aph6/str(b)

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adenine phosphotransferase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

UniProt

Protein entries specific to aph6/str(b)

AMR Rules

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Validation StatusCandidate

Overview

Mechanism: confers resistance to aminoglycosides
Validation Method: microarray and PCR
Drug Classes: gentamicin, tobramycin
Organisms: Klebsiella pneumoniae
Geographic Location: Kenya
Papers: 1
Databases: Reslit

Papers1

Antimicrobial resistance of Klebsiella pneumoniae stool isolates circulating in Kenya.

PMID 28575064 · 2017

The study identified 46 AMR genes or gene families in 90 Klebsiella pneumoniae isolates from Kenya, highlighting the prevalence of multidrug resistance and the diversity of resistance mechanisms.

Gene Information

Gene Name: aph6/str(b)
Allele: aph6/str(B)
Encodes: adenine phosphotransferase
Source Database: Reslit
Mechanism: confers resistance to aminoglycosides
Confers Resistance To: gentamicintobramycin
Organisms Tested In: • Klebsiella pneumoniae
Geographic Location: Kenya
Validation Method: microarray and PCR
Sequence Accession: NCBI Accession no. KX377894|KX377894

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aph6/str(b)

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aph6/str(b)

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