aphB

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aminoglycoside phosphotransferase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

UniProt

Protein entries specific to aphB

AMR Rules

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Validation StatusCandidate

Overview

Mechanism: phosphorylation of aminoglycosides
Validation Method: whole-genome sequencing
Drug Classes: aminoglycosides
Organisms: Pseudomonas spp.
Geographic Location: Norway|China
Papers: 1
Databases: Reslit

Papers1

Antibiotic Resistance and Phylogeny of Pseudomonas spp. Isolated over Three Decades from Chicken Meat in the Norwegian Food Chain.

PMID 33498315 · 2021

The study identified several AMR genes and mutations in Pseudomonas spp. isolated from chicken meat in Norway, including beta-lactamases, efflux pumps, and genes involved in resistance to aminoglycosides, fluoroquinolones, and colistin.

Gene Information

Gene Name: aphB
Allele: aphB
Encodes: aminoglycoside phosphotransferase
Source Database: Reslit
Mechanism: phosphorylation of aminoglycosides
Confers Resistance To: aminoglycosides
Organisms Tested In: • Pseudomonas spp.
Geographic Location: Norway|China
Validation Method: whole-genome sequencing
Sequence Accession: PRJNA685056

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aphB

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aphB

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