Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
ADP-ribosyl transferase
Overview
Analysis of the resistome of a multidrug-resistant NDM-1-producing Escherichia coli strain by high-throughput genome sequencing.
The study identified multiple AMR genes in a multidrug-resistant E. coli strain, including blaNDM-1, blaTEM-1, blaCTX-M-15, and others, along with chromosomal mutations in gyrA, parC, ompC, and ompF contributing to resistance.
The initial state of the human gut microbiome determines its reshaping by antibiotics.
The study identified various beta-lactamase genes such as bla CfxA-6, bla TEM-1, bla OXA-32, bla OXA-54, bla OXA-192, bla ROB-1, bla HOA-1, bla HGC-2, bla GOB-1, bla ACT-1, bla ACT-7, bla AmpC-HG5, arr2, bla CepA, and mef (G) that were enriched after cefprozil treatment. These genes conferred resistance to beta-lactams and other antibiotics, highlighting the dynamic nature of the gut resistome in response to antibiotic exposure.
Interaction of Acinetobacter baumannii with Human Serum Albumin: Does the Host Determine the Outcome?
The study identified several antibiotic resistance genes in Acinetobacter baumannii, including clmA, pbp1, pbp3, blaPER-7, aac(6a)-Ib, ant(2n)-Ia, armA, aphA6, sul1, and arr2, which were upregulated or downregulated in response to human serum albumin (HSA) and human serum (HS).
Molecular study of metallo-β-lactamases and integrons in Acinetobacter baumannii isolates from burn patients.
High prevalence of MBLs genes, especially blaVIM, was identified in MDR A. baumannii isolates. Most of the strains carried class 1 integrons, and gene cassettes arrays including cmlA5 and cmlA7 were detected for the first time in A. baumannii strains in Iran.
Antimicrobial Resistance and Virulence Characteristics of Klebsiella pneumoniae Isolates in Kenya by Whole-Genome Sequencing.
The study identified several AMR genes in K. pneumoniae isolates from Kenya, including blaCTX-M-15, blaTEM-181, blaOXA-181, blaNDM-1, mcr-8, armA, rmtF, aac(6')-Ib-cr, aph(3")-ib, aph(6)-id, dfrA, sul2, qnrB, tetA, and catII, which confer resistance to various antibiotics such as beta-lactams, carbapenems, aminoglycosides, fluoroquinolones, tetracyclines, and chloramphenicol.
Characterization of metal(loid)s and antibiotic resistance in bacteria of human gut microbiota from chronic kidney disease subjects.
The study identified several antibiotic and metal(loid) resistance genes in gut microbiota from chronic kidney disease (CKD) subjects, including genes encoding beta-lactamases, quinolone resistance proteins, macrolide phosphotransferases, and efflux pumps. Additionally, genes conferring resistance to arsenicals and heavy metals were detected.
Investigation of multidrug-resistant plasmids from carbapenemase-producing Klebsiella pneumoniae clinical isolates from Pakistan.
The study identified 34 antimicrobial resistance genes (ARGs) in multidrug-resistant (MDR) plasmids from carbapenemase-producing Klebsiella pneumoniae clinical isolates in Pakistan, including bla NDM-1, bla OXA-48, and various beta-lactamases, aminoglycoside resistance genes, and others.
Determinants of Antibiotic Resistance and Virulence Factors in the Genome of Escherichia coli APEC 36 Strain Isolated from a Broiler Chicken with Generalized Colibacillosis.
The study identifies multiple antibiotic resistance genes in the E. coli APEC 36 strain, including beta-lactamases, aminoglycoside modifying enzymes, fluoroquinolone resistance genes, and efflux pumps, indicating a high level of multidrug resistance.
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