aph(3) c

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phosphotransferase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

UniProt

Protein entries specific to aph(3) c

AMR Rules

Browse AMR rules for aph(3) c

Validation StatusCandidate

Overview

Mechanism: modifies aminoglycoside antibiotics by adding a phosphate group, leading to resistance
Validation Method: PCR genotyping
Drug Classes: gentamicin, kanamycin, streptomycin
Organisms: Acinetobacter, Aeromonas, Alcaligenes, Bacillus, Bordetella, Brevundimonas, Chromobacterium, Klebsiella, Leucobacter, Morganella, Proteus, Providencia, Psychrobacter, Serratia, uncultured bacteria
Geographic Location: Southwestern Nigeria
Papers: 1
Databases: Reslit

Papers1

Genotypic Characterization of Aminoglycoside Resistance Genes from Bacteria Isolates in Selected Municipal Drinking Water Distribution Sources in Southwestern Nigeria.

PMID 31447500 · 2019

The study identified the presence of aminoglycoside resistance genes aph(3") c, ant(3") b, and aph(6)-1d d in various bacteria isolated from municipal drinking water distribution systems in southwestern Nigeria, highlighting the potential for these genes to spread through mobile genetic elements.

Gene Information

Gene Name: aph(3) c
Allele: aph(3") c
Encodes: phosphotransferase
Source Database: Reslit
Mechanism: modifies aminoglycoside antibiotics by adding a phosphate group, leading to resistance
Confers Resistance To: gentamicinkanamycinstreptomycin
Organisms Tested In: • Acinetobacter
• Aeromonas
• Alcaligenes
• Bacillus
• Bordetella
• Brevundimonas
• Chromobacterium
• Klebsiella
• Leucobacter
• Morganella
• Proteus
• Providencia
• Psychrobacter
• Serratia
• uncultured bacteria
Geographic Location: Southwestern Nigeria
Validation Method: PCR genotyping

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aph(3) c

View on PubMed

phosphotransferase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

UniProt

Protein entries specific to aph(3) c

AMR Rules

Browse AMR rules for aph(3) c

Validation StatusCandidate

Overview

Mechanism: modifies aminoglycoside antibiotics by adding a phosphate group, leading to resistance
Validation Method: PCR genotyping
Drug Classes: gentamicin, kanamycin, streptomycin
Organisms: Acinetobacter, Aeromonas, Alcaligenes, Bacillus, Bordetella, Brevundimonas, Chromobacterium, Klebsiella, Leucobacter, Morganella, Proteus, Providencia, Psychrobacter, Serratia, uncultured bacteria
Geographic Location: Southwestern Nigeria
Papers: 1
Databases: Reslit

Papers1

Genotypic Characterization of Aminoglycoside Resistance Genes from Bacteria Isolates in Selected Municipal Drinking Water Distribution Sources in Southwestern Nigeria.

PMID 31447500 · 2019

Gene Information

Gene Name: aph(3) c
Allele: aph(3") c
Encodes: phosphotransferase
Source Database: Reslit
Mechanism: modifies aminoglycoside antibiotics by adding a phosphate group, leading to resistance
Confers Resistance To: gentamicinkanamycinstreptomycin
Organisms Tested In: • Acinetobacter
• Aeromonas
• Alcaligenes
• Bacillus
• Bordetella
• Brevundimonas
• Chromobacterium
• Klebsiella
• Leucobacter
• Morganella
• Proteus
• Providencia
• Psychrobacter
• Serratia
• uncultured bacteria
Geographic Location: Southwestern Nigeria
Validation Method: PCR genotyping

Comments (0)

No comments yet. Be the first to comment!

aph(3) c

Gene Information

Browse AMR Genes

aph(3) c

Gene Information