aph51

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Aminoglycoside phosphotransferase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

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UniProt

Protein entries specific to aph51

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Validation StatusCandidate

Overview

Validation Method: genomic analysis
Drug Classes: aminoglycosides
Organisms: Microbacterium yannicii, Microbacterium yannicii G72T
Geographic Location: France
Papers: 1
Databases: Reslit

Papers1

Phenotypic and genotypic properties of Microbacterium yannicii, a recently described multidrug resistant bacterium isolated from a lung transplanted patient with cystic fibrosis in France.

PMID 23642186 · 2013

The study identifies a new erm43 gene encoding a 23S rRNA N-6-methyltransferase responsible for erythromycin resistance in Microbacterium yannicii. Additionally, mutations in gyrA (S83A) and parC (S80A) contribute to fluoroquinolone resistance, while ampC, aph51, and dhps genes are associated with beta-lactam, aminoglycoside, and sulfamethoxazole-trimethoprim resistance, respectively.

Gene Information

Gene Name: aph51
Allele: aph51
Encodes: Aminoglycoside phosphotransferase
Source Database: Reslit
Confers Resistance To: aminoglycosides
Organisms Tested In: • Microbacterium yannicii
• Microbacterium yannicii G72T
Geographic Location: France
Validation Method: genomic analysis
Sequence Accession: FN547412|CAJF01000001-CAJF01000067

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aph51

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aph51

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