asmA

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modulates porins, glycerophosphates and LPS levels in the outer membrane

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Validation StatusCandidate

Overview

Mechanism: unknown
Validation Method: mutant analysis
Drug Classes: polymyxin b
Organisms: Yersinia pestis
Papers: 1
Databases: Reslit

Papers1

Tn5AraOut mutagenesis for the identification of Yersinia pestis genes involved in resistance towards cationic antimicrobial peptides.

PMID 21575704 · 2011

The study identifies several Yersinia pestis genes involved in resistance to cationic antimicrobial peptides (CAMPs), including asmA, hflC, pbgP, mglB, feoC, pitA, glpQ-like, and y1522. These genes contribute to resistance against polymyxin B, protamine, and other CAMPs.

Gene Information

Gene Name: asmA
Allele: asmA
Encodes: modulates porins, glycerophosphates and LPS levels in the outer membrane
Source Database: Reslit
Mechanism: unknown
Confers Resistance To: polymyxin b
Organisms Tested In: • Yersinia pestis
Validation Method: mutant analysis

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asmA

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asmA

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