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bceB

transporter

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to bceB

Browse AMR rules for bceB

Overview

Mechanism: low signal output
Drug Classes: bacitracin
Organisms: Bacillus subtilis
Papers: 1
Mutations: 9

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
A301T	-	low signal output	Bacillus subtilis	bacitracin	Reslit	Candidate
R83W	-	altered sensitivity	Bacillus subtilis	bacitracin	Reslit	Candidate
M551I	-	low signal output	Bacillus subtilis	bacitracin	Reslit	Candidate
V619M	-	low signal output	Bacillus subtilis	bacitracin	Reslit	Candidate
S219F	-	no activity	Bacillus subtilis	bacitracin	Reslit	Candidate
G215R	-	no activity	Bacillus subtilis	bacitracin	Reslit	Candidate
G525R	-	no activity	Bacillus subtilis	bacitracin	Reslit	Candidate
S542L	-	altered sensitivity	Bacillus subtilis	bacitracin	Reslit	Candidate
C544Y	-	no activity	Bacillus subtilis	bacitracin	Reslit	Candidate

Papers1

1

Identification of regions important for resistance and signalling within the antimicrobial peptide transporter BceAB of Bacillus subtilis.

PMID 23687272 · 2013

Mutations in bceB affecting resistance and signaling to the histidine kinase.

Mutation Information

bceB: p.A301T bceB: p.R83W bceB: p.M551I bceB: p.V619M bceB: p.S219F bceB: p.G215R bceB: p.G525R bceB: p.S542L bceB: p.C544Y

Protein Change: A301T, R83W, M551I, V619M, S219F, G215R, G525R, S542L, C544Y
Organisms: Bacillus subtilis
Confers Resistance To: bacitracin
Effect on Function: low signal output; altered sensitivity; no activity
Validation Method: mutagenesis and resistance testing
Source Database: Reslit