phosphotransferase from neomycin-producing Micromonospora chalcea; comparison with that of Streptomyces fradiae and other producers of 4,6-disubstituted 2-deoxystreptamine antibiotics.

PMID 1663923 · 1991

Gene Information

Gene Name: aph(3')-Vc
Allele: APH(3')-Vc
Encodes: aminoglycoside O-phosphotransferase APH(3')-Vc
Source Database: Reference Gene Catalog
Mechanism: Enzymatic modification
Confers Resistance To: PAROMOMYCINRIBOSTAMYCINNEOMYCINAMINOGLYCOSIDE
Organisms Tested In: • Micromonospora chalcea
Sequence Accession: S81599.1
Protein Accession: AAB21326.1
Notes: ARO:3002651

2

Isolation and characterisation of an aminoglycoside phosphotransferase from neomycin-producing Micromonospora chalcea; comparison with that of Streptomyces fradiae and other producers of 4,6-disubstituted 2-deoxystreptamine antibiotics.

PMID 1663923 · 1991

Gene Information

Gene Name: aph(3')-Vc
Allele: APH(3')-Vc
Encodes: aminoglycoside O-phosphotransferase APH(3')-Vc
Source Database: ResFinder Database
Mechanism: Enzymatic modification
Confers Resistance To: PAROMOMYCINRIBOSTAMYCINNEOMYCINAMINOGLYCOSIDE
Organisms Tested In: • Micromonospora chalcea
Sequence Accession: S81599.1
Protein Accession: AAB21326.1
Notes: ARO:3002651

3

Isolation and characterisation of an aminoglycoside phosphotransferase from neomycin-producing Micromonospora chalcea; comparison with that of Streptomyces fradiae and other producers of 4,6-disubstituted 2-deoxystreptamine antibiotics.

PMID 1663923 · 1991

Gene Information

Gene Name: aph(3')-Vc
Allele: APH(3')-Vc
Encodes: aminoglycoside O-phosphotransferase APH(3')-Vc, APH(3')
Source Database: Card Database
Mechanism: Enzymatic modification, antibiotic inactivation
Confers Resistance To: PAROMOMYCINRIBOSTAMYCINNEOMYCINAMINOGLYCOSIDE
Organisms Tested In: • Micromonospora chalcea
Sequence Accession: S81599.1
Protein Accession: AAB21326.1
Notes: ARO:3002651

4

Isolation and characterisation of an aminoglycoside phosphotransferase from neomycin-producing Micromonospora chalcea; comparison with that of Streptomyces fradiae and other producers of 4,6-disubstituted 2-deoxystreptamine antibiotics.

PMID 1663923 · 1991

Gene Information

Gene Name: aph(3')-Vc
Allele: aph(3')-Vc
Source Database: ResFinder Database
Mechanism: Enzymatic modification
Confers Resistance To: PAROMOMYCINNEOMYCINRIBOSTAMYCIN
Sequence Accession: S81599

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