aph1

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aminoglycoside phosphotransferase

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UniProt

Protein entries specific to aph1

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Validation StatusCandidate

Overview

Validation Method: whole-genome sequencing and RT-PCR
Drug Classes: streptomycin
Organisms: Pseudomonas sp. B14-6
Geographic Location: High Arctic Svalbard
Papers: 1
Databases: Reslit

Papers1

Arctic Psychrotolerant Pseudomonas sp. B14-6 Exhibits Temperature-Dependent Susceptibility to Aminoglycosides.

PMID 36009888 · 2022

The study identifies two aminoglycoside phosphotransferase genes, aph1 and aph2, as the primary contributors to streptomycin resistance in the psychrotolerant bacterium Pseudomonas sp. B14-6. These genes were experimentally validated through whole-genome sequencing and RT-PCR.

Gene Information

Gene Name: aph1
Allele: aph1
Encodes: aminoglycoside phosphotransferase
Source Database: Reslit
Confers Resistance To: streptomycin
Organisms Tested In: • Pseudomonas sp. B14-6
Geographic Location: High Arctic Svalbard
Validation Method: whole-genome sequencing and RT-PCR
Sequence Accession: CP053929

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aph1

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aph1

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